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Cheap flights from Des Moines to Phoenix from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Phoenix departing on 4/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Phoenix

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:17 pm - 6:11 pm
DSM
-
PHX
23h 54m
1 stop
Frontier Logo
8:04 pm - 6:42 pm
PHX
-
DSM
21h 38m
2 stops
$231Frontier
Fri, Feb 20 - Wed, Feb 25
Multiple Airlines Logo
7:17 pm - 8:42 am
DSM
-
PHX
14h 25m
1 stop
Multiple Airlines Logo
5:05 am - 7:48 pm
PHX
-
DSM
13h 43m
2 stops
$232Multiple Airlines
Mon, Feb 16 - Fri, Feb 20
Frontier Logo
7:17 pm - 6:11 pm
DSM
-
PHX
23h 54m
1 stop
Frontier Logo
5:05 am - 6:32 pm
PHX
-
DSM
12h 27m
2 stops
$233Frontier
Fri, Feb 20 - Mon, Feb 23
Frontier Logo
7:17 pm - 12:41 am
DSM
-
PHX
6h 24m
1 stop
Frontier Logo
6:00 am - 6:19 pm
PHX
-
DSM
11h 19m
1 stop
$234Frontier
Mon, Feb 16 - Fri, Feb 20
Frontier Logo
8:21 pm - 8:42 am
DSM
-
PHX
13h 21m
1 stop
Frontier Logo
9:24 pm - 7:16 pm
PHX
-
DSM
19h 52m
1 stop
$235Frontier
Fri, Mar 6 - Sun, Mar 15
Frontier Logo
7:59 pm - 12:41 am
DSM
-
PHX
5h 42m
1 stop
Frontier Logo
6:00 am - 6:32 pm
PHX
-
DSM
11h 32m
1 stop
$236Frontier
Fri, Feb 27 - Mon, Mar 2
Allegiant Air Logo
11:15 am - 12:23 pm
DSM
-
AZA
3h 08mnonstop
Allegiant Air Logo
10:00 am - 3:58 pm
AZA
-
DSM
27h 58m
1 stop
$237Allegiant Air
Wed, Apr 1 - Sun, Apr 5
Delta Logo
10:28 am - 6:18 pm
DSM
-
PHX
9h 50m
1 stop
Delta Logo
11:55 pm - 10:48 am
PHX
-
DSM
8h 53m
1 stop
$239Delta
Tue, Mar 17 - Tue, Mar 24
Allegiant Air Logo
3:37 pm - 4:45 pm
DSM
-
AZA
3h 08mnonstop
Allegiant Air Logo
5:30 pm - 10:11 pm
AZA
-
DSM
2h 41mnonstop
$240Allegiant Air
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
6:23 pm - 7:35 pm
DSM
-
PHX
3h 12mnonstop
American Airlines Logo
7:02 pm - 11:59 pm
PHX
-
DSM
2h 57mnonstop
$244American Airlines
Tue, Mar 31 - Sat, Apr 4

American Airlines flights from Des Moines to Phoenix

Our best American Airlines deals on Des Moines to Phoenix flight tickets
American Airlines
Mar 31
DSM6:23 pmDes Moines
3h 12m
PHX7:35 pmPhoenix Sky Harbor Intl
Apr 4
PHX7:02 pmPhoenix Sky Harbor Intl
2h 57m
DSM11:59 pmDes Moines
$244
American Airlines
Apr 5
DSM11:17 amDes Moines
8h 05m
1 stop
PHX5:22 pmPhoenix Sky Harbor Intl
Apr 11
PHX12:40 pmPhoenix Sky Harbor Intl
2h 49m
DSM5:29 pmDes Moines
$266
American Airlines
Mar 17
DSM6:23 pmDes Moines
3h 12m
PHX7:35 pmPhoenix Sky Harbor Intl
Mar 25
PHX12:54 pmPhoenix Sky Harbor Intl
2h 49m
DSM5:43 pmDes Moines
$272

Southwest flights from Des Moines to Phoenix

Our best Southwest deals on Des Moines to Phoenix flight tickets
Southwest
Mar 4
DSM8:35 amDes Moines
8h 00m
1 stop
PHX3:35 pmPhoenix Sky Harbor Intl
Mar 11
PHX10:10 amPhoenix Sky Harbor Intl
2h 45m
DSM2:55 pmDes Moines
$279
Southwest
Mar 17
DSM12:15 pmDes Moines
7h 50m
1 stop
PHX6:05 pmPhoenix Sky Harbor Intl
Mar 25
PHX10:10 amPhoenix Sky Harbor Intl
2h 45m
DSM2:55 pmDes Moines
$282
Southwest
Jan 31
DSM3:35 pmDes Moines
3h 15m
PHX5:50 pmPhoenix Sky Harbor Intl
Feb 4
PHX2:10 pmPhoenix Sky Harbor Intl
4h 10m
1 stop
DSM7:20 pmDes Moines
$334

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Phoenix that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 24, 2026.
Use the filters below to find and compare flights from Des Moines to Phoenix that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 2/20

7:17 pm-6:11 pm

1 stop23h 54m

Phoenix Sky Harbor Intl

Wed 2/25

8:04 pm-6:42 pm

2 stops21h 38m

$231

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Mon 2/16

7:17 pm-8:42 am

1 stop14h 25m

Phoenix Sky Harbor Intl

Fri 2/20

5:05 am-7:48 pm

2 stops13h 43m

$232

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 2/20

7:17 pm-6:11 pm

1 stop23h 54m

Phoenix Sky Harbor Intl

Mon 2/23

5:05 am-6:32 pm

2 stops12h 27m

$233

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Mon 2/16

7:17 pm-12:41 am

1 stop6h 24m

Phoenix Sky Harbor Intl

Fri 2/20

6:00 am-6:19 pm

1 stop11h 19m

$234

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 3/6

8:21 pm-8:42 am

1 stop13h 21m

Phoenix Sky Harbor Intl

Sun 3/15

9:24 pm-7:16 pm

1 stop19h 52m

$235

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 2/27

7:59 pm-12:41 am

1 stop5h 42m

Phoenix Sky Harbor Intl

Mon 3/2

6:00 am-6:32 pm

1 stop11h 32m

$236

Des MoinesPhoenix

DSM - AZA

DSMAZA

Des Moines

Wed 4/1

11:15 am-12:23 pm

Nonstop3h 08m

Phoenix-Mesa Gateway

Sun 4/5

10:00 am-3:58 pm

1 stop27h 58m

$237

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 3/17

10:28 am-6:18 pm

1 stop9h 50m

Phoenix Sky Harbor Intl

Tue 3/24

11:55 pm-10:48 am

1 stop8h 53m

$239

Des MoinesPhoenix

DSM - AZA

DSMAZA

Des Moines

Fri 4/17

3:37 pm-4:45 pm

Nonstop3h 08m

Phoenix-Mesa Gateway

Mon 4/20

5:30 pm-10:11 pm

Nonstop2h 41m

$240

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 3/31

6:23 pm-7:35 pm

Nonstop3h 12m

Phoenix Sky Harbor Intl

Sat 4/4

7:02 pm-11:59 pm

Nonstop2h 57m

$244

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Phoenix from

How to get the cheapest flight ticket from Des Moines to Phoenix

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Phoenix?

If you are unable to visit Phoenix during the month of October, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $297.

What is the cheapest day to depart on your flight to Phoenix?

On average, the least expensive day to fly to Phoenix from Des Moines is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $357. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $474.

What is the cheapest time of day to depart on your flight to Phoenix?

The cheapest time of day to fly to Phoenix is in the evening when flights can be purchased for as low as $164. In the morning is when there is more demand to fly to Phoenix, so prices are often more expensive at around $395 per ticket.

What is the cheapest Des Moines to Phoenix flight route?

Fly from Des Moines to Phoenix-Mesa Gateway for the best Des Moines - Phoenix flight prices

How far in advance should I book a flight to Phoenix?

You are more likely to see cheaper flights to Phoenix from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Phoenix for around $329 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Phoenix from Des Moines for as low as $272 on momondo.

What cabin class options are available on Des Moines to Phoenix flights?

There are 3 cabin classes available to choose from on Des Moines to Phoenix flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Des Moines to Phoenix flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Phoenix

Fastest flight time

2h 55m

Direct flights

Every day

Airports in Phoenix

3 airports
The fastest flight from Des Moines to Phoenix takes 2h 55m
Direct flights go from Des Moines to Phoenix every day.
There are 3 airports in Phoenix. From Des Moines there are direct flights to Phoenix Sky Harbor Intl (PHX), Phoenix-Mesa Gateway (AZA).
Search flight deals

  • How far is Des Moines to Phoenix by plane?

    A flight from Des Moines to Phoenix will travel around 1152.4 mi. A reasonable flight in good conditions will take 2h 55m.

  • When did momondo last update prices for flights from Des Moines Airport to Phoenix?

    Prices for flights from Des Moines Airport to Phoenix were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Phoenix?

  • How old do you have to be to fly from Des Moines Airport to Phoenix?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Phoenix.

  • What documentation or ID do you need to fly to Phoenix?

    The necessary travel and health documents for your Phoenix trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Phoenix

Compare and see reviews for airlines that fly from Des Moines to Phoenix with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $112Free CancellationRating
7.2
705 reviews
Search Allegiant Air flights
FrontierPriceFrom $125Free CancellationRating
5.7
3,058 reviews
Search Frontier flights
SouthwestPriceFrom $187Free CancellationRating
8.0
4,268 reviews
Search Southwest flights
American AirlinesPriceFrom $190Free CancellationRating
7.2
11,193 reviews
Search American Airlines flights
United AirlinesPriceFrom $213Free CancellationRating
7.4
9,193 reviews
Search United Airlines flights
DeltaPriceFrom $216Free CancellationRating
7.9
8,112 reviews
Search Delta flights
JetBluePriceFrom $219Free CancellationRating
7.2
2,895 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Phoenix?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Phoenix from Des Moines.

Can I find flights from Des Moines to Phoenix with flexible booking policies on momondo?

All flight searches from Des Moines to Phoenix on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Phoenix?

Once you have performed a search for Des Moines to Phoenix flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Phoenix right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Phoenix now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Phoenix and let you know when they change.

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Find better results for your trip to the United States

Fly into one of these airports located in Phoenix

Airports listed have a maximum distance of 25.4 mi from Phoenix
Phoenix-Mesa Gateway Airport