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Cheap flights from Des Moines to Orlando from $216

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Orlando departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Orlando

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:15 pm - 10:47 pm
DSM
-
MLB
7h 32m
1 stop
Delta Logo
5:55 am - 10:14 am
MLB
-
DSM
5h 19m
1 stop
$403Delta
Tue, Aug 11 - Sat, Aug 22
American Airlines Logo
7:10 am - 6:37 pm
DSM
-
MLB
10h 27m
2 stops
American Airlines Logo
7:07 pm - 12:10 am
MLB
-
DSM
6h 03m
1 stop
$410American Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
7:10 am - 6:37 pm
DSM
-
MLB
10h 27m
2 stops
American Airlines Logo
6:02 am - 1:21 pm
MLB
-
DSM
8h 19m
2 stops
$415American Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
7:10 am - 10:23 pm
DSM
-
MLB
14h 13m
2 stops
American Airlines Logo
12:02 pm - 5:39 pm
MLB
-
DSM
6h 37m
1 stop
$422American Airlines
Wed, Aug 12 - Sat, Sep 12
American Airlines Logo
7:10 am - 10:23 pm
DSM
-
MLB
14h 13m
2 stops
American Airlines Logo
6:24 am - 1:04 pm
MLB
-
DSM
7h 40m
2 stops
$427American Airlines
Wed, Aug 12 - Sat, Sep 19
Delta Logo
2:15 pm - 10:47 pm
DSM
-
MLB
7h 32m
1 stop
Delta Logo
5:55 am - 10:14 am
MLB
-
DSM
5h 19m
1 stop
$435Delta
Thu, Aug 13 - Wed, Sep 9
American Airlines Logo
1:51 pm - 11:59 pm
DSM
-
MLB
9h 08m
2 stops
American Airlines Logo
7:07 pm - 12:10 am
MLB
-
DSM
6h 03m
1 stop
$440American Airlines
Fri, Jun 5 - Wed, Jun 17
American Airlines Logo
6:00 am - 5:14 pm
DSM
-
MLB
10h 14m
2 stops
American Airlines Logo
6:00 am - 3:12 pm
MLB
-
DSM
10h 12m
2 stops
$445American Airlines
Sat, Aug 29 - Sun, Sep 6
American Airlines Logo
1:04 pm - 12:17 am
DSM
-
MLB
10h 13m
2 stops
American Airlines Logo
5:41 pm - 12:09 am
MLB
-
DSM
7h 28m
1 stop
$450American Airlines
Thu, Jul 23 - Tue, Jul 28
Delta Logo
2:15 pm - 10:47 pm
DSM
-
MLB
7h 32m
1 stop
Delta Logo
6:35 pm - 10:26 pm
MLB
-
DSM
4h 51m
1 stop
$455Delta
Mon, Aug 10 - Sat, Aug 22

American Airlines flights from Des Moines to Melbourne, Florida

Our best American Airlines deals on Des Moines to Melbourne, Florida flight tickets
American Airlines
Jun 16
DSM7:10 amDes Moines
10h 27m
2 stops
MLB6:37 pmMelbourne
Jun 23
MLB7:07 pmMelbourne
6h 03m
1 stop
DSM12:10 amDes Moines
$410
American Airlines
Jun 16
DSM7:10 amDes Moines
10h 27m
2 stops
MLB6:37 pmMelbourne
Jun 23
MLB6:02 amMelbourne
8h 19m
2 stops
DSM1:21 pmDes Moines
$415
American Airlines
Aug 12
DSM7:10 amDes Moines
14h 13m
2 stops
MLB10:23 pmMelbourne
Aug 19
MLB6:25 amMelbourne
6h 59m
1 stop
DSM12:24 pmDes Moines
$422

Delta flights from Des Moines to Melbourne, Florida

Our best Delta deals on Des Moines to Melbourne, Florida flight tickets
Delta
Aug 11
DSM11:04 amDes Moines
5h 58m
1 stop
MLB6:02 pmMelbourne
Sep 12
MLB6:35 pmMelbourne
4h 51m
1 stop
DSM10:26 pmDes Moines
$403
Delta
Aug 13
DSM2:15 pmDes Moines
7h 32m
1 stop
MLB10:47 pmMelbourne
Aug 18
MLB5:55 amMelbourne
5h 19m
1 stop
DSM10:14 amDes Moines
$435
Delta
Aug 10
DSM2:15 pmDes Moines
7h 32m
1 stop
MLB10:47 pmMelbourne
Aug 18
MLB5:55 amMelbourne
5h 19m
1 stop
DSM10:14 amDes Moines
$455

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Melbourne, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Des Moines to Melbourne, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 8/11

2:15 pm-10:47 pm

1 stop7h 32m

Melbourne

Sat 8/22

5:55 am-10:14 am

1 stop5h 19m

$403

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 6/16

7:10 am-6:37 pm

2 stops10h 27m

Melbourne

Tue 6/23

7:07 pm-12:10 am

1 stop6h 03m

$410

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 6/16

7:10 am-6:37 pm

2 stops10h 27m

Melbourne

Tue 6/23

6:02 am-1:21 pm

2 stops8h 19m

$415

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 8/12

7:10 am-10:23 pm

2 stops14h 13m

Melbourne

Sat 9/12

12:02 pm-5:39 pm

1 stop6h 37m

$422

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 8/12

7:10 am-10:23 pm

2 stops14h 13m

Melbourne

Sat 9/19

6:24 am-1:04 pm

2 stops7h 40m

$427

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Thu 8/13

2:15 pm-10:47 pm

1 stop7h 32m

Melbourne

Wed 9/9

5:55 am-10:14 am

1 stop5h 19m

$435

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Fri 6/5

1:51 pm-11:59 pm

2 stops9h 08m

Melbourne

Wed 6/17

7:07 pm-12:10 am

1 stop6h 03m

$440

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 8/29

6:00 am-5:14 pm

2 stops10h 14m

Melbourne

Sun 9/6

6:00 am-3:12 pm

2 stops10h 12m

$445

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Thu 7/23

1:04 pm-12:17 am

2 stops10h 13m

Melbourne

Tue 7/28

5:41 pm-12:09 am

1 stop7h 28m

$450
Quickest round-trip

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Mon 8/10

2:15 pm-10:47 pm

1 stop7h 32m

Melbourne

Sat 8/22

6:35 pm-10:26 pm

1 stop4h 51m

$455

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Melbourne, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Melbourne?

Delta and American Airlines are the most popular carriers operating from Des Moines to Melbourne

What airlines fly to Melbourne, Florida?

American Airlines, Allegiant Air and United Airlines are the top three most popular airlines that fly to Melbourne, Florida from Des Moines according to our data. American Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Melbourne, Florida. Keep in mind that there are 6 different airlines that fly to Melbourne, Florida on a routine basis, so you have a few additional options to choose from.

When to book flights from Des Moines to Melbourne, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Melbourne, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Melbourne, Florida (DSM to MLB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Melbourne, Florida

Fastest flight time

4h 43m

Direct flights

None
The fastest flight from Des Moines to Melbourne, Florida takes 4h 43m
There are no direct flights from Des Moines to Melbourne, Florida. There are no popular flight routes from Des Moines to Melbourne, Florida.
Search flight deals

Frequently asked questions about flying from Des Moines to Melbourne, Florida

  • How far is Des Moines to Melbourne by plane?

    The straight-line distance from Des Moines to Melbourne is 1186.0 mi. Flights usually cover this in 4h 43m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Melbourne Airport?

    Prices for flights from Des Moines Airport to Melbourne Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Melbourne Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Melbourne Airport.

  • What documentation or ID do you need to fly to Melbourne Airport?

    The travel and health documents you'll need for your trip to Melbourne Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Melbourne Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Melbourne?

It is quick and easy to find Des Moines to Melbourne flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Melbourne that suits you.

Can I find flights from Des Moines to Melbourne with flexible booking policies on momondo?

Flights from Des Moines to Melbourne with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Melbourne?

momondo helps you find the best flight between Des Moines and Melbourne by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Melbourne right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Melbourne flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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