Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Orlando from $205

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Orlando departing on 10/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Orlando

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:15 pm - 10:44 pmDSM-MLB
4h 29m1 stop
Delta Logo
5:55 am - 10:23 amMLB-DSM
5h 28m1 stop
$343Delta
Find Deal
Tue, Mar 3 - Wed, Mar 4
Delta Logo
6:20 am - 5:59 pmDSM-MLB
10h 39m2 stops
Delta Logo
5:55 am - 10:23 amMLB-DSM
5h 28m1 stop
$348Delta
Find Deal
Tue, Mar 3 - Wed, Mar 4
Delta Logo
2:16 pm - 10:49 pmDSM-MLB
7h 33m1 stop
Delta Logo
6:47 pm - 10:34 pmMLB-DSM
4h 47m1 stop
$361Delta
Find Deal
Mon, Dec 15 - Wed, Dec 17
Delta Logo
2:59 pm - 10:49 pmDSM-MLB
6h 50m2 stops
Delta Logo
6:00 am - 10:38 amMLB-DSM
5h 38m1 stop
$366Delta
Find Deal
Mon, Dec 15 - Tue, Dec 16
Delta Logo
2:59 pm - 10:49 pmDSM-MLB
6h 50m2 stops
Delta Logo
6:00 am - 4:16 pmMLB-DSM
11h 16m2 stops
$371Delta
Find Deal
Mon, Dec 15 - Tue, Dec 16
Delta Logo
6:20 am - 5:59 pmDSM-MLB
10h 39m2 stops
Delta Logo
6:35 pm - 10:28 pmMLB-DSM
4h 53m1 stop
$376Delta
Find Deal
Wed, Mar 4 - Tue, Mar 10
Delta Logo
5:47 am - 1:45 pmDSM-MLB
6h 58m1 stop
Delta Logo
6:00 am - 10:05 amMLB-DSM
5h 05m1 stop
$399Delta
Find Deal
Wed, Nov 5 - Sat, Nov 8
American Airlines Logo
6:00 am - 4:51 pmDSM-MLB
9h 51m2 stops
American Airlines Logo
6:05 am - 1:31 pmMLB-DSM
8h 26m1 stop
$404American Airlines
Find Deal
Wed, Nov 5 - Sat, Nov 8
Delta Logo
5:15 pm - 10:53 pmDSM-MLB
4h 38m1 stop
Delta Logo
6:00 am - 10:42 amMLB-DSM
5h 42m1 stop
$408Delta
Find Deal
Sat, Nov 8 - Wed, Nov 12
American Airlines Logo
7:08 am - 1:02 pmDSM-MLB
4h 54m1 stop
American Airlines Logo
1:49 pm - 9:56 pmMLB-DSM
9h 07m2 stops
$428American Airlines
Find Deal
Tue, Mar 3 - Wed, Mar 4

Delta flights from Des Moines to Melbourne, Florida

Our best Delta deals on Des Moines to Melbourne, Florida flight tickets
Delta
Mar 3
DSM5:15 pmDes Moines
4h 29m
1 stop
MLB10:44 pmMelbourne
Mar 4
MLB5:55 amMelbourne
5h 28m
1 stop
DSM10:23 amDes Moines
$343
Find similar
Delta
Mar 3
DSM6:20 amDes Moines
10h 39m
2 stops
MLB5:59 pmMelbourne
Mar 4
MLB5:55 amMelbourne
5h 28m
1 stop
DSM10:23 amDes Moines
$348
Find similar
Delta
Dec 15
DSM2:16 pmDes Moines
7h 33m
1 stop
MLB10:49 pmMelbourne
Dec 17
MLB6:47 pmMelbourne
4h 47m
1 stop
DSM10:34 pmDes Moines
$361
Find similar

American Airlines flights from Des Moines to Melbourne, Florida

Our best American Airlines deals on Des Moines to Melbourne, Florida flight tickets
American Airlines
Nov 5
DSM6:00 amDes Moines
9h 51m
2 stops
MLB4:51 pmMelbourne
Nov 8
MLB6:05 amMelbourne
8h 26m
1 stop
DSM1:31 pmDes Moines
$404
Find similar
American Airlines
Nov 5
DSM5:00 amDes Moines
10h 51m
2 stops
MLB4:51 pmMelbourne
Nov 8
MLB6:05 amMelbourne
9h 51m
2 stops
DSM2:56 pmDes Moines
$409
Find similar
American Airlines
Mar 3
DSM7:08 amDes Moines
4h 54m
1 stop
MLB1:02 pmMelbourne
Mar 4
MLB1:49 pmMelbourne
9h 07m
2 stops
DSM9:56 pmDes Moines
$428
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Melbourne, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Des Moines to Melbourne, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 3/3

5:15 pm-10:44 pm

1 stop4h 29m

Melbourne

Wed 3/4

5:55 am-10:23 am

1 stop5h 28m

$343

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 3/3

6:20 am-5:59 pm

2 stops10h 39m

Melbourne

Wed 3/4

5:55 am-10:23 am

1 stop5h 28m

$348

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Mon 12/15

2:16 pm-10:49 pm

1 stop7h 33m

Melbourne

Wed 12/17

6:47 pm-10:34 pm

1 stop4h 47m

$361

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Mon 12/15

2:59 pm-10:49 pm

2 stops6h 50m

Melbourne

Tue 12/16

6:00 am-10:38 am

1 stop5h 38m

$366

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Mon 12/15

2:59 pm-10:49 pm

2 stops6h 50m

Melbourne

Tue 12/16

6:00 am-4:16 pm

2 stops11h 16m

$371

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 3/4

6:20 am-5:59 pm

2 stops10h 39m

Melbourne

Tue 3/10

6:35 pm-10:28 pm

1 stop4h 53m

$376

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 11/5

5:47 am-1:45 pm

1 stop6h 58m

Melbourne

Sat 11/8

6:00 am-10:05 am

1 stop5h 05m

$399

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 11/5

6:00 am-4:51 pm

2 stops9h 51m

Melbourne

Sat 11/8

6:05 am-1:31 pm

1 stop8h 26m

$404

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 11/8

5:15 pm-10:53 pm

1 stop4h 38m

Melbourne

Wed 11/12

6:00 am-10:42 am

1 stop5h 42m

$408

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 3/3

7:08 am-1:02 pm

1 stop4h 54m

Melbourne

Wed 3/4

1:49 pm-9:56 pm

2 stops9h 07m

$428

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

See travel insights to Orlando from

How to get the cheapest flight ticket from Des Moines to Melbourne, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Melbourne, Florida?

The cheapest day to depart on your flight to Melbourne, Florida is on a Tuesday when prices can be found for as low as $352. This is often the case because there is less demand to fly during this day of the week. On the other hand, Friday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $663.

What is the cheapest time of day to depart on your flight to Melbourne, Florida?

According to our data, the cheapest time of day to fly to Melbourne, Florida is at noon. momondo users have found flights departing from Des Moines to Melbourne, Florida at noon for as low as $388. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $472.

When to book flights from Des Moines to Melbourne, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Melbourne, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Melbourne, Florida (DSM to MLB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Melbourne, Florida

Direct flights

None
There are no direct flights from Des Moines to Melbourne, Florida. There are no popular flight routes from Des Moines to Melbourne, Florida.
Search flight deals

  • How far is Des Moines to Melbourne by plane?

    The straight-line distance from Des Moines to Melbourne is 1186.0 mi. Flights usually cover this in 4h 29m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Melbourne Airport?

    Prices for flights from Des Moines Airport to Melbourne Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Melbourne Airport?

  • How old do you have to be to fly from Des Moines Airport to Melbourne Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Melbourne Airport.

  • What documentation or ID do you need to fly to Melbourne Airport?

    The travel and health documents you'll need for your trip to Melbourne Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Melbourne Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Melbourne, Florida?

Best airlines flying from Des Moines to Melbourne, Florida

Compare and see reviews for airlines that fly from Des Moines to Melbourne, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $330Free CancellationRating
7.9
7,982 reviews
Search Delta flights
American AirlinesPriceFrom $406Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Melbourne?

It is quick and easy to find Des Moines to Melbourne flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Melbourne that suits you.

Can I find flights from Des Moines to Melbourne with flexible booking policies on momondo?

Flights from Des Moines to Melbourne with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Melbourne?

momondo helps you find the best flight between Des Moines and Melbourne by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Melbourne right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Melbourne flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Melbourne, Florida trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 11/22
Sat 11/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States