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Cheap flights from Des Moines to Orlando from $200

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Orlando departing on 2/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Orlando

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:25 pm - 9:45 pm
DSM
-
MLB
8h 20m2 stops
Delta Logo
6:00 am - 10:41 am
MLB
-
DSM
5h 41m1 stop
$331Delta
Sat, Jan 17 - Fri, Jan 23
Delta Logo
5:16 pm - 10:40 pm
DSM
-
MLB
4h 24m1 stop
Delta Logo
6:00 am - 10:41 am
MLB
-
DSM
5h 41m1 stop
$335Delta
Tue, Jan 13 - Fri, Jan 23
Delta Logo
6:24 am - 5:49 pm
DSM
-
MLB
10h 25m2 stops
Delta Logo
6:00 am - 10:41 am
MLB
-
DSM
5h 41m1 stop
$340Delta
Tue, Jan 13 - Fri, Jan 23
American Airlines Logo
5:00 pm - 11:58 pm
DSM
-
MLB
5h 58m1 stop
American Airlines Logo
6:20 am - 1:17 pm
MLB
-
DSM
7h 57m1 stop
$358American Airlines
Sat, Feb 7 - Sat, Feb 14
Delta Logo
12:25 pm - 9:45 pm
DSM
-
MLB
8h 20m2 stops
Delta Logo
6:00 am - 12:14 pm
MLB
-
DSM
7h 14m1 stop
$363Delta
Sat, Feb 7 - Sat, Feb 14
Delta Logo
5:16 pm - 10:40 pm
DSM
-
MLB
4h 24m1 stop
Delta Logo
6:00 am - 10:41 am
MLB
-
DSM
5h 41m1 stop
$381Delta
Fri, Jan 16 - Thu, Jan 22
American Airlines Logo
7:40 am - 3:51 pm
DSM
-
MLB
7h 11m1 stop
American Airlines Logo
6:20 am - 1:17 pm
MLB
-
DSM
7h 57m1 stop
$384American Airlines
Sat, Jan 31 - Sat, Feb 21
American Airlines Logo
1:16 pm - 11:58 pm
DSM
-
MLB
9h 42m2 stops
American Airlines Logo
6:20 am - 1:17 pm
MLB
-
DSM
7h 57m1 stop
$389American Airlines
Sat, Jan 31 - Sat, Feb 21
American Airlines Logo
11:35 am - 11:58 pm
DSM
-
MLB
11h 23m2 stops
American Airlines Logo
6:20 am - 5:51 pm
MLB
-
DSM
12h 31m2 stops
$394American Airlines
Sat, Feb 7 - Sat, Feb 14
Delta Logo
12:04 pm - 10:40 pm
DSM
-
MLB
9h 36m2 stops
Delta Logo
6:00 am - 10:41 am
MLB
-
DSM
5h 41m1 stop
$396Delta
Wed, Jan 14 - Fri, Jan 23

American Airlines flights from Des Moines to Melbourne, Florida

Our best American Airlines deals on Des Moines to Melbourne, Florida flight tickets
American Airlines
Feb 7
DSM5:00 pmDes Moines
5h 58m
1 stop
MLB11:58 pmMelbourne
Feb 14
MLB6:20 amMelbourne
7h 57m
1 stop
DSM1:17 pmDes Moines
$358
Find similar
American Airlines
Jan 31
DSM7:40 amDes Moines
7h 11m
1 stop
MLB3:51 pmMelbourne
Feb 21
MLB6:20 amMelbourne
7h 57m
1 stop
DSM1:17 pmDes Moines
$384
Find similar
American Airlines
Jan 31
DSM1:16 pmDes Moines
9h 42m
2 stops
MLB11:58 pmMelbourne
Feb 21
MLB6:20 amMelbourne
7h 57m
1 stop
DSM1:17 pmDes Moines
$389
Find similar

Delta flights from Des Moines to Melbourne, Florida

Our best Delta deals on Des Moines to Melbourne, Florida flight tickets
Delta
Jan 17
DSM12:25 pmDes Moines
8h 20m
2 stops
MLB9:45 pmMelbourne
Jan 23
MLB6:00 amMelbourne
5h 41m
1 stop
DSM10:41 amDes Moines
$331
Find similar
Delta
Jan 13
DSM5:16 pmDes Moines
4h 24m
1 stop
MLB10:40 pmMelbourne
Jan 23
MLB6:00 amMelbourne
5h 41m
1 stop
DSM10:41 amDes Moines
$335
Find similar
Delta
Jan 13
DSM6:24 amDes Moines
10h 25m
2 stops
MLB5:49 pmMelbourne
Jan 23
MLB6:00 amMelbourne
5h 41m
1 stop
DSM10:41 amDes Moines
$340
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Melbourne, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Des Moines to Melbourne, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 1/17

12:25 pm-9:45 pm

2 stops8h 20m

Melbourne

Fri 1/23

6:00 am-10:41 am

1 stop5h 41m

$331

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 1/13

5:16 pm-10:40 pm

1 stop4h 24m

Melbourne

Fri 1/23

6:00 am-10:41 am

1 stop5h 41m

$335

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 1/13

6:24 am-5:49 pm

2 stops10h 25m

Melbourne

Fri 1/23

6:00 am-10:41 am

1 stop5h 41m

$340

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 2/7

5:00 pm-11:58 pm

1 stop5h 58m

Melbourne

Sat 2/14

6:20 am-1:17 pm

1 stop7h 57m

$358

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 2/7

12:25 pm-9:45 pm

2 stops8h 20m

Melbourne

Sat 2/14

6:00 am-12:14 pm

1 stop7h 14m

$363

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Fri 1/16

5:16 pm-10:40 pm

1 stop4h 24m

Melbourne

Thu 1/22

6:00 am-10:41 am

1 stop5h 41m

$381

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 1/31

7:40 am-3:51 pm

1 stop7h 11m

Melbourne

Sat 2/21

6:20 am-1:17 pm

1 stop7h 57m

$384

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 1/31

1:16 pm-11:58 pm

2 stops9h 42m

Melbourne

Sat 2/21

6:20 am-1:17 pm

1 stop7h 57m

$389

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 2/7

11:35 am-11:58 pm

2 stops11h 23m

Melbourne

Sat 2/14

6:20 am-5:51 pm

2 stops12h 31m

$394

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 1/14

12:04 pm-10:40 pm

2 stops9h 36m

Melbourne

Fri 1/23

6:00 am-10:41 am

1 stop5h 41m

$396

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Melbourne, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Melbourne, Florida?

The cheapest day to depart on your flight to Melbourne, Florida is on a Tuesday when prices can be found for as low as $352. This is often the case because there is less demand to fly during this day of the week. On the other hand, Friday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $663.

What is the cheapest time of day to depart on your flight to Melbourne, Florida?

According to our data, the cheapest time of day to fly to Melbourne, Florida is at noon. momondo users have found flights departing from Des Moines to Melbourne, Florida at noon for as low as $388. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $472.

When to book flights from Des Moines to Melbourne, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Melbourne, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Melbourne, Florida (DSM to MLB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Melbourne, Florida

Fastest flight time

4h 24m

Direct flights

None
The fastest flight from Des Moines to Melbourne, Florida takes 4h 24m
There are no direct flights from Des Moines to Melbourne, Florida. There are no popular flight routes from Des Moines to Melbourne, Florida.
Search flight deals

  • How far is Des Moines to Melbourne by plane?

    The straight-line distance from Des Moines to Melbourne is 1186.0 mi. Flights usually cover this in 4h 24m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Melbourne Airport?

    Prices for flights from Des Moines Airport to Melbourne Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Melbourne Airport?

  • How old do you have to be to fly from Des Moines Airport to Melbourne Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Melbourne Airport.

  • What documentation or ID do you need to fly to Melbourne Airport?

    The travel and health documents you'll need for your trip to Melbourne Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Melbourne Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Melbourne, Florida?

Best airlines flying from Des Moines to Melbourne, Florida

Compare and see reviews for airlines that fly from Des Moines to Melbourne, Florida with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $406Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Melbourne?

It is quick and easy to find Des Moines to Melbourne flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Melbourne that suits you.

Can I find flights from Des Moines to Melbourne with flexible booking policies on momondo?

Flights from Des Moines to Melbourne with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Melbourne?

momondo helps you find the best flight between Des Moines and Melbourne by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Melbourne right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Melbourne flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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