Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Louisiana from $159

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Louisiana departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Louisiana

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:59 pm - 8:19 am
DSM
-
MSY
16h 20m
1 stop
Multiple Airlines Logo
3:36 pm - 7:16 pm
MSY
-
DSM
27h 40m
1 stop
$239Multiple Airlines
Sun, Mar 22 - Fri, Mar 27
Multiple Airlines Logo
8:38 pm - 11:01 am
DSM
-
MSY
14h 23m
2 stops
Multiple Airlines Logo
2:34 pm - 7:04 pm
MSY
-
DSM
28h 30m
1 stop
$283Multiple Airlines
Mon, Feb 23 - Thu, Feb 26
American Airlines Logo
10:04 am - 2:37 pm
DSM
-
MSY
4h 33m
1 stop
American Airlines Logo
6:23 am - 6:19 pm
MSY
-
DSM
11h 56m
1 stop
$293American Airlines
Wed, Mar 4 - Sat, Mar 7
Multiple Airlines Logo
8:21 pm - 9:38 am
DSM
-
MSY
37h 17m
2 stops
Multiple Airlines Logo
7:10 pm - 12:33 pm
MSY
-
DSM
17h 23m
1 stop
$300Multiple Airlines
Mon, Mar 9 - Mon, Mar 16
Multiple Airlines Logo
3:39 pm - 5:24 am
DSM
-
MSY
13h 45m
1 stop
Multiple Airlines Logo
2:34 pm - 7:04 pm
MSY
-
DSM
28h 30m
1 stop
$302Multiple Airlines
Mon, Feb 23 - Thu, Feb 26
American Airlines Logo
2:00 pm - 7:26 pm
DSM
-
BTR
5h 26m
1 stop
American Airlines Logo
5:00 am - 10:34 am
BTR
-
DSM
5h 34m
1 stop
$304American Airlines
Tue, Mar 10 - Sun, Mar 15
Frontier Logo
7:27 pm - 2:18 pm
DSM
-
MSY
18h 51m
1 stop
Frontier Logo
3:13 pm - 6:50 pm
MSY
-
DSM
27h 37m
1 stop
$306Frontier
Sun, Feb 15 - Sat, Feb 21
Delta Logo
11:33 am - 4:13 pm
DSM
-
AEX
4h 40m
1 stop
Delta Logo
5:00 pm - 10:38 pm
AEX
-
DSM
5h 38m
1 stop
$308Delta
Tue, Mar 24 - Tue, Mar 31
Delta Logo
10:28 am - 9:37 pm
DSM
-
AEX
11h 09m
2 stops
Delta Logo
11:43 am - 4:33 pm
AEX
-
DSM
4h 50m
1 stop
$314Delta
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
2:59 pm - 9:19 pm
DSM
-
MSY
6h 20m
1 stop
United Airlines Logo
7:00 am - 2:24 pm
MSY
-
DSM
7h 24m
1 stop
$323United Airlines
Mon, Mar 9 - Mon, Mar 16

American Airlines flights from Des Moines to Louisiana

Our best American Airlines deals on Des Moines to Louisiana flight tickets
American Airlines
Mar 4
DSM10:04 amDes Moines
4h 33m
1 stop
MSY2:37 pmNew Orleans Louis Armstrong
Mar 7
MSY6:23 amNew Orleans Louis Armstrong
11h 56m
1 stop
DSM6:19 pmDes Moines
$293
American Airlines
Mar 10
DSM2:00 pmDes Moines
5h 26m
1 stop
BTR7:26 pmBaton Rouge Ryan
Mar 15
BTR5:00 amBaton Rouge Ryan
5h 34m
1 stop
DSM10:34 amDes Moines
$304
American Airlines
Mar 10
DSM5:00 amDes Moines
7h 51m
2 stops
BTR12:51 pmBaton Rouge Ryan
Mar 15
BTR5:00 amBaton Rouge Ryan
5h 34m
1 stop
DSM10:34 amDes Moines
$309

United Airlines flights from Des Moines to Louisiana

Our best United Airlines deals on Des Moines to Louisiana flight tickets
United Airlines
Mar 25
DSM3:28 pmDes Moines
8h 00m
2 stops
MSY11:28 pmNew Orleans Louis Armstrong
Mar 28
MSY7:00 amNew Orleans Louis Armstrong
6h 23m
1 stop
DSM1:23 pmDes Moines
$328
United Airlines
Apr 2
DSM1:41 pmDes Moines
8h 04m
1 stop
MSY9:45 pmNew Orleans Louis Armstrong
Apr 6
MSY5:25 pmNew Orleans Louis Armstrong
5h 18m
1 stop
DSM10:43 pmDes Moines
$375
United Airlines
Feb 23
DSM3:24 pmDes Moines
8h 04m
2 stops
MSY11:28 pmNew Orleans Louis Armstrong
Feb 27
MSY12:48 pmNew Orleans Louis Armstrong
8h 53m
2 stops
DSM9:41 pmDes Moines
$477

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sun 3/22

3:59 pm-8:19 am

1 stop16h 20m

New Orleans Louis Armstrong

Fri 3/27

3:36 pm-7:16 pm

1 stop27h 40m

$239

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 2/23

8:38 pm-11:01 am

2 stops14h 23m

New Orleans Louis Armstrong

Thu 2/26

2:34 pm-7:04 pm

1 stop28h 30m

$283

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Wed 3/4

10:04 am-2:37 pm

1 stop4h 33m

New Orleans Louis Armstrong

Sat 3/7

6:23 am-6:19 pm

1 stop11h 56m

$293

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 3/9

8:21 pm-9:38 am

2 stops37h 17m

New Orleans Louis Armstrong

Mon 3/16

7:10 pm-12:33 pm

1 stop17h 23m

$300

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 2/23

3:39 pm-5:24 am

1 stop13h 45m

New Orleans Louis Armstrong

Thu 2/26

2:34 pm-7:04 pm

1 stop28h 30m

$302

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Tue 3/10

2:00 pm-7:26 pm

1 stop5h 26m

Baton Rouge Ryan

Sun 3/15

5:00 am-10:34 am

1 stop5h 34m

$304

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Sun 2/15

7:27 pm-2:18 pm

1 stop18h 51m

New Orleans Louis Armstrong

Sat 2/21

3:13 pm-6:50 pm

1 stop27h 37m

$306

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Tue 3/24

11:33 am-4:13 pm

1 stop4h 40m

Alexandria

Tue 3/31

5:00 pm-10:38 pm

1 stop5h 38m

$308

Des MoinesAlexandria

DSM - AEX

DSMAEX

Des Moines

Tue 3/24

10:28 am-9:37 pm

2 stops11h 09m

Alexandria

Tue 3/31

11:43 am-4:33 pm

1 stop4h 50m

$314

Des MoinesNew Orleans

DSM - MSY

DSMMSY

Des Moines

Mon 3/9

2:59 pm-9:19 pm

1 stop6h 20m

New Orleans Louis Armstrong

Mon 3/16

7:00 am-2:24 pm

1 stop7h 24m

$323

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Louisiana from

How to get the cheapest flight ticket from Des Moines to Louisiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisiana?

In general, November is the cheapest month to fly from Des Moines to Louisiana. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. The month of September is another great option to travel to Louisiana, with average flight prices from Des Moines averaging around $367.

How far in advance should I book a flight to Louisiana?

You are more likely to see cheaper flights to Louisiana from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Louisiana for around $407 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Louisiana from Des Moines for as low as $288 on momondo.

Cheap Des Moines to Louisiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Louisiana

Fastest flight time

4h 29m

Direct flights

None
The fastest flight from Des Moines to Louisiana takes 4h 29m
There are no direct flights from Des Moines to Louisiana. There are no popular flight routes from Des Moines to Louisiana.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Louisiana?

    Prices for flights from Des Moines Airport to Louisiana refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Louisiana?

  • How old do you have to be to fly from Des Moines Airport to Louisiana?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Louisiana.

  • What documentation or ID do you need to fly to Louisiana?

    The necessary travel and health documents for your Louisiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Louisiana

Compare and see reviews for airlines that fly from Des Moines to Louisiana with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $236Free CancellationRating
7.2
11,258 reviews
Search American Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,174 reviews
Search Delta flights
SouthwestPriceFrom $270Free CancellationRating
8.0
4,282 reviews
Search Southwest flights
United AirlinesPriceFrom $312Free CancellationRating
7.4
9,259 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Louisiana?

Finding the right flight to Louisiana from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Louisiana quick and easy, saving you time and money.

Can I find flights from Des Moines to Louisiana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Louisiana from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Louisiana?

Once you have performed a search for Des Moines to Louisiana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Louisiana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Louisiana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisiana and let you know when they change.

An easier way to manage your Louisiana trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 3/11
Wed 3/18
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Louisiana

Popular cities in Louisiana

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $49
Flights to Los Angelesfrom $49
Flights to Miamifrom $36
Flights to Chicagofrom $50
Flights to Orlandofrom $27
Flights to San Franciscofrom $51
Flights to Las Vegasfrom $28
Flights to Washington, D.C.from $51
Flights to Bostonfrom $50
Flights to Atlantafrom $49
Flights to Dallasfrom $50
Flights to Seattlefrom $65