Cheap flights from Columbus, Mississippi to San Francisco from $421

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus, Mississippi to San Francisco departing on 2/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:03 pm - 11:12 pm
GTR
-
SFO
9h 09m1 stop
American Airlines Logo
7:00 am - 3:32 pm
SFO
-
GTR
6h 32m1 stop
$421American Airlines
Wed, Feb 4 - Sun, Feb 8
American Airlines Logo
4:03 pm - 9:37 pm
GTR
-
SFO
7h 34m1 stop
American Airlines Logo
7:01 pm - 3:32 pm
SFO
-
GTR
18h 31m2 stops
$488American Airlines
Wed, Feb 4 - Sun, Feb 8
Delta Logo
6:07 am - 12:52 pm
GTR
-
SFO
8h 45m1 stop
Delta Logo
11:46 am - 8:25 pm
SFO
-
GTR
6h 39m1 stop
$602Delta
Sun, Dec 21 - Tue, Jan 13
American Airlines Logo
4:03 pm - 10:05 am
GTR
-
SFO
20h 02m2 stops
American Airlines Logo
7:01 pm - 3:32 pm
SFO
-
GTR
18h 31m2 stops
$663American Airlines
Wed, Feb 4 - Sun, Feb 8
American Airlines Logo
3:46 pm - 10:58 pm
GTR
-
SFO
9h 12m2 stops
American Airlines Logo
6:00 am - 3:32 pm
SFO
-
GTR
7h 32m1 stop
$752American Airlines
Sun, Dec 21 - Tue, Jan 13
American Airlines Logo
3:46 pm - 10:58 pm
GTR
-
SFO
9h 12m2 stops
American Airlines Logo
10:30 pm - 3:32 pm
SFO
-
GTR
15h 02m2 stops
$1,026American Airlines
Sun, Dec 21 - Tue, Jan 13

American Airlines flights from Columbus, Mississippi to San Francisco

Our best American Airlines deals on Columbus, Mississippi to San Francisco flight tickets
American Airlines
Feb 4
GTR4:03 pmColumbus Golden Triangle Reg.
9h 09m
1 stop
SFO11:12 pmSan Francisco
Feb 8
SFO7:00 amSan Francisco
6h 32m
1 stop
GTR3:32 pmColumbus Golden Triangle Reg.
American Airlines
Feb 4
GTR4:03 pmColumbus Golden Triangle Reg.
7h 34m
1 stop
SFO9:37 pmSan Francisco
Feb 8
SFO7:01 pmSan Francisco
18h 31m
2 stops
GTR3:32 pmColumbus Golden Triangle Reg.
American Airlines
Feb 4
GTR4:03 pmColumbus Golden Triangle Reg.
20h 02m
2 stops
SFO10:05 amSan Francisco
Feb 8
SFO7:01 pmSan Francisco
18h 31m
2 stops
GTR3:32 pmColumbus Golden Triangle Reg.

momondo Fare Finder

 
Customize your flight search to find flights from Columbus, Mississippi to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Columbus, Mississippi to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusSan Francisco

GTR - SFO

GTRSFO

Columbus Golden Triangle Reg.

Wed 2/4

4:03 pm-11:12 pm

1 stop9h 09m

San Francisco

Sun 2/8

7:00 am-3:32 pm

1 stop6h 32m

$421

ColumbusSan Francisco

GTR - SFO

GTRSFO

Columbus Golden Triangle Reg.

Wed 2/4

4:03 pm-9:37 pm

1 stop7h 34m

San Francisco

Sun 2/8

7:01 pm-3:32 pm

2 stops18h 31m

$488

ColumbusSan Francisco

GTR - SFO

GTRSFO

Columbus Golden Triangle Reg.

Sun 12/21

6:07 am-12:52 pm

1 stop8h 45m

San Francisco

Tue 1/13

11:46 am-8:25 pm

1 stop6h 39m

$602

ColumbusSan Francisco

GTR - SFO

GTRSFO

Columbus Golden Triangle Reg.

Wed 2/4

4:03 pm-10:05 am

2 stops20h 02m

San Francisco

Sun 2/8

7:01 pm-3:32 pm

2 stops18h 31m

$663

ColumbusSan Francisco

GTR - SFO

GTRSFO

Columbus Golden Triangle Reg.

Sun 12/21

3:46 pm-10:58 pm

2 stops9h 12m

San Francisco

Tue 1/13

6:00 am-3:32 pm

1 stop7h 32m

$752

ColumbusSan Francisco

GTR - SFO

GTRSFO

Columbus Golden Triangle Reg.

Sun 12/21

3:46 pm-10:58 pm

2 stops9h 12m

San Francisco

Tue 1/13

10:30 pm-3:32 pm

2 stops15h 02m

$1,026

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Francisco from

How to get the cheapest flight ticket from Columbus, Mississippi to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to San Francisco?

American Airlines, Southwest and Delta are the top three most popular airlines that fly to San Francisco from Columbus, Mississippi according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 4 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

When to book flights from Columbus, Mississippi to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Columbus, Mississippi to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbus, Mississippi to San Francisco (GTR to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus, Mississippi to San Francisco

Fastest flight time

8h 45m

Direct flights

None
The fastest flight from Columbus, Mississippi to San Francisco takes 8h 45m
There are no direct flights from Columbus, Mississippi to San Francisco. There are no popular flight routes from Columbus, Mississippi to San Francisco.
  • How far is Columbus Golden Triangle Reg. to San Francisco by plane?

    Columbus Golden Triangle Reg. and San Francisco are 1919.1 mi apart from one another. A reasonable flight in good conditions will take 8h 45m.

  • When did momondo last update prices for flights from Columbus Golden Triangle Reg. Airport to San Francisco Airport?

    Prices for flights from Columbus Golden Triangle Reg. Airport to San Francisco Airport were last updated today.

  • How old do you have to be to fly from Columbus Golden Triangle Reg. Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Golden Triangle Reg. Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Big Sur
Calistoga
Santa Clara
Walnut Creek
Berkeley
Daly City
Fremont
Half Moon Bay
Vallejo
Salinas
Livermore
Turlock
Sunnyvale

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to San Francisco?

It is quick and easy to find Columbus to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from Columbus to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Columbus with this policy.

How can momondo help me find flights from Columbus to San Francisco?

momondo helps you find the best flight between Columbus and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Columbus to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Columbus. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Sat 1/10
Sat 1/17

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