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Cheap flights from the Cayman Islands to San Francisco from $356

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the Cayman Islands to San Francisco departing on 8/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from the Cayman Islands to San Francisco

Recent round-trip flight deals from the Cayman Islands to San Francisco

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:30 am - 5:09 pm
GCM
-
SFO
10h 39m
1 stop
Multiple Airlines Logo
10:35 pm - 11:35 am
SFO
-
GCM
35h 00m
2 stops
$718Multiple Airlines
Sat, Aug 15 - Sat, Aug 22
Delta Logo
1:04 pm - 10:00 pm
GCM
-
SFO
10h 56m
1 stop
Delta Logo
10:00 pm - 11:39 am
SFO
-
GCM
11h 39m
1 stop
$772Delta
Thu, Aug 13 - Sat, Sep 5
American Airlines Logo
3:17 pm - 11:10 pm
GCM
-
SFO
9h 53m
1 stop
American Airlines Logo
11:40 pm - 11:30 am
SFO
-
GCM
9h 50m
1 stop
$781American Airlines
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
2:10 pm - 12:54 am
GCM
-
SFO
12h 44m
1 stop
American Airlines Logo
3:46 pm - 11:00 am
SFO
-
GCM
17h 14m
2 stops
$786American Airlines
Thu, Aug 13 - Sat, Sep 5

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American Airlines flights from Cayman Islands to San Francisco

Our best American Airlines deals on Cayman Islands to San Francisco flight tickets
American Airlines
Aug 15
GCM3:17 pmGeorge Town Owen Roberts Intl
9h 53m
1 stop
SFO11:10 pmSan Francisco
Aug 22
SFO11:40 pmSan Francisco
9h 50m
1 stop
GCM11:30 amGeorge Town Owen Roberts Intl
$781
American Airlines
Aug 13
GCM2:10 pmGeorge Town Owen Roberts Intl
12h 44m
1 stop
SFO12:54 amSan Francisco
Sep 5
SFO3:46 pmSan Francisco
17h 14m
2 stops
GCM11:00 amGeorge Town Owen Roberts Intl
$786

momondo Fare Finder

 
Customize your flight search to find flights from Cayman Islands to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from the Cayman Islands to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 8/15

8:30 am-5:09 pm

1 stop10h 39m

San Francisco

Sat 8/22

10:35 pm-11:35 am

2 stops35h 00m

$718

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 8/13

1:04 pm-10:00 pm

1 stop10h 56m

San Francisco

Sat 9/5

10:00 pm-11:39 am

1 stop11h 39m

$772
Quickest round-trip

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 8/15

3:17 pm-11:10 pm

1 stop9h 53m

San Francisco

Sat 8/22

11:40 pm-11:30 am

1 stop9h 50m

$781

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 8/13

2:10 pm-12:54 am

1 stop12h 44m

San Francisco

Sat 9/5

3:46 pm-11:00 am

2 stops17h 14m

$786
Cheapest one-way

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 8/13

4:45 pm-7:13 pm

2 stops28h 28m

$356

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Mon 7/20

4:45 pm-10:30 am

2 stops19h 45m

$364

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Mon 7/20

4:45 pm-10:30 am

2 stops19h 45m

$365

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Mon 7/20

4:45 pm-8:45 pm

3 stops30h 00m

$418

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Mon 7/20

4:45 pm-4:11 pm

3 stops25h 26m

$477

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 8/1

4:45 pm-9:25 am

1 stop18h 40m

$483

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Cayman Islands to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Cayman Islands to San Francisco flights?

You could potentially save up to 38% on your flight if you consider stops on a Cayman Islands to San Francisco flight.

Cheap Cayman Islands to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cayman Islands to San Francisco

Fastest flight time

10h 56m

Direct flights

None
The fastest flight from Cayman Islands to San Francisco takes 10h 56m
There are no direct flights from Cayman Islands to San Francisco. There are no popular flight routes from Cayman Islands to San Francisco.
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Frequently asked questions about flying from the Cayman Islands to San Francisco

  • When did momondo last update prices for flights from Cayman Islands to San Francisco Airport?

    Prices for flights from Cayman Islands to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Cayman Islands to San Francisco Airport?

  • How old do you have to be to fly from Cayman Islands to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cayman Islands to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Cayman Islands to San Francisco

Compare and see reviews for airlines that fly from Cayman Islands to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $709Free CancellationRating
7.1
11,767 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Bodega Bay
South San Francisco
Sonoma
Fremont
Hayward
Roseville
Walnut Creek
Santa Clara
Berkeley
Vallejo
Salinas
Sunnyvale
Big Sur
Burlingame
Daly City
Milpitas
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Cayman Islands to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Cayman Islands.

Can I find flights from Cayman Islands to San Francisco with flexible booking policies on momondo?

Flights from Cayman Islands to San Francisco with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Cayman Islands to San Francisco?

momondo helps you find the best flight between Cayman Islands and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Cayman Islands to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Cayman Islands and alert you when they change.

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