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Cheap flights from the Cayman Islands to San Francisco from $316

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the Cayman Islands to San Francisco departing on 7/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from the Cayman Islands to San Francisco

Recent round-trip flight deals from the Cayman Islands to San Francisco

Enter your travel dates to find the best prices.
Southwest Logo
12:45 pm - 11:30 pm
GCM
-
SFO
12h 45m
2 stops
Southwest Logo
10:50 pm - 11:50 am
SFO
-
GCM
11h 00m
2 stops
$710Southwest
Sun, Jul 12 - Sun, Jul 26
Multiple Airlines Logo
3:50 pm - 9:21 am
GCM
-
SFO
19h 31m
1 stop
Multiple Airlines Logo
8:45 pm - 4:00 pm
SFO
-
GCM
17h 15m
1 stop
$716Multiple Airlines
Sat, Apr 25 - Sat, May 2
Air Canada Logo
12:25 pm - 9:28 am
GCM
-
SFO
23h 03m
2 stops
Air Canada Logo
7:35 pm - 11:30 am
SFO
-
GCM
37h 55m
2 stops
$729Air Canada
Thu, Aug 27 - Tue, Sep 22
Air Canada Logo
10:55 am - 11:25 am
GCM
-
SFO
26h 30m
2 stops
Air Canada Logo
4:30 pm - 11:25 am
SFO
-
GCM
16h 55m
1 stop
$741Air Canada
Sat, Jun 13 - Wed, Jun 17
Air Canada Logo
10:55 am - 9:10 pm
GCM
-
SFO
12h 15m
1 stop
Air Canada Logo
4:30 pm - 11:25 am
SFO
-
GCM
16h 55m
1 stop
$745Air Canada
Sat, Jun 13 - Wed, Jun 17
Air Canada Logo
12:25 pm - 3:27 pm
GCM
-
SFO
29h 02m
1 stop
Air Canada Logo
11:10 am - 11:30 am
SFO
-
GCM
46h 20m
2 stops
$747Air Canada
Thu, Aug 27 - Tue, Sep 22
Air Canada Logo
10:55 am - 11:25 am
GCM
-
SFO
26h 30m
2 stops
Air Canada Logo
4:30 pm - 11:25 am
SFO
-
GCM
16h 55m
1 stop
$748Air Canada
Sat, Jun 13 - Wed, Jun 17
Multiple Airlines Logo
8:50 am - 12:17 pm
GCM
-
SFO
53h 27m
2 stops
Multiple Airlines Logo
6:29 pm - 4:00 pm
SFO
-
GCM
19h 31m
1 stop
$784Multiple Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
11:56 am - 11:59 pm
GCM
-
SFO
14h 03m
1 stop
American Airlines Logo
9:50 pm - 4:11 pm
SFO
-
GCM
16h 21m
1 stop
$786American Airlines
Sat, Jun 13 - Wed, Jun 17
American Airlines Logo
12:31 pm - 10:38 pm
GCM
-
SFO
12h 07m
2 stops
American Airlines Logo
6:54 pm - 11:30 am
SFO
-
GCM
14h 36m
2 stops
$791American Airlines
Sat, Jun 13 - Wed, Jun 17

Air Canada flights from Cayman Islands to San Francisco

Our best Air Canada deals on Cayman Islands to San Francisco flight tickets
Air Canada
Aug 27
GCM12:25 pmGeorge Town Owen Roberts Intl
23h 03m
2 stops
SFO9:28 amSan Francisco
Sep 22
SFO7:35 pmSan Francisco
37h 55m
2 stops
GCM11:30 amGeorge Town Owen Roberts Intl
$729
Air Canada
Jun 13
GCM10:55 amGeorge Town Owen Roberts Intl
26h 30m
2 stops
SFO11:25 amSan Francisco
Jun 17
SFO4:30 pmSan Francisco
16h 55m
1 stop
GCM11:25 amGeorge Town Owen Roberts Intl
$741
Air Canada
Jun 13
GCM10:55 amGeorge Town Owen Roberts Intl
12h 15m
1 stop
SFO9:10 pmSan Francisco
Jun 17
SFO4:30 pmSan Francisco
16h 55m
1 stop
GCM11:25 amGeorge Town Owen Roberts Intl
$745

American Airlines flights from Cayman Islands to San Francisco

Our best American Airlines deals on Cayman Islands to San Francisco flight tickets
American Airlines
Jun 13
GCM11:56 amGeorge Town Owen Roberts Intl
14h 03m
1 stop
SFO11:59 pmSan Francisco
Jun 17
SFO9:50 pmSan Francisco
16h 21m
1 stop
GCM4:11 pmGeorge Town Owen Roberts Intl
$786
American Airlines
Jun 13
GCM12:31 pmGeorge Town Owen Roberts Intl
12h 07m
2 stops
SFO10:38 pmSan Francisco
Jun 17
SFO6:54 pmSan Francisco
14h 36m
2 stops
GCM11:30 amGeorge Town Owen Roberts Intl
$791
American Airlines
Jun 13
GCM2:17 pmGeorge Town Owen Roberts Intl
12h 31m
2 stops
SFO12:48 amSan Francisco
Jun 17
SFO6:54 pmSan Francisco
14h 07m
2 stops
GCM11:01 amGeorge Town Owen Roberts Intl
$841

momondo Fare Finder

 
Customize your flight search to find flights from Cayman Islands to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from the Cayman Islands to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sun 7/12

12:45 pm-11:30 pm

2 stops12h 45m

San Francisco

Sun 7/26

10:50 pm-11:50 am

2 stops11h 00m

$710

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 4/25

3:50 pm-9:21 am

1 stop19h 31m

San Francisco

Sat 5/2

8:45 pm-4:00 pm

1 stop17h 15m

$716

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 8/27

12:25 pm-9:28 am

2 stops23h 03m

San Francisco

Tue 9/22

7:35 pm-11:30 am

2 stops37h 55m

$729

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 6/13

10:55 am-11:25 am

2 stops26h 30m

San Francisco

Wed 6/17

4:30 pm-11:25 am

1 stop16h 55m

$741

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 6/13

10:55 am-9:10 pm

1 stop12h 15m

San Francisco

Wed 6/17

4:30 pm-11:25 am

1 stop16h 55m

$745

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 8/27

12:25 pm-3:27 pm

1 stop29h 02m

San Francisco

Tue 9/22

11:10 am-11:30 am

2 stops46h 20m

$747

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 6/13

10:55 am-11:25 am

2 stops26h 30m

San Francisco

Wed 6/17

4:30 pm-11:25 am

1 stop16h 55m

$748

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 4/25

8:50 am-12:17 pm

2 stops53h 27m

San Francisco

Sat 5/2

6:29 pm-4:00 pm

1 stop19h 31m

$784

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 6/13

11:56 am-11:59 pm

1 stop14h 03m

San Francisco

Wed 6/17

9:50 pm-4:11 pm

1 stop16h 21m

$786

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 6/13

12:31 pm-10:38 pm

2 stops12h 07m

San Francisco

Wed 6/17

6:54 pm-11:30 am

2 stops14h 36m

$791

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Cayman Islands to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Cayman Islands to San Francisco flights?

You could potentially save up to 56% on your flight if you consider stops on a Cayman Islands to San Francisco flight.

Cheap Cayman Islands to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cayman Islands to San Francisco

Fastest flight time

20h 57m

Direct flights

None
The fastest flight from Cayman Islands to San Francisco takes 20h 57m
There are no direct flights from Cayman Islands to San Francisco. There are no popular flight routes from Cayman Islands to San Francisco.
Search flight deals

  • When did momondo last update prices for flights from Cayman Islands to San Francisco Airport?

    Prices for flights from Cayman Islands to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from Cayman Islands to San Francisco Airport?

  • How old do you have to be to fly from Cayman Islands to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cayman Islands to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Cayman Islands to San Francisco

Compare and see reviews for airlines that fly from Cayman Islands to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $709Free CancellationRating
7.1
11,531 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Vallejo
Calistoga
Salinas
Daly City
Half Moon Bay
Milpitas
South San Francisco
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Cayman Islands to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Cayman Islands.

Can I find flights from Cayman Islands to San Francisco with flexible booking policies on momondo?

Flights from Cayman Islands to San Francisco with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Cayman Islands to San Francisco?

momondo helps you find the best flight between Cayman Islands and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Cayman Islands to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Cayman Islands and alert you when they change.

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