Cheap flights from St. Louis to Detroit from $54

The cheapest month to fly to Detroit from St. Louis is in April. Flight prices, which tend to average around $324, are often lower during this time because this is during the off-season. If you’re not able to fly to Detroit in April, then May is your next best option. Flight prices from St. Louis to Detroit during May average around $332.

On average, the least expensive day to fly to Detroit from St. Louis is on a Saturday. momondo users have found tickets for Saturday departures for as low as $463. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from St. Louis to Detroit for around $720.

In the evening is the cheapest time of day to fly from St. Louis to Detroit when you can find flight prices for as low as $310. Flying to Detroit in the evening is an ideal time because this is during off-peak travel hours. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $945 on average. Flights to Detroit from St. Louis at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Lambert-St Louis to Detroit Metropolitan Wayne County for the best Lambert-St Louis - Detroit flight prices

You are more likely to see cheaper flights to Detroit from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Detroit for around $375 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Detroit from St. Louis for as low as $279 on momondo.

There are 4 cabin classes available to choose from on St. Louis to Detroit flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 21% on your flight if you consider stops on a St. Louis to Detroit flight.

As of October 2026, prices for St. Louis to Detroit flights are approximately 12% cheaper when compared to flights at the same time last year.

Frontier is the most popular carrier operating from Lambert-St Louis to Detroit

Delta, Southwest and Frontier are the top three most popular airlines that fly to Detroit from St. Louis according to our data. Delta is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Detroit. Keep in mind that there are 3 different airlines that fly to Detroit on a routine basis, so you have a few additional options to choose from.

As of October 2026, there are 15 flights per day flying from St. Louis to Detroit. The most common time of day flights depart is 10:00AM, with 49% of flights taking off at noon.

105 flights are operational weekly from St. Louis to Detroit as of October 2026. The most popular departure day for this route is Fri, with 16% of flights per week taking off on this day.