Cheap flights from St. Louis to Detroit from $54

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from St. Louis is in May. Flight prices, which tend to average around $309, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of May, then book flights to Detroit Metropolitan Wayne County Airport from St. Louis during September instead. Flights to Detroit Metropolitan Wayne County Airport in September, while not as cheap as those in May, still average around $339.

The cheapest day to depart from St. Louis to Detroit Metropolitan Wayne County Airport is on a Saturday when prices can be found for as low as $463. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Tuesday is $720.

Flying to Detroit Metropolitan Wayne County Airport from St. Louis in the evening is the least expensive time of day to depart. momondo users have found prices as low as $310 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly at noon, with an average ticket price of $945. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Lambert-St Louis to Detroit Metropolitan Wayne County for the best Lambert-St Louis - Detroit Metropolitan Wayne County flight prices

You are more likely to see cheaper flights to Detroit Metropolitan Wayne County Airport from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Detroit Metropolitan Wayne County Airport for around $375 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Detroit Metropolitan Wayne County Airport from St. Louis for as low as $279 on momondo.

There are 4 cabin classes available to choose from on St. Louis to Detroit Metropolitan Wayne County Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 21% on your flight if you consider stops on a St. Louis to Detroit Metropolitan Wayne County Airport flight.

As of October 2026, prices for St. Louis to Detroit Metropolitan Wayne County Airport flights are approximately 21% cheaper when compared to flights at the same time last year.

Southwest is the most popular carrier operating from Lambert-St Louis to Detroit Metropolitan Wayne County

Delta, Southwest and Frontier are the top three most popular airlines that fly to Detroit Metropolitan Wayne County Airport from St. Louis according to our data. Delta is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Detroit Metropolitan Wayne County Airport. Keep in mind that there are 3 different airlines that fly to Detroit Metropolitan Wayne County Airport on a routine basis, so you have a few additional options to choose from.

As of October 2026, there are 10 flights per day flying from St. Louis to Detroit Metropolitan Wayne County Airport. The most common time of day flights depart is 10:00AM, with 49% of flights taking off at noon.

75 flights are operational weekly from St. Louis to Detroit Metropolitan Wayne County Airport as of October 2026. The most popular departure day for this route is Wed, with 24% of flights per week taking off on this day.