How long is the flight from South Carolina to Indiana?

Flight times vary depending on what airport in South Carolina you fly out of and what airport in Indiana you fly into. For example, flying from Columbia to Indianapolis takes 3h 10m on average. On the other hand, flying from Greenville to Indianapolis takes 3h 25m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

What airlines fly to Indiana?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Indiana from South Carolina according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 6 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Indiana on average per week?

As of September 2025, 829 flights take off from South Carolina and land in Indiana each week. The most common flight departure day for this route is Thu, with 16% of weekly flights taking off on this day.

What is the cheapest airline that flies from South Carolina to Indiana?

Frontier, Spirit Airlines, and Southwest are the most popular carriers operating from South Carolina to Indiana

When did momondo last update prices for flights from South Carolina to Indiana?

Prices for flights from South Carolina to Indiana are updated daily.

How many operators does momondo search for flights from South Carolina to Indiana?

As of September 2025, there are 8 operators available to choose from for flights from South Carolina to Indiana.

How old do you have to be to fly from South Carolina to Indiana?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Indiana.

What documentation or ID do you need to fly to Indiana?

The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$59 Cheap Flights from South Carolina to Indiana in 2025/26

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Find the cheapest flights from South Carolina to Indiana

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

3:51 pm - 5:13 pmCLT-ORD

2h 22mnonstop

11:51 am - 2:56 pmORD-CLT

2h 05mnonstop

$112Frontier

Find Deal

Sat, Nov 1 - Sun, Nov 2

8:55 am - 6:20 pmCLT-ORD

10h 25m1 stop

6:00 am - 9:08 amORD-CLT

2h 08mnonstop

$113Frontier

Find Deal

Mon, Oct 20 - Thu, Oct 23

4:24 pm - 5:34 pmCLT-ORD

2h 10mnonstop

8:44 pm - 11:53 pmORD-CLT

2h 09mnonstop

$134American Airlines

Find Deal

Wed, Oct 22 - Wed, Oct 22

9:25 am - 10:32 amCLT-ORD

2h 07mnonstop

8:15 am - 11:21 amORD-CLT

2h 06mnonstop

$139American Airlines

Find Deal

Wed, Oct 29 - Sat, Nov 1

4:33 pm - 6:10 pmMYR-ORD

2h 37mnonstop

11:20 am - 2:42 pmORD-MYR

2h 22mnonstop

$147United Airlines

Find Deal

Tue, Oct 14 - Tue, Oct 21

4:33 pm - 6:10 pmMYR-ORD

2h 37mnonstop

10:40 am - 4:56 pmORD-MYR

5h 16m1 stop

$157United Airlines

Find Deal

Tue, Oct 14 - Tue, Oct 21

6:00 am - 5:13 pmCLT-ORD

12h 13m1 stop

11:13 am - 11:29 pmORD-CLT

11h 16m1 stop

$161Spirit Airlines

Find Deal

Wed, Oct 15 - Wed, Oct 22

9:11 am - 4:51 pmMYR-ORD

8h 40m1 stop

11:57 am - 8:06 pmORD-MYR

7h 09m1 stop

$167Spirit Airlines

Find Deal

Wed, Oct 1 - Sat, Oct 4

6:00 am - 8:40 amCLT-MDW

3h 40m1 stop

6:23 pm - 11:03 pmMDW-CLT

3h 40m1 stop

$197Delta

Find Deal

Wed, Oct 29 - Tue, Nov 4

5:05 pm - 10:14 pmCLT-MDW

6h 09m1 stop

6:00 am - 1:42 pmMDW-CLT

6h 42m1 stop

$200Delta

Find Deal

Sat, Oct 11 - Sun, Oct 12

American Airlines flights from South Carolina to Indiana

Our best American Airlines deals on South Carolina to Indiana flight tickets

American Airlines

Oct 22

CLT4:24 pmCharlotte Douglas

2h 10m

ORD5:34 pmChicago O'Hare Intl

Oct 22

ORD8:44 pmChicago O'Hare Intl

2h 09m

CLT11:53 pmCharlotte Douglas

$134

Find similar

American Airlines

Oct 29

CLT9:25 amCharlotte Douglas

2h 07m

ORD10:32 amChicago O'Hare Intl

Nov 1

ORD8:15 amChicago O'Hare Intl

2h 06m

CLT11:21 amCharlotte Douglas

$139

Find similar

American Airlines

Oct 22

CLT1:01 pmCharlotte Douglas

2h 11m

ORD2:12 pmChicago O'Hare Intl

Oct 23

ORD8:44 pmChicago O'Hare Intl

2h 15m

CLT11:59 pmCharlotte Douglas

$151

Find similar

United Airlines flights from South Carolina to Indiana

Our best United Airlines deals on South Carolina to Indiana flight tickets

United Airlines

Oct 14

MYR4:33 pmMyrtle Beach Intl

2h 37m

ORD6:10 pmChicago O'Hare Intl

Oct 21

ORD11:20 amChicago O'Hare Intl

2h 22m

MYR2:42 pmMyrtle Beach Intl

$147

Find similar

United Airlines

Oct 14

MYR4:33 pmMyrtle Beach Intl

2h 37m

ORD6:10 pmChicago O'Hare Intl

Oct 21

ORD10:40 amChicago O'Hare Intl

5h 16m

1 stop

MYR4:56 pmMyrtle Beach Intl

$157

Find similar

United Airlines

Oct 11

CLT5:10 pmCharlotte Douglas

2h 25m

ORD6:35 pmChicago O'Hare Intl

Oct 15

ORD7:15 amChicago O'Hare Intl

2h 16m

CLT10:31 amCharlotte Douglas

$159

Find similar

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 11/1

3:51 pm-5:13 pm

Nonstop2h 22m

Chicago O'Hare Intl

Sun 11/2

11:51 am-2:56 pm

Nonstop2h 05m

$112

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Mon 10/20

8:55 am-6:20 pm

1 stop10h 25m

Chicago O'Hare Intl

Thu 10/23

6:00 am-9:08 am

Nonstop2h 08m

$113

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/22

4:24 pm-5:34 pm

Nonstop2h 10m

Chicago O'Hare Intl

Wed 10/22

8:44 pm-11:53 pm

Nonstop2h 09m

$134

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/29

9:25 am-10:32 am

Nonstop2h 07m

Chicago O'Hare Intl

Sat 11/1

8:15 am-11:21 am

Nonstop2h 06m

$139

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 10/14

4:33 pm-6:10 pm

Nonstop2h 37m

Chicago O'Hare Intl

Tue 10/21

11:20 am-2:42 pm

Nonstop2h 22m

$147

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 10/14

4:33 pm-6:10 pm

Nonstop2h 37m

Chicago O'Hare Intl

Tue 10/21

10:40 am-4:56 pm

1 stop5h 16m

$157

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/15

6:00 am-5:13 pm

1 stop12h 13m

Chicago O'Hare Intl

Wed 10/22

11:13 am-11:29 pm

1 stop11h 16m

$161

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 10/1

9:11 am-4:51 pm

1 stop8h 40m

Chicago O'Hare Intl

Sat 10/4

11:57 am-8:06 pm

1 stop7h 09m

$167

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 10/29

6:00 am-8:40 am

1 stop3h 40m

Chicago Midway

Tue 11/4

6:23 pm-11:03 pm

1 stop3h 40m

$197

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 10/11

5:05 pm-10:14 pm

1 stop6h 09m

Chicago Midway

Sun 10/12

6:00 am-1:42 pm

1 stop6h 42m

$200

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from South Carolina to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from South Carolina is in July. Flight prices, which tend to average around $240, are often lower during this time because this is during the off-season. The month of May is another great option to travel to Indiana, with average flight prices from South Carolina averaging around $290.

What is the cheapest day to depart on your flight to Indiana?

Our data shows that Friday is the least expensive day to fly to Indiana. Tickets to fly out on this day can be as low as $146. On the other hand, Tuesday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $309.

What is the cheapest South Carolina to Indiana flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best South Carolina - Indiana flight prices

How far in advance should I book a flight to Indiana?

You are more likely to see cheaper flights to Indiana from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Indiana for around $361 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Indiana from South Carolina for as low as $260 on momondo.

What cabin class options are available on South Carolina to Indiana flights?

There is only 1 cabin class available to choose from on South Carolina to Indiana flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Indiana flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Indiana.

Cheap South Carolina to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Indiana

Fastest flight time	1h 23m
Direct flights	Every day
Airports in Indiana	4 airports

The fastest flight from South Carolina to Indiana takes 1h 23m

Direct flights go from South Carolina to Indiana every day.

There are 4 airports near Indiana: Chicago O'Hare Intl (ORD), Chicago Midway (MDW), Louisville Intl (SDF), Cincinnati Cinci./N. Kentucky (CVG)

Search flight deals

When did momondo last update prices for flights from South Carolina to Indiana?
Prices for flights from South Carolina to Indiana are updated daily.
How many operators does momondo search for flights from South Carolina to Indiana?
As of September 2025, there are 8 operators available to choose from for flights from South Carolina to Indiana.
How old do you have to be to fly from South Carolina to Indiana?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Indiana.
What documentation or ID do you need to fly to Indiana?
The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from South Carolina to Indiana?
momondo data reveals that the most frequently booked plane model on the route from South Carolina to Indiana is Airbus A320-100/200, representing 38.46% of all bookings. The subsequent popular models are Airbus A319 at 15.38%, Airbus A320neo at 7.69%, and Airbus A321neo at 7.69%.

Best airlines flying from South Carolina to Indiana

Compare and see reviews for airlines that fly from South Carolina to Indiana with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $45	Free Cancellation	Rating 7.2 699 reviews	Search Allegiant Air flights
Spirit Airlines	PriceFrom $149	Free Cancellation	Rating 6.3 8,030 reviews	Search Spirit Airlines flights
Southwest	PriceFrom $189	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights
United Airlines	PriceFrom $190	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights
American Airlines	PriceFrom $198	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $198	Free Cancellation	Rating 7.9 7,964 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Indiana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Indiana. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Indiana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Indiana flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Indiana?

Once you have performed a search for South Carolina to Indiana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Indiana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Indiana from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Indiana trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to Indiana

Popular cities in Indiana

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Cheap flights from South Carolina to Indiana from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Indiana departing on 11/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from South Carolina to Indiana

Cheap round-trip flights

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Cheap last minute flights

Cheap direct flights

American Airlines flights from South Carolina to Indiana

Our best American Airlines deals on South Carolina to Indiana flight tickets

United Airlines flights from South Carolina to Indiana

Our best United Airlines deals on South Carolina to Indiana flight tickets

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Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.

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How to get the cheapest flight ticket from South Carolina to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indiana?

What is the cheapest day to depart on your flight to Indiana?

What is the cheapest South Carolina to Indiana flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best South Carolina - Indiana flight prices

How far in advance should I book a flight to Indiana?

What cabin class options are available on South Carolina to Indiana flights?

There is only 1 cabin class available to choose from on South Carolina to Indiana flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Indiana flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Indiana.

What is the cheapest airline that flies from South Carolina to Indiana?

Frontier, Spirit Airlines, and Southwest are the most popular carriers operating from South Carolina to Indiana

What airlines fly to Indiana?

How many flights depart from South Carolina to Indiana on average per week?

As of September 2025, 829 flights take off from South Carolina and land in Indiana each week. The most common flight departure day for this route is Thu, with 16% of weekly flights taking off on this day.

How long is the flight from South Carolina to Indiana?

Cheap South Carolina to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Indiana

Fastest flight time

Direct flights

Airports in Indiana

When did momondo last update prices for flights from South Carolina to Indiana?

How many operators does momondo search for flights from South Carolina to Indiana?

How old do you have to be to fly from South Carolina to Indiana?

What documentation or ID do you need to fly to Indiana?

What is the most popular plane model from South Carolina to Indiana?

Best airlines flying from South Carolina to Indiana

Compare and see reviews for airlines that fly from South Carolina to Indiana with momondo

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Indiana?

Can I find flights from South Carolina to Indiana with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Indiana?

I’m not ready to book a flight from South Carolina to Indiana right now. Can momondo alert me if prices change?

An easier way to manage your Indiana trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Indiana

Popular cities in Indiana

Popular flights according to clicks in the last 7 days on momondo