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Cheap flights from South America to San Francisco from $204

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South America to San Francisco departing on 5/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South America to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:20 am - 2:34 pm
MDE
-
SFO
16h 14m
2 stops
American Airlines Logo
6:00 am - 10:39 pm
SFO
-
MDE
14h 39m
2 stops
$331American Airlines
Mon, Mar 9 - Tue, Mar 17
American Airlines Logo
12:25 am - 7:15 pm
BOG
-
SFO
20h 50m
1 stop
American Airlines Logo
6:00 am - 9:17 pm
SFO
-
BOG
13h 17m
2 stops
$337American Airlines
Mon, Apr 27 - Tue, May 12
United Airlines Logo
8:30 am - 10:30 pm
BOG
-
SFO
16h 00m
1 stop
United Airlines Logo
12:45 am - 7:20 pm
SFO
-
BOG
16h 35m
1 stop
$350United Airlines
Wed, Apr 15 - Sat, Apr 18
United Airlines Logo
8:30 am - 10:30 pm
BOG
-
SFO
16h 00m
1 stop
United Airlines Logo
6:55 pm - 4:54 am
SFO
-
BOG
31h 59m
1 stop
$352United Airlines
Tue, Apr 28 - Sun, May 17
Avianca Logo
2:10 pm - 11:55 pm
MDE
-
SFO
11h 45m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$391Avianca
Tue, Apr 21 - Sat, Apr 25
Copa Airlines Logo
9:15 am - 6:14 pm
MDE
-
SFO
10h 59m
1 stop
Copa Airlines Logo
8:16 pm - 2:15 pm
SFO
-
MDE
15h 59m
1 stop
$408Copa Airlines
Sat, May 30 - Sat, Jun 20
Copa Airlines Logo
1:20 pm - 11:40 pm
LIM
-
SFO
12h 20m
1 stop
Copa Airlines Logo
8:06 pm - 12:25 pm
SFO
-
LIM
14h 19m
1 stop
$519Copa Airlines
Thu, Mar 26 - Sat, May 2
LATAM Airlines Logo
4:30 pm - 7:07 pm
SCL
-
SFO
29h 37m
2 stops
LATAM Airlines Logo
11:41 am - 7:15 am
SFO
-
SCL
16h 34m
1 stop
$519LATAM Airlines
Mon, May 4 - Tue, May 12
LATAM Airlines Logo
10:30 am - 10:10 am
SCL
-
SFO
26h 40m
2 stops
LATAM Airlines Logo
11:55 am - 5:35 am
SFO
-
SCL
14h 40m
1 stop
$521LATAM Airlines
Fri, May 8 - Wed, May 13
Avianca Logo
7:35 am - 11:55 pm
GRU
-
SFO
20h 20m
2 stops
Avianca Logo
11:55 pm - 10:30 pm
SFO
-
GRU
18h 35m
2 stops
$621Avianca
Tue, Aug 25 - Tue, Oct 6

United Airlines flights from South America to San Francisco

Our best United Airlines deals on South America to San Francisco flight tickets
United Airlines
May 1
BOG8:30 amBogotá El Dorado
29h 48m
1 stop
SFO12:18 pmSan Francisco
May 8
SFO6:55 pmSan Francisco
22h 25m
1 stop
BOG7:20 pmBogotá El Dorado
$350
United Airlines
Apr 28
BOG8:30 amBogotá El Dorado
16h 00m
1 stop
SFO10:30 pmSan Francisco
May 7
SFO11:59 pmSan Francisco
17h 21m
1 stop
BOG7:20 pmBogotá El Dorado
$352
United Airlines
Apr 17
BOG8:30 amBogotá El Dorado
32h 23m
1 stop
SFO2:53 pmSan Francisco
Apr 28
SFO11:59 pmSan Francisco
17h 21m
1 stop
BOG7:20 pmBogotá El Dorado
$353

Avianca flights from South America to San Francisco

Our best Avianca deals on South America to San Francisco flight tickets
Avianca
Mar 13
BOG4:00 amBogotá El Dorado
11h 00m
1 stop
SFO1:00 pmSan Francisco
Apr 14
SFO2:15 pmSan Francisco
9h 45m
1 stop
BOG2:00 amBogotá El Dorado
$371
Avianca
Mar 13
BOG4:00 amBogotá El Dorado
11h 00m
1 stop
SFO1:00 pmSan Francisco
Apr 14
SFO11:55 pmSan Francisco
14h 05m
1 stop
BOG4:00 pmBogotá El Dorado
$372
Avianca
Mar 13
BOG4:00 amBogotá El Dorado
11h 00m
1 stop
SFO1:00 pmSan Francisco
Apr 14
SFO11:55 pmSan Francisco
14h 05m
1 stop
BOG4:00 pmBogotá El Dorado
$373

momondo Fare Finder

 
Customize your flight search to find flights from South America to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from South America to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 3/9

12:20 am-2:34 pm

2 stops16h 14m

San Francisco

Tue 3/17

6:00 am-10:39 pm

2 stops14h 39m

$331

BogotáSan Francisco

BOG - SFO

BOGSFO

Bogotá El Dorado

Mon 4/27

12:25 am-7:15 pm

1 stop20h 50m

San Francisco

Tue 5/12

6:00 am-9:17 pm

2 stops13h 17m

$337

BogotáSan Francisco

BOG - SFO

BOGSFO

Bogotá El Dorado

Wed 4/15

8:30 am-10:30 pm

1 stop16h 00m

San Francisco

Sat 4/18

12:45 am-7:20 pm

1 stop16h 35m

$350

BogotáSan Francisco

BOG - SFO

BOGSFO

Bogotá El Dorado

Tue 4/28

8:30 am-10:30 pm

1 stop16h 00m

San Francisco

Sun 5/17

6:55 pm-4:54 am

1 stop31h 59m

$352

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 4/21

2:10 pm-11:55 pm

1 stop11h 45m

San Francisco

Sat 4/25

11:55 pm-1:10 pm

1 stop11h 15m

$391

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sat 5/30

9:15 am-6:14 pm

1 stop10h 59m

San Francisco

Sat 6/20

8:16 pm-2:15 pm

1 stop15h 59m

$408

LimaSan Francisco

LIM - SFO

LIMSFO

Lima J Chavez Intl

Thu 3/26

1:20 pm-11:40 pm

1 stop12h 20m

San Francisco

Sat 5/2

8:06 pm-12:25 pm

1 stop14h 19m

$519

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 5/4

4:30 pm-7:07 pm

2 stops29h 37m

San Francisco

Tue 5/12

11:41 am-7:15 am

1 stop16h 34m

$519

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Fri 5/8

10:30 am-10:10 am

2 stops26h 40m

San Francisco

Wed 5/13

11:55 am-5:35 am

1 stop14h 40m

$521

Sao PauloSan Francisco

GRU - SFO

GRUSFO

Sao Paulo Guarulhos Intl

Tue 8/25

7:35 am-11:55 pm

2 stops20h 20m

San Francisco

Tue 10/6

11:55 pm-10:30 pm

2 stops18h 35m

$621

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from South America to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of March, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $593.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from South America when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $636 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from South America for as low as $499 on momondo.

Can stopping save me money on South America to San Francisco flights?

You could potentially save up to 15% on your flight if you consider stops on a South America to San Francisco flight.

Cheap South America to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South America to San Francisco

Fastest flight time

0h 00m

Direct flights

None
The fastest flight from South America to San Francisco takes 0h 00m
There are no direct flights from South America to San Francisco. There are no popular flight routes from South America to San Francisco.
Search flight deals

  • When did momondo last update prices for flights from South America to San Francisco Airport?

    Prices for flights from South America to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from South America to San Francisco Airport?

  • How old do you have to be to fly from South America to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South America to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South America to San Francisco

Compare and see reviews for airlines that fly from South America to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $208Free CancellationRating
6.5
2,494 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $230Free CancellationRating
7.5
1,925 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $263Free CancellationRating
7.5
1,557 reviews
Search Copa Airlines flights
DeltaPriceFrom $330Free CancellationRating
7.9
8,245 reviews
Search Delta flights
United AirlinesPriceFrom $377Free CancellationRating
7.4
9,366 reviews
Search United Airlines flights
American AirlinesPriceFrom $481Free CancellationRating
7.1
11,371 reviews
Search American Airlines flights
AeromexicoPriceFrom $527Free CancellationRating
7.4
1,573 reviews
Search Aeromexico flights
Air CanadaPriceFrom $569Free CancellationRating
7.1
10,758 reviews
Search Air Canada flights
GOLPriceFrom $832Free CancellationRating
7.3
1,176 reviews
Search GOL flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Walnut Creek
Hayward
Santa Clara
Big Sur
Berkeley
Calistoga
Fremont
Half Moon Bay
Vallejo
Daly City
Salinas
South San Francisco
Milpitas
Sunnyvale

Why use momondo?

Why should I use momondo to find a flight deal from South America to San Francisco?

It is quick and easy to find South America to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from South America to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from South America on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South America to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South America to San Francisco.

I’m not ready to book a flight from South America to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from South America are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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