Cheap flights from Seattle to South Carolina from $124

The cheapest month to fly to South Carolina from Seattle is in February. Flight prices, which tend to average around $349, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to South Carolina from Seattle during January instead. Flights to South Carolina in January, while not as cheap as those in February, still average around $415.

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $382. The most expensive day to fly to South Carolina is Tuesday, with ticket prices averaging around $527.

Fly from Seattle/Tacoma Intl to Charleston for the best Seattle/Tacoma Intl - South Carolina flight prices

You are more likely to see cheaper flights to South Carolina from Seattle when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $398 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Seattle for as low as $315 on momondo.

There are 4 cabin classes available to choose from on Seattle to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 31% on your flight if you consider stops on a Seattle to South Carolina flight.

Delta, United Airlines, and Southwest are the most popular carriers operating from Seattle/Tacoma Intl to South Carolina

American Airlines, Alaska Airlines and Delta are the top three most popular airlines that fly to South Carolina from Seattle according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

As of September 2026, 2 flights take off from Seattle and land in South Carolina each day. The most common flight departure time for this route is 9:00AM, with 100% of daily flights taking off at noon.

As of September 2026, there are 19 flights per week flying from Seattle to South Carolina. The most common day of the week flights depart is Wed, with 26% of flights taking off on this day.