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Cheap flights from Seattle to Florence from $347

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Seattle to Florence departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Seattle to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:27 pm - 11:08 pm
SEA
-
FLO
7h 41m
1 stop
American Airlines Logo
5:20 am - 12:29 pm
FLO
-
SEA
10h 09m
2 stops
$577American Airlines
Tue, Mar 31 - Sat, Apr 11
American Airlines Logo
7:21 am - 11:08 pm
SEA
-
FLO
12h 47m
2 stops
American Airlines Logo
5:20 am - 12:29 pm
FLO
-
SEA
10h 09m
2 stops
$602American Airlines
Tue, Mar 31 - Sat, Apr 11
American Airlines Logo
12:27 pm - 11:08 pm
SEA
-
FLO
7h 41m
1 stop
American Airlines Logo
4:16 pm - 9:04 pm
FLO
-
SEA
7h 48m
1 stop
$606American Airlines
Tue, Mar 31 - Sat, Apr 11
American Airlines Logo
10:50 am - 10:00 pm
SEA
-
FLO
8h 10m
1 stop
American Airlines Logo
2:35 pm - 8:14 pm
FLO
-
SEA
8h 39m
1 stop
$667American Airlines
Sun, Jun 7 - Mon, Jun 22
American Airlines Logo
10:50 am - 10:00 pm
SEA
-
FLO
8h 10m
1 stop
American Airlines Logo
2:35 pm - 8:14 pm
FLO
-
SEA
8h 39m
1 stop
$687American Airlines
Sun, Jun 7 - Mon, Jun 22
American Airlines Logo
11:58 pm - 2:10 pm
SEA
-
FLO
11h 12m
2 stops
American Airlines Logo
2:35 pm - 8:14 pm
FLO
-
SEA
8h 39m
1 stop
$692American Airlines
Sun, Jun 7 - Mon, Jun 22
American Airlines Logo
10:50 am - 10:00 pm
SEA
-
FLO
8h 10m
1 stop
American Airlines Logo
2:35 pm - 11:39 pm
FLO
-
SEA
12h 04m
2 stops
$712American Airlines
Sun, Jun 7 - Mon, Jun 22
American Airlines Logo
11:58 pm - 2:10 pm
SEA
-
FLO
11h 12m
2 stops
American Airlines Logo
2:35 pm - 11:39 pm
FLO
-
SEA
12h 04m
2 stops
$717American Airlines
Sun, Jun 7 - Mon, Jun 22
American Airlines Logo
7:21 am - 11:57 pm
SEA
-
FLO
13h 36m
2 stops
American Airlines Logo
5:16 am - 12:51 pm
FLO
-
SEA
10h 35m
1 stop
$733American Airlines
Mon, Mar 16 - Fri, Mar 20
American Airlines Logo
7:21 am - 11:57 pm
SEA
-
FLO
13h 36m
2 stops
American Airlines Logo
5:16 am - 3:57 pm
FLO
-
SEA
13h 41m
2 stops
$738American Airlines
Mon, Mar 16 - Fri, Mar 20

American Airlines flights from Seattle to Florence, South Carolina

Our best American Airlines deals on Seattle to Florence, South Carolina flight tickets
American Airlines
Mar 31
SEA12:27 pmSeattle/Tacoma Intl
7h 41m
1 stop
FLO11:08 pmFlorence
Apr 11
FLO5:20 amFlorence
10h 09m
2 stops
SEA12:29 pmSeattle/Tacoma Intl
$577
American Airlines
Mar 31
SEA7:21 amSeattle/Tacoma Intl
12h 47m
2 stops
FLO11:08 pmFlorence
Apr 11
FLO5:20 amFlorence
10h 09m
2 stops
SEA12:29 pmSeattle/Tacoma Intl
$602
American Airlines
Mar 31
SEA12:27 pmSeattle/Tacoma Intl
7h 41m
1 stop
FLO11:08 pmFlorence
Apr 11
FLO4:16 pmFlorence
7h 48m
1 stop
SEA9:04 pmSeattle/Tacoma Intl
$606

momondo Fare Finder

 
Customize your flight search to find flights from Seattle to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Seattle to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Tue 3/31

12:27 pm-11:08 pm

1 stop7h 41m

Florence

Sat 4/11

5:20 am-12:29 pm

2 stops10h 09m

$577

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Tue 3/31

7:21 am-11:08 pm

2 stops12h 47m

Florence

Sat 4/11

5:20 am-12:29 pm

2 stops10h 09m

$602
Quickest round-trip

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Tue 3/31

12:27 pm-11:08 pm

1 stop7h 41m

Florence

Sat 4/11

4:16 pm-9:04 pm

1 stop7h 48m

$606

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sun 6/7

10:50 am-10:00 pm

1 stop8h 10m

Florence

Mon 6/22

2:35 pm-8:14 pm

1 stop8h 39m

$667

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sun 6/7

10:50 am-10:00 pm

1 stop8h 10m

Florence

Mon 6/22

2:35 pm-8:14 pm

1 stop8h 39m

$687

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sun 6/7

11:58 pm-2:10 pm

2 stops11h 12m

Florence

Mon 6/22

2:35 pm-8:14 pm

1 stop8h 39m

$692

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sun 6/7

10:50 am-10:00 pm

1 stop8h 10m

Florence

Mon 6/22

2:35 pm-11:39 pm

2 stops12h 04m

$712

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sun 6/7

11:58 pm-2:10 pm

2 stops11h 12m

Florence

Mon 6/22

2:35 pm-11:39 pm

2 stops12h 04m

$717

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Mon 3/16

7:21 am-11:57 pm

2 stops13h 36m

Florence

Fri 3/20

5:16 am-12:51 pm

1 stop10h 35m

$733

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Mon 3/16

7:21 am-11:57 pm

2 stops13h 36m

Florence

Fri 3/20

5:16 am-3:57 pm

2 stops13h 41m

$738

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Seattle to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Seattle/Tacoma Intl to Florence?

American Airlines is the most popular carrier operating from Seattle/Tacoma Intl to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Alaska Airlines and Delta are the top three most popular airlines that fly to Florence, South Carolina from Seattle according to our data. American Airlines is the first choice among our users, with 68% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 7 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Seattle to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Seattle to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Seattle to Florence, South Carolina (SEA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Seattle to Florence, South Carolina

Fastest flight time

8h 10m

Direct flights

None
The fastest flight from Seattle to Florence, South Carolina takes 8h 10m
There are no direct flights from Seattle to Florence, South Carolina. There are no popular flight routes from Seattle to Florence, South Carolina.
Search flight deals

  • How far is Seattle/Tacoma Intl to Florence by plane?

    The distance between Seattle/Tacoma Intl and Florence is about 2371.0 mi. Typically, this will take 8h 10m by plane in normal conditions.

  • When did momondo last update prices for flights from Seattle/Tacoma Intl Airport to Florence Airport?

    Prices for flights from Seattle/Tacoma Intl Airport to Florence Airport refresh daily.

  • How many operators does momondo search for flights from Seattle/Tacoma Intl Airport to Florence Airport?

  • How old do you have to be to fly from Seattle/Tacoma Intl Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Seattle/Tacoma Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Seattle to Florence, South Carolina?

Best airlines flying from Seattle to Florence, South Carolina

Compare and see reviews for airlines that fly from Seattle to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $386Free CancellationRating
7.1
11,393 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Seattle to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Seattle.

Can I find flights from Seattle to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Seattle on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Seattle to Florence?

Once all potential Seattle to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Seattle to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Seattle to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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