Cheap flights from Sao Paulo to San Francisco from $350

If you aren’t able to travel to San Francisco during the month of May, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $721.

You are more likely to see cheaper flights to San Francisco from Sao Paulo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $855 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Sao Paulo for as low as $598 on momondo.

You could potentially save up to 9% on your flight if you consider stops on a Sao Paulo to San Francisco flight.

As of March 2026, prices for Sao Paulo to San Francisco flights are approximately 25% cheaper when compared to flights at the same time last year.

Avianca, Copa Airlines, and GOL are the most popular carriers operating from Sao Paulo to San Francisco

United Airlines, American Airlines and Copa Airlines are the top three most popular airlines that fly to San Francisco from Sao Paulo according to our data. United Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 8 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 100% of flights between Sao Paulo and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 215 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Panama City (PTY) was the most common stop: 45% of momondo users choosing 1-stop flights on this route connected there.

Flights via Montreal (YUL) offer the lowest average round-trip price of $645.

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 16h 24m.

Dallas (DFW) has the shortest average layover time for this route: 1h 33m.