Cheap flights from Santiago to Houston from $376

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Houston departing on 1/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Multiple Airlines Logo
11:25 pm - 4:08 pmSCL-IAH
19h 43m1 stop
Multiple Airlines Logo
2:32 pm - 7:00 amIAH-SCL
13h 28m1 stop
$530Multiple Airlines
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Tue, Dec 16 - Thu, Jan 22
Multiple Airlines Logo
7:15 am - 7:04 amSCL-IAH
26h 49m2 stops
Multiple Airlines Logo
8:30 am - 6:40 amIAH-SCL
43h 10m2 stops
$583Multiple Airlines
Find Deal
Tue, Dec 16 - Tue, Jan 20
Multiple Airlines Logo
7:15 am - 7:04 amSCL-IAH
26h 49m2 stops
Multiple Airlines Logo
12:13 pm - 2:40 pmIAH-SCL
47h 27m2 stops
$615Multiple Airlines
Find Deal
Tue, Dec 16 - Sun, Jan 18
Multiple Airlines Logo
11:25 pm - 4:08 pmSCL-IAH
19h 43m1 stop
Multiple Airlines Logo
8:30 am - 10:15 pmIAH-SCL
34h 45m2 stops
$616Multiple Airlines
Find Deal
Tue, Dec 16 - Wed, Jan 21
Multiple Airlines Logo
10:35 am - 11:59 pmSCL-IAH
16h 24m1 stop
Multiple Airlines Logo
12:21 pm - 10:15 pmIAH-SCL
30h 54m2 stops
$631Multiple Airlines
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Thu, Feb 12 - Thu, Feb 19
Multiple Airlines Logo
11:25 pm - 4:08 pmSCL-IAH
19h 43m1 stop
Multiple Airlines Logo
4:20 pm - 6:40 amIAH-SCL
35h 20m2 stops
$633Multiple Airlines
Find Deal
Tue, Dec 16 - Mon, Jan 19
LATAM Airlines Logo
4:35 am - 10:33 pmSCL-HOU
20h 58m2 stops
LATAM Airlines Logo
5:04 pm - 2:05 pmHOU-SCL
18h 01m2 stops
$794LATAM Airlines
Find Deal
Wed, Jan 21 - Mon, Jan 26
LATAM Airlines Logo
12:20 am - 10:28 pmSCL-HOU
24h 08m2 stops
LATAM Airlines Logo
5:27 pm - 5:55 pmHOU-SCL
22h 28m2 stops
$880LATAM Airlines
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Tue, Mar 10 - Wed, Mar 18
LATAM Airlines Logo
10:10 pm - 9:40 amSCL-HOU
13h 30m1 stop
LATAM Airlines Logo
5:27 pm - 5:55 pmHOU-SCL
22h 28m2 stops
$881LATAM Airlines
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Wed, Mar 11 - Wed, Mar 18
Delta Logo
10:10 pm - 9:40 amSCL-HOU
13h 30m1 stop
Delta Logo
2:05 pm - 7:40 amHOU-SCL
15h 35m1 stop
$955Delta
Find Deal
Wed, Mar 11 - Wed, Mar 18

Delta flights from Santiago to Houston

Our best Delta deals on Santiago to Houston flight tickets
Delta
Mar 11
SCL10:10 pmSantiago Arturo Merino Benitez
13h 30m
1 stop
HOU9:40 amHouston Hobby
Mar 18
HOU6:00 amHouston Hobby
23h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Delta
Apr 13
SCL8:40 pmSantiago Arturo Merino Benitez
25h 58m
1 stop
HOU9:38 pmHouston Hobby
Apr 24
HOU10:05 amHouston Hobby
19h 55m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Delta
Jan 14
SCL8:15 amSantiago Arturo Merino Benitez
17h 18m
2 stops
HOU10:33 pmHouston Hobby
Feb 12
HOU10:50 amHouston Hobby
15h 45m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez

LATAM Airlines flights from Santiago to Houston

Our best LATAM Airlines deals on Santiago to Houston flight tickets
LATAM Airlines
Dec 9
SCL11:55 pmSantiago Arturo Merino Benitez
27h 00m
1 stop
IAH11:55 pmHouston George Bush Intcntl
Dec 11
IAH5:10 amHouston George Bush Intcntl
20h 20m
2 stops
SCL4:30 amSantiago Arturo Merino Benitez
LATAM Airlines
Jan 21
SCL4:35 amSantiago Arturo Merino Benitez
20h 58m
2 stops
HOU10:33 pmHouston Hobby
Jan 26
HOU5:04 pmHouston Hobby
18h 01m
2 stops
SCL2:05 pmSantiago Arturo Merino Benitez
LATAM Airlines
Feb 11
SCL4:35 amSantiago Arturo Merino Benitez
22h 21m
2 stops
IAH11:56 pmHouston George Bush Intcntl
Feb 19
IAH12:42 pmHouston George Bush Intcntl
31h 43m
2 stops
SCL11:25 pmSantiago Arturo Merino Benitez

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Santiago to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoHouston

SCL - IAH

SCLIAH

Santiago Arturo Merino Benitez

Tue 12/16

11:25 pm-4:08 pm

1 stop19h 43m

Houston George Bush Intcntl

Thu 1/22

2:32 pm-7:00 am

1 stop13h 28m

$530

SantiagoHouston

SCL - IAH

SCLIAH

Santiago Arturo Merino Benitez

Tue 12/16

7:15 am-7:04 am

2 stops26h 49m

Houston George Bush Intcntl

Tue 1/20

8:30 am-6:40 am

2 stops43h 10m

$583

SantiagoHouston

SCL - IAH

SCLIAH

Santiago Arturo Merino Benitez

Tue 12/16

7:15 am-7:04 am

2 stops26h 49m

Houston George Bush Intcntl

Sun 1/18

12:13 pm-2:40 pm

2 stops47h 27m

$615

SantiagoHouston

SCL - IAH

SCLIAH

Santiago Arturo Merino Benitez

Tue 12/16

11:25 pm-4:08 pm

1 stop19h 43m

Houston George Bush Intcntl

Wed 1/21

8:30 am-10:15 pm

2 stops34h 45m

$616

SantiagoHouston

SCL - IAH

SCLIAH

Santiago Arturo Merino Benitez

Thu 2/12

10:35 am-11:59 pm

1 stop16h 24m

Houston George Bush Intcntl

Thu 2/19

12:21 pm-10:15 pm

2 stops30h 54m

$631

SantiagoHouston

SCL - IAH

SCLIAH

Santiago Arturo Merino Benitez

Tue 12/16

11:25 pm-4:08 pm

1 stop19h 43m

Houston George Bush Intcntl

Mon 1/19

4:20 pm-6:40 am

2 stops35h 20m

$633

SantiagoHouston

SCL - HOU

SCLHOU

Santiago Arturo Merino Benitez

Wed 1/21

4:35 am-10:33 pm

2 stops20h 58m

Houston Hobby

Mon 1/26

5:04 pm-2:05 pm

2 stops18h 01m

$794

SantiagoHouston

SCL - HOU

SCLHOU

Santiago Arturo Merino Benitez

Tue 3/10

12:20 am-10:28 pm

2 stops24h 08m

Houston Hobby

Wed 3/18

5:27 pm-5:55 pm

2 stops22h 28m

$880

SantiagoHouston

SCL - HOU

SCLHOU

Santiago Arturo Merino Benitez

Wed 3/11

10:10 pm-9:40 am

1 stop13h 30m

Houston Hobby

Wed 3/18

5:27 pm-5:55 pm

2 stops22h 28m

$881

SantiagoHouston

SCL - HOU

SCLHOU

Santiago Arturo Merino Benitez

Wed 3/11

10:10 pm-9:40 am

1 stop13h 30m

Houston Hobby

Wed 3/18

2:05 pm-7:40 am

1 stop15h 35m

$955

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Houston from

How to get the cheapest flight ticket from Santiago to Houston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Houston?

The month of October is, on average, the cheapest month to fly to Houston from Santiago, with most prices found around $426. The month of September is another great option to travel to Houston, with average flight prices from Santiago averaging around $468.

What is the cheapest day to depart on your flight to Houston?

On average, the least expensive day to fly to Houston from Santiago is on a Friday. momondo users have found tickets for Friday departures for as low as $1,062. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Houston on Wednesday is $1,175.

What is the cheapest time of day to depart on your flight to Houston?

Our data shows that the cheapest Santiago to Houston flights are usually those with departure times in the afternoon. Our users have found flights to Houston in the afternoon for as low as $673. Try not to purchase tickets in the evening because they tend to be around $945. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Santiago Arturo Merino Benitez to Houston flight route?

Fly from Santiago Arturo Merino Benitez to Houston George Bush Intcntl for the best Santiago Arturo Merino Benitez - Houston flight prices

How far in advance should I book a flight to Houston?

You are more likely to see cheaper flights to Houston from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Houston for around $973 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Houston from Santiago for as low as $508 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Houston flights?

There are 3 cabin classes available to choose from on Santiago Arturo Merino Benitez to Houston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Santiago to Houston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Houston

Fastest flight time

9h 20m

Direct flights

Every day

Airports in Houston

1 airport
The fastest flight from Santiago to Houston takes 9h 20m
Direct flights go from Santiago to Houston every day.
There is 1 airport near Houston: Houston George Bush Intcntl (IAH)
  • How far is Santiago Arturo Merino Benitez to Houston by plane?

    The distance between Santiago Arturo Merino Benitez and Houston is about 4652.9 mi. Flights usually cover this in 13h 04m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Houston?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Houston were last updated today.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Houston?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Houston?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Houston.

  • What documentation or ID do you need to fly to Houston?

    The required travel and health documents for your Houston trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Houston. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Santiago to Houston

Compare and see reviews for airlines that fly from Santiago to Houston with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $258Free CancellationRating
6.6
2,477 reviews
Search Avianca flights
United AirlinesPriceFrom $1,149Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Houston?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santiago to Houston for you.

Can I find flights from Santiago to Houston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to Houston flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to Houston?

momondo helps you find the best flight between Santiago and Houston by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to Houston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to Houston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Fri 1/2
Fri 1/9

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