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Cheap flights from Santiago de los Caballeros to San Francisco from $450

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago de los Caballeros to San Francisco departing on 1/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago de los Caballeros to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
4:10 am - 2:07 pm
STI
-
SFO
13h 57m1 stop
JetBlue Logo
12:30 pm - 9:39 am
SFO
-
STI
17h 09m1 stop
$450JetBlue
Fri, Jan 30 - Sat, Feb 7
JetBlue Logo
4:10 am - 5:15 pm
STI
-
SFO
17h 05m1 stop
JetBlue Logo
8:30 pm - 12:41 pm
SFO
-
STI
12h 11m1 stop
$451JetBlue
Thu, Jan 29 - Fri, Feb 6
JetBlue Logo
5:10 am - 6:55 pm
STI
-
SFO
17h 45m1 stop
JetBlue Logo
3:25 pm - 12:41 pm
SFO
-
STI
17h 16m1 stop
$460JetBlue
Mon, Feb 2 - Fri, Feb 6
JetBlue Logo
4:10 am - 5:15 pm
STI
-
SFO
17h 05m1 stop
JetBlue Logo
7:00 am - 11:02 am
SFO
-
STI
24h 02m2 stops
$482JetBlue
Fri, Jan 30 - Sat, Feb 7
JetBlue Logo
12:12 pm - 11:29 pm
STI
-
SFO
15h 17m1 stop
JetBlue Logo
3:05 pm - 9:39 am
SFO
-
STI
14h 34m1 stop
$489JetBlue
Fri, Jan 23 - Sun, Jan 25
JetBlue Logo
11:47 am - 10:30 am
STI
-
SFO
26h 43m1 stop
JetBlue Logo
11:59 pm - 10:37 am
SFO
-
STI
30h 38m1 stop
$666JetBlue
Mon, Jan 12 - Tue, Jan 13
American Airlines Logo
6:00 am - 7:12 pm
STI
-
SFO
17h 12m2 stops
American Airlines Logo
6:00 am - 9:46 pm
SFO
-
STI
11h 46m2 stops
$698American Airlines
Fri, Jan 30 - Fri, Feb 6
American Airlines Logo
6:00 am - 10:25 pm
STI
-
SFO
20h 25m2 stops
American Airlines Logo
6:00 am - 9:46 pm
SFO
-
STI
11h 46m2 stops
$745American Airlines
Sat, Jan 31 - Sat, Feb 7
American Airlines Logo
6:00 am - 5:24 pm
STI
-
SFO
15h 24m2 stops
American Airlines Logo
6:00 am - 9:46 pm
SFO
-
STI
11h 46m2 stops
$748American Airlines
Sat, Jan 31 - Sat, Feb 7
American Airlines Logo
6:00 am - 3:58 pm
STI
-
SFO
13h 58m2 stops
American Airlines Logo
11:36 pm - 9:46 pm
SFO
-
STI
18h 10m2 stops
$916American Airlines
Thu, Jan 1 - Mon, Jan 12

American Airlines flights from Santiago de los Caballeros to San Francisco

Our best American Airlines deals on Santiago de los Caballeros to San Francisco flight tickets
American Airlines
Jan 30
STI6:00 amSantiago de los Caballeros
17h 12m
2 stops
SFO7:12 pmSan Francisco
Feb 6
SFO6:00 amSan Francisco
11h 46m
2 stops
STI9:46 pmSantiago de los Caballeros
$698
Find similar
American Airlines
Jan 31
STI6:00 amSantiago de los Caballeros
20h 25m
2 stops
SFO10:25 pmSan Francisco
Feb 7
SFO6:00 amSan Francisco
11h 46m
2 stops
STI9:46 pmSantiago de los Caballeros
$745
Find similar
American Airlines
Jan 31
STI6:00 amSantiago de los Caballeros
15h 24m
2 stops
SFO5:24 pmSan Francisco
Feb 7
SFO6:00 amSan Francisco
11h 46m
2 stops
STI9:46 pmSantiago de los Caballeros
$748
Find similar

JetBlue flights from Santiago de los Caballeros to San Francisco

Our best JetBlue deals on Santiago de los Caballeros to San Francisco flight tickets
JetBlue
Feb 1
STI5:10 amSantiago de los Caballeros
12h 45m
1 stop
SFO1:55 pmSan Francisco
Feb 8
SFO8:00 amSan Francisco
23h 02m
1 stop
STI11:02 amSantiago de los Caballeros
$447
Find similar
JetBlue
Jan 30
STI4:10 amSantiago de los Caballeros
13h 57m
1 stop
SFO2:07 pmSan Francisco
Feb 7
SFO12:30 pmSan Francisco
17h 09m
1 stop
STI9:39 amSantiago de los Caballeros
$450
Find similar
JetBlue
Jan 29
STI4:10 amSantiago de los Caballeros
17h 05m
1 stop
SFO5:15 pmSan Francisco
Feb 6
SFO8:30 pmSan Francisco
12h 11m
1 stop
STI12:41 pmSantiago de los Caballeros
$451
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Santiago de los Caballeros to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 1/30

4:10 am-2:07 pm

1 stop13h 57m

San Francisco

Sat 2/7

12:30 pm-9:39 am

1 stop17h 09m

$450

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 1/29

4:10 am-5:15 pm

1 stop17h 05m

San Francisco

Fri 2/6

8:30 pm-12:41 pm

1 stop12h 11m

$451

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Mon 2/2

5:10 am-6:55 pm

1 stop17h 45m

San Francisco

Fri 2/6

3:25 pm-12:41 pm

1 stop17h 16m

$460

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 1/30

4:10 am-5:15 pm

1 stop17h 05m

San Francisco

Sat 2/7

7:00 am-11:02 am

2 stops24h 02m

$482

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 1/23

12:12 pm-11:29 pm

1 stop15h 17m

San Francisco

Sun 1/25

3:05 pm-9:39 am

1 stop14h 34m

$489

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Mon 1/12

11:47 am-10:30 am

1 stop26h 43m

San Francisco

Tue 1/13

11:59 pm-10:37 am

1 stop30h 38m

$666

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 1/30

6:00 am-7:12 pm

2 stops17h 12m

San Francisco

Fri 2/6

6:00 am-9:46 pm

2 stops11h 46m

$698

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sat 1/31

6:00 am-10:25 pm

2 stops20h 25m

San Francisco

Sat 2/7

6:00 am-9:46 pm

2 stops11h 46m

$745

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sat 1/31

6:00 am-5:24 pm

2 stops15h 24m

San Francisco

Sat 2/7

6:00 am-9:46 pm

2 stops11h 46m

$748

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 1/1

6:00 am-3:58 pm

2 stops13h 58m

San Francisco

Mon 1/12

11:36 pm-9:46 pm

2 stops18h 10m

$916

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Santiago de los Caballeros to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago de los Caballeros to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago de los Caballeros to San Francisco (STI to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago de los Caballeros to San Francisco

Fastest flight time

12h 06m

Direct flights

None
The fastest flight from Santiago de los Caballeros to San Francisco takes 12h 06m
There are no direct flights from Santiago de los Caballeros to San Francisco. There are no popular flight routes from Santiago de los Caballeros to San Francisco.
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  • How far is Santiago de los Caballeros to San Francisco by plane?

    San Francisco is 3332.2 mi away from Santiago de los Caballeros. Flights usually cover this in 12h 06m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago de los Caballeros Airport to San Francisco Airport?

    Prices for flights from Santiago de los Caballeros Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago de los Caballeros Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santiago de los Caballeros Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • How do I get Price Alerts for flights from Santiago de los Caballeros to San Francisco?

    Search flight deals from Santiago de los Caballeros to San Francisco. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Santiago de los Caballeros to San Francisco with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    We compare prices from 700+ competitors to help you find the price that works best for you. momondo operates in over 30 international markets, bringing you access to a wide range of fares and deals. Search for your travel using momondo for a diverse range of options from airlines and OTAs.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Berkeley
Santa Clara
Walnut Creek
Fremont
Daly City
Half Moon Bay
Vallejo
Salinas
Livermore
Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Santiago de los Caballeros to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago de los Caballeros to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago de los Caballeros to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Santiago de los Caballeros which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago de los Caballeros to San Francisco?

momondo helps you find the best flight between Santiago de los Caballeros and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago de los Caballeros to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago de los Caballeros to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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