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Cheap flights from Santiago de los Caballeros to San Francisco from $212

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago de los Caballeros to San Francisco departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago de los Caballeros to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
10:31 am - 11:59 pm
STI
-
SFO
17h 28m
1 stop
JetBlue Logo
12:30 pm - 3:26 am
SFO
-
STI
11h 56m
1 stop
$441JetBlue
Thu, Feb 26 - Tue, Mar 10
JetBlue Logo
6:00 am - 8:49 pm
STI
-
SFO
17h 49m
1 stop
JetBlue Logo
8:25 am - 12:21 am
SFO
-
STI
12h 56m
1 stop
$492JetBlue
Wed, Mar 11 - Wed, Mar 18
JetBlue Logo
10:31 am - 11:59 pm
STI
-
SFO
17h 28m
1 stop
JetBlue Logo
10:39 pm - 9:21 am
SFO
-
STI
30h 42m
1 stop
$500JetBlue
Thu, Feb 26 - Sun, Mar 1
JetBlue Logo
6:00 am - 8:49 pm
STI
-
SFO
17h 49m
1 stop
JetBlue Logo
8:44 pm - 1:47 am
SFO
-
STI
26h 03m
2 stops
$528JetBlue
Wed, Mar 11 - Wed, Mar 18
JetBlue Logo
3:10 am - 5:54 pm
STI
-
SFO
17h 44m
1 stop
JetBlue Logo
11:14 pm - 8:03 am
SFO
-
STI
29h 49m
1 stop
$536JetBlue
Thu, Mar 26 - Mon, Mar 30
JetBlue Logo
3:10 am - 5:54 pm
STI
-
SFO
17h 44m
1 stop
JetBlue Logo
11:10 am - 8:20 am
SFO
-
STI
18h 10m
1 stop
$563JetBlue
Wed, Mar 25 - Wed, Apr 1
JetBlue Logo
4:10 am - 7:31 pm
STI
-
SFO
18h 21m
1 stop
JetBlue Logo
8:44 pm - 9:15 pm
SFO
-
STI
21h 31m
2 stops
$567JetBlue
Fri, Mar 13 - Fri, Mar 20
JetBlue Logo
3:10 am - 5:54 pm
STI
-
SFO
17h 44m
1 stop
JetBlue Logo
11:14 pm - 8:03 am
SFO
-
STI
29h 49m
1 stop
$569JetBlue
Thu, Mar 26 - Mon, Mar 30
JetBlue Logo
8:35 pm - 9:23 am
STI
-
SFO
15h 48m
1 stop
JetBlue Logo
9:30 pm - 12:45 pm
SFO
-
STI
12h 15m
1 stop
$582JetBlue
Sun, Apr 26 - Sun, May 3
JetBlue Logo
3:10 am - 5:54 pm
STI
-
SFO
17h 44m
1 stop
JetBlue Logo
10:00 pm - 8:03 am
SFO
-
STI
31h 03m
2 stops
$617JetBlue
Thu, Mar 26 - Mon, Mar 30

JetBlue flights from Santiago de los Caballeros to San Francisco

Our best JetBlue deals on Santiago de los Caballeros to San Francisco flight tickets
JetBlue
Feb 26
STI10:31 amSantiago de los Caballeros
17h 28m
1 stop
SFO11:59 pmSan Francisco
Mar 10
SFO12:30 pmSan Francisco
11h 56m
1 stop
STI3:26 amSantiago de los Caballeros
$441
JetBlue
Mar 11
STI6:00 amSantiago de los Caballeros
17h 49m
1 stop
SFO8:49 pmSan Francisco
Mar 18
SFO8:25 amSan Francisco
12h 56m
1 stop
STI12:21 amSantiago de los Caballeros
$492
JetBlue
Feb 26
STI10:31 amSantiago de los Caballeros
17h 28m
1 stop
SFO11:59 pmSan Francisco
Mar 1
SFO10:39 pmSan Francisco
30h 42m
1 stop
STI9:21 amSantiago de los Caballeros
$500

American Airlines flights from Santiago de los Caballeros to San Francisco

Our best American Airlines deals on Santiago de los Caballeros to San Francisco flight tickets
American Airlines
Mar 11
STI7:00 amSantiago de los Caballeros
13h 48m
2 stops
SFO5:48 pmSan Francisco
Mar 17
SFO12:25 amSan Francisco
17h 04m
2 stops
STI8:29 pmSantiago de los Caballeros
$728
American Airlines
Feb 26
STI8:00 amSantiago de los Caballeros
19h 59m
1 stop
SFO11:59 pmSan Francisco
Mar 10
SFO7:00 pmSan Francisco
14h 30m
2 stops
STI12:30 pmSantiago de los Caballeros
$740
American Airlines
May 13
STI1:32 pmSantiago de los Caballeros
22h 44m
2 stops
SFO9:16 amSan Francisco
May 20
SFO1:21 pmSan Francisco
21h 56m
1 stop
STI2:17 pmSantiago de los Caballeros
$741

momondo Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santiago de los Caballeros to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 2/26

10:31 am-11:59 pm

1 stop17h 28m

San Francisco

Tue 3/10

12:30 pm-3:26 am

1 stop11h 56m

$441

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Wed 3/11

6:00 am-8:49 pm

1 stop17h 49m

San Francisco

Wed 3/18

8:25 am-12:21 am

1 stop12h 56m

$492

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 2/26

10:31 am-11:59 pm

1 stop17h 28m

San Francisco

Sun 3/1

10:39 pm-9:21 am

1 stop30h 42m

$500

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Wed 3/11

6:00 am-8:49 pm

1 stop17h 49m

San Francisco

Wed 3/18

8:44 pm-1:47 am

2 stops26h 03m

$528

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 3/26

3:10 am-5:54 pm

1 stop17h 44m

San Francisco

Mon 3/30

11:14 pm-8:03 am

1 stop29h 49m

$536

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Wed 3/25

3:10 am-5:54 pm

1 stop17h 44m

San Francisco

Wed 4/1

11:10 am-8:20 am

1 stop18h 10m

$563

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 3/13

4:10 am-7:31 pm

1 stop18h 21m

San Francisco

Fri 3/20

8:44 pm-9:15 pm

2 stops21h 31m

$567

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 3/26

3:10 am-5:54 pm

1 stop17h 44m

San Francisco

Mon 3/30

11:14 pm-8:03 am

1 stop29h 49m

$569

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Sun 4/26

8:35 pm-9:23 am

1 stop15h 48m

San Francisco

Sun 5/3

9:30 pm-12:45 pm

1 stop12h 15m

$582

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 3/26

3:10 am-5:54 pm

1 stop17h 44m

San Francisco

Mon 3/30

10:00 pm-8:03 am

2 stops31h 03m

$617

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santiago de los Caballeros to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santiago de los Caballeros to San Francisco?

JetBlue is the most popular carrier operating from Santiago de los Caballeros to San Francisco

When to book flights from Santiago de los Caballeros to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago de los Caballeros to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago de los Caballeros to San Francisco (STI to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago de los Caballeros to San Francisco

Fastest flight time

12h 45m

Direct flights

None
The fastest flight from Santiago de los Caballeros to San Francisco takes 12h 45m
There are no direct flights from Santiago de los Caballeros to San Francisco. There are no popular flight routes from Santiago de los Caballeros to San Francisco.
Search flight deals

  • How far is Santiago de los Caballeros to San Francisco by plane?

    San Francisco is 3332.2 mi away from Santiago de los Caballeros. Flights usually cover this in 12h 45m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago de los Caballeros Airport to San Francisco Airport?

    Prices for flights from Santiago de los Caballeros Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago de los Caballeros Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santiago de los Caballeros Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Santa Clara
Berkeley
Walnut Creek
Fremont
Daly City
Half Moon Bay
Salinas
Vallejo
Livermore
Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Santiago de los Caballeros to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago de los Caballeros to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago de los Caballeros to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Santiago de los Caballeros which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago de los Caballeros to San Francisco?

momondo helps you find the best flight between Santiago de los Caballeros and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago de los Caballeros to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago de los Caballeros to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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