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Cheap flights from Santiago de los Caballeros to San Francisco from $379

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago de los Caballeros to San Francisco departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago de los Caballeros to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
6:01 am - 7:44 pm
STI
-
SFO
17h 43m
1 stop
JetBlue Logo
1:05 pm - 8:02 am
SFO
-
STI
14h 57m
1 stop
$631JetBlue
Thu, Nov 12 - Mon, Nov 16
JetBlue Logo
8:13 am - 11:51 pm
STI
-
SFO
18h 38m
1 stop
JetBlue Logo
11:10 pm - 1:27 pm
SFO
-
STI
11h 17m
1 stop
$676JetBlue
Tue, Sep 8 - Tue, Sep 15
JetBlue Logo
8:13 am - 11:51 pm
STI
-
SFO
18h 38m
1 stop
JetBlue Logo
11:10 pm - 1:27 pm
SFO
-
STI
11h 17m
1 stop
$680JetBlue
Tue, Sep 8 - Tue, Sep 15
JetBlue Logo
4:43 pm - 11:35 pm
STI
-
SFO
10h 52m
1 stop
JetBlue Logo
6:00 am - 1:51 am
SFO
-
STI
15h 51m
1 stop
$701JetBlue
Thu, Nov 5 - Wed, Nov 18
JetBlue Logo
6:48 pm - 10:13 am
STI
-
SFO
18h 25m
1 stop
JetBlue Logo
11:10 pm - 1:27 pm
SFO
-
STI
11h 17m
1 stop
$707JetBlue
Tue, Sep 8 - Tue, Sep 15
JetBlue Logo
6:01 am - 7:35 pm
STI
-
SFO
17h 34m
1 stop
JetBlue Logo
8:51 pm - 3:33 pm
SFO
-
STI
14h 42m
1 stop
$710JetBlue
Thu, Nov 12 - Mon, Nov 16
JetBlue Logo
6:48 pm - 10:13 am
STI
-
SFO
18h 25m
1 stop
JetBlue Logo
7:50 am - 2:25 am
SFO
-
STI
15h 35m
1 stop
$719JetBlue
Tue, Sep 8 - Tue, Sep 15
JetBlue Logo
6:01 am - 7:44 pm
STI
-
SFO
17h 43m
1 stop
JetBlue Logo
6:00 am - 1:51 am
SFO
-
STI
15h 51m
1 stop
$746JetBlue
Thu, Nov 12 - Mon, Nov 16
American Airlines Logo
8:30 am - 10:18 pm
STI
-
SFO
16h 48m
2 stops
American Airlines Logo
10:54 pm - 2:15 pm
SFO
-
STI
12h 21m
1 stop
$816American Airlines
Tue, Sep 8 - Tue, Sep 15
American Airlines Logo
3:35 pm - 9:52 am
STI
-
SFO
21h 17m
2 stops
American Airlines Logo
10:54 pm - 2:15 pm
SFO
-
STI
12h 21m
1 stop
$816American Airlines
Tue, Sep 8 - Tue, Sep 15

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United Airlines flights from Santiago de los Caballeros to San Francisco

Our best United Airlines deals on Santiago de los Caballeros to San Francisco flight tickets
United Airlines
Jan 22
STI6:00 amSantiago de los Caballeros
21h 51m
1 stop
SFO11:51 pmSan Francisco
Jan 25
SFO10:50 pmSan Francisco
21h 01m
1 stop
STI11:51 pmSantiago de los Caballeros
$812
United Airlines
Sep 12
STI6:00 amSantiago de los Caballeros
12h 04m
1 stop
SFO3:04 pmSan Francisco
Sep 19
SFO6:50 pmSan Francisco
15h 07m
2 stops
STI12:57 pmSantiago de los Caballeros
$1,551
United Airlines
Nov 12
STI6:00 amSantiago de los Caballeros
17h 28m
2 stops
SFO7:28 pmSan Francisco
Nov 16
SFO11:59 pmSan Francisco
10h 54m
1 stop
STI2:53 pmSantiago de los Caballeros
$3,283

JetBlue flights from Santiago de los Caballeros to San Francisco

Our best JetBlue deals on Santiago de los Caballeros to San Francisco flight tickets
JetBlue
Nov 12
STI6:01 amSantiago de los Caballeros
17h 43m
1 stop
SFO7:44 pmSan Francisco
Nov 16
SFO1:05 pmSan Francisco
14h 57m
1 stop
STI8:02 amSantiago de los Caballeros
$631
JetBlue
Sep 8
STI8:13 amSantiago de los Caballeros
18h 38m
1 stop
SFO11:51 pmSan Francisco
Sep 15
SFO11:10 pmSan Francisco
11h 17m
1 stop
STI1:27 pmSantiago de los Caballeros
$676
JetBlue
Sep 8
STI8:13 amSantiago de los Caballeros
18h 38m
1 stop
SFO11:51 pmSan Francisco
Sep 15
SFO11:10 pmSan Francisco
11h 17m
1 stop
STI1:27 pmSantiago de los Caballeros
$680

momondo Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from Santiago de los Caballeros to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 11/12

6:01 am-7:44 pm

1 stop17h 43m

San Francisco

Mon 11/16

1:05 pm-8:02 am

1 stop14h 57m

$631

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 9/8

8:13 am-11:51 pm

1 stop18h 38m

San Francisco

Tue 9/15

11:10 pm-1:27 pm

1 stop11h 17m

$676

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 9/8

8:13 am-11:51 pm

1 stop18h 38m

San Francisco

Tue 9/15

11:10 pm-1:27 pm

1 stop11h 17m

$680
Quickest round-trip

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 11/5

4:43 pm-11:35 pm

1 stop10h 52m

San Francisco

Wed 11/18

6:00 am-1:51 am

1 stop15h 51m

$701

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 9/8

6:48 pm-10:13 am

1 stop18h 25m

San Francisco

Tue 9/15

11:10 pm-1:27 pm

1 stop11h 17m

$707

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 11/12

6:01 am-7:35 pm

1 stop17h 34m

San Francisco

Mon 11/16

8:51 pm-3:33 pm

1 stop14h 42m

$710

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 9/8

6:48 pm-10:13 am

1 stop18h 25m

San Francisco

Tue 9/15

7:50 am-2:25 am

1 stop15h 35m

$719

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 11/12

6:01 am-7:44 pm

1 stop17h 43m

San Francisco

Mon 11/16

6:00 am-1:51 am

1 stop15h 51m

$746

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 9/8

8:30 am-10:18 pm

2 stops16h 48m

San Francisco

Tue 9/15

10:54 pm-2:15 pm

1 stop12h 21m

$816

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 9/8

3:35 pm-9:52 am

2 stops21h 17m

San Francisco

Tue 9/15

10:54 pm-2:15 pm

1 stop12h 21m

$816

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santiago de los Caballeros to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santiago de los Caballeros to San Francisco?

JetBlue is the most popular carrier operating from Santiago de los Caballeros to San Francisco

When to book flights from Santiago de los Caballeros to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago de los Caballeros to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago de los Caballeros to San Francisco (STI to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago de los Caballeros to San Francisco

Fastest flight time

10h 47m

Direct flights

None
The fastest flight from Santiago de los Caballeros to San Francisco takes 10h 47m
There are no direct flights from Santiago de los Caballeros to San Francisco. There are no popular flight routes from Santiago de los Caballeros to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago de los Caballeros to San Francisco

  • How far is Santiago de los Caballeros to San Francisco by plane?

    San Francisco is 3331.5 mi away from Santiago de los Caballeros. Flights usually cover this in 10h 47m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago de los Caballeros Airport to San Francisco Airport?

    Prices for flights from Santiago de los Caballeros Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago de los Caballeros Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santiago de los Caballeros Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Fremont
Berkeley
Hayward
Walnut Creek
Bodega Bay
Sonoma
Roseville
Santa Clara
Vallejo
Salinas
Sunnyvale
Burlingame
Milpitas
Daly City
Palo Alto
Big Sur

Why use momondo?

Why should I use momondo to find a flight deal from Santiago de los Caballeros to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago de los Caballeros to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago de los Caballeros to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Santiago de los Caballeros which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago de los Caballeros to San Francisco?

momondo helps you find the best flight between Santiago de los Caballeros and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago de los Caballeros to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago de los Caballeros to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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