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Cheap flights from Santiago de los Caballeros to San Francisco from $386

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago de los Caballeros to San Francisco departing on 10/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago de los Caballeros to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
4:43 pm - 11:35 pm
STI
-
SFO
10h 52m
1 stop
JetBlue Logo
6:00 am - 1:51 am
SFO
-
STI
15h 51m
1 stop
$742JetBlue
Fri, Nov 6 - Tue, Nov 10
JetBlue Logo
4:43 pm - 11:35 pm
STI
-
SFO
10h 52m
1 stop
JetBlue Logo
10:55 pm - 2:54 pm
SFO
-
STI
11h 59m
1 stop
$753JetBlue
Fri, Nov 6 - Tue, Nov 10
JetBlue Logo
4:43 pm - 11:35 pm
STI
-
SFO
10h 52m
1 stop
JetBlue Logo
6:00 am - 1:51 am
SFO
-
STI
15h 51m
1 stop
$759JetBlue
Fri, Nov 6 - Tue, Nov 10
JetBlue Logo
9:10 am - 9:47 am
STI
-
SFO
27h 37m
1 stop
JetBlue Logo
10:40 pm - 11:51 pm
SFO
-
STI
22h 11m
1 stop
$790JetBlue
Thu, Jul 2 - Tue, Jul 14
American Airlines Logo
9:00 am - 10:23 pm
STI
-
SFO
16h 23m
2 stops
American Airlines Logo
5:29 am - 9:29 pm
SFO
-
STI
13h 00m
2 stops
$877American Airlines
Tue, Jul 14 - Wed, Jul 22
Frontier Logo
11:09 am - 7:26 pm
STI
-
SFO
35h 17m
2 stops
Frontier Logo
10:10 pm - 9:59 am
SFO
-
STI
32h 49m
2 stops
$885Frontier
Thu, Jul 2 - Tue, Jul 14
American Airlines Logo
9:00 am - 10:23 pm
STI
-
SFO
16h 23m
2 stops
American Airlines Logo
5:29 am - 9:29 pm
SFO
-
STI
13h 00m
2 stops
$886American Airlines
Tue, Jul 14 - Wed, Jul 22
Delta Logo
8:59 pm - 12:19 pm
STI
-
SFO
18h 20m
1 stop
Delta Logo
4:00 pm - 12:27 pm
SFO
-
STI
17h 27m
1 stop
$895Delta
Tue, Jul 14 - Wed, Jul 22
JetBlue Logo
6:55 pm - 10:05 am
STI
-
SFO
18h 10m
1 stop
JetBlue Logo
11:00 am - 11:51 pm
SFO
-
STI
9h 51m
1 stop
$933JetBlue
Thu, Jul 9 - Tue, Jul 14
American Airlines Logo
9:00 am - 10:28 pm
STI
-
SFO
16h 28m
2 stops
American Airlines Logo
5:29 am - 9:29 pm
SFO
-
STI
13h 00m
2 stops
$941American Airlines
Tue, Jul 14 - Wed, Jul 22

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JetBlue flights from Santiago de los Caballeros to San Francisco

Our best JetBlue deals on Santiago de los Caballeros to San Francisco flight tickets
JetBlue
Nov 6
STI4:43 pmSantiago de los Caballeros
10h 52m
1 stop
SFO11:35 pmSan Francisco
Nov 10
SFO6:00 amSan Francisco
15h 51m
1 stop
STI1:51 amSantiago de los Caballeros
$742
JetBlue
Nov 6
STI4:43 pmSantiago de los Caballeros
10h 52m
1 stop
SFO11:35 pmSan Francisco
Nov 10
SFO10:55 pmSan Francisco
11h 59m
1 stop
STI2:54 pmSantiago de los Caballeros
$753
JetBlue
Nov 6
STI4:43 pmSantiago de los Caballeros
10h 52m
1 stop
SFO11:35 pmSan Francisco
Nov 10
SFO6:00 amSan Francisco
15h 51m
1 stop
STI1:51 amSantiago de los Caballeros
$759

American Airlines flights from Santiago de los Caballeros to San Francisco

Our best American Airlines deals on Santiago de los Caballeros to San Francisco flight tickets
American Airlines
Jul 14
STI9:00 amSantiago de los Caballeros
16h 23m
2 stops
SFO10:23 pmSan Francisco
Jul 22
SFO5:29 amSan Francisco
13h 00m
2 stops
STI9:29 pmSantiago de los Caballeros
$877
American Airlines
Jul 14
STI9:00 amSantiago de los Caballeros
16h 23m
2 stops
SFO10:23 pmSan Francisco
Jul 22
SFO5:29 amSan Francisco
13h 00m
2 stops
STI9:29 pmSantiago de los Caballeros
$886
American Airlines
Jul 14
STI9:00 amSantiago de los Caballeros
16h 28m
2 stops
SFO10:28 pmSan Francisco
Jul 22
SFO5:29 amSan Francisco
13h 00m
2 stops
STI9:29 pmSantiago de los Caballeros
$941

momondo Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Santiago de los Caballeros to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 11/6

4:43 pm-11:35 pm

1 stop10h 52m

San Francisco

Tue 11/10

6:00 am-1:51 am

1 stop15h 51m

$742
Quickest round-trip

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 11/6

4:43 pm-11:35 pm

1 stop10h 52m

San Francisco

Tue 11/10

10:55 pm-2:54 pm

1 stop11h 59m

$753

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Fri 11/6

4:43 pm-11:35 pm

1 stop10h 52m

San Francisco

Tue 11/10

6:00 am-1:51 am

1 stop15h 51m

$759

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 7/2

9:10 am-9:47 am

1 stop27h 37m

San Francisco

Tue 7/14

10:40 pm-11:51 pm

1 stop22h 11m

$790

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 7/14

9:00 am-10:23 pm

2 stops16h 23m

San Francisco

Wed 7/22

5:29 am-9:29 pm

2 stops13h 00m

$877

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 7/2

11:09 am-7:26 pm

2 stops35h 17m

San Francisco

Tue 7/14

10:10 pm-9:59 am

2 stops32h 49m

$885

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 7/14

9:00 am-10:23 pm

2 stops16h 23m

San Francisco

Wed 7/22

5:29 am-9:29 pm

2 stops13h 00m

$886

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 7/14

8:59 pm-12:19 pm

1 stop18h 20m

San Francisco

Wed 7/22

4:00 pm-12:27 pm

1 stop17h 27m

$895

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Thu 7/9

6:55 pm-10:05 am

1 stop18h 10m

San Francisco

Tue 7/14

11:00 am-11:51 pm

1 stop9h 51m

$933

Santiago de los CaballerosSan Francisco

STI - SFO

STISFO

Santiago de los Caballeros

Tue 7/14

9:00 am-10:28 pm

2 stops16h 28m

San Francisco

Wed 7/22

5:29 am-9:29 pm

2 stops13h 00m

$941

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santiago de los Caballeros to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santiago de los Caballeros to San Francisco?

JetBlue, Delta, and American Airlines are the most popular carriers operating from Santiago de los Caballeros to San Francisco

When to book flights from Santiago de los Caballeros to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago de los Caballeros to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago de los Caballeros to San Francisco (STI to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago de los Caballeros to San Francisco

Fastest flight time

10h 52m

Direct flights

None
The fastest flight from Santiago de los Caballeros to San Francisco takes 10h 52m
There are no direct flights from Santiago de los Caballeros to San Francisco. There are no popular flight routes from Santiago de los Caballeros to San Francisco.
Search flight deals

Frequently asked questions about flying from Santiago de los Caballeros to San Francisco

  • How far is Santiago de los Caballeros to San Francisco by plane?

    San Francisco is 3331.5 mi away from Santiago de los Caballeros. Flights usually cover this in 10h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santiago de los Caballeros Airport to San Francisco Airport?

    Prices for flights from Santiago de los Caballeros Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago de los Caballeros Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santiago de los Caballeros Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Hayward
Bodega Bay
Roseville
Fremont
Walnut Creek
Santa Clara
South San Francisco
Berkeley
Vallejo
Sunnyvale
Salinas
Big Sur
Pacific Grove
Daly City
Burlingame
Calistoga

Why use momondo?

Why should I use momondo to find a flight deal from Santiago de los Caballeros to San Francisco?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago de los Caballeros to San Francisco. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago de los Caballeros to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Santiago de los Caballeros which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago de los Caballeros to San Francisco?

momondo helps you find the best flight between Santiago de los Caballeros and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago de los Caballeros to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago de los Caballeros to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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