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Cheap flights from Santa Ana to Columbia from $343

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Columbia departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:45 am - 5:58 pmSNA-CAE
8h 13m1 stop
Delta Logo
11:55 am - 6:50 pmCAE-SNA
9h 55m1 stop
$499Delta
Find Deal
Wed, Mar 25 - Sat, Mar 28
United Airlines Logo
6:41 pm - 9:59 amSNA-CAE
12h 18m2 stops
United Airlines Logo
5:24 pm - 9:23 amCAE-SNA
18h 59m2 stops
$507United Airlines
Find Deal
Sun, Nov 9 - Fri, Nov 14
Delta Logo
6:45 am - 5:58 pmSNA-CAE
8h 13m1 stop
Delta Logo
11:55 am - 6:50 pmCAE-SNA
9h 55m1 stop
$523Delta
Find Deal
Wed, Mar 25 - Sat, Mar 28
Delta Logo
7:15 pm - 9:28 amSNA-CAE
11h 13m2 stops
Delta Logo
11:55 am - 6:50 pmCAE-SNA
9h 55m1 stop
$564Delta
Find Deal
Wed, Mar 25 - Sat, Mar 28
United Airlines Logo
9:05 pm - 9:59 amSNA-CAE
9h 54m2 stops
United Airlines Logo
10:34 am - 1:03 pmCAE-SNA
29h 29m3 stops
$603United Airlines
Find Deal
Sun, Nov 9 - Fri, Nov 14
Delta Logo
7:15 pm - 9:28 amSNA-CAE
11h 13m2 stops
Delta Logo
5:40 am - 6:17 pmCAE-SNA
15h 37m2 stops
$632Delta
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
7:57 pm - 10:11 amSNA-CAE
11h 14m2 stops
American Airlines Logo
7:08 am - 6:07 pmCAE-SNA
13h 59m2 stops
$652American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
2:47 pm - 12:07 amSNA-CAE
6h 20m1 stop
American Airlines Logo
1:51 pm - 7:57 pmCAE-SNA
9h 06m1 stop
$685American Airlines
Find Deal
Sun, Nov 9 - Fri, Nov 14
American Airlines Logo
11:42 am - 11:56 pmSNA-CAE
9h 14m2 stops
American Airlines Logo
4:18 pm - 8:43 pmCAE-SNA
7h 25m1 stop
$1,188American Airlines
Find Deal
Fri, Nov 28 - Mon, Dec 1
American Airlines Logo
11:42 am - 11:56 pmSNA-CAE
9h 14m2 stops
American Airlines Logo
3:09 pm - 9:53 pmCAE-SNA
9h 44m2 stops
$1,193American Airlines
Find Deal
Fri, Nov 28 - Mon, Dec 1

Delta flights from Santa Ana to Columbia

Our best Delta deals on Santa Ana to Columbia flight tickets
Delta
Mar 25
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 13m
1 stop
CAE5:58 pmColumbia Metropolitan
Mar 28
CAE11:55 amColumbia Metropolitan
9h 55m
1 stop
SNA6:50 pmSanta Ana J. Wayne/Orange Cnty
$499
Find similar
Delta
Mar 25
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 13m
1 stop
CAE5:58 pmColumbia Metropolitan
Mar 28
CAE11:55 amColumbia Metropolitan
9h 55m
1 stop
SNA6:50 pmSanta Ana J. Wayne/Orange Cnty
$523
Find similar
Delta
Mar 25
SNA7:15 pmSanta Ana J. Wayne/Orange Cnty
11h 13m
2 stops
CAE9:28 amColumbia Metropolitan
Mar 28
CAE11:55 amColumbia Metropolitan
9h 55m
1 stop
SNA6:50 pmSanta Ana J. Wayne/Orange Cnty
$564
Find similar

United Airlines flights from Santa Ana to Columbia

Our best United Airlines deals on Santa Ana to Columbia flight tickets
United Airlines
Nov 9
SNA6:41 pmSanta Ana J. Wayne/Orange Cnty
12h 18m
2 stops
CAE9:59 amColumbia Metropolitan
Nov 14
CAE5:24 pmColumbia Metropolitan
18h 59m
2 stops
SNA9:23 amSanta Ana J. Wayne/Orange Cnty
$507
Find similar
United Airlines
Nov 9
SNA9:05 pmSanta Ana J. Wayne/Orange Cnty
9h 54m
2 stops
CAE9:59 amColumbia Metropolitan
Nov 14
CAE10:34 amColumbia Metropolitan
29h 29m
3 stops
SNA1:03 pmSanta Ana J. Wayne/Orange Cnty
$603
Find similar
United Airlines
Oct 28
SNA9:05 pmSanta Ana J. Wayne/Orange Cnty
9h 54m
2 stops
CAE9:59 amColumbia Metropolitan
Oct 31
CAE2:50 pmColumbia Metropolitan
21h 33m
2 stops
SNA9:23 amSanta Ana J. Wayne/Orange Cnty
$627
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 19, 2025.
Use the filters below to find and compare flights from Santa Ana to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 3/25

6:45 am-5:58 pm

1 stop8h 13m

Columbia Metropolitan

Sat 3/28

11:55 am-6:50 pm

1 stop9h 55m

$499

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Sun 11/9

6:41 pm-9:59 am

2 stops12h 18m

Columbia Metropolitan

Fri 11/14

5:24 pm-9:23 am

2 stops18h 59m

$507

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 3/25

6:45 am-5:58 pm

1 stop8h 13m

Columbia Metropolitan

Sat 3/28

11:55 am-6:50 pm

1 stop9h 55m

$523

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 3/25

7:15 pm-9:28 am

2 stops11h 13m

Columbia Metropolitan

Sat 3/28

11:55 am-6:50 pm

1 stop9h 55m

$564

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Sun 11/9

9:05 pm-9:59 am

2 stops9h 54m

Columbia Metropolitan

Fri 11/14

10:34 am-1:03 pm

3 stops29h 29m

$603

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 3/25

7:15 pm-9:28 am

2 stops11h 13m

Columbia Metropolitan

Sat 3/28

5:40 am-6:17 pm

2 stops15h 37m

$632

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 3/25

7:57 pm-10:11 am

2 stops11h 14m

Columbia Metropolitan

Sat 3/28

7:08 am-6:07 pm

2 stops13h 59m

$652

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Sun 11/9

2:47 pm-12:07 am

1 stop6h 20m

Columbia Metropolitan

Fri 11/14

1:51 pm-7:57 pm

1 stop9h 06m

$685

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Fri 11/28

11:42 am-11:56 pm

2 stops9h 14m

Columbia Metropolitan

Mon 12/1

4:18 pm-8:43 pm

1 stop7h 25m

$1,188

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Fri 11/28

11:42 am-11:56 pm

2 stops9h 14m

Columbia Metropolitan

Mon 12/1

3:09 pm-9:53 pm

2 stops9h 44m

$1,193

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from Santa Ana to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Columbia?

On average, the least expensive day to fly to Columbia from Santa Ana is on a Thursday. momondo users have found tickets for Thursday departures for as low as $420. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Columbia on Sunday is $541.

What is the cheapest time of day to depart on your flight to Columbia?

In the evening is the cheapest time of day to fly from Santa Ana to Columbia when you can find flight prices for as low as $456. Flying to Columbia in the evening is an ideal time because this is during off-peak travel hours. Flights in the morning are often more expensive with an average ticket price of $513.

When to book flights from Santa Ana to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Columbia (SNA to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Columbia

Direct flights

None
There are no direct flights from Santa Ana to Columbia. There are no popular flight routes from Santa Ana to Columbia.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Columbia Metropolitan by plane?

    Santa Ana J. Wayne/Orange Cnty and Columbia Metropolitan are 2100.0 mi apart from one another. A reasonable flight in good conditions will take 6h 20m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The necessary travel and health documents for your Columbia Metropolitan Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana to Columbia?

Best airlines flying from Santa Ana to Columbia

Compare and see reviews for airlines that fly from Santa Ana to Columbia with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,026 reviews
Search American Airlines flights
DeltaPriceFrom $363Free CancellationRating
7.9
7,976 reviews
Search Delta flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Ana to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Ana to Columbia with flexible booking policies on momondo?

Flights from Santa Ana to Columbia with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Columbia?

Once you have performed a search for Santa Ana to Columbia flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santa Ana to Columbia right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Columbia from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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