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Cheap flights from Santa Ana, California to Columbia from $333

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Columbia departing on 2/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana, California to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:03 pm - 9:28 am
SNA
-
CAE
13h 25m
2 stops
Delta Logo
5:35 am - 11:49 am
CAE
-
SNA
9h 14m
1 stop
$394Delta
Tue, Feb 3 - Sat, Feb 7
Delta Logo
7:15 pm - 9:18 am
SNA
-
CAE
11h 03m
2 stops
Delta Logo
4:28 pm - 10:12 pm
CAE
-
SNA
8h 44m
1 stop
$449Delta
Thu, Apr 2 - Mon, Apr 6
United Airlines Logo
10:51 am - 11:44 pm
SNA
-
CAE
9h 53m
2 stops
United Airlines Logo
10:10 am - 9:19 pm
CAE
-
SNA
14h 09m
2 stops
$482United Airlines
Tue, Feb 3 - Sat, Feb 7
American Airlines Logo
12:52 pm - 10:58 pm
SNA
-
CAE
7h 06m
1 stop
American Airlines Logo
7:08 am - 12:02 pm
CAE
-
SNA
7h 54m
1 stop
$488American Airlines
Wed, Feb 4 - Sat, Feb 7
American Airlines Logo
12:52 pm - 10:58 pm
SNA
-
CAE
7h 06m
1 stop
American Airlines Logo
6:08 am - 2:09 pm
CAE
-
SNA
11h 01m
2 stops
$493American Airlines
Wed, Feb 4 - Sat, Feb 7
United Airlines Logo
9:00 am - 11:44 pm
SNA
-
CAE
11h 44m
2 stops
United Airlines Logo
2:37 pm - 10:24 pm
CAE
-
SNA
10h 47m
1 stop
$494United Airlines
Wed, Feb 4 - Sun, Feb 8
Delta Logo
11:56 am - 9:20 pm
SNA
-
CAE
6h 24m
1 stop
Delta Logo
4:28 pm - 10:12 pm
CAE
-
SNA
8h 44m
1 stop
$524Delta
Thu, Apr 2 - Mon, Apr 6
United Airlines Logo
7:10 am - 11:44 pm
SNA
-
CAE
13h 34m
2 stops
United Airlines Logo
2:49 pm - 10:24 pm
CAE
-
SNA
10h 35m
2 stops
$550United Airlines
Wed, Feb 4 - Sun, Feb 8
Delta Logo
6:45 am - 4:18 pm
SNA
-
CAE
6h 33m
1 stop
Delta Logo
5:35 am - 11:49 am
CAE
-
SNA
9h 14m
1 stop
$654Delta
Tue, Feb 3 - Sat, Feb 7
American Airlines Logo
7:48 pm - 10:37 am
SNA
-
CAE
11h 49m
2 stops
American Airlines Logo
2:39 pm - 9:17 pm
CAE
-
SNA
9h 38m
1 stop
$685American Airlines
Tue, Mar 17 - Fri, Mar 20

Delta flights from Santa Ana, California to Columbia

Our best Delta deals on Santa Ana, California to Columbia flight tickets
Delta
Feb 3
SNA5:03 pmSanta Ana J. Wayne/Orange Cnty
13h 25m
2 stops
CAE9:28 amColumbia Metropolitan
Feb 7
CAE5:35 amColumbia Metropolitan
9h 14m
1 stop
SNA11:49 amSanta Ana J. Wayne/Orange Cnty
$394
Delta
Apr 2
SNA7:15 pmSanta Ana J. Wayne/Orange Cnty
11h 03m
2 stops
CAE9:18 amColumbia Metropolitan
Apr 6
CAE4:28 pmColumbia Metropolitan
8h 44m
1 stop
SNA10:12 pmSanta Ana J. Wayne/Orange Cnty
$449
Delta
Apr 2
SNA11:56 amSanta Ana J. Wayne/Orange Cnty
6h 24m
1 stop
CAE9:20 pmColumbia Metropolitan
Apr 6
CAE4:28 pmColumbia Metropolitan
8h 44m
1 stop
SNA10:12 pmSanta Ana J. Wayne/Orange Cnty
$524

United Airlines flights from Santa Ana, California to Columbia

Our best United Airlines deals on Santa Ana, California to Columbia flight tickets
United Airlines
Feb 3
SNA10:51 amSanta Ana J. Wayne/Orange Cnty
9h 53m
2 stops
CAE11:44 pmColumbia Metropolitan
Feb 7
CAE10:10 amColumbia Metropolitan
14h 09m
2 stops
SNA9:19 pmSanta Ana J. Wayne/Orange Cnty
$482
United Airlines
Feb 4
SNA9:00 amSanta Ana J. Wayne/Orange Cnty
11h 44m
2 stops
CAE11:44 pmColumbia Metropolitan
Feb 8
CAE2:37 pmColumbia Metropolitan
10h 47m
1 stop
SNA10:24 pmSanta Ana J. Wayne/Orange Cnty
$494
United Airlines
Feb 4
SNA7:10 amSanta Ana J. Wayne/Orange Cnty
13h 34m
2 stops
CAE11:44 pmColumbia Metropolitan
Feb 8
CAE2:49 pmColumbia Metropolitan
10h 35m
2 stops
SNA10:24 pmSanta Ana J. Wayne/Orange Cnty
$550

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

5:03 pm-9:28 am

2 stops13h 25m

Columbia Metropolitan

Sat 2/7

5:35 am-11:49 am

1 stop9h 14m

$394

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Thu 4/2

7:15 pm-9:18 am

2 stops11h 03m

Columbia Metropolitan

Mon 4/6

4:28 pm-10:12 pm

1 stop8h 44m

$449

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

10:51 am-11:44 pm

2 stops9h 53m

Columbia Metropolitan

Sat 2/7

10:10 am-9:19 pm

2 stops14h 09m

$482

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

12:52 pm-10:58 pm

1 stop7h 06m

Columbia Metropolitan

Sat 2/7

7:08 am-12:02 pm

1 stop7h 54m

$488

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

12:52 pm-10:58 pm

1 stop7h 06m

Columbia Metropolitan

Sat 2/7

6:08 am-2:09 pm

2 stops11h 01m

$493

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

9:00 am-11:44 pm

2 stops11h 44m

Columbia Metropolitan

Sun 2/8

2:37 pm-10:24 pm

1 stop10h 47m

$494

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Thu 4/2

11:56 am-9:20 pm

1 stop6h 24m

Columbia Metropolitan

Mon 4/6

4:28 pm-10:12 pm

1 stop8h 44m

$524

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

7:10 am-11:44 pm

2 stops13h 34m

Columbia Metropolitan

Sun 2/8

2:49 pm-10:24 pm

2 stops10h 35m

$550

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

6:45 am-4:18 pm

1 stop6h 33m

Columbia Metropolitan

Sat 2/7

5:35 am-11:49 am

1 stop9h 14m

$654

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

7:48 pm-10:37 am

2 stops11h 49m

Columbia Metropolitan

Fri 3/20

2:39 pm-9:17 pm

1 stop9h 38m

$685

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from Santa Ana, California to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santa Ana, California to Columbia flights?

You could potentially save up to 51% on your flight if you consider stops on a Santa Ana, California to Columbia flight.

When to book flights from Santa Ana, California to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Columbia (SNA to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Columbia

Fastest flight time

5h 45m

Direct flights

None
The fastest flight from Santa Ana, California to Columbia takes 5h 45m
There are no direct flights from Santa Ana, California to Columbia. There are no popular flight routes from Santa Ana, California to Columbia.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Columbia Metropolitan by plane?

    Santa Ana J. Wayne/Orange Cnty and Columbia Metropolitan are 2100.0 mi apart from one another. A reasonable flight in good conditions will take 5h 45m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The necessary travel and health documents for your Columbia Metropolitan Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Columbia?

Best airlines flying from Santa Ana, California to Columbia

Compare and see reviews for airlines that fly from Santa Ana, California to Columbia with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,164 reviews
Search American Airlines flights
DeltaPriceFrom $363Free CancellationRating
7.9
8,076 reviews
Search Delta flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Ana to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Ana to Columbia with flexible booking policies on momondo?

Flights from Santa Ana to Columbia with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Columbia?

Once you have performed a search for Santa Ana to Columbia flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santa Ana to Columbia right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Columbia from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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