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Cheap flights from Santa Ana to Columbia from $349

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Columbia departing on 6/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:00 pm - 11:55 pm
SNA
-
CAE
6h 55m
1 stop
Delta Logo
5:10 pm - 10:28 pm
CAE
-
SNA
8h 18m
1 stop
$349Delta
Mon, Jun 8 - Tue, Jun 16
American Airlines Logo
10:38 am - 10:30 pm
SNA
-
CAE
8h 52m
1 stop
American Airlines Logo
4:18 pm - 8:00 pm
CAE
-
SNA
6h 42m
1 stop
$369American Airlines
Wed, Aug 26 - Tue, Sep 1
Delta Logo
9:20 pm - 9:18 am
SNA
-
CAE
8h 58m
1 stop
Delta Logo
6:50 am - 11:44 am
CAE
-
SNA
7h 54m
1 stop
$399Delta
Fri, Apr 3 - Fri, Apr 10
American Airlines Logo
10:38 am - 10:30 pm
SNA
-
CAE
8h 52m
1 stop
American Airlines Logo
4:18 pm - 9:50 pm
CAE
-
SNA
8h 32m
2 stops
$462American Airlines
Wed, Aug 26 - Tue, Sep 1
United Airlines Logo
7:00 pm - 9:47 am
SNA
-
CAE
11h 47m
2 stops
United Airlines Logo
2:29 pm - 9:50 pm
CAE
-
SNA
10h 21m
2 stops
$522United Airlines
Wed, Aug 26 - Tue, Sep 1
American Airlines Logo
7:45 am - 6:01 pm
SNA
-
CAE
7h 16m
1 stop
American Airlines Logo
12:28 pm - 6:29 pm
CAE
-
SNA
9h 01m
1 stop
$549American Airlines
Sat, May 16 - Mon, May 18
Delta Logo
11:56 am - 9:20 pm
SNA
-
CAE
6h 24m
1 stop
Delta Logo
4:28 pm - 10:12 pm
CAE
-
SNA
8h 44m
1 stop
$552Delta
Sun, Apr 5 - Sun, Apr 12
Delta Logo
2:00 pm - 11:55 pm
SNA
-
CAE
6h 55m
1 stop
Delta Logo
5:10 pm - 10:28 pm
CAE
-
SNA
8h 18m
1 stop
$554Delta
Mon, Jun 8 - Mon, Jun 15
American Airlines Logo
7:45 am - 6:01 pm
SNA
-
CAE
7h 16m
1 stop
American Airlines Logo
4:12 pm - 9:14 pm
CAE
-
SNA
8h 02m
1 stop
$558American Airlines
Sat, May 16 - Sun, May 17
United Airlines Logo
6:45 am - 2:12 pm
SNA
-
CAE
28h 27m
1 stop
United Airlines Logo
10:18 am - 8:51 pm
CAE
-
SNA
13h 33m
2 stops
$563United Airlines
Wed, Aug 26 - Sat, Aug 29

Delta flights from Santa Ana to Columbia

Our best Delta deals on Santa Ana to Columbia flight tickets
Delta
Apr 3
SNA9:20 pmSanta Ana J. Wayne/Orange Cnty
8h 58m
1 stop
CAE9:18 amColumbia Metropolitan
Apr 10
CAE6:50 amColumbia Metropolitan
7h 54m
1 stop
SNA11:44 amSanta Ana J. Wayne/Orange Cnty
$399
Delta
Apr 23
SNA9:20 pmSanta Ana J. Wayne/Orange Cnty
8h 54m
1 stop
CAE9:14 amColumbia Metropolitan
Apr 30
CAE5:47 pmColumbia Metropolitan
7h 27m
1 stop
SNA10:14 pmSanta Ana J. Wayne/Orange Cnty
$439
Delta
Mar 14
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 42m
1 stop
CAE6:27 pmColumbia Metropolitan
Mar 16
CAE4:28 pmColumbia Metropolitan
8h 44m
1 stop
SNA10:12 pmSanta Ana J. Wayne/Orange Cnty
$502

United Airlines flights from Santa Ana to Columbia

Our best United Airlines deals on Santa Ana to Columbia flight tickets
United Airlines
Mar 10
SNA8:49 amSanta Ana J. Wayne/Orange Cnty
11h 55m
2 stops
CAE11:44 pmColumbia Metropolitan
Mar 16
CAE3:35 pmColumbia Metropolitan
9h 51m
1 stop
SNA10:26 pmSanta Ana J. Wayne/Orange Cnty
$527
United Airlines
Mar 10
SNA11:15 amSanta Ana J. Wayne/Orange Cnty
9h 29m
2 stops
CAE11:44 pmColumbia Metropolitan
Mar 16
CAE2:52 pmColumbia Metropolitan
10h 34m
2 stops
SNA10:26 pmSanta Ana J. Wayne/Orange Cnty
$532
United Airlines
Mar 18
SNA10:52 amSanta Ana J. Wayne/Orange Cnty
9h 52m
2 stops
CAE11:44 pmColumbia Metropolitan
Mar 24
CAE6:15 amColumbia Metropolitan
15h 20m
2 stops
SNA6:35 pmSanta Ana J. Wayne/Orange Cnty
$560

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 9, 2026.
Use the filters below to find and compare flights from Santa Ana to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Mon 6/8

2:00 pm-11:55 pm

1 stop6h 55m

Columbia Metropolitan

Tue 6/16

5:10 pm-10:28 pm

1 stop8h 18m

$349

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

10:38 am-10:30 pm

1 stop8h 52m

Columbia Metropolitan

Tue 9/1

4:18 pm-8:00 pm

1 stop6h 42m

$369

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Fri 4/3

9:20 pm-9:18 am

1 stop8h 58m

Columbia Metropolitan

Fri 4/10

6:50 am-11:44 am

1 stop7h 54m

$399

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

10:38 am-10:30 pm

1 stop8h 52m

Columbia Metropolitan

Tue 9/1

4:18 pm-9:50 pm

2 stops8h 32m

$462

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

7:00 pm-9:47 am

2 stops11h 47m

Columbia Metropolitan

Tue 9/1

2:29 pm-9:50 pm

2 stops10h 21m

$522

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Sat 5/16

7:45 am-6:01 pm

1 stop7h 16m

Columbia Metropolitan

Mon 5/18

12:28 pm-6:29 pm

1 stop9h 01m

$549
Quickest round-trip

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Sun 4/5

11:56 am-9:20 pm

1 stop6h 24m

Columbia Metropolitan

Sun 4/12

4:28 pm-10:12 pm

1 stop8h 44m

$552

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Mon 6/8

2:00 pm-11:55 pm

1 stop6h 55m

Columbia Metropolitan

Mon 6/15

5:10 pm-10:28 pm

1 stop8h 18m

$554

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Sat 5/16

7:45 am-6:01 pm

1 stop7h 16m

Columbia Metropolitan

Sun 5/17

4:12 pm-9:14 pm

1 stop8h 02m

$558

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

6:45 am-2:12 pm

1 stop28h 27m

Columbia Metropolitan

Sat 8/29

10:18 am-8:51 pm

2 stops13h 33m

$563

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from Santa Ana to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santa Ana to Columbia flights?

You could potentially save up to 54% on your flight if you consider stops on a Santa Ana to Columbia flight.

When to book flights from Santa Ana to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Columbia (SNA to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Columbia

Fastest flight time

6h 54m

Direct flights

None
The fastest flight from Santa Ana to Columbia takes 6h 54m
There are no direct flights from Santa Ana to Columbia. There are no popular flight routes from Santa Ana to Columbia.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Columbia Metropolitan by plane?

    Santa Ana J. Wayne/Orange Cnty and Columbia Metropolitan are 2100.0 mi apart from one another. A reasonable flight in good conditions will take 6h 54m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The necessary travel and health documents for your Columbia Metropolitan Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana to Columbia?

Best airlines flying from Santa Ana to Columbia

Compare and see reviews for airlines that fly from Santa Ana to Columbia with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,403 reviews
Search American Airlines flights
DeltaPriceFrom $363Free CancellationRating
7.9
8,272 reviews
Search Delta flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Ana to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Ana to Columbia with flexible booking policies on momondo?

Flights from Santa Ana to Columbia with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Columbia?

Once you have performed a search for Santa Ana to Columbia flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santa Ana to Columbia right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Columbia from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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