Cheap flights from San Francisco to Indiana from $109

The cheapest month to fly to Indiana from San Francisco is in September. Flight prices, which tend to average around $358, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Indiana, with average flight prices from San Francisco averaging around $359.

Our data shows that Saturday is the least expensive day to fly to Indiana. Tickets to fly out on this day can be as low as $382. On the other hand, Sunday is the most expensive day to depart from San Francisco because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $484.

Our data shows that the cheapest San Francisco to Indiana flights are usually those with departure times in the afternoon. Our users have found flights to Indiana in the afternoon for as low as $367. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $495 on average. Flights to Indiana from San Francisco in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from San Francisco to Indianapolis for the best San Francisco - Indiana flight prices

You are more likely to see cheaper flights to Indiana from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Indiana for around $397 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Indiana from San Francisco for as low as $314 on momondo.

There are 4 cabin classes available to choose from on San Francisco to Indiana flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Southwest, and Delta are the most popular carriers operating from San Francisco to Indiana

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Indiana from San Francisco according to our data. United Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 6 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

70 flights are operational daily from San Francisco to Indiana as of March 2026. The most popular departure time for this route is 1:00PM, with 100% of flights per day taking off in the afternoon.

The number of flights available between San Francisco and Indiana is 492 per week as of March 2026. The most frequent departure day is Fri, with 17% of weekly flights leaving on this day.