How many flights depart from San Diego to South Carolina on average per week?

54 flights are operational weekly from San Diego to South Carolina as of March 2026. The most popular departure day for this route is Thu, with 20% of flights per week taking off on this day.

What is the cheapest airline that flies from San Diego to South Carolina?

Delta, United Airlines, and American Airlines are the most popular carriers operating from San Diego to South Carolina

What airlines fly to South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to South Carolina from San Diego according to our data. American Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from San Diego Airport to South Carolina?

Prices for flights from San Diego Airport to South Carolina refresh daily.

How many operators does momondo search for flights from San Diego Airport to South Carolina?

As of March 2026, there are 8 operators available to choose from for flights from San Diego Airport to South Carolina.

How old do you have to be to fly from San Diego Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$80 Cheap Flights from San Diego to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from San Diego to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:03 pm - 11:02 pm

SAN

GSP

6h 59m

1 stop

5:12 pm - 10:00 pm

GSP

SAN

7h 48m

1 stop

$299American Airlines

Tue, May 12 - Tue, May 19

8:45 am - 7:33 pm

SAN

CHS

7h 48m

1 stop

5:07 pm - 9:25 pm

CHS

SAN

7h 18m

1 stop

$300United Airlines

Tue, Apr 28 - Wed, May 6

10:20 am - 9:40 pm

SAN

GSP

8h 20m

2 stops

5:05 pm - 9:20 pm

GSP

SAN

7h 15m

1 stop

$304Southwest

Tue, May 12 - Tue, May 19

6:45 am - 8:00 pm

SAN

CHS

10h 15m

2 stops

4:15 pm - 10:50 pm

CHS

SAN

9h 35m

2 stops

$315Southwest

Tue, Jun 2 - Tue, Jun 9

9:15 pm - 10:28 am

SAN

CHS

10h 13m

1 stop

11:09 am - 8:04 pm

CHS

SAN

11h 55m

1 stop

$334JetBlue

Sat, Apr 25 - Sat, May 2

9:45 pm - 9:27 am

SAN

SAV

8h 42m

1 stop

4:59 pm - 9:20 pm

SAV

SAN

7h 21m

1 stop

$339Delta

Tue, Apr 28 - Wed, May 6

12:33 pm - 11:46 am

SAN

MYR

20h 13m

1 stop

6:14 pm - 5:59 pm

MYR

SAN

26h 45m

2 stops

$340Multiple Airlines

Fri, May 15 - Mon, May 18

9:15 pm - 9:52 am

SAN

SAV

9h 37m

1 stop

10:41 am - 8:00 pm

SAV

SAN

12h 19m

1 stop

$343JetBlue

Sat, May 2 - Fri, May 8

10:15 pm - 10:37 am

SAN

MYR

9h 22m

1 stop

5:30 pm - 11:35 pm

MYR

SAN

9h 05m

1 stop

$358Delta

Wed, Jun 3 - Tue, Jun 9

12:33 pm - 11:46 am

SAN

MYR

20h 13m

1 stop

2:28 pm - 5:59 pm

MYR

SAN

30h 31m

2 stops

$387Multiple Airlines

Fri, May 15 - Mon, May 18

American Airlines flights from San Diego to South Carolina

Our best American Airlines deals on San Diego to South Carolina flight tickets

American Airlines

May 12

SAN1:03 pmSan Diego

6h 59m

1 stop

GSP11:02 pmGreenville

May 19

GSP5:12 pmGreenville

7h 48m

1 stop

SAN10:00 pmSan Diego

$299

American Airlines

Apr 21

SAN1:03 pmSan Diego

6h 33m

1 stop

CHS10:36 pmCharleston

Apr 28

CHS6:00 amCharleston

8h 53m

1 stop

SAN11:53 amSan Diego

$305

American Airlines

Apr 29

SAN1:36 pmSan Diego

7h 22m

1 stop

SAV11:58 pmSavannah/Hilton Head

May 13

SAV7:45 pmSavannah/Hilton Head

7h 11m

1 stop

SAN11:56 pmSan Diego

$311

Frontier flights from San Diego to South Carolina

Our best Frontier deals on San Diego to South Carolina flight tickets

Frontier

May 15

SAN6:25 amSan Diego

28h 14m

1 stop

CLT1:39 pmCharlotte Douglas

May 24

CLT7:58 pmCharlotte Douglas

52h 14m

2 stops

SAN9:12 pmSan Diego

$389

Frontier

May 8

SAN6:25 amSan Diego

28h 14m

1 stop

CLT1:39 pmCharlotte Douglas

May 15

CLT7:23 pmCharlotte Douglas

26h 02m

1 stop

SAN6:25 pmSan Diego

$390

Frontier

Apr 19

SAN7:20 amSan Diego

24h 06m

1 stop

CLT10:26 amCharlotte Douglas

Apr 22

CLT7:49 pmCharlotte Douglas

15h 45m

1 stop

SAN8:34 amSan Diego

$391

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 5/12

1:03 pm-11:02 pm

1 stop6h 59m

Greenville

Tue 5/19

5:12 pm-10:00 pm

1 stop7h 48m

$299

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Tue 4/28

8:45 am-7:33 pm

1 stop7h 48m

Charleston

Wed 5/6

5:07 pm-9:25 pm

1 stop7h 18m

$300

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 5/12

10:20 am-9:40 pm

2 stops8h 20m

Greenville

Tue 5/19

5:05 pm-9:20 pm

1 stop7h 15m

$304

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Tue 6/2

6:45 am-8:00 pm

2 stops10h 15m

Charleston

Tue 6/9

4:15 pm-10:50 pm

2 stops9h 35m

$315

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Sat 4/25

9:15 pm-10:28 am

1 stop10h 13m

Charleston

Sat 5/2

11:09 am-8:04 pm

1 stop11h 55m

$334

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Tue 4/28

9:45 pm-9:27 am

1 stop8h 42m

Savannah/Hilton Head

Wed 5/6

4:59 pm-9:20 pm

1 stop7h 21m

$339

San DiegoMyrtle Beach

SAN - MYR

SANMYR

San Diego

Fri 5/15

12:33 pm-11:46 am

1 stop20h 13m

Myrtle Beach Intl

Mon 5/18

6:14 pm-5:59 pm

2 stops26h 45m

$340

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Sat 5/2

9:15 pm-9:52 am

1 stop9h 37m

Savannah/Hilton Head

Fri 5/8

10:41 am-8:00 pm

1 stop12h 19m

$343

San DiegoMyrtle Beach

SAN - MYR

SANMYR

San Diego

Wed 6/3

10:15 pm-10:37 am

1 stop9h 22m

Myrtle Beach Intl

Tue 6/9

5:30 pm-11:35 pm

1 stop9h 05m

$358

San DiegoMyrtle Beach

SAN - MYR

SANMYR

San Diego

Fri 5/15

12:33 pm-11:46 am

1 stop20h 13m

Myrtle Beach Intl

Mon 5/18

2:28 pm-5:59 pm

2 stops30h 31m

$387

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from San Diego is in January. Flight prices, which tend to average around $358, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from San Diego during September instead. Flights to South Carolina in September, while not as cheap as those in January, still average around $385.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $430 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from San Diego for as low as $335 on momondo.

Can stopping save me money on San Diego to South Carolina flights?

You could potentially save up to 9% on your flight if you consider stops on a San Diego to South Carolina flight.

Cheap San Diego to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to South Carolina

Fastest flight time	4h 35m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from San Diego to South Carolina takes 4h 35m

Direct flights go from San Diego to South Carolina every day.

There are 57 airports in South Carolina. From San Diego there are direct flights to Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from San Diego Airport to South Carolina?
Prices for flights from San Diego Airport to South Carolina refresh daily.
How many operators does momondo search for flights from San Diego Airport to South Carolina?
As of March 2026, there are 8 operators available to choose from for flights from San Diego Airport to South Carolina.
How old do you have to be to fly from San Diego Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Diego to South Carolina

Compare and see reviews for airlines that fly from San Diego to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $126	Free Cancellation	Rating 7.2 2,907 reviews	Search JetBlue flights
United Airlines	PriceFrom $233	Free Cancellation	Rating 7.4 9,491 reviews	Search United Airlines flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,507 reviews	Search American Airlines flights
Delta	PriceFrom $264	Free Cancellation	Rating 7.9 8,340 reviews	Search Delta flights
Southwest	PriceFrom $363	Free Cancellation	Rating 8.0 4,331 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to South Carolina?

Once all potential San Diego to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.