Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from San Diego to South Carolina from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to South Carolina departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Diego to South Carolina

Cheap round-trip flights

JetBlue Logo
8:55 pm - 11:19 amSAN-CHS
11h 24m1 stop
JetBlue Logo
9:30 am - 8:08 pmCHS-SAN
13h 38m1 stop
$275JetBlue
Find Deal
Wed, Feb 25 - Tue, Mar 3
Frontier Logo
6:27 pm - 11:22 amSAN-CLT
13h 55m1 stop
Frontier Logo
5:20 pm - 11:53 pmCLT-SAN
9h 33m1 stop
$285Frontier
Find Deal
Thu, Oct 2 - Mon, Oct 6
United Airlines Logo
10:51 am - 9:33 pmSAN-SAV
7h 42m1 stop
United Airlines Logo
10:00 am - 5:28 pmSAV-SAN
10h 28m2 stops
$302United Airlines
Find Deal
Tue, Nov 4 - Tue, Nov 11
Delta Logo
12:00 pm - 11:58 pmSAN-SAV
8h 58m1 stop
Delta Logo
6:59 pm - 11:14 pmSAV-SAN
7h 15m1 stop
$307Delta
Find Deal
Wed, Oct 22 - Mon, Oct 27
American Airlines Logo
6:17 am - 5:34 pmSAN-HHH
8h 17m1 stop
American Airlines Logo
11:04 am - 6:32 pmHHH-SAN
10h 28m1 stop
$309American Airlines
Find Deal
Tue, Mar 10 - Tue, Mar 17
Delta Logo
8:00 am - 6:59 pmSAN-CAE
7h 59m1 stop
Delta Logo
11:03 am - 3:31 pmCAE-SAN
7h 28m1 stop
$309Delta
Find Deal
Wed, Nov 12 - Wed, Nov 19
American Airlines Logo
7:52 pm - 10:24 amSAN-HHH
11h 32m2 stops
American Airlines Logo
11:04 am - 6:32 pmHHH-SAN
10h 28m1 stop
$314American Airlines
Find Deal
Tue, Mar 10 - Tue, Mar 17
Southwest Logo
6:50 am - 8:20 pmSAN-SAV
10h 30m1 stop
Southwest Logo
7:00 pm - 11:25 pmSAV-SAN
7h 25m1 stop
$317Southwest
Find Deal
Thu, Dec 4 - Mon, Dec 8
Southwest Logo
6:50 am - 8:20 pmSAN-SAV
10h 30m1 stop
Southwest Logo
1:20 pm - 9:10 pmSAV-SAN
10h 50m2 stops
$322Southwest
Find Deal
Thu, Dec 4 - Mon, Dec 8
United Airlines Logo
10:15 am - 9:54 pmSAN-SAV
8h 39m1 stop
United Airlines Logo
1:24 pm - 7:52 pmSAV-SAN
9h 28m2 stops
$355United Airlines
Find Deal
Wed, Oct 22 - Mon, Oct 27

Delta flights from San Diego to South Carolina

Our best Delta deals on San Diego to South Carolina flight tickets
Delta
Oct 22
SAN12:00 pmSan Diego
8h 58m
1 stop
SAV11:58 pmSavannah/Hilton Head
Oct 27
SAV6:59 pmSavannah/Hilton Head
7h 15m
1 stop
SAN11:14 pmSan Diego
$307
Find similar
Delta
Nov 12
SAN8:00 amSan Diego
7h 59m
1 stop
CAE6:59 pmColumbia Metropolitan
Nov 19
CAE11:03 amColumbia Metropolitan
7h 28m
1 stop
SAN3:31 pmSan Diego
$309
Find similar
Delta
Nov 5
SAN12:00 pmSan Diego
8h 43m
1 stop
SAV11:43 pmSavannah/Hilton Head
Nov 8
SAV5:44 pmSavannah/Hilton Head
8h 30m
1 stop
SAN11:14 pmSan Diego
$316
Find similar

Frontier flights from San Diego to South Carolina

Our best Frontier deals on San Diego to South Carolina flight tickets
Frontier
Oct 2
SAN6:27 pmSan Diego
13h 55m
1 stop
CLT11:22 amCharlotte Douglas
Oct 6
CLT5:20 pmCharlotte Douglas
9h 33m
1 stop
SAN11:53 pmSan Diego
$285
Find similar
Frontier
Oct 6
SAN6:35 amSan Diego
11h 50m
2 stops
CLT9:25 pmCharlotte Douglas
Oct 10
CLT5:34 pmCharlotte Douglas
9h 16m
1 stop
SAN11:50 pmSan Diego
$294
Find similar
Frontier
Oct 20
SAN6:41 amSan Diego
6h 58m
1 stop
CLT4:39 pmCharlotte Douglas
Oct 27
CLT5:34 pmCharlotte Douglas
22h 54m
1 stop
SAN1:28 pmSan Diego
$303
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Wed 2/25

8:55 pm-11:19 am

1 stop11h 24m

Charleston

Tue 3/3

9:30 am-8:08 pm

1 stop13h 38m

$275

San DiegoCharlotte

SAN - CLT

SANCLT

San Diego

Thu 10/2

6:27 pm-11:22 am

1 stop13h 55m

Charlotte Douglas

Mon 10/6

5:20 pm-11:53 pm

1 stop9h 33m

$285

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Tue 11/4

10:51 am-9:33 pm

1 stop7h 42m

Savannah/Hilton Head

Tue 11/11

10:00 am-5:28 pm

2 stops10h 28m

$302

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Wed 10/22

12:00 pm-11:58 pm

1 stop8h 58m

Savannah/Hilton Head

Mon 10/27

6:59 pm-11:14 pm

1 stop7h 15m

$307

San DiegoHilton Head Island

SAN - HHH

SANHHH

San Diego

Tue 3/10

6:17 am-5:34 pm

1 stop8h 17m

Hilton Head Island

Tue 3/17

11:04 am-6:32 pm

1 stop10h 28m

$309

San DiegoColumbia

SAN - CAE

SANCAE

San Diego

Wed 11/12

8:00 am-6:59 pm

1 stop7h 59m

Columbia Metropolitan

Wed 11/19

11:03 am-3:31 pm

1 stop7h 28m

$309

San DiegoHilton Head Island

SAN - HHH

SANHHH

San Diego

Tue 3/10

7:52 pm-10:24 am

2 stops11h 32m

Hilton Head Island

Tue 3/17

11:04 am-6:32 pm

1 stop10h 28m

$314

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Thu 12/4

6:50 am-8:20 pm

1 stop10h 30m

Savannah/Hilton Head

Mon 12/8

7:00 pm-11:25 pm

1 stop7h 25m

$317

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Thu 12/4

6:50 am-8:20 pm

1 stop10h 30m

Savannah/Hilton Head

Mon 12/8

1:20 pm-9:10 pm

2 stops10h 50m

$322

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Wed 10/22

10:15 am-9:54 pm

1 stop8h 39m

Savannah/Hilton Head

Mon 10/27

1:24 pm-7:52 pm

2 stops9h 28m

$355

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to South Carolina from

How to get the cheapest flight ticket from San Diego to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from San Diego is in January. Flight prices, which tend to average around $384, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from San Diego during April instead. Flights to South Carolina in April, while not as cheap as those in January, still average around $408.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $447. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $518.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest San Diego to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $279. Try not to purchase tickets in the morning because they tend to be around $494. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $449 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from San Diego for as low as $324 on momondo.

Can stopping save me money on San Diego to South Carolina flights?

You could potentially save up to 28% on your flight if you consider stops on a San Diego to South Carolina flight.

Cheap San Diego to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to South Carolina

Fastest flight time

4h 32m

Direct flights

Every day

Airports in South Carolina

1 airport
The fastest flight from San Diego to South Carolina takes 4h 32m
Direct flights go from San Diego to South Carolina every day.
There is 1 airport near South Carolina: Charlotte Douglas (CLT)
Search flight deals

  • When did momondo last update prices for flights from San Diego Airport to South Carolina?

    Prices for flights from San Diego Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to South Carolina?

  • How old do you have to be to fly from San Diego Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Diego to South Carolina

Compare and see reviews for airlines that fly from San Diego to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $158Free CancellationRating
6.3
8,031 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
8,922 reviews
Search United Airlines flights
American AirlinesPriceFrom $270Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
7,971 reviews
Search Delta flights
SouthwestPriceFrom $362Free CancellationRating
8.0
4,244 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to South Carolina?

Once all potential San Diego to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 10/22
Wed 10/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $47
Flights to Los Angelesfrom $38
Flights to Miamifrom $58
Flights to Chicagofrom $60
Flights to Orlandofrom $39
Flights to Las Vegasfrom $39
Flights to San Franciscofrom $51
Flights to Washington, D.C.from $50
Flights to Bostonfrom $67
Flights to Atlantafrom $39
Flights to Dallasfrom $59
Flights to Seattlefrom $102