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Cheap flights from San Diego to South Carolina from $53

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to South Carolina departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Diego to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
9:15 pm - 9:52 am
SAN
-
SAV
9h 37m
1 stop
JetBlue Logo
10:42 am - 8:04 pm
SAV
-
SAN
12h 22m
1 stop
$273JetBlue
Fri, Apr 24 - Tue, Apr 28
United Airlines Logo
8:45 am - 9:10 pm
SAN
-
CHS
9h 25m
1 stop
United Airlines Logo
2:48 pm - 8:45 pm
CHS
-
SAN
8h 57m
1 stop
$276United Airlines
Tue, Mar 10 - Tue, Mar 17
American Airlines Logo
1:01 pm - 11:59 pm
SAN
-
CHS
7h 58m
1 stop
American Airlines Logo
6:10 am - 10:57 am
CHS
-
SAN
7h 47m
1 stop
$299American Airlines
Wed, Mar 18 - Tue, Mar 24
Southwest Logo
1:30 pm - 10:25 pm
SAN
-
CHS
5h 55m
1 stop
Southwest Logo
12:50 pm - 7:30 pm
CHS
-
SAN
9h 40m
1 stop
$316Southwest
Wed, Mar 18 - Wed, Mar 25
Delta Logo
9:45 pm - 8:43 am
SAN
-
CHS
7h 58m
1 stop
Delta Logo
5:15 am - 11:24 am
CHS
-
SAN
9h 09m
1 stop
$320Delta
Wed, May 6 - Sun, May 10
American Airlines Logo
7:15 am - 6:45 pm
SAN
-
SAV
8h 30m
1 stop
American Airlines Logo
7:00 am - 2:05 pm
SAV
-
SAN
10h 05m
1 stop
$323American Airlines
Wed, Apr 29 - Wed, May 13
Delta Logo
10:20 pm - 9:28 am
SAN
-
CAE
8h 08m
1 stop
Delta Logo
5:07 pm - 10:48 pm
CAE
-
SAN
8h 41m
1 stop
$329Delta
Sat, Feb 28 - Sat, Mar 7
Southwest Logo
6:40 am - 8:30 pm
SAN
-
CHS
10h 50m
2 stops
Southwest Logo
12:50 pm - 7:30 pm
CHS
-
SAN
9h 40m
1 stop
$331Southwest
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
9:10 pm - 10:57 am
SAN
-
CHS
10h 47m
1 stop
Multiple Airlines Logo
6:32 pm - 10:04 am
CHS
-
SAN
18h 32m
1 stop
$336Multiple Airlines
Sun, Mar 1 - Sun, Mar 8
Multiple Airlines Logo
6:55 am - 10:12 am
SAN
-
CLT
48h 17m
2 stops
Multiple Airlines Logo
7:49 pm - 12:02 am
CLT
-
SAN
31h 13m
1 stop
$379Multiple Airlines
Sat, Mar 28 - Tue, Apr 7

Frontier flights from San Diego to South Carolina

Our best Frontier deals on San Diego to South Carolina flight tickets
Frontier
Feb 16
SAN6:25 amSan Diego
6h 53m
1 stop
CLT4:18 pmCharlotte Douglas
Feb 20
CLT7:42 pmCharlotte Douglas
7h 26m
1 stop
SAN12:08 amSan Diego
$375
Frontier
Feb 14
SAN12:23 pmSan Diego
24h 55m
1 stop
CLT4:18 pmCharlotte Douglas
Feb 16
CLT5:13 pmCharlotte Douglas
9h 55m
1 stop
SAN12:08 amSan Diego
$380
Frontier
Feb 5
SAN11:49 amSan Diego
25h 29m
1 stop
CLT4:18 pmCharlotte Douglas
Feb 12
CLT5:13 pmCharlotte Douglas
9h 55m
1 stop
SAN12:08 amSan Diego
$381

American Airlines flights from San Diego to South Carolina

Our best American Airlines deals on San Diego to South Carolina flight tickets
American Airlines
Mar 18
SAN1:01 pmSan Diego
7h 58m
1 stop
CHS11:59 pmCharleston
Mar 24
CHS6:10 amCharleston
7h 47m
1 stop
SAN10:57 amSan Diego
$299
American Airlines
Apr 22
SAN1:36 pmSan Diego
7h 23m
1 stop
CHS11:59 pmCharleston
Apr 25
CHS7:30 pmCharleston
7h 26m
1 stop
SAN11:56 pmSan Diego
$312
American Airlines
Apr 29
SAN7:15 amSan Diego
8h 30m
1 stop
SAV6:45 pmSavannah/Hilton Head
May 13
SAV7:00 amSavannah/Hilton Head
10h 05m
1 stop
SAN2:05 pmSan Diego
$323

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Fri 4/24

9:15 pm-9:52 am

1 stop9h 37m

Savannah/Hilton Head

Tue 4/28

10:42 am-8:04 pm

1 stop12h 22m

$273

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Tue 3/10

8:45 am-9:10 pm

1 stop9h 25m

Charleston

Tue 3/17

2:48 pm-8:45 pm

1 stop8h 57m

$276

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Wed 3/18

1:01 pm-11:59 pm

1 stop7h 58m

Charleston

Tue 3/24

6:10 am-10:57 am

1 stop7h 47m

$299

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Wed 3/18

1:30 pm-10:25 pm

1 stop5h 55m

Charleston

Wed 3/25

12:50 pm-7:30 pm

1 stop9h 40m

$316

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Wed 5/6

9:45 pm-8:43 am

1 stop7h 58m

Charleston

Sun 5/10

5:15 am-11:24 am

1 stop9h 09m

$320

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Wed 4/29

7:15 am-6:45 pm

1 stop8h 30m

Savannah/Hilton Head

Wed 5/13

7:00 am-2:05 pm

1 stop10h 05m

$323

San DiegoColumbia

SAN - CAE

SANCAE

San Diego

Sat 2/28

10:20 pm-9:28 am

1 stop8h 08m

Columbia Metropolitan

Sat 3/7

5:07 pm-10:48 pm

1 stop8h 41m

$329

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Wed 3/18

6:40 am-8:30 pm

2 stops10h 50m

Charleston

Wed 3/25

12:50 pm-7:30 pm

1 stop9h 40m

$331

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Sun 3/1

9:10 pm-10:57 am

1 stop10h 47m

Charleston

Sun 3/8

6:32 pm-10:04 am

1 stop18h 32m

$336

San DiegoCharlotte

SAN - CLT

SANCLT

San Diego

Sat 3/28

6:55 am-10:12 am

2 stops48h 17m

Charlotte Douglas

Tue 4/7

7:49 pm-12:02 am

1 stop31h 13m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from San Diego to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from San Diego is in January. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from San Diego during September instead. Flights to South Carolina in September, while not as cheap as those in January, still average around $385.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $432 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from San Diego for as low as $335 on momondo.

Can stopping save me money on San Diego to South Carolina flights?

You could potentially save up to 18% on your flight if you consider stops on a San Diego to South Carolina flight.

Cheap San Diego to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to South Carolina

Fastest flight time

4h 36m

Direct flights

Every day

Airports in South Carolina

57 airports
The fastest flight from San Diego to South Carolina takes 4h 36m
Direct flights go from San Diego to South Carolina every day.
There are 57 airports in South Carolina. From San Diego there are direct flights to Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from San Diego Airport to South Carolina?

    Prices for flights from San Diego Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to South Carolina?

  • How old do you have to be to fly from San Diego Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Diego to South Carolina

Compare and see reviews for airlines that fly from San Diego to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $126Free CancellationRating
7.2
2,892 reviews
Search JetBlue flights
DeltaPriceFrom $175Free CancellationRating
7.9
8,128 reviews
Search Delta flights
United AirlinesPriceFrom $199Free CancellationRating
7.4
9,226 reviews
Search United Airlines flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,210 reviews
Search American Airlines flights
SouthwestPriceFrom $344Free CancellationRating
8.0
4,272 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to South Carolina?

Once all potential San Diego to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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