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Cheap flights from San Diego to Panama City from $200

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 4/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:04 pm - 9:58 pm
SAN
-
ECP
5h 54m
1 stop
American Airlines Logo
11:43 am - 8:09 pm
ECP
-
SAN
10h 26m
1 stop
$375American Airlines
Tue, Apr 7 - Tue, Apr 14
Southwest Logo
9:35 am - 5:45 pm
SAN
-
ECP
6h 10m
1 stop
Southwest Logo
5:00 pm - 11:10 pm
ECP
-
SAN
8h 10m
1 stop
$387Southwest
Wed, Apr 8 - Thu, Apr 16
United Airlines Logo
12:10 pm - 9:59 pm
SAN
-
ECP
7h 49m
1 stop
United Airlines Logo
6:30 am - 2:57 pm
ECP
-
SAN
10h 27m
2 stops
$392United Airlines
Wed, Apr 8 - Thu, Apr 16
United Airlines Logo
11:01 am - 9:59 pm
SAN
-
ECP
8h 58m
2 stops
United Airlines Logo
6:30 am - 2:57 pm
ECP
-
SAN
10h 27m
2 stops
$397United Airlines
Wed, Apr 8 - Thu, Apr 16
Southwest Logo
6:45 am - 8:45 pm
SAN
-
ECP
12h 00m
1 stop
Southwest Logo
6:25 pm - 11:15 pm
ECP
-
SAN
6h 50m
1 stop
$403Southwest
Wed, Apr 29 - Sat, May 9
Southwest Logo
6:20 am - 5:45 pm
SAN
-
ECP
9h 25m
2 stops
Southwest Logo
5:30 pm - 9:45 pm
ECP
-
SAN
6h 15m
1 stop
$413Southwest
Wed, Apr 29 - Sat, May 9
American Airlines Logo
1:55 pm - 10:36 pm
SAN
-
ECP
6h 41m
1 stop
American Airlines Logo
6:56 pm - 11:59 pm
ECP
-
SAN
7h 03m
1 stop
$416American Airlines
Mon, Jun 8 - Wed, Jun 10
American Airlines Logo
8:00 am - 6:17 pm
SAN
-
ECP
8h 17m
1 stop
American Airlines Logo
5:30 am - 10:39 am
ECP
-
SAN
7h 09m
1 stop
$427American Airlines
Tue, Aug 4 - Mon, Aug 10
Delta Logo
10:30 pm - 8:35 am
SAN
-
ECP
8h 05m
1 stop
Delta Logo
6:46 pm - 11:25 pm
ECP
-
SAN
6h 39m
1 stop
$428Delta
Fri, Apr 17 - Mon, Apr 20
United Airlines Logo
8:32 pm - 9:44 am
SAN
-
ECP
11h 12m
2 stops
United Airlines Logo
5:05 pm - 9:24 pm
ECP
-
SAN
6h 19m
1 stop
$432United Airlines
Mon, Jun 8 - Wed, Jun 10

Delta flights from San Diego to Panama City, Florida

Our best Delta deals on San Diego to Panama City, Florida flight tickets
Delta
Apr 17
SAN10:30 pmSan Diego
8h 05m
1 stop
ECP8:35 amPanama City NW Florida Beaches
Apr 20
ECP6:46 pmPanama City NW Florida Beaches
6h 39m
1 stop
SAN11:25 pmSan Diego
$428
Delta
Apr 17
SAN9:45 pmSan Diego
8h 50m
1 stop
ECP8:35 amPanama City NW Florida Beaches
Apr 20
ECP6:46 pmPanama City NW Florida Beaches
6h 39m
1 stop
SAN11:25 pmSan Diego
$448
Delta
Apr 17
SAN10:30 pmSan Diego
8h 05m
1 stop
ECP8:35 amPanama City NW Florida Beaches
Apr 20
ECP6:46 pmPanama City NW Florida Beaches
6h 39m
1 stop
SAN11:25 pmSan Diego
$457

Southwest flights from San Diego to Panama City, Florida

Our best Southwest deals on San Diego to Panama City, Florida flight tickets
Southwest
Apr 8
SAN9:35 amSan Diego
6h 10m
1 stop
ECP5:45 pmPanama City NW Florida Beaches
Apr 16
ECP5:00 pmPanama City NW Florida Beaches
8h 10m
1 stop
SAN11:10 pmSan Diego
$387
Southwest
Apr 29
SAN6:45 amSan Diego
12h 00m
1 stop
ECP8:45 pmPanama City NW Florida Beaches
May 9
ECP6:25 pmPanama City NW Florida Beaches
6h 50m
1 stop
SAN11:15 pmSan Diego
$403
Southwest
Apr 29
SAN6:20 amSan Diego
9h 25m
2 stops
ECP5:45 pmPanama City NW Florida Beaches
May 9
ECP5:30 pmPanama City NW Florida Beaches
6h 15m
1 stop
SAN9:45 pmSan Diego
$413

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from San Diego to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 4/7

2:04 pm-9:58 pm

1 stop5h 54m

Panama City NW Florida Beaches

Tue 4/14

11:43 am-8:09 pm

1 stop10h 26m

$375

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Wed 4/8

9:35 am-5:45 pm

1 stop6h 10m

Panama City NW Florida Beaches

Thu 4/16

5:00 pm-11:10 pm

1 stop8h 10m

$387

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Wed 4/8

12:10 pm-9:59 pm

1 stop7h 49m

Panama City NW Florida Beaches

Thu 4/16

6:30 am-2:57 pm

2 stops10h 27m

$392

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Wed 4/8

11:01 am-9:59 pm

2 stops8h 58m

Panama City NW Florida Beaches

Thu 4/16

6:30 am-2:57 pm

2 stops10h 27m

$397

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Wed 4/29

6:45 am-8:45 pm

1 stop12h 00m

Panama City NW Florida Beaches

Sat 5/9

6:25 pm-11:15 pm

1 stop6h 50m

$403

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Wed 4/29

6:20 am-5:45 pm

2 stops9h 25m

Panama City NW Florida Beaches

Sat 5/9

5:30 pm-9:45 pm

1 stop6h 15m

$413
Quickest round-trip

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Mon 6/8

1:55 pm-10:36 pm

1 stop6h 41m

Panama City NW Florida Beaches

Wed 6/10

6:56 pm-11:59 pm

1 stop7h 03m

$416

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 8/4

8:00 am-6:17 pm

1 stop8h 17m

Panama City NW Florida Beaches

Mon 8/10

5:30 am-10:39 am

1 stop7h 09m

$427

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 4/17

10:30 pm-8:35 am

1 stop8h 05m

Panama City NW Florida Beaches

Mon 4/20

6:46 pm-11:25 pm

1 stop6h 39m

$428

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Mon 6/8

8:32 pm-9:44 am

2 stops11h 12m

Panama City NW Florida Beaches

Wed 6/10

5:05 pm-9:24 pm

1 stop6h 19m

$432

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from San Diego is in January. Flight prices, which tend to average around $290, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from San Diego averaging around $379.

How have San Diego to Panama City, Florida flight prices changed over time?

As of March 2026, prices for San Diego to Panama City, Florida flights are approximately 86% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City, Florida (SAN to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City, Florida

Fastest flight time

5h 50m

Direct flights

None
The fastest flight from San Diego to Panama City, Florida takes 5h 50m
There are no direct flights from San Diego to Panama City, Florida. There are no popular flight routes from San Diego to Panama City, Florida.
Search flight deals

  • How far is San Diego to Panama City NW Florida Beaches by plane?

    San Diego and Panama City NW Florida Beaches are 1857.1 mi apart from one another. By plane, this route typically takes 5h 50m.

  • When did momondo last update prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Diego to Panama City, Florida?

Best airlines flying from San Diego to Panama City, Florida

Compare and see reviews for airlines that fly from San Diego to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $200Free CancellationRating
7.1
11,488 reviews
Search American Airlines flights
United AirlinesPriceFrom $236Free CancellationRating
7.4
9,452 reviews
Search United Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,312 reviews
Search Delta flights
SouthwestPriceFrom $366Free CancellationRating
8.0
4,325 reviews
Search Southwest flights

  • Southwest Flights From San Diego to Panama City, Florida

    Southwest flies from San Diego to Panama City, Florida around 1 time per week, with 4,325 momondo users rating the airline 8.0/10. The cheapest Southwest deal from San Diego to Panama City, Florida in the last 72 hours was $366 (round-trip), much lower than the average airfare cost of $451 for Southwest flights on this route.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Diego to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

All flight searches from San Diego to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Diego to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from San Diego. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from San Diego and alert you when they change.

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