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Cheap flights from San Diego to Panama City from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 12/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
8:05 am - 6:14 pm
SAN
-
ECP
8h 09m1 stop
Delta Logo
2:14 pm - 8:37 pm
ECP
-
SAN
8h 23m1 stop
$310Delta
Tue, Feb 3 - Wed, Feb 18
American Airlines Logo
10:09 am - 9:19 pm
SAN
-
ECP
9h 10m2 stops
American Airlines Logo
12:37 pm - 8:25 pm
ECP
-
SAN
9h 48m1 stop
$315American Airlines
Tue, Feb 3 - Wed, Feb 18
Delta Logo
2:20 pm - 10:40 pm
SAN
-
ECP
6h 20m1 stop
Delta Logo
2:14 pm - 8:37 pm
ECP
-
SAN
8h 23m1 stop
$323Delta
Mon, Feb 9 - Wed, Feb 18
American Airlines Logo
10:09 am - 9:19 pm
SAN
-
ECP
9h 10m2 stops
American Airlines Logo
3:32 pm - 8:25 pm
ECP
-
SAN
6h 53m1 stop
$359American Airlines
Tue, Feb 10 - Wed, Feb 18
American Airlines Logo
10:09 am - 9:19 pm
SAN
-
ECP
9h 10m2 stops
American Airlines Logo
12:37 pm - 9:37 pm
ECP
-
SAN
11h 00m2 stops
$369American Airlines
Tue, Feb 3 - Wed, Feb 18
American Airlines Logo
6:20 am - 2:54 pm
SAN
-
ECP
6h 34m1 stop
American Airlines Logo
12:37 pm - 9:37 pm
ECP
-
SAN
11h 00m2 stops
$377American Airlines
Mon, Feb 9 - Wed, Feb 18
American Airlines Logo
10:50 am - 9:19 pm
SAN
-
ECP
8h 29m1 stop
American Airlines Logo
3:27 pm - 8:41 pm
ECP
-
SAN
7h 14m1 stop
$411American Airlines
Mon, Jan 19 - Fri, Jan 23
American Airlines Logo
10:09 am - 9:19 pm
SAN
-
ECP
9h 10m2 stops
American Airlines Logo
12:37 pm - 9:37 pm
ECP
-
SAN
11h 00m2 stops
$413American Airlines
Tue, Feb 10 - Wed, Feb 18
American Airlines Logo
10:50 am - 9:19 pm
SAN
-
ECP
8h 29m1 stop
American Airlines Logo
12:03 pm - 9:58 pm
ECP
-
SAN
11h 55m2 stops
$416American Airlines
Mon, Jan 19 - Fri, Jan 23
American Airlines Logo
7:00 am - 5:33 pm
SAN
-
ECP
8h 33m1 stop
American Airlines Logo
3:27 pm - 8:41 pm
ECP
-
SAN
7h 14m1 stop
$437American Airlines
Mon, Jan 19 - Fri, Jan 23

American Airlines flights from San Diego to Panama City, Florida

Our best American Airlines deals on San Diego to Panama City, Florida flight tickets
American Airlines
Feb 3
SAN10:09 amSan Diego
9h 10m
2 stops
ECP9:19 pmPanama City NW Florida Beaches
Feb 18
ECP12:37 pmPanama City NW Florida Beaches
9h 48m
1 stop
SAN8:25 pmSan Diego
$315
Find similar
American Airlines
Feb 10
SAN10:09 amSan Diego
9h 10m
2 stops
ECP9:19 pmPanama City NW Florida Beaches
Feb 18
ECP3:32 pmPanama City NW Florida Beaches
6h 53m
1 stop
SAN8:25 pmSan Diego
$359
Find similar
American Airlines
Feb 3
SAN10:09 amSan Diego
9h 10m
2 stops
ECP9:19 pmPanama City NW Florida Beaches
Feb 18
ECP12:37 pmPanama City NW Florida Beaches
11h 00m
2 stops
SAN9:37 pmSan Diego
$369
Find similar

Delta flights from San Diego to Panama City, Florida

Our best Delta deals on San Diego to Panama City, Florida flight tickets
Delta
Feb 3
SAN8:05 amSan Diego
8h 09m
1 stop
ECP6:14 pmPanama City NW Florida Beaches
Feb 18
ECP2:14 pmPanama City NW Florida Beaches
8h 23m
1 stop
SAN8:37 pmSan Diego
$310
Find similar
Delta
Feb 9
SAN2:20 pmSan Diego
6h 20m
1 stop
ECP10:40 pmPanama City NW Florida Beaches
Feb 18
ECP2:14 pmPanama City NW Florida Beaches
8h 23m
1 stop
SAN8:37 pmSan Diego
$323
Find similar
Delta
Dec 24
SAN8:00 amSan Diego
8h 15m
1 stop
ECP6:15 pmPanama City NW Florida Beaches
Jan 1
ECP8:02 amPanama City NW Florida Beaches
9h 24m
1 stop
SAN3:26 pmSan Diego
$615
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from San Diego to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 2/3

8:05 am-6:14 pm

1 stop8h 09m

Panama City NW Florida Beaches

Wed 2/18

2:14 pm-8:37 pm

1 stop8h 23m

$310

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 2/3

10:09 am-9:19 pm

2 stops9h 10m

Panama City NW Florida Beaches

Wed 2/18

12:37 pm-8:25 pm

1 stop9h 48m

$315

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Mon 2/9

2:20 pm-10:40 pm

1 stop6h 20m

Panama City NW Florida Beaches

Wed 2/18

2:14 pm-8:37 pm

1 stop8h 23m

$323

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 2/10

10:09 am-9:19 pm

2 stops9h 10m

Panama City NW Florida Beaches

Wed 2/18

3:32 pm-8:25 pm

1 stop6h 53m

$359

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 2/3

10:09 am-9:19 pm

2 stops9h 10m

Panama City NW Florida Beaches

Wed 2/18

12:37 pm-9:37 pm

2 stops11h 00m

$369

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Mon 2/9

6:20 am-2:54 pm

1 stop6h 34m

Panama City NW Florida Beaches

Wed 2/18

12:37 pm-9:37 pm

2 stops11h 00m

$377

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Mon 1/19

10:50 am-9:19 pm

1 stop8h 29m

Panama City NW Florida Beaches

Fri 1/23

3:27 pm-8:41 pm

1 stop7h 14m

$411

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 2/10

10:09 am-9:19 pm

2 stops9h 10m

Panama City NW Florida Beaches

Wed 2/18

12:37 pm-9:37 pm

2 stops11h 00m

$413

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Mon 1/19

10:50 am-9:19 pm

1 stop8h 29m

Panama City NW Florida Beaches

Fri 1/23

12:03 pm-9:58 pm

2 stops11h 55m

$416

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Mon 1/19

7:00 am-5:33 pm

1 stop8h 33m

Panama City NW Florida Beaches

Fri 1/23

3:27 pm-8:41 pm

1 stop7h 14m

$437

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from San Diego is in January. Flight prices, which tend to average around $313, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from San Diego averaging around $379.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $430. On the other hand, Friday is the most expensive day to depart from San Diego because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $536.

How have San Diego to Panama City, Florida flight prices changed over time?

As of December 2025, prices for San Diego to Panama City, Florida flights are approximately 1% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City, Florida (SAN to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City, Florida

Fastest flight time

6h 08m

Direct flights

None
The fastest flight from San Diego to Panama City, Florida takes 6h 08m
There are no direct flights from San Diego to Panama City, Florida. There are no popular flight routes from San Diego to Panama City, Florida.
Search flight deals

  • How far is San Diego to Panama City NW Florida Beaches by plane?

    San Diego and Panama City NW Florida Beaches are 1857.1 mi apart from one another. By plane, this route typically takes 6h 08m.

  • When did momondo last update prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Diego to Panama City, Florida?

Best airlines flying from San Diego to Panama City, Florida

Compare and see reviews for airlines that fly from San Diego to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $236Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,008 reviews
Search Delta flights
American AirlinesPriceFrom $330Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
SouthwestPriceFrom $366Free CancellationRating
7.9
4,253 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Diego to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

All flight searches from San Diego to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Diego to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from San Diego. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from San Diego and alert you when they change.

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