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Cheap flights from San Diego to Panama City from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 12/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Delta Logo
10:40 pm - 8:20 amSAN-ECP
7h 40m1 stop
Delta Logo
4:10 pm - 11:11 pmECP-SAN
9h 01m1 stop
$377Delta
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Tue, Apr 7 - Wed, Apr 8
Southwest Logo
6:30 am - 3:05 pmSAN-ECP
6h 35m1 stop
Southwest Logo
3:40 pm - 10:20 pmECP-SAN
8h 40m1 stop
$418Southwest
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Fri, Feb 13 - Mon, Feb 16
Southwest Logo
6:30 am - 3:05 pmSAN-ECP
6h 35m1 stop
Southwest Logo
3:35 pm - 10:15 pmECP-SAN
8h 40m2 stops
$423Southwest
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Fri, Feb 13 - Mon, Feb 16
American Airlines Logo
4:59 pm - 12:16 pmSAN-ECP
17h 17m1 stop
American Airlines Logo
3:45 pm - 8:10 pmECP-SAN
6h 25m1 stop
$444American Airlines
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Fri, Feb 13 - Mon, Feb 16
Southwest Logo
9:10 pm - 9:25 amSAN-ECP
10h 15m2 stops
Southwest Logo
3:40 pm - 10:10 pmECP-SAN
8h 30m2 stops
$447Southwest
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Fri, Feb 13 - Mon, Feb 16
American Airlines Logo
4:59 pm - 2:02 pmSAN-ECP
19h 03m1 stop
American Airlines Logo
3:45 pm - 8:10 pmECP-SAN
6h 25m1 stop
$457American Airlines
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Fri, Feb 13 - Mon, Feb 16
United Airlines Logo
6:30 am - 8:06 pmSAN-ECP
11h 36m2 stops
United Airlines Logo
12:55 pm - 7:57 pmECP-SAN
9h 02m1 stop
$472United Airlines
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Tue, Apr 7 - Wed, Apr 8
United Airlines Logo
7:00 am - 8:06 pmSAN-ECP
11h 06m2 stops
United Airlines Logo
3:10 pm - 11:44 pmECP-SAN
10h 34m2 stops
$477United Airlines
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Tue, Apr 7 - Wed, Apr 8
Southwest Logo
8:35 am - 5:55 pmSAN-ECP
7h 20m1 stop
Southwest Logo
5:55 pm - 11:25 pmECP-SAN
7h 30m1 stop
$488Southwest
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Tue, Dec 23 - Mon, Dec 29
Delta Logo
10:30 pm - 8:19 amSAN-ECP
7h 49m1 stop
Delta Logo
1:32 pm - 9:13 pmECP-SAN
9h 41m1 stop
$517Delta
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Fri, Nov 7 - Tue, Nov 11

Delta flights from San Diego to Panama City, Florida

Our best Delta deals on San Diego to Panama City, Florida flight tickets
Delta
Apr 7
SAN10:40 pmSan Diego
7h 40m
1 stop
ECP8:20 amPanama City NW Florida Beaches
Apr 8
ECP4:10 pmPanama City NW Florida Beaches
9h 01m
1 stop
SAN11:11 pmSan Diego
$377
Find similar
Delta
Nov 7
SAN10:30 pmSan Diego
7h 49m
1 stop
ECP8:19 amPanama City NW Florida Beaches
Nov 11
ECP1:32 pmPanama City NW Florida Beaches
9h 41m
1 stop
SAN9:13 pmSan Diego
$517
Find similar
Delta
Nov 7
SAN12:00 pmSan Diego
9h 10m
1 stop
ECP11:10 pmPanama City NW Florida Beaches
Nov 11
ECP6:00 amPanama City NW Florida Beaches
9h 03m
1 stop
SAN1:03 pmSan Diego
$537
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American Airlines flights from San Diego to Panama City, Florida

Our best American Airlines deals on San Diego to Panama City, Florida flight tickets
American Airlines
Feb 13
SAN4:59 pmSan Diego
17h 17m
1 stop
ECP12:16 pmPanama City NW Florida Beaches
Feb 16
ECP3:45 pmPanama City NW Florida Beaches
6h 25m
1 stop
SAN8:10 pmSan Diego
$444
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American Airlines
Feb 13
SAN4:59 pmSan Diego
19h 03m
1 stop
ECP2:02 pmPanama City NW Florida Beaches
Feb 16
ECP3:45 pmPanama City NW Florida Beaches
8h 25m
1 stop
SAN10:10 pmSan Diego
$457
Find similar
American Airlines
Nov 7
SAN12:40 pmSan Diego
8h 35m
1 stop
ECP11:15 pmPanama City NW Florida Beaches
Nov 11
ECP6:47 amPanama City NW Florida Beaches
10h 29m
2 stops
SAN3:16 pmSan Diego
$522
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momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from San Diego to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 4/7

10:40 pm-8:20 am

1 stop7h 40m

Panama City NW Florida Beaches

Wed 4/8

4:10 pm-11:11 pm

1 stop9h 01m

$377

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 2/13

6:30 am-3:05 pm

1 stop6h 35m

Panama City NW Florida Beaches

Mon 2/16

3:40 pm-10:20 pm

1 stop8h 40m

$418

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 2/13

6:30 am-3:05 pm

1 stop6h 35m

Panama City NW Florida Beaches

Mon 2/16

3:35 pm-10:15 pm

2 stops8h 40m

$423

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 2/13

4:59 pm-12:16 pm

1 stop17h 17m

Panama City NW Florida Beaches

Mon 2/16

3:45 pm-8:10 pm

1 stop6h 25m

$444

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 2/13

9:10 pm-9:25 am

2 stops10h 15m

Panama City NW Florida Beaches

Mon 2/16

3:40 pm-10:10 pm

2 stops8h 30m

$447

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 2/13

4:59 pm-2:02 pm

1 stop19h 03m

Panama City NW Florida Beaches

Mon 2/16

3:45 pm-8:10 pm

1 stop6h 25m

$457

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 4/7

6:30 am-8:06 pm

2 stops11h 36m

Panama City NW Florida Beaches

Wed 4/8

12:55 pm-7:57 pm

1 stop9h 02m

$472

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 4/7

7:00 am-8:06 pm

2 stops11h 06m

Panama City NW Florida Beaches

Wed 4/8

3:10 pm-11:44 pm

2 stops10h 34m

$477

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 12/23

8:35 am-5:55 pm

1 stop7h 20m

Panama City NW Florida Beaches

Mon 12/29

5:55 pm-11:25 pm

1 stop7h 30m

$488

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 11/7

10:30 pm-8:19 am

1 stop7h 49m

Panama City NW Florida Beaches

Tue 11/11

1:32 pm-9:13 pm

1 stop9h 41m

$517

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from San Diego is in August. Flight prices, which tend to average around $379, are often lower during this time because this is during the off-season. The month of May is another great option to travel to Panama City, Florida, with average flight prices from San Diego averaging around $404.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $430. On the other hand, Friday is the most expensive day to depart from San Diego because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $536.

How have San Diego to Panama City, Florida flight prices changed over time?

As of October 2025, prices for San Diego to Panama City, Florida flights are approximately 44% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City, Florida (SAN to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City, Florida

Direct flights

None
There are no direct flights from San Diego to Panama City, Florida. There are no popular flight routes from San Diego to Panama City, Florida.
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  • How far is San Diego to Panama City NW Florida Beaches by plane?

    San Diego and Panama City NW Florida Beaches are 1857.1 mi apart from one another. By plane, this route typically takes 5h 56m.

  • When did momondo last update prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Diego to Panama City, Florida?

Best airlines flying from San Diego to Panama City, Florida

Compare and see reviews for airlines that fly from San Diego to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $236Free CancellationRating
7.4
8,995 reviews
Search United Airlines flights
DeltaPriceFrom $312Free CancellationRating
7.9
7,982 reviews
Search Delta flights
American AirlinesPriceFrom $330Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights
SouthwestPriceFrom $375Free CancellationRating
8.0
4,236 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Diego to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

All flight searches from San Diego to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Diego to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from San Diego. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from San Diego and alert you when they change.

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