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Cheap flights from San Diego to Panama City from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama City departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:35 pm - 2:24 pm
SAN
-
ECP
13h 49m
1 stop
American Airlines Logo
4:34 pm - 10:59 pm
ECP
-
SAN
8h 25m
1 stop
$357American Airlines
Tue, Mar 10 - Fri, Mar 13
Delta Logo
10:30 pm - 8:40 am
SAN
-
ECP
8h 10m
1 stop
Delta Logo
11:08 am - 6:51 pm
ECP
-
SAN
9h 43m
1 stop
$361Delta
Sun, Mar 15 - Mon, Mar 23
Southwest Logo
6:20 am - 4:25 pm
SAN
-
ECP
8h 05m
1 stop
Southwest Logo
3:30 pm - 10:30 pm
ECP
-
SAN
9h 00m
2 stops
$364Southwest
Wed, Mar 18 - Wed, Mar 25
United Airlines Logo
10:30 pm - 9:43 am
SAN
-
ECP
9h 13m
1 stop
United Airlines Logo
10:24 am - 7:48 pm
ECP
-
SAN
11h 24m
2 stops
$366United Airlines
Sun, Mar 8 - Thu, Mar 12
American Airlines Logo
10:35 pm - 12:21 pm
SAN
-
ECP
11h 46m
1 stop
American Airlines Logo
3:00 pm - 9:43 pm
ECP
-
SAN
8h 43m
1 stop
$367American Airlines
Fri, Feb 27 - Fri, Mar 6
United Airlines Logo
6:15 am - 4:18 pm
SAN
-
ECP
8h 03m
1 stop
United Airlines Logo
2:26 pm - 7:50 pm
ECP
-
SAN
7h 24m
1 stop
$368United Airlines
Tue, May 19 - Wed, May 27
United Airlines Logo
8:50 pm - 9:43 am
SAN
-
ECP
10h 53m
2 stops
United Airlines Logo
10:24 am - 7:48 pm
ECP
-
SAN
11h 24m
2 stops
$372United Airlines
Sun, Mar 8 - Thu, Mar 12
United Airlines Logo
6:26 pm - 9:47 am
SAN
-
ECP
13h 21m
2 stops
United Airlines Logo
6:30 am - 10:51 am
ECP
-
SAN
6h 21m
1 stop
$373United Airlines
Tue, May 19 - Wed, May 27
Southwest Logo
10:05 am - 8:45 pm
SAN
-
ECP
8h 40m
2 stops
Southwest Logo
7:55 am - 2:20 pm
ECP
-
SAN
8h 25m
2 stops
$378Southwest
Tue, May 19 - Wed, May 27
Southwest Logo
8:30 am - 8:00 pm
SAN
-
ECP
9h 30m
2 stops
Southwest Logo
1:45 pm - 10:30 pm
ECP
-
SAN
10h 45m
2 stops
$388Southwest
Wed, Mar 18 - Wed, Mar 25

Delta flights from San Diego to Panama City, Florida

Our best Delta deals on San Diego to Panama City, Florida flight tickets
Delta
Mar 15
SAN10:30 pmSan Diego
8h 10m
1 stop
ECP8:40 amPanama City NW Florida Beaches
Mar 23
ECP11:08 amPanama City NW Florida Beaches
9h 43m
1 stop
SAN6:51 pmSan Diego
$361
Delta
Mar 19
SAN9:55 pmSan Diego
8h 45m
1 stop
ECP8:40 amPanama City NW Florida Beaches
Mar 25
ECP5:30 pmPanama City NW Florida Beaches
7h 39m
1 stop
SAN11:09 pmSan Diego
$404
Delta
Mar 16
SAN3:45 pmSan Diego
14h 55m
2 stops
ECP8:40 amPanama City NW Florida Beaches
Mar 24
ECP11:08 amPanama City NW Florida Beaches
9h 43m
1 stop
SAN6:51 pmSan Diego
$440

Southwest flights from San Diego to Panama City, Florida

Our best Southwest deals on San Diego to Panama City, Florida flight tickets
Southwest
Mar 18
SAN6:20 amSan Diego
8h 05m
1 stop
ECP4:25 pmPanama City NW Florida Beaches
Mar 25
ECP3:30 pmPanama City NW Florida Beaches
9h 00m
2 stops
SAN10:30 pmSan Diego
$364
Southwest
May 19
SAN10:05 amSan Diego
8h 40m
2 stops
ECP8:45 pmPanama City NW Florida Beaches
May 27
ECP7:55 amPanama City NW Florida Beaches
8h 25m
2 stops
SAN2:20 pmSan Diego
$378
Southwest
Mar 18
SAN8:30 amSan Diego
9h 30m
2 stops
ECP8:00 pmPanama City NW Florida Beaches
Mar 25
ECP1:45 pmPanama City NW Florida Beaches
10h 45m
2 stops
SAN10:30 pmSan Diego
$388

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from San Diego to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 3/10

10:35 pm-2:24 pm

1 stop13h 49m

Panama City NW Florida Beaches

Fri 3/13

4:34 pm-10:59 pm

1 stop8h 25m

$357

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Sun 3/15

10:30 pm-8:40 am

1 stop8h 10m

Panama City NW Florida Beaches

Mon 3/23

11:08 am-6:51 pm

1 stop9h 43m

$361

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Wed 3/18

6:20 am-4:25 pm

1 stop8h 05m

Panama City NW Florida Beaches

Wed 3/25

3:30 pm-10:30 pm

2 stops9h 00m

$364

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Sun 3/8

10:30 pm-9:43 am

1 stop9h 13m

Panama City NW Florida Beaches

Thu 3/12

10:24 am-7:48 pm

2 stops11h 24m

$366

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Fri 2/27

10:35 pm-12:21 pm

1 stop11h 46m

Panama City NW Florida Beaches

Fri 3/6

3:00 pm-9:43 pm

1 stop8h 43m

$367

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 5/19

6:15 am-4:18 pm

1 stop8h 03m

Panama City NW Florida Beaches

Wed 5/27

2:26 pm-7:50 pm

1 stop7h 24m

$368

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Sun 3/8

8:50 pm-9:43 am

2 stops10h 53m

Panama City NW Florida Beaches

Thu 3/12

10:24 am-7:48 pm

2 stops11h 24m

$372

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 5/19

6:26 pm-9:47 am

2 stops13h 21m

Panama City NW Florida Beaches

Wed 5/27

6:30 am-10:51 am

1 stop6h 21m

$373

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Tue 5/19

10:05 am-8:45 pm

2 stops8h 40m

Panama City NW Florida Beaches

Wed 5/27

7:55 am-2:20 pm

2 stops8h 25m

$378

San DiegoPanama City

SAN - ECP

SANECP

San Diego

Wed 3/18

8:30 am-8:00 pm

2 stops9h 30m

Panama City NW Florida Beaches

Wed 3/25

1:45 pm-10:30 pm

2 stops10h 45m

$388

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from San Diego to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from San Diego is in January. Flight prices, which tend to average around $313, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from San Diego averaging around $379.

How have San Diego to Panama City, Florida flight prices changed over time?

As of January 2026, prices for San Diego to Panama City, Florida flights are approximately 1% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Panama City, Florida (SAN to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama City, Florida

Fastest flight time

6h 11m

Direct flights

None
The fastest flight from San Diego to Panama City, Florida takes 6h 11m
There are no direct flights from San Diego to Panama City, Florida. There are no popular flight routes from San Diego to Panama City, Florida.
Search flight deals

  • How far is San Diego to Panama City NW Florida Beaches by plane?

    San Diego and Panama City NW Florida Beaches are 1857.1 mi apart from one another. By plane, this route typically takes 6h 11m.

  • When did momondo last update prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from San Diego Airport to Panama City NW Florida Beaches Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from San Diego Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Diego to Panama City, Florida?

Best airlines flying from San Diego to Panama City, Florida

Compare and see reviews for airlines that fly from San Diego to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $236Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,128 reviews
Search Delta flights
American AirlinesPriceFrom $290Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights
SouthwestPriceFrom $359Free CancellationRating
8.0
4,267 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Diego to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from San Diego to Panama City with flexible booking policies on momondo?

All flight searches from San Diego to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Diego to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from San Diego. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Diego to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from San Diego and alert you when they change.

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