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Cheap flights from San Diego to Louisville from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Louisville departing on 8/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:32 pm - 3:26 pmSAN  San Diego-SDF Louisville Intl
15h 54m2 stops Denver Intl Raleigh-Durham
Multiple Airlines Logo
8:47 am - 7:37 pmSDF  Louisville Intl-SAN San Diego
13h 50m1 stop San Francisco
$291Multiple Airlines
Fri, Nov 13 - Mon, Nov 16
Multiple Airlines Logo
6:45 pm - 8:31 pmSAN  San Diego-SDF Louisville Intl
22h 46m2 stops Dallas/Fort Worth Raleigh-Durham
Multiple Airlines Logo
8:47 am - 6:19 pmSDF  Louisville Intl-SAN San Diego
12h 32m1 stop San Francisco
$307Multiple Airlines
Fri, Oct 2 - Mon, Oct 5
Southwest Logo
6:35 am - 5:30 pmSAN  San Diego-SDF Louisville Intl
7h 55m1 stop Chicago Midway
Southwest Logo
7:10 pm - 11:00 pmSDF  Louisville Intl-SAN San Diego
6h 50m1 stop Chicago Midway
$321Southwest
Sat, Sep 5 - Fri, Sep 11
American Airlines Logo
6:15 am - 6:35 pmSAN  San Diego-SDF Louisville Intl
9h 20m1 stop Chicago O'Hare Intl
American Airlines Logo
12:38 pm - 7:17 pmSDF  Louisville Intl-SAN San Diego
9h 39m1 stop Charlotte Douglas
$321American Airlines
Sat, Sep 5 - Fri, Sep 11
Southwest Logo
2:30 pm - 11:10 pmSAN  San Diego-SDF Louisville Intl
5h 40m1 stop Phoenix Sky Harbor Intl
Southwest Logo
4:55 pm - 8:25 pmSDF  Louisville Intl-SAN San Diego
6h 30m1 stop Chicago Midway
$326Southwest
Thu, Sep 10 - Sat, Sep 12
American Airlines Logo
10:06 am - 9:35 pmSAN  San Diego-SDF Louisville Intl
8h 29m1 stop Chicago O'Hare Intl
American Airlines Logo
5:04 am - 9:10 amSDF  Louisville Intl-SAN San Diego
7h 06m1 stop Charlotte Douglas
$326American Airlines
Tue, Oct 27 - Fri, Oct 30
Delta Logo
12:38 pm - 11:59 pmSAN  San Diego-SDF Louisville Intl
8h 21m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:55 am - 2:20 pmSDF  Louisville Intl-SAN San Diego
9h 25m1 stop Detroit Metropolitan Wayne County
$334Delta
Tue, Oct 27 - Fri, Oct 30
United Airlines Logo
12:33 pm - 10:31 pmSAN  San Diego-SDF Louisville Intl
6h 58m1 stop Denver Intl
United Airlines Logo
6:00 am - 11:17 amSDF  Louisville Intl-SAN San Diego
8h 17m1 stop Washington, D.C. Dulles Intl
$334United Airlines
Sat, Sep 5 - Mon, Sep 7
Delta Logo
11:48 am - 11:56 pmSAN  San Diego-SDF Louisville Intl
9h 08m1 stop Minneapolis St Paul
Delta Logo
6:00 am - 11:25 amSDF  Louisville Intl-SAN San Diego
8h 25m1 stop Atlanta Hartsfield-Jackson
$339Delta
Wed, Sep 2 - Wed, Sep 9
United Airlines Logo
10:30 pm - 9:34 amSAN  San Diego-SDF Louisville Intl
8h 04m1 stop Chicago O'Hare Intl
United Airlines Logo
5:15 am - 9:32 amSDF  Louisville Intl-SAN San Diego
7h 17m1 stop Chicago O'Hare Intl
$426United Airlines
Thu, Sep 24 - Mon, Sep 28

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Southwest flights from San Diego to Louisville

Our best Southwest deals on San Diego to Louisville flight tickets
Southwest
Sep 5
SAN6:35 amSan Diego
7h 55m
1 stop
SDF5:30 pmLouisville Intl
Sep 11
SDF7:10 pmLouisville Intl
6h 50m
1 stop
SAN11:00 pmSan Diego
$321
Southwest
Sep 5
SAN7:35 amSan Diego
10h 50m
1 stop
SDF9:25 pmLouisville Intl
Sep 11
SDF3:20 pmLouisville Intl
9h 40m
2 stops
SAN10:00 pmSan Diego
$326
Southwest
Sep 10
SAN2:30 pmSan Diego
5h 40m
1 stop
SDF11:10 pmLouisville Intl
Sep 12
SDF4:55 pmLouisville Intl
9h 20m
2 stops
SAN11:15 pmSan Diego
$332

American Airlines flights from San Diego to Louisville

Our best American Airlines deals on San Diego to Louisville flight tickets
American Airlines
Sep 9
SAN6:15 amSan Diego
6h 13m
1 stop
SDF3:28 pmLouisville Intl
Sep 12
SDF5:59 pmLouisville Intl
6h 49m
1 stop
SAN9:48 pmSan Diego
$331
American Airlines
Sep 26
SAN10:04 amSan Diego
9h 29m
1 stop
SDF10:33 pmLouisville Intl
Sep 29
SDF7:03 amLouisville Intl
8h 12m
1 stop
SAN12:15 pmSan Diego
$347
American Airlines
Sep 16
SAN10:46 pmSan Diego
7h 57m
1 stop
SDF9:43 amLouisville Intl
Sep 19
SDF2:47 pmLouisville Intl
9h 43m
1 stop
SAN9:30 pmSan Diego
$356

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from San Diego to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Fri 11/13

8:32 pm-3:26 pm

2 stops15h 54m

Louisville Intl

Mon 11/16

8:47 am-7:37 pm

1 stop13h 50m

$291

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Fri 10/2

6:45 pm-8:31 pm

2 stops22h 46m

Louisville Intl

Mon 10/5

8:47 am-6:19 pm

1 stop12h 32m

$307

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Sat 9/5

6:35 am-5:30 pm

1 stop7h 55m

Louisville Intl

Fri 9/11

7:10 pm-11:00 pm

1 stop6h 50m

$321

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Sat 9/5

6:15 am-6:35 pm

1 stop9h 20m

Louisville Intl

Fri 9/11

12:38 pm-7:17 pm

1 stop9h 39m

$321
Quickest round-trip

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Thu 9/10

2:30 pm-11:10 pm

1 stop5h 40m

Louisville Intl

Sat 9/12

4:55 pm-8:25 pm

1 stop6h 30m

$326

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Tue 10/27

10:06 am-9:35 pm

1 stop8h 29m

Louisville Intl

Fri 10/30

5:04 am-9:10 am

1 stop7h 06m

$326

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Tue 10/27

12:38 pm-11:59 pm

1 stop8h 21m

Louisville Intl

Fri 10/30

7:55 am-2:20 pm

1 stop9h 25m

$334

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Sat 9/5

12:33 pm-10:31 pm

1 stop6h 58m

Louisville Intl

Mon 9/7

6:00 am-11:17 am

1 stop8h 17m

$334

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Wed 9/2

11:48 am-11:56 pm

1 stop9h 08m

Louisville Intl

Wed 9/9

6:00 am-11:25 am

1 stop8h 25m

$339

San DiegoLouisville

SAN San Diego - SDF Louisville Intl

SANSDF

San Diego

Thu 9/24

10:30 pm-9:34 am

1 stop8h 04m

Louisville Intl

Mon 9/28

5:15 am-9:32 am

1 stop7h 17m

$426

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from San Diego to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Louisville?

Prices are currently low for flights on this route.

Typical prices usually range from $394 to $856.
The lowest price recently found on this route was $307.

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of April, then departing from San Diego during the month November is also very affordable. Most momondo users find prices during this month for around $393.

How have San Diego to Louisville flight prices changed over time?

As of August 2026, prices for San Diego to Louisville flights are approximately 45% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Louisville (SAN to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Louisville

Fastest flight time

6h 46m

Direct flights

None
The fastest flight from San Diego to Louisville takes 6h 46m
There are no direct flights from San Diego to Louisville. There are no popular flight routes from San Diego to Louisville.
Search flight deals

Frequently asked questions about flying from San Diego to Louisville

  • How far is San Diego to Louisville Intl by plane?

    A flight from San Diego to Louisville Intl will travel around 1797.3 mi. Typically, this will take 6h 46m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Louisville Intl Airport?

    Prices for flights from San Diego Airport to Louisville Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Diego Airport to Louisville Intl Airport?

  • How old do you have to be to fly from San Diego Airport to Louisville Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The required travel and health documents for your Louisville Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Louisville Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Louisville?

Best airlines flying from San Diego to Louisville

Compare and see reviews for airlines that fly from San Diego to Louisville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $246Free CancellationRating
7.1
11,865 reviews
Search American Airlines flights
SouthwestPriceFrom $255Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
DeltaPriceFrom $276Free CancellationRating
7.8
8,491 reviews
Search Delta flights
United AirlinesPriceFrom $280Free CancellationRating
7.4
10,072 reviews
Search United Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
Jeffersonville
West Baden Springs
Bardstown
New Albany
Shepherdsville
Elizabeth
Charlestown
Corydon
Brandenburg
Georgetown
Springfield

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Diego to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from San Diego to Louisville with flexible booking policies on momondo?

Flights from San Diego to Louisville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Diego to Louisville?

momondo helps you find the best flight between San Diego and Louisville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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