Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Portland to Des Moines from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Des Moines departing on 5/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Portland to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
5:14 pm - 7:14 pm
PDX
-
DSM
24h 00m
2 stops
Frontier Logo
8:14 pm - 1:02 pm
DSM
-
PDX
18h 48m
1 stop
$295Frontier
Sun, Apr 5 - Mon, Apr 13
Multiple Airlines Logo
8:26 pm - 8:55 pm
PDX
-
DSM
22h 29m
1 stop
Multiple Airlines Logo
8:14 pm - 1:02 pm
DSM
-
PDX
18h 48m
1 stop
$346Multiple Airlines
Sun, Apr 5 - Mon, Apr 13
United Airlines Logo
12:57 pm - 10:20 pm
PDX
-
DSM
7h 23m
1 stop
United Airlines Logo
3:24 pm - 10:56 pm
DSM
-
PDX
9h 32m
1 stop
$357United Airlines
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
1:40 pm - 11:43 pm
PDX
-
DSM
8h 03m
2 stops
United Airlines Logo
3:24 pm - 10:56 pm
DSM
-
PDX
9h 32m
1 stop
$362United Airlines
Tue, Feb 24 - Sat, Feb 28
American Airlines Logo
11:35 pm - 9:01 am
PDX
-
DSM
7h 26m
1 stop
American Airlines Logo
7:44 pm - 10:58 am
DSM
-
PDX
17h 14m
1 stop
$367American Airlines
Thu, Feb 19 - Tue, Feb 24
American Airlines Logo
8:00 am - 11:29 pm
PDX
-
DSM
13h 29m
1 stop
American Airlines Logo
11:58 am - 10:32 pm
DSM
-
PDX
12h 34m
1 stop
$375American Airlines
Wed, Apr 22 - Fri, May 1
Delta Logo
12:30 am - 10:09 am
PDX
-
DSM
7h 39m
1 stop
Delta Logo
4:25 pm - 8:25 pm
DSM
-
PDX
6h 00m
1 stop
$377Delta
Mon, Apr 6 - Tue, Apr 7
American Airlines Logo
11:35 pm - 1:05 pm
PDX
-
DSM
11h 30m
1 stop
American Airlines Logo
7:44 pm - 10:58 am
DSM
-
PDX
17h 14m
1 stop
$385American Airlines
Fri, Feb 20 - Sun, Feb 22
American Airlines Logo
2:43 pm - 9:01 am
PDX
-
DSM
16h 18m
1 stop
American Airlines Logo
7:44 pm - 10:58 am
DSM
-
PDX
17h 14m
1 stop
$397American Airlines
Wed, Feb 11 - Mon, Feb 16
Delta Logo
11:15 pm - 9:46 am
PDX
-
DSM
8h 31m
1 stop
Delta Logo
10:51 am - 5:39 pm
DSM
-
PDX
8h 48m
1 stop
$402Delta
Mon, Apr 6 - Wed, Apr 8

Delta flights from Portland to Des Moines

Our best Delta deals on Portland to Des Moines flight tickets
Delta
Apr 6
PDX11:15 pmPortland
8h 31m
1 stop
DSM9:46 amDes Moines
Apr 7
DSM4:25 pmDes Moines
6h 00m
1 stop
PDX8:25 pmPortland
$402
Delta
Apr 4
PDX11:15 pmPortland
8h 31m
1 stop
DSM9:46 amDes Moines
Apr 11
DSM4:25 pmDes Moines
6h 00m
1 stop
PDX8:25 pmPortland
$418
Delta
Apr 4
PDX12:30 amPortland
7h 39m
1 stop
DSM10:09 amDes Moines
Apr 11
DSM4:25 pmDes Moines
6h 00m
1 stop
PDX8:25 pmPortland
$422

American Airlines flights from Portland to Des Moines

Our best American Airlines deals on Portland to Des Moines flight tickets
American Airlines
Feb 19
PDX11:40 pmPortland
8h 54m
1 stop
DSM10:34 amDes Moines
Feb 24
DSM1:38 pmDes Moines
12h 39m
1 stop
PDX12:17 amPortland
$360
American Airlines
Feb 19
PDX11:35 pmPortland
7h 26m
1 stop
DSM9:01 amDes Moines
Feb 24
DSM7:44 pmDes Moines
17h 14m
1 stop
PDX10:58 amPortland
$367
American Airlines
Apr 22
PDX8:00 amPortland
13h 29m
1 stop
DSM11:29 pmDes Moines
May 1
DSM11:58 amDes Moines
12h 34m
1 stop
PDX10:32 pmPortland
$375

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Sun 4/5

5:14 pm-7:14 pm

2 stops24h 00m

Des Moines

Mon 4/13

8:14 pm-1:02 pm

1 stop18h 48m

$295

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Sun 4/5

8:26 pm-8:55 pm

1 stop22h 29m

Des Moines

Mon 4/13

8:14 pm-1:02 pm

1 stop18h 48m

$346

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Tue 2/24

12:57 pm-10:20 pm

1 stop7h 23m

Des Moines

Sat 2/28

3:24 pm-10:56 pm

1 stop9h 32m

$357

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Tue 2/24

1:40 pm-11:43 pm

2 stops8h 03m

Des Moines

Sat 2/28

3:24 pm-10:56 pm

1 stop9h 32m

$362

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 2/19

11:35 pm-9:01 am

1 stop7h 26m

Des Moines

Tue 2/24

7:44 pm-10:58 am

1 stop17h 14m

$367

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 4/22

8:00 am-11:29 pm

1 stop13h 29m

Des Moines

Fri 5/1

11:58 am-10:32 pm

1 stop12h 34m

$375

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Mon 4/6

12:30 am-10:09 am

1 stop7h 39m

Des Moines

Tue 4/7

4:25 pm-8:25 pm

1 stop6h 00m

$377

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Fri 2/20

11:35 pm-1:05 pm

1 stop11h 30m

Des Moines

Sun 2/22

7:44 pm-10:58 am

1 stop17h 14m

$385

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 2/11

2:43 pm-9:01 am

1 stop16h 18m

Des Moines

Mon 2/16

7:44 pm-10:58 am

1 stop17h 14m

$397

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Mon 4/6

11:15 pm-9:46 am

1 stop8h 31m

Des Moines

Wed 4/8

10:51 am-5:39 pm

1 stop8h 48m

$402

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Portland to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then July is your next best option. Flight prices from Portland to Des Moines during July average around $259.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Portland to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $193. Flights from Portland to Des Moines on a Sunday will generally be more expensive and average around $212. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Portland to Des Moines in the morning for as low as $142. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $220. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Portland to Des Moines flight route?

Fly from Portland to Des Moines for the best Portland - Des Moines flight prices

How far in advance should I book a flight to Des Moines?

You are more likely to see cheaper flights to Des Moines from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $343 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Portland for as low as $210 on momondo.

What cabin class options are available on Portland to Des Moines flights?

There is only 1 cabin class available to choose from on Portland to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Portland to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Portland to Des Moines.

How have Portland to Des Moines flight prices changed over time?

As of January 2026, prices for Portland to Des Moines flights are approximately 35% cheaper when compared to flights at the same time last year.

When to book flights from Portland to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Des Moines (PDX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Des Moines

Fastest flight time

3h 21m

Direct flights

Mon, Wed and Fri

Airports in Des Moines

1 airport
The fastest flight from Portland to Des Moines takes 3h 21m
Direct flights go from Portland to Des Moines on Monday, Wednesday and Friday. There are no airlines offering direct flights.
There is 1 airport in Des Moines. From Portland there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is Portland to Des Moines by plane?

    There are 1470.3 mi between Portland and Des Moines. 3h 21m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

    Prices for flights from Portland Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

  • How old do you have to be to fly from Portland Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Portland to Des Moines?

  • What is the most popular airline from Portland to Des Moines?

Best airlines flying from Portland to Des Moines

Compare and see reviews for airlines that fly from Portland to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $81Free CancellationRating
7.2
706 reviews
Search Allegiant Air flights
FrontierPriceFrom $140Free CancellationRating
5.7
3,056 reviews
Search Frontier flights
DeltaPriceFrom $143Free CancellationRating
7.9
8,119 reviews
Search Delta flights
United AirlinesPriceFrom $251Free CancellationRating
7.4
9,205 reviews
Search United Airlines flights
American AirlinesPriceFrom $261Free CancellationRating
7.2
11,197 reviews
Search American Airlines flights
SouthwestPriceFrom $364Free CancellationRating
8.0
4,268 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Des Moines.

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 2/26
Thu 3/5
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States