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Cheap flights from Portland to Des Moines from $99

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Des Moines departing on 5/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Portland to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 3:40 pm
PDX
-
DSM
7h 40m
1 stop
Delta Logo
6:50 am - 12:44 pm
DSM
-
PDX
7h 54m
1 stop
$357Delta
Wed, Feb 25 - Sat, Feb 28
Multiple Airlines Logo
11:28 am - 3:40 pm
PDX
-
DSM
26h 12m
1 stop
Multiple Airlines Logo
8:30 am - 11:18 am
DSM
-
PDX
28h 48m
1 stop
$364Multiple Airlines
Thu, Feb 5 - Sun, Feb 8
American Airlines Logo
8:00 am - 11:29 pm
PDX
-
DSM
13h 29m
1 stop
American Airlines Logo
2:39 pm - 11:33 pm
DSM
-
PDX
10h 54m
1 stop
$366American Airlines
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
11:35 pm - 9:01 am
PDX
-
DSM
7h 26m
1 stop
American Airlines Logo
3:26 pm - 11:27 pm
DSM
-
PDX
10h 01m
1 stop
$367American Airlines
Thu, Feb 19 - Tue, Feb 24
American Airlines Logo
11:35 pm - 1:05 pm
PDX
-
DSM
11h 30m
1 stop
American Airlines Logo
1:38 pm - 12:17 am
DSM
-
PDX
12h 39m
1 stop
$368American Airlines
Tue, Feb 17 - Fri, Feb 20
American Airlines Logo
11:59 pm - 1:48 pm
PDX
-
DSM
11h 49m
1 stop
American Airlines Logo
11:58 am - 10:32 pm
DSM
-
PDX
12h 34m
1 stop
$373American Airlines
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
11:35 pm - 9:01 am
PDX
-
DSM
7h 26m
1 stop
American Airlines Logo
1:38 pm - 12:17 am
DSM
-
PDX
12h 39m
1 stop
$375American Airlines
Sat, Feb 21 - Fri, Feb 27
American Airlines Logo
1:52 pm - 11:48 pm
PDX
-
DSM
7h 56m
1 stop
American Airlines Logo
7:44 pm - 10:58 am
DSM
-
PDX
17h 14m
1 stop
$385American Airlines
Thu, Feb 12 - Sun, Feb 15
American Airlines Logo
11:52 am - 11:40 pm
PDX
-
DSM
9h 48m
1 stop
American Airlines Logo
7:44 pm - 10:58 am
DSM
-
PDX
17h 14m
1 stop
$393American Airlines
Fri, Feb 20 - Sun, Feb 22
Southwest Logo
7:00 am - 5:55 pm
PDX
-
DSM
8h 55m
2 stops
Southwest Logo
6:50 am - 10:15 am
DSM
-
PDX
5h 25m
1 stop
$394Southwest
Tue, May 5 - Fri, May 8

American Airlines flights from Portland to Des Moines

Our best American Airlines deals on Portland to Des Moines flight tickets
American Airlines
Feb 17
PDX11:35 pmPortland
11h 30m
1 stop
DSM1:05 pmDes Moines
Feb 24
DSM1:38 pmDes Moines
12h 39m
1 stop
PDX12:17 amPortland
$343
American Airlines
Apr 14
PDX8:00 amPortland
13h 29m
1 stop
DSM11:29 pmDes Moines
Apr 18
DSM2:39 pmDes Moines
10h 54m
1 stop
PDX11:33 pmPortland
$366
American Airlines
Feb 19
PDX11:35 pmPortland
7h 26m
1 stop
DSM9:01 amDes Moines
Feb 24
DSM3:26 pmDes Moines
10h 01m
1 stop
PDX11:27 pmPortland
$367

United Airlines flights from Portland to Des Moines

Our best United Airlines deals on Portland to Des Moines flight tickets
United Airlines
Feb 17
PDX4:00 pmPortland
5h 43m
1 stop
DSM11:43 pmDes Moines
Feb 24
DSM9:04 amDes Moines
11h 51m
2 stops
PDX6:55 pmPortland
$356
United Airlines
Feb 17
PDX5:05 amPortland
5h 45m
1 stop
DSM12:50 pmDes Moines
Feb 20
DSM3:24 pmDes Moines
9h 50m
2 stops
PDX11:14 pmPortland
$426
United Airlines
Feb 12
PDX12:57 pmPortland
7h 23m
1 stop
DSM10:20 pmDes Moines
Feb 15
DSM5:30 amDes Moines
9h 08m
2 stops
PDX12:38 pmPortland
$427

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 2/25

6:00 am-3:40 pm

1 stop7h 40m

Des Moines

Sat 2/28

6:50 am-12:44 pm

1 stop7h 54m

$357

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 2/5

11:28 am-3:40 pm

1 stop26h 12m

Des Moines

Sun 2/8

8:30 am-11:18 am

1 stop28h 48m

$364

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Tue 4/14

8:00 am-11:29 pm

1 stop13h 29m

Des Moines

Sat 4/18

2:39 pm-11:33 pm

1 stop10h 54m

$366

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 2/19

11:35 pm-9:01 am

1 stop7h 26m

Des Moines

Tue 2/24

3:26 pm-11:27 pm

1 stop10h 01m

$367

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Tue 2/17

11:35 pm-1:05 pm

1 stop11h 30m

Des Moines

Fri 2/20

1:38 pm-12:17 am

1 stop12h 39m

$368

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Tue 4/14

11:59 pm-1:48 pm

1 stop11h 49m

Des Moines

Sat 4/18

11:58 am-10:32 pm

1 stop12h 34m

$373

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Sat 2/21

11:35 pm-9:01 am

1 stop7h 26m

Des Moines

Fri 2/27

1:38 pm-12:17 am

1 stop12h 39m

$375

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 2/12

1:52 pm-11:48 pm

1 stop7h 56m

Des Moines

Sun 2/15

7:44 pm-10:58 am

1 stop17h 14m

$385

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Fri 2/20

11:52 am-11:40 pm

1 stop9h 48m

Des Moines

Sun 2/22

7:44 pm-10:58 am

1 stop17h 14m

$393

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Tue 5/5

7:00 am-5:55 pm

2 stops8h 55m

Des Moines

Fri 5/8

6:50 am-10:15 am

1 stop5h 25m

$394

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Portland to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then August is your next best option. Flight prices from Portland to Des Moines during August average around $254.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Portland to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $190. Flights from Portland to Des Moines on a Sunday will generally be more expensive and average around $212. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Portland to Des Moines in the morning for as low as $142. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $215. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Portland to Des Moines flight route?

Fly from Portland to Des Moines for the best Portland - Des Moines flight prices

How far in advance should I book a flight to Des Moines?

You are more likely to see cheaper flights to Des Moines from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $342 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Portland for as low as $210 on momondo.

What cabin class options are available on Portland to Des Moines flights?

There is only 1 cabin class available to choose from on Portland to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Portland to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Portland to Des Moines.

How have Portland to Des Moines flight prices changed over time?

As of January 2026, prices for Portland to Des Moines flights are approximately 35% cheaper when compared to flights at the same time last year.

When to book flights from Portland to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Des Moines (PDX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Des Moines

Fastest flight time

5h 12m

Direct flights

Fri

Airports in Des Moines

1 airport
The fastest flight from Portland to Des Moines takes 5h 12m
Direct flights go from Portland to Des Moines on Friday. There are no airlines offering direct flights.
There is 1 airport in Des Moines. From Portland there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is Portland to Des Moines by plane?

    There are 1470.3 mi between Portland and Des Moines. 5h 12m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

    Prices for flights from Portland Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

  • How old do you have to be to fly from Portland Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Portland to Des Moines?

  • What is the most popular airline from Portland to Des Moines?

Best airlines flying from Portland to Des Moines

Compare and see reviews for airlines that fly from Portland to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $81Free CancellationRating
7.2
705 reviews
Search Allegiant Air flights
FrontierPriceFrom $140Free CancellationRating
5.7
3,056 reviews
Search Frontier flights
DeltaPriceFrom $143Free CancellationRating
7.9
8,085 reviews
Search Delta flights
United AirlinesPriceFrom $252Free CancellationRating
7.4
9,189 reviews
Search United Airlines flights
American AirlinesPriceFrom $261Free CancellationRating
7.2
11,169 reviews
Search American Airlines flights
SouthwestPriceFrom $364Free CancellationRating
8.0
4,266 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Des Moines.

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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