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Cheap flights from Portland to Des Moines from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Des Moines departing on 12/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Portland to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:40 am - 10:17 amPDX-DSM
7h 37m1 stop
Delta Logo
10:57 am - 5:35 pmDSM-PDX
8h 38m1 stop
$261Delta
Find Deal
mié., feb. 18 - sáb., feb. 21
United Airlines Logo
1:40 pm - 11:43 pmPDX-DSM
8h 03m2 stops
United Airlines Logo
3:24 pm - 10:56 pmDSM-PDX
9h 32m1 stop
$306United Airlines
Find Deal
jue., feb. 19 - sáb., feb. 21
Delta Logo
6:00 am - 3:41 pmPDX-DSM
7h 41m1 stop
Delta Logo
6:54 am - 12:46 pmDSM-PDX
7h 52m1 stop
$319Delta
Find Deal
jue., ene. 15 - dom., ene. 18
Multiple Airlines Logo
9:08 pm - 10:34 pmPDX-DSM
23h 26m1 stop
Multiple Airlines Logo
4:02 pm - 7:06 pmDSM-PDX
29h 04m1 stop
$322Multiple Airlines
Find Deal
jue., mar. 12 - sáb., mar. 21
Delta Logo
12:40 am - 10:17 amPDX-DSM
7h 37m1 stop
Delta Logo
4:21 pm - 8:32 pmDSM-PDX
6h 11m1 stop
$344Delta
Find Deal
jue., feb. 19 - dom., feb. 22
Multiple Airlines Logo
12:51 pm - 7:03 pmPDX-DSM
28h 12m1 stop
Multiple Airlines Logo
8:30 am - 8:36 amDSM-PDX
26h 06m1 stop
$346Multiple Airlines
Find Deal
jue., dic. 4 - dom., dic. 7
Delta Logo
12:32 am - 10:21 amPDX-DSM
7h 49m1 stop
Delta Logo
2:16 pm - 10:19 pmDSM-PDX
10h 03m1 stop
$351Delta
Find Deal
lun., dic. 8 - mar., dic. 16
Southwest Logo
7:15 am - 7:55 pmPDX-DSM
10h 40m2 stops
Southwest Logo
12:05 pm - 5:50 pmDSM-PDX
7h 45m1 stop
$356Southwest
Find Deal
mar., dic. 9 - mar., dic. 16
Delta Logo
12:32 am - 10:21 amPDX-DSM
7h 49m1 stop
Delta Logo
2:59 pm - 8:52 pmDSM-PDX
7h 53m1 stop
$357Delta
Find Deal
lun., dic. 1 - mié., dic. 3
Southwest Logo
9:55 am - 7:55 pmPDX-DSM
8h 00m2 stops
Southwest Logo
12:05 pm - 9:25 pmDSM-PDX
11h 20m2 stops
$361Southwest
Find Deal
mar., dic. 9 - mar., dic. 16

Delta flights from Portland to Des Moines

Our best Delta deals on Portland to Des Moines flight tickets
Delta
Feb 18
PDX12:40 amPortland
7h 37m
1 stop
DSM10:17 amDes Moines
Feb 21
DSM10:57 amDes Moines
8h 38m
1 stop
PDX5:35 pmPortland
$261
Find similar
Delta
Nov 27
PDX11:53 amPortland
8h 40m
1 stop
DSM10:33 pmDes Moines
Dec 3
DSM2:59 pmDes Moines
7h 53m
1 stop
PDX8:52 pmPortland
$309
Find similar
Delta
Jan 15
PDX6:00 amPortland
7h 41m
1 stop
DSM3:41 pmDes Moines
Jan 18
DSM6:54 amDes Moines
7h 52m
1 stop
PDX12:46 pmPortland
$319
Find similar

Southwest flights from Portland to Des Moines

Our best Southwest deals on Portland to Des Moines flight tickets
Southwest
Dec 9
PDX7:15 amPortland
10h 40m
2 stops
DSM7:55 pmDes Moines
Dec 16
DSM12:05 pmDes Moines
7h 45m
1 stop
PDX5:50 pmPortland
$356
Find similar
Southwest
Dec 9
PDX9:55 amPortland
8h 00m
2 stops
DSM7:55 pmDes Moines
Dec 16
DSM12:05 pmDes Moines
11h 20m
2 stops
PDX9:25 pmPortland
$361
Find similar
Southwest
Feb 19
PDX9:25 amPortland
9h 55m
2 stops
DSM9:20 pmDes Moines
Feb 22
DSM6:15 pmDes Moines
8h 30m
2 stops
PDX12:45 amPortland
$394
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 19, 2025.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

mié. 2/18

12:40 am-10:17 am

1 stop7h 37m

Des Moines

sáb. 2/21

10:57 am-5:35 pm

1 stop8h 38m

$261

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

jue. 2/19

1:40 pm-11:43 pm

2 stops8h 03m

Des Moines

sáb. 2/21

3:24 pm-10:56 pm

1 stop9h 32m

$306

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

jue. 1/15

6:00 am-3:41 pm

1 stop7h 41m

Des Moines

dom. 1/18

6:54 am-12:46 pm

1 stop7h 52m

$319

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

jue. 3/12

9:08 pm-10:34 pm

1 stop23h 26m

Des Moines

sáb. 3/21

4:02 pm-7:06 pm

1 stop29h 04m

$322

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

jue. 2/19

12:40 am-10:17 am

1 stop7h 37m

Des Moines

dom. 2/22

4:21 pm-8:32 pm

1 stop6h 11m

$344

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

jue. 12/4

12:51 pm-7:03 pm

1 stop28h 12m

Des Moines

dom. 12/7

8:30 am-8:36 am

1 stop26h 06m

$346

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

lun. 12/8

12:32 am-10:21 am

1 stop7h 49m

Des Moines

mar. 12/16

2:16 pm-10:19 pm

1 stop10h 03m

$351

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

mar. 12/9

7:15 am-7:55 pm

2 stops10h 40m

Des Moines

mar. 12/16

12:05 pm-5:50 pm

1 stop7h 45m

$356

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

lun. 12/1

12:32 am-10:21 am

1 stop7h 49m

Des Moines

mié. 12/3

2:59 pm-8:52 pm

1 stop7h 53m

$357

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

mar. 12/9

9:55 am-7:55 pm

2 stops8h 00m

Des Moines

mar. 12/16

12:05 pm-9:25 pm

2 stops11h 20m

$361

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Portland to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then August is your next best option. Flight prices from Portland to Des Moines during August average around $254.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Portland to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $190. Flights from Portland to Des Moines on a Sunday will generally be more expensive and average around $212. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Portland to Des Moines in the morning for as low as $142. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $371. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Portland to Des Moines flight route?

Fly from Portland to Des Moines for the best Portland - Des Moines flight prices

How far in advance should I book a flight to Des Moines?

You are more likely to see cheaper flights to Des Moines from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $339 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Portland for as low as $210 on momondo.

What cabin class options are available on Portland to Des Moines flights?

There is only 1 cabin class available to choose from on Portland to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Portland to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Portland to Des Moines.

How have Portland to Des Moines flight prices changed over time?

As of November 2025, prices for Portland to Des Moines flights are approximately 26% cheaper when compared to flights at the same time last year.

When to book flights from Portland to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Des Moines (PDX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Des Moines

Direct flights

None
There are no direct flights from Portland to Des Moines. There are no popular flight routes from Portland to Des Moines.
Search flight deals

  • How far is Portland to Des Moines by plane?

    There are 1470.3 mi between Portland and Des Moines. 5h 42m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

    Prices for flights from Portland Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

  • How old do you have to be to fly from Portland Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Portland to Des Moines?

  • What is the most popular airline from Portland to Des Moines?

Best airlines flying from Portland to Des Moines

Compare and see reviews for airlines that fly from Portland to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $114Free CancellationRating
7.2
700 reviews
Search Allegiant Air flights
FrontierPriceFrom $150Free CancellationRating
5.8
3,105 reviews
Search Frontier flights
DeltaPriceFrom $238Free CancellationRating
7.9
8,002 reviews
Search Delta flights
American AirlinesPriceFrom $261Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
United AirlinesPriceFrom $269Free CancellationRating
7.4
9,019 reviews
Search United Airlines flights
SouthwestPriceFrom $364Free CancellationRating
8.0
4,248 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Newton
Pella
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Des Moines.

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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