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Cheap flights from Portland to Des Moines from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Des Moines departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Portland to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:46 am - 10:26 pm
PDX
-
DSM
8h 40m1 stop
American Airlines Logo
3:26 pm - 9:45 pm
DSM
-
PDX
8h 19m1 stop
$320American Airlines
Wed, Feb 18 - Sat, Feb 21
Multiple Airlines Logo
12:05 pm - 3:40 pm
PDX
-
DSM
25h 35m2 stops
Multiple Airlines Logo
8:30 am - 10:33 am
DSM
-
PDX
28h 03m1 stop
$341Multiple Airlines
Thu, Jan 8 - Thu, Jan 15
United Airlines Logo
3:45 pm - 11:44 pm
PDX
-
DSM
5h 59m1 stop
United Airlines Logo
9:03 am - 1:45 pm
DSM
-
PDX
6h 42m1 stop
$351United Airlines
Wed, Jan 21 - Wed, Jan 28
Southwest Logo
5:05 am - 2:40 pm
PDX
-
DSM
7h 35m1 stop
Southwest Logo
12:05 pm - 9:20 pm
DSM
-
PDX
11h 15m2 stops
$356Southwest
Wed, Jan 21 - Wed, Jan 28
Southwest Logo
6:45 am - 7:20 pm
PDX
-
DSM
10h 35m2 stops
Southwest Logo
12:05 pm - 7:55 pm
DSM
-
PDX
9h 50m2 stops
$361Southwest
Wed, Jan 21 - Wed, Jan 28
Delta Logo
6:00 am - 3:40 pm
PDX
-
DSM
7h 40m1 stop
Delta Logo
10:57 am - 5:33 pm
DSM
-
PDX
8h 36m1 stop
$364Delta
Thu, Feb 19 - Tue, Feb 24
American Airlines Logo
11:59 pm - 10:47 am
PDX
-
DSM
8h 48m1 stop
American Airlines Logo
6:20 pm - 12:16 am
DSM
-
PDX
7h 56m1 stop
$377American Airlines
Thu, Feb 19 - Mon, Feb 23
Multiple Airlines Logo
5:41 pm - 3:40 pm
PDX
-
DSM
19h 59m1 stop
Multiple Airlines Logo
8:30 am - 10:33 am
DSM
-
PDX
28h 03m1 stop
$383Multiple Airlines
Thu, Jan 8 - Thu, Jan 15
Multiple Airlines Logo
12:05 pm - 3:40 pm
PDX
-
DSM
25h 35m2 stops
Multiple Airlines Logo
7:00 am - 8:47 pm
DSM
-
PDX
15h 47m2 stops
$388Multiple Airlines
Thu, Jan 8 - Thu, Jan 15
United Airlines Logo
8:30 am - 9:41 pm
PDX
-
DSM
11h 11m2 stops
United Airlines Logo
5:03 pm - 9:15 pm
DSM
-
PDX
6h 12m1 stop
$394United Airlines
Wed, Feb 18 - Sat, Feb 21

American Airlines flights from Portland to Des Moines

Our best American Airlines deals on Portland to Des Moines flight tickets
American Airlines
Feb 18
PDX11:46 amPortland
8h 40m
1 stop
DSM10:26 pmDes Moines
Feb 21
DSM3:26 pmDes Moines
8h 19m
1 stop
PDX9:45 pmPortland
$320
Find similar
American Airlines
Feb 19
PDX11:59 pmPortland
8h 48m
1 stop
DSM10:47 amDes Moines
Feb 23
DSM6:20 pmDes Moines
7h 56m
1 stop
PDX12:16 amPortland
$377
Find similar
American Airlines
Apr 14
PDX6:30 amPortland
14h 56m
1 stop
DSM11:26 pmDes Moines
Apr 18
DSM2:38 pmDes Moines
10h 59m
1 stop
PDX11:37 pmPortland
$395
Find similar

United Airlines flights from Portland to Des Moines

Our best United Airlines deals on Portland to Des Moines flight tickets
United Airlines
Jan 21
PDX3:45 pmPortland
5h 59m
1 stop
DSM11:44 pmDes Moines
Jan 28
DSM9:03 amDes Moines
6h 42m
1 stop
PDX1:45 pmPortland
$351
Find similar
United Airlines
Feb 18
PDX8:30 amPortland
11h 11m
2 stops
DSM9:41 pmDes Moines
Feb 21
DSM5:03 pmDes Moines
6h 12m
1 stop
PDX9:15 pmPortland
$394
Find similar
United Airlines
Feb 14
PDX8:30 amPortland
11h 11m
2 stops
DSM9:41 pmDes Moines
Feb 18
DSM8:00 amDes Moines
16h 59m
3 stops
PDX10:59 pmPortland
$396
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 24, 2025.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 2/18

11:46 am-10:26 pm

1 stop8h 40m

Des Moines

Sat 2/21

3:26 pm-9:45 pm

1 stop8h 19m

$320

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 1/8

12:05 pm-3:40 pm

2 stops25h 35m

Des Moines

Thu 1/15

8:30 am-10:33 am

1 stop28h 03m

$341

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 1/21

3:45 pm-11:44 pm

1 stop5h 59m

Des Moines

Wed 1/28

9:03 am-1:45 pm

1 stop6h 42m

$351

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 1/21

5:05 am-2:40 pm

1 stop7h 35m

Des Moines

Wed 1/28

12:05 pm-9:20 pm

2 stops11h 15m

$356

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 1/21

6:45 am-7:20 pm

2 stops10h 35m

Des Moines

Wed 1/28

12:05 pm-7:55 pm

2 stops9h 50m

$361

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 2/19

6:00 am-3:40 pm

1 stop7h 40m

Des Moines

Tue 2/24

10:57 am-5:33 pm

1 stop8h 36m

$364

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 2/19

11:59 pm-10:47 am

1 stop8h 48m

Des Moines

Mon 2/23

6:20 pm-12:16 am

1 stop7h 56m

$377

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 1/8

5:41 pm-3:40 pm

1 stop19h 59m

Des Moines

Thu 1/15

8:30 am-10:33 am

1 stop28h 03m

$383

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Thu 1/8

12:05 pm-3:40 pm

2 stops25h 35m

Des Moines

Thu 1/15

7:00 am-8:47 pm

2 stops15h 47m

$388

PortlandDes Moines

PDX - DSM

PDXDSM

Portland

Wed 2/18

8:30 am-9:41 pm

2 stops11h 11m

Des Moines

Sat 2/21

5:03 pm-9:15 pm

1 stop6h 12m

$394

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Portland to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then August is your next best option. Flight prices from Portland to Des Moines during August average around $254.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Portland to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $192. Flights from Portland to Des Moines on a Sunday will generally be more expensive and average around $212. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Portland to Des Moines in the morning for as low as $142. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $371. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Portland to Des Moines flight route?

Fly from Portland to Des Moines for the best Portland - Des Moines flight prices

How far in advance should I book a flight to Des Moines?

You are more likely to see cheaper flights to Des Moines from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $338 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Portland for as low as $210 on momondo.

What cabin class options are available on Portland to Des Moines flights?

There is only 1 cabin class available to choose from on Portland to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Portland to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Portland to Des Moines.

How have Portland to Des Moines flight prices changed over time?

As of December 2025, prices for Portland to Des Moines flights are approximately 63% more expensive when compared to flights at the same time last year.

When to book flights from Portland to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Des Moines (PDX to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Des Moines

Fastest flight time

3h 14m

Direct flights

Fri

Airports in Des Moines

1 airport
The fastest flight from Portland to Des Moines takes 3h 14m
Direct flights go from Portland to Des Moines on Friday. There are no airlines offering direct flights.
There is 1 airport in Des Moines. From Portland there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is Portland to Des Moines by plane?

    There are 1470.3 mi between Portland and Des Moines. 3h 14m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

    Prices for flights from Portland Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

  • How old do you have to be to fly from Portland Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Portland to Des Moines?

  • What is the most popular airline from Portland to Des Moines?

Best airlines flying from Portland to Des Moines

Compare and see reviews for airlines that fly from Portland to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $114Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
FrontierPriceFrom $150Free CancellationRating
5.8
3,073 reviews
Search Frontier flights
DeltaPriceFrom $238Free CancellationRating
7.9
8,015 reviews
Search Delta flights
United AirlinesPriceFrom $252Free CancellationRating
7.4
9,111 reviews
Search United Airlines flights
American AirlinesPriceFrom $261Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights
SouthwestPriceFrom $364Free CancellationRating
8.0
4,256 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Des Moines.

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

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