Cheap flights from Pittsburgh to South Carolina from $46

The cheapest month to fly to South Carolina from Pittsburgh is in August. Flight prices, which tend to average around $158, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Pittsburgh during July instead. Flights to South Carolina in July, while not as cheap as those in August, still average around $201.

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $153. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $232.

Our data shows that the cheapest Pittsburgh to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $153. Try not to purchase tickets in the afternoon because they tend to be around $238. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Pittsburgh to Myrtle Beach Intl for the best Pittsburgh - South Carolina flight prices

You are more likely to see cheaper flights to South Carolina from Pittsburgh when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $252 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Pittsburgh for as low as $146 on momondo.

There are 2 cabin classes available to choose from on Pittsburgh to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Breeze Airways, Spirit Airlines, and Delta are the most popular carriers operating from Pittsburgh to South Carolina

Allegiant Air, American Airlines and Spirit Airlines are the top three most popular airlines that fly to South Carolina from Pittsburgh according to our data. Allegiant Air is the first choice among our users, with 29% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

The number of flights available between Pittsburgh and South Carolina is 4 per day as of March 2026. The most frequent departure time is 3:00PM, with 100% of daily flights leaving in the afternoon.

As of March 2026, there are 32 flights per week flying from Pittsburgh to South Carolina. The most common day of the week flights depart is Wed, with 28% of flights taking off on this day.