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Cheap flights from Myrtle Beach to Buffalo from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Buffalo departing on 9/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Myrtle Beach to Buffalo

Cheap round-trip flights

Delta Logo
4:45 pm - 10:57 pmMYR-BUF
6h 12m1 stop
Delta Logo
5:20 am - 9:34 amBUF-MYR
4h 14m1 stop
$238Delta
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Fri, Oct 31 - Sun, Nov 2
Delta Logo
4:00 pm - 10:52 pmMYR-BUF
6h 52m2 stops
Delta Logo
5:16 am - 11:01 amBUF-MYR
5h 45m1 stop
$243Delta
Find Deal
Fri, Oct 31 - Sun, Nov 2
American Airlines Logo
8:07 pm - 12:08 amMYR-BUF
4h 01m1 stop
American Airlines Logo
6:00 am - 12:13 pmBUF-MYR
6h 13m2 stops
$248American Airlines
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Sat, Nov 8 - Mon, Nov 10
American Airlines Logo
2:45 pm - 10:52 pmMYR-BUF
8h 07m2 stops
American Airlines Logo
6:00 am - 12:13 pmBUF-MYR
6h 13m2 stops
$253American Airlines
Find Deal
Sat, Nov 8 - Mon, Nov 10
Delta Logo
6:55 pm - 11:37 pmMYR-BUF
4h 42m1 stop
Delta Logo
7:08 pm - 11:49 pmBUF-MYR
4h 41m1 stop
$259Delta
Find Deal
Fri, Oct 3 - Sun, Oct 5
American Airlines Logo
11:20 am - 5:55 pmMYR-BUF
6h 35m2 stops
American Airlines Logo
11:50 am - 5:20 pmBUF-MYR
5h 30m1 stop
$264American Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 5
Southwest Logo
8:05 pm - 11:50 pmMYR-BUF
3h 45m1 stop
Southwest Logo
1:05 pm - 11:30 pmBUF-MYR
10h 25m2 stops
$317Southwest
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Fri, Oct 10 - Sun, Oct 12
Southwest Logo
6:10 pm - 11:45 pmMYR-BUF
5h 35m1 stop
Southwest Logo
5:30 am - 9:45 amBUF-MYR
4h 15m1 stop
$348Southwest
Find Deal
Sat, Nov 22 - Mon, Dec 1
United Airlines Logo
5:12 pm - 11:38 pmMYR-BUF
6h 26m1 stop
United Airlines Logo
7:05 am - 2:42 pmBUF-MYR
7h 37m1 stop
$437United Airlines
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Fri, Aug 15 - Tue, Aug 19
United Airlines Logo
4:45 pm - 9:54 amMYR-BUF
17h 09m1 stop
United Airlines Logo
7:05 am - 2:42 pmBUF-MYR
7h 37m1 stop
$463United Airlines
Find Deal
Thu, Aug 28 - Sun, Aug 31

Delta flights from Myrtle Beach to Buffalo

Our best Delta deals on Myrtle Beach to Buffalo flight tickets
Delta
Oct 31
MYR4:45 pmMyrtle Beach Intl
6h 12m
1 stop
BUF10:57 pmBuffalo
Nov 2
BUF5:20 amBuffalo
4h 14m
1 stop
MYR9:34 amMyrtle Beach Intl
$238
Find similar
Delta
Oct 31
MYR4:00 pmMyrtle Beach Intl
6h 52m
2 stops
BUF10:52 pmBuffalo
Nov 2
BUF5:16 amBuffalo
5h 45m
1 stop
MYR11:01 amMyrtle Beach Intl
$243
Find similar
Delta
Oct 3
MYR6:55 pmMyrtle Beach Intl
4h 42m
1 stop
BUF11:37 pmBuffalo
Oct 5
BUF7:08 pmBuffalo
4h 41m
1 stop
MYR11:49 pmMyrtle Beach Intl
$259
Find similar

Southwest flights from Myrtle Beach to Buffalo

Our best Southwest deals on Myrtle Beach to Buffalo flight tickets
Southwest
Oct 10
MYR8:05 pmMyrtle Beach Intl
3h 45m
1 stop
BUF11:50 pmBuffalo
Oct 12
BUF1:05 pmBuffalo
10h 25m
2 stops
MYR11:30 pmMyrtle Beach Intl
$317
Find similar
Southwest
Nov 22
MYR6:10 pmMyrtle Beach Intl
5h 35m
1 stop
BUF11:45 pmBuffalo
Dec 1
BUF5:30 amBuffalo
4h 15m
1 stop
MYR9:45 amMyrtle Beach Intl
$348
Find similar
Southwest
Aug 29
MYR7:00 amMyrtle Beach Intl
9h 30m
2 stops
BUF4:30 pmBuffalo
Sep 5
BUF10:30 amBuffalo
9h 20m
2 stops
MYR7:50 pmMyrtle Beach Intl
$354
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Fri 10/31

4:45 pm-10:57 pm

1 stop6h 12m

Buffalo

Sun 11/2

5:20 am-9:34 am

1 stop4h 14m

$238

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Fri 10/31

4:00 pm-10:52 pm

2 stops6h 52m

Buffalo

Sun 11/2

5:16 am-11:01 am

1 stop5h 45m

$243

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Sat 11/8

8:07 pm-12:08 am

1 stop4h 01m

Buffalo

Mon 11/10

6:00 am-12:13 pm

2 stops6h 13m

$248

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Sat 11/8

2:45 pm-10:52 pm

2 stops8h 07m

Buffalo

Mon 11/10

6:00 am-12:13 pm

2 stops6h 13m

$253

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Fri 10/3

6:55 pm-11:37 pm

1 stop4h 42m

Buffalo

Sun 10/5

7:08 pm-11:49 pm

1 stop4h 41m

$259

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Fri 10/3

11:20 am-5:55 pm

2 stops6h 35m

Buffalo

Sun 10/5

11:50 am-5:20 pm

1 stop5h 30m

$264

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Fri 10/10

8:05 pm-11:50 pm

1 stop3h 45m

Buffalo

Sun 10/12

1:05 pm-11:30 pm

2 stops10h 25m

$317

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Sat 11/22

6:10 pm-11:45 pm

1 stop5h 35m

Buffalo

Mon 12/1

5:30 am-9:45 am

1 stop4h 15m

$348

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Fri 8/15

5:12 pm-11:38 pm

1 stop6h 26m

Buffalo

Tue 8/19

7:05 am-2:42 pm

1 stop7h 37m

$437

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

Thu 8/28

4:45 pm-9:54 am

1 stop17h 09m

Buffalo

Sun 8/31

7:05 am-2:42 pm

1 stop7h 37m

$463

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Myrtle Beach to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Buffalo?

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of September, then book flights to Buffalo from Myrtle Beach during August instead. Flights to Buffalo in August, while not as cheap as those in September, still average around $321.

What is the cheapest day to depart on your flight to Buffalo?

Our data shows that Tuesday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $316. Flights from Myrtle Beach to Buffalo on a Monday will generally be more expensive and average around $393. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Buffalo?

In the afternoon is the cheapest time of day to fly from Myrtle Beach to Buffalo when you can find flight prices for as low as $336. Flying to Buffalo in the afternoon is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Buffalo, so prices are often more expensive at around $376 per ticket.

How have Myrtle Beach to Buffalo flight prices changed over time?

As of July 2025, prices for Myrtle Beach to Buffalo flights are approximately 20% cheaper when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Buffalo (MYR to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Buffalo

Best Price Found

$119

Fastest flight time

3h 35m

Direct flights

None

Airports in Buffalo

1 airport
The best one-way flight to Buffalo from Myrtle Beach in the past 72 hours is $119. The best round-trip flight deal from Myrtle Beach to Buffalo found on momondo in the last 72 hours is $238.
The fastest flight from Myrtle Beach to Buffalo takes 3h 35m
There are no direct flights from Myrtle Beach to Buffalo. Popular non-direct route for this connection is Myrtle Beach Intl Airport - Buffalo Airport.
There is 1 airport near Buffalo: Buffalo (BUF)
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  • How far is Myrtle Beach Intl to Buffalo by plane?

    The distance between Myrtle Beach Intl and Buffalo is about 635.0 mi. Typically, this will take 3h 35m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Buffalo Airport?

    Prices for flights from Myrtle Beach Intl Airport to Buffalo Airport were last updated today.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Buffalo Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Buffalo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Myrtle Beach Intl Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Buffalo?

Best airlines flying from Myrtle Beach to Buffalo

Compare and see reviews for airlines that fly from Myrtle Beach to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $236Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $276Free CancellationRating
8.0
4,246 reviews
Search Southwest flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Williamsville
Amherst
Tonawanda
Cheektowaga
Grand Island
Lockport
Orchard Park
West Seneca
East Aurora
Bowmansville
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Buffalo?

It is quick and easy to find Myrtle Beach to Buffalo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Buffalo that suits you.

Can I find flights from Myrtle Beach to Buffalo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Myrtle Beach to Buffalo flights to just show those with flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Myrtle Beach to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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