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Cheap flights from Missouri to Florence from $441

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Florence departing on 8/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

American Airlines Logo
6:16 am - 11:46 amMCI-FLO
4h 30m1 stop
American Airlines Logo
6:20 am - 10:12 amFLO-MCI
4h 52m1 stop
$441American Airlines
Find Deal
Wed, Aug 20 - Wed, Aug 27
American Airlines Logo
6:33 pm - 11:50 pmMCI-FLO
4h 17m1 stop
American Airlines Logo
12:27 pm - 4:24 pmFLO-MCI
4h 57m1 stop
$442American Airlines
Find Deal
Mon, Sep 1 - Mon, Sep 8
American Airlines Logo
3:12 pm - 11:02 pmMCI-FLO
6h 50m1 stop
American Airlines Logo
6:20 am - 2:01 pmFLO-MCI
8h 41m2 stops
$446American Airlines
Find Deal
Wed, Aug 20 - Wed, Aug 27
American Airlines Logo
6:33 pm - 11:50 pmMCI-FLO
4h 17m1 stop
American Airlines Logo
12:27 pm - 7:05 pmFLO-MCI
7h 38m2 stops
$447American Airlines
Find Deal
Mon, Sep 1 - Mon, Sep 8
American Airlines Logo
10:19 am - 11:02 pmMCI-FLO
11h 43m2 stops
American Airlines Logo
3:30 pm - 9:45 pmFLO-MCI
7h 15m2 stops
$451American Airlines
Find Deal
Wed, Aug 20 - Wed, Aug 27
American Airlines Logo
5:17 am - 2:09 pmMCI-FLO
7h 52m2 stops
American Airlines Logo
12:27 pm - 9:48 pmFLO-MCI
10h 21m2 stops
$452American Airlines
Find Deal
Mon, Sep 1 - Mon, Sep 8
American Airlines Logo
5:21 pm - 10:18 amMCI-FLO
15h 57m2 stops
American Airlines Logo
11:14 am - 10:31 pmFLO-MCI
12h 17m2 stops
$458American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
6:33 pm - 11:40 pmMCI-FLO
4h 07m1 stop
American Airlines Logo
2:29 pm - 5:45 pmFLO-MCI
4h 16m1 stop
$491American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
2:05 pm - 11:40 pmMCI-FLO
8h 35m2 stops
American Airlines Logo
11:14 am - 5:45 pmFLO-MCI
7h 31m1 stop
$496American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13

American Airlines flights from Missouri to Florence, South Carolina

Our best American Airlines deals on Missouri to Florence, South Carolina flight tickets
American Airlines
Aug 20
MCI6:16 amKansas City
4h 30m
1 stop
FLO11:46 amFlorence
Aug 27
FLO6:20 amFlorence
4h 52m
1 stop
MCI10:12 amKansas City
$441
Find similar
American Airlines
Sep 1
MCI6:33 pmKansas City
4h 17m
1 stop
FLO11:50 pmFlorence
Sep 8
FLO12:27 pmFlorence
4h 57m
1 stop
MCI4:24 pmKansas City
$442
Find similar
American Airlines
Aug 20
MCI3:12 pmKansas City
6h 50m
1 stop
FLO11:02 pmFlorence
Aug 27
FLO6:20 amFlorence
8h 41m
2 stops
MCI2:01 pmKansas City
$446
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Missouri to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Wed 8/20

6:16 am-11:46 am

1 stop4h 30m

Florence

Wed 8/27

6:20 am-10:12 am

1 stop4h 52m

$441

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Mon 9/1

6:33 pm-11:50 pm

1 stop4h 17m

Florence

Mon 9/8

12:27 pm-4:24 pm

1 stop4h 57m

$442

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Wed 8/20

3:12 pm-11:02 pm

1 stop6h 50m

Florence

Wed 8/27

6:20 am-2:01 pm

2 stops8h 41m

$446

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Mon 9/1

6:33 pm-11:50 pm

1 stop4h 17m

Florence

Mon 9/8

12:27 pm-7:05 pm

2 stops7h 38m

$447

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Wed 8/20

10:19 am-11:02 pm

2 stops11h 43m

Florence

Wed 8/27

3:30 pm-9:45 pm

2 stops7h 15m

$451

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Mon 9/1

5:17 am-2:09 pm

2 stops7h 52m

Florence

Mon 9/8

12:27 pm-9:48 pm

2 stops10h 21m

$452

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Wed 12/10

5:21 pm-10:18 am

2 stops15h 57m

Florence

Sat 12/13

11:14 am-10:31 pm

2 stops12h 17m

$458

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Wed 12/10

6:33 pm-11:40 pm

1 stop4h 07m

Florence

Sat 12/13

2:29 pm-5:45 pm

1 stop4h 16m

$491

Kansas CityFlorence

MCI - FLO

MCIFLO

Kansas City

Wed 12/10

2:05 pm-11:40 pm

2 stops8h 35m

Florence

Sat 12/13

11:14 am-5:45 pm

1 stop7h 31m

$496

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Missouri to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Missouri according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Missouri to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Florence, South Carolina

Best Price Found

$441

Fastest flight time

4h 07m

Direct flights

None

Airports in Florence, South Carolina

1 airport
The best flight deal from Missouri to Florence, South Carolina found on momondo in the last 72 hours is $441
The fastest flight from Missouri to Florence, South Carolina takes 4h 07m
There are no direct flights from Missouri to Florence, South Carolina. Popular non-direct route for this connection is Kansas City Airport - Florence Airport.
There is 1 airport near Florence, South Carolina: Florence (FLO)
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  • When did momondo last update prices for flights from Missouri to Florence Airport?

    Prices for flights from Missouri to Florence Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Florence Airport?

  • How old do you have to be to fly from Missouri to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Missouri to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Florence, South Carolina

Compare and see reviews for airlines that fly from Missouri to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $414Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Florence?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Missouri to Florence. momondo saves you time and could save you money on your trip.

Can I find flights from Missouri to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Missouri with this policy.

How can momondo help me find flights from Missouri to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Missouri.

I’m not ready to book a flight from Missouri to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Missouri to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Florence, South Carolina trip

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