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Cheap flights from Medellín to San Francisco from $274

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Medellín to San Francisco

Cheap round-trip flights

JetBlue Logo
1:10 pm - 11:31 pmMDE-SFO
12h 21m1 stop
JetBlue Logo
9:45 pm - 2:32 pmSFO-MDE
13h 47m1 stop
$432JetBlue
Find Deal
Sat, Nov 1 - Sat, Nov 8
JetBlue Logo
1:30 pm - 10:18 amMDE-SFO
22h 48m1 stop
JetBlue Logo
10:35 am - 2:05 pmSFO-MDE
25h 30m1 stop
$474JetBlue
Find Deal
Sun, Sep 28 - Fri, Oct 10
Avianca Logo
2:10 pm - 10:45 pmMDE-SFO
10h 35m1 stop
Avianca Logo
12:05 am - 12:40 pmSFO-MDE
10h 35m1 stop
$484Avianca
Find Deal
Tue, Sep 9 - Sun, Oct 19
Avianca Logo
2:10 pm - 10:45 pmMDE-SFO
10h 35m1 stop
Avianca Logo
12:05 am - 6:01 pmSFO-MDE
15h 56m2 stops
$489Avianca
Find Deal
Tue, Sep 9 - Sun, Sep 14
American Airlines Logo
6:00 am - 10:54 pmMDE-SFO
18h 54m1 stop
American Airlines Logo
8:00 am - 8:15 pmSFO-MDE
10h 15m1 stop
$528American Airlines
Find Deal
Mon, Sep 8 - Wed, Oct 8
American Airlines Logo
6:00 am - 10:48 pmMDE-SFO
18h 48m2 stops
American Airlines Logo
11:10 am - 12:50 pmSFO-MDE
23h 40m1 stop
$530American Airlines
Find Deal
Thu, Sep 11 - Sat, Sep 27
Copa Airlines Logo
9:15 am - 11:39 pmMDE-SFO
16h 24m1 stop
Copa Airlines Logo
1:31 am - 1:25 pmSFO-MDE
9h 54m1 stop
$539Copa Airlines
Find Deal
Thu, Oct 16 - Wed, Oct 22
United Airlines Logo
10:45 am - 7:35 amMDE-SFO
23h 50m1 stop
United Airlines Logo
2:42 pm - 5:42 amSFO-MDE
12h 00m1 stop
$543United Airlines
Find Deal
Thu, Nov 20 - Mon, Dec 8
Copa Airlines Logo
12:45 pm - 11:25 pmMDE-SFO
12h 40m1 stop
Copa Airlines Logo
1:30 am - 2:44 pmSFO-MDE
11h 14m1 stop
$548Copa Airlines
Find Deal
Mon, Sep 15 - Wed, Sep 17
United Airlines Logo
9:45 am - 10:20 pmMDE-SFO
14h 35m1 stop
United Airlines Logo
11:59 pm - 9:10 pmSFO-MDE
19h 11m1 stop
$551United Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 12

JetBlue flights from Medellín to San Francisco

Our best JetBlue deals on Medellín to San Francisco flight tickets
JetBlue
Nov 1
MDE1:10 pmMedellín Jose Maria Cordova Intl
12h 21m
1 stop
SFO11:31 pmSan Francisco
Nov 8
SFO9:45 pmSan Francisco
13h 47m
1 stop
MDE2:32 pmMedellín Jose Maria Cordova Intl
$432
Find similar
JetBlue
Sep 28
MDE1:30 pmMedellín Jose Maria Cordova Intl
22h 48m
1 stop
SFO10:18 amSan Francisco
Oct 10
SFO10:35 amSan Francisco
25h 30m
1 stop
MDE2:05 pmMedellín Jose Maria Cordova Intl
$474
Find similar
JetBlue
Oct 1
MDE1:30 pmMedellín Jose Maria Cordova Intl
11h 40m
1 stop
SFO11:10 pmSan Francisco
Oct 8
SFO11:20 pmSan Francisco
12h 45m
1 stop
MDE2:05 pmMedellín Jose Maria Cordova Intl
$485
Find similar

Avianca flights from Medellín to San Francisco

Our best Avianca deals on Medellín to San Francisco flight tickets
Avianca
Sep 9
MDE2:10 pmMedellín Jose Maria Cordova Intl
10h 35m
1 stop
SFO10:45 pmSan Francisco
Oct 19
SFO12:05 amSan Francisco
10h 35m
1 stop
MDE12:40 pmMedellín Jose Maria Cordova Intl
$484
Find similar
Avianca
Sep 9
MDE2:10 pmMedellín Jose Maria Cordova Intl
10h 35m
1 stop
SFO10:45 pmSan Francisco
Sep 14
SFO12:05 amSan Francisco
15h 56m
2 stops
MDE6:01 pmMedellín Jose Maria Cordova Intl
$489
Find similar
Avianca
Sep 9
MDE9:38 pmMedellín Jose Maria Cordova Intl
16h 57m
2 stops
SFO12:35 pmSan Francisco
Sep 14
SFO12:05 amSan Francisco
15h 21m
2 stops
MDE5:26 pmMedellín Jose Maria Cordova Intl
$494
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medellín to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 3, 2025.
Use the filters below to find and compare flights from Medellín to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sat 11/1

1:10 pm-11:31 pm

1 stop12h 21m

San Francisco

Sat 11/8

9:45 pm-2:32 pm

1 stop13h 47m

$432

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sun 9/28

1:30 pm-10:18 am

1 stop22h 48m

San Francisco

Fri 10/10

10:35 am-2:05 pm

1 stop25h 30m

$474

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 9/9

2:10 pm-10:45 pm

1 stop10h 35m

San Francisco

Sun 10/19

12:05 am-12:40 pm

1 stop10h 35m

$484

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 9/9

2:10 pm-10:45 pm

1 stop10h 35m

San Francisco

Sun 9/14

12:05 am-6:01 pm

2 stops15h 56m

$489

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 9/8

6:00 am-10:54 pm

1 stop18h 54m

San Francisco

Wed 10/8

8:00 am-8:15 pm

1 stop10h 15m

$528

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 9/11

6:00 am-10:48 pm

2 stops18h 48m

San Francisco

Sat 9/27

11:10 am-12:50 pm

1 stop23h 40m

$530

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 10/16

9:15 am-11:39 pm

1 stop16h 24m

San Francisco

Wed 10/22

1:31 am-1:25 pm

1 stop9h 54m

$539

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 11/20

10:45 am-7:35 am

1 stop23h 50m

San Francisco

Mon 12/8

2:42 pm-5:42 am

1 stop12h 00m

$543

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 9/15

12:45 pm-11:25 pm

1 stop12h 40m

San Francisco

Wed 9/17

1:30 am-2:44 pm

1 stop11h 14m

$548

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Fri 10/3

9:45 am-10:20 pm

1 stop14h 35m

San Francisco

Sun 10/12

11:59 pm-9:10 pm

1 stop19h 11m

$551

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Medellín to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of May, then flying in June is also cheap. Prices for this month can be found on momondo for an average of $532.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Medellín to San Francisco is on a Thursday when prices can be found for as low as $529. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $724.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Medellín to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $624. Flights in the evening are often more expensive with an average ticket price of $724.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Medellín when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $572 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Medellín for as low as $515 on momondo.

Cheap Medellín to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín to San Francisco

Direct flights

None
There are no direct flights from Medellín to San Francisco. There are no popular flight routes from Medellín to San Francisco.
Search flight deals

  • How far is Medellín to San Francisco by plane?

    Medellín and San Francisco are 3650.0 mi apart from one another. By plane, this route typically takes 10h 35m.

  • When did momondo last update prices for flights from Medellín to San Francisco Airport?

    Prices for flights from Medellín to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Medellín to San Francisco Airport?

  • How old do you have to be to fly from Medellín to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medellín to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Medellín to San Francisco

Compare and see reviews for airlines that fly from Medellín to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $314Free CancellationRating
7.6
1,525 reviews
Search Copa Airlines flights
AviancaPriceFrom $386Free CancellationRating
6.7
2,427 reviews
Search Avianca flights
United AirlinesPriceFrom $440Free CancellationRating
7.4
8,937 reviews
Search United Airlines flights
American AirlinesPriceFrom $587Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Calistoga
Hayward
Bodega Bay
Roseville
Santa Clara
Big Sur
Daly City
Fremont
Berkeley
Walnut Creek
Half Moon Bay
Vallejo
South San Francisco
Redwood City
Pacific Grove
Pacifica

Why use momondo?

Why should I use momondo to find a flight deal from Medellín to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Medellín to San Francisco for you.

Can I find flights from Medellín to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Medellín on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Medellín to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medellín to San Francisco.

I’m not ready to book a flight from Medellín to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Medellín and alert you when they change.

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