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Cheap flights from Medellín to San Francisco from $358

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Medellín to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
1:30 pm - 11:19 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
11h 49m1 stop Fort Lauderdale
JetBlue Logo
11:10 pm - 2:30 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
13h 20m1 stop Fort Lauderdale
$547JetBlue
Tue, Oct 6 - Sat, Oct 10
American Airlines Logo
6:00 am - 10:56 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
18h 56m2 stops Miami Philadelphia
American Airlines Logo
10:46 pm - 8:15 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
19h 29m2 stops Chicago O'Hare Intl Miami
$653American Airlines
Tue, Sep 15 - Tue, Sep 29
American Airlines Logo
6:00 am - 11:59 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
19h 59m1 stop Miami
American Airlines Logo
10:46 pm - 8:15 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
19h 29m2 stops Chicago O'Hare Intl Miami
$653American Airlines
Tue, Sep 15 - Tue, Sep 29
American Airlines Logo
1:53 pm - 11:59 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
12h 06m1 stop Miami
American Airlines Logo
9:35 am - 12:48 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
25h 13m1 stop Miami
$665American Airlines
Tue, Sep 15 - Tue, Sep 29
Avianca Logo
2:10 pm - 10:35 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
10h 25m1 stop San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 1:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
11h 15m1 stop San Salvador El Salvador Intl
$680Avianca
Tue, Oct 6 - Sat, Oct 10
Avianca Logo
2:10 pm - 10:35 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
10h 25m1 stop San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 1:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
11h 15m1 stop San Salvador El Salvador Intl
$680Avianca
Tue, Sep 15 - Fri, Sep 25
United Airlines Logo
9:45 am - 7:58 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
12h 13m1 stop Houston George Bush Intcntl
United Airlines Logo
6:35 pm - 10:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
24h 35m1 stop Houston George Bush Intcntl
$755United Airlines
Fri, Oct 30 - Thu, Nov 12
United Airlines Logo
9:45 am - 10:42 amMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
26h 57m1 stop Houston George Bush Intcntl
United Airlines Logo
6:30 pm - 9:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
24h 40m1 stop Houston George Bush Intcntl
$759United Airlines
Wed, Sep 16 - Fri, Sep 18
Copa Airlines Logo
8:35 am - 11:40 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
17h 05m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:21 pm - 8:15 amSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
9h 54m1 stop Panama City Tocumen Intl
$776Copa Airlines
Mon, Aug 31 - Thu, Sep 10
Copa Airlines Logo
12:40 pm - 11:40 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
13h 00m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:12 am - 2:45 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
11h 33m1 stop Panama City Tocumen Intl
$776Copa Airlines
Sat, Sep 5 - Fri, Sep 25

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American Airlines flights from Medellín to San Francisco

Our best American Airlines deals on Medellín to San Francisco flight tickets
American Airlines
Sep 12
MDE6:00 amMedellín Jose Maria Cordova Intl
19h 28m
2 stops
SFO11:28 pmSan Francisco
Sep 19
SFO10:46 pmSan Francisco
19h 29m
2 stops
MDE8:15 pmMedellín Jose Maria Cordova Intl
$653
American Airlines
Sep 15
MDE1:53 pmMedellín Jose Maria Cordova Intl
12h 06m
1 stop
SFO11:59 pmSan Francisco
Sep 29
SFO9:35 amSan Francisco
25h 13m
1 stop
MDE12:48 pmMedellín Jose Maria Cordova Intl
$665
American Airlines
Sep 10
MDE6:00 amMedellín Jose Maria Cordova Intl
19h 59m
1 stop
SFO11:59 pmSan Francisco
Sep 14
SFO10:54 pmSan Francisco
19h 21m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
$672

United Airlines flights from Medellín to San Francisco

Our best United Airlines deals on Medellín to San Francisco flight tickets
United Airlines
Sep 16
MDE9:45 amMedellín Jose Maria Cordova Intl
26h 57m
1 stop
SFO10:42 amSan Francisco
Sep 18
SFO6:30 pmSan Francisco
24h 40m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
$759
United Airlines
Sep 20
MDE9:45 amMedellín Jose Maria Cordova Intl
16h 42m
1 stop
SFO12:27 amSan Francisco
Sep 26
SFO2:25 pmSan Francisco
28h 45m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
$762
United Airlines
Aug 14
MDE9:45 amMedellín Jose Maria Cordova Intl
28h 29m
1 stop
SFO12:14 pmSan Francisco
Aug 16
SFO12:45 amSan Francisco
18h 25m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
$814

momondo Fare Finder

 
Customize your flight search to find flights from Medellín to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Medellín to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Tue 10/6

1:30 pm-11:19 pm

1 stop11h 49m

San Francisco

Sat 10/10

11:10 pm-2:30 pm

1 stop13h 20m

$547

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Tue 9/15

6:00 am-10:56 pm

2 stops18h 56m

San Francisco

Tue 9/29

10:46 pm-8:15 pm

2 stops19h 29m

$653

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Tue 9/15

6:00 am-11:59 pm

1 stop19h 59m

San Francisco

Tue 9/29

10:46 pm-8:15 pm

2 stops19h 29m

$653

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Tue 9/15

1:53 pm-11:59 pm

1 stop12h 06m

San Francisco

Tue 9/29

9:35 am-12:48 pm

1 stop25h 13m

$665
Quickest round-trip

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Tue 10/6

2:10 pm-10:35 pm

1 stop10h 25m

San Francisco

Sat 10/10

11:55 pm-1:10 pm

1 stop11h 15m

$680

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Tue 9/15

2:10 pm-10:35 pm

1 stop10h 25m

San Francisco

Fri 9/25

11:55 pm-1:10 pm

1 stop11h 15m

$680

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Fri 10/30

9:45 am-7:58 pm

1 stop12h 13m

San Francisco

Thu 11/12

6:35 pm-10:10 pm

1 stop24h 35m

$755

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Wed 9/16

9:45 am-10:42 am

1 stop26h 57m

San Francisco

Fri 9/18

6:30 pm-9:10 pm

1 stop24h 40m

$759

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Mon 8/31

8:35 am-11:40 pm

1 stop17h 05m

San Francisco

Thu 9/10

8:21 pm-8:15 am

1 stop9h 54m

$776

MedellínSan Francisco

MDE Medellín Jose Maria Cordova Intl - SFO San Francisco

MDESFO

Medellín Jose Maria Cordova Intl

Sat 9/5

12:40 pm-11:40 pm

1 stop13h 00m

San Francisco

Fri 9/25

1:12 am-2:45 pm

1 stop11h 33m

$776

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Medellín to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Medellín and San Francisco?

Prices are currently typical for flights on this route.

Typical prices usually range from $547 to $699.
The lowest price recently found on this route was $547.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in April is also cheap. Prices for this month can be found on momondo for an average of $489.

How far in advance should I book a flight from Medellín to San Francisco?

You are more likely to see cheaper flights to San Francisco from Medellín when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $576 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Medellín for as low as $325 on momondo.

Cheap Medellín to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín to San Francisco

Fastest flight time

10h 44m

Direct flights

None
The fastest flight from Medellín to San Francisco takes 10h 44m
There are no direct flights from Medellín to San Francisco. There are no popular flight routes from Medellín to San Francisco.
Search flight deals

Frequently asked questions about flying from Medellín to San Francisco

  • How far is Medellín to San Francisco by plane?

    Medellín and San Francisco are 3649.2 mi apart from one another. By plane, this route typically takes 10h 44m.

  • When did momondo last update prices for flights from Medellín to San Francisco Airport?

    Prices for flights from Medellín to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Medellín to San Francisco Airport?

  • How old do you have to be to fly from Medellín to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medellín to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Medellín to San Francisco

Compare and see reviews for airlines that fly from Medellín to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $222Free CancellationRating
7.4
10,103 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $453Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $492Free CancellationRating
7.1
11,902 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Fremont
Berkeley
Bodega Bay
Hayward
Walnut Creek
Santa Clara
Vallejo
Roseville
Sonoma
Salinas
Sunnyvale
Milpitas
Daly City
Burlingame
Marina
Palo Alto

Why use momondo?

Why should I use momondo to find a flight deal from Medellín to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Medellín to San Francisco for you.

Can I find flights from Medellín to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Medellín on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Medellín to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medellín to San Francisco.

I’m not ready to book a flight from Medellín to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Medellín and alert you when they change.

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