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Cheap flights from Medellín to San Francisco from $244

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 11/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
2:25 pm - 11:30 pmMDE-SFO
12h 05m1 stop
JetBlue Logo
11:59 pm - 2:45 pmSFO-MDE
11h 46m1 stop
$487JetBlue
Find Deal
Sat, Jan 10 - Thu, Jan 22
JetBlue Logo
2:25 pm - 11:30 pmMDE-SFO
12h 05m1 stop
JetBlue Logo
10:40 pm - 1:20 pmSFO-MDE
11h 40m1 stop
$503JetBlue
Find Deal
Wed, Feb 4 - Sat, Feb 21
Copa Airlines Logo
8:37 am - 11:17 pmMDE-SFO
17h 40m1 stop
Copa Airlines Logo
12:36 am - 2:45 pmSFO-MDE
11h 09m1 stop
$537Copa Airlines
Find Deal
Tue, Nov 11 - Mon, Nov 17
Copa Airlines Logo
6:24 am - 11:17 pmMDE-SFO
19h 53m1 stop
Copa Airlines Logo
12:36 am - 2:45 pmSFO-MDE
11h 09m1 stop
$538Copa Airlines
Find Deal
Thu, Dec 4 - Wed, Dec 10
United Airlines Logo
1:15 am - 9:11 pmMDE-SFO
22h 56m1 stop
United Airlines Logo
7:02 am - 5:42 amSFO-MDE
19h 40m1 stop
$540United Airlines
Find Deal
Fri, Dec 19 - Tue, Dec 30
Avianca Logo
2:10 pm - 11:40 pmMDE-SFO
11h 30m1 stop
Avianca Logo
2:20 pm - 2:05 amSFO-MDE
9h 45m1 stop
$541Avianca
Find Deal
Tue, Mar 24 - Thu, Apr 2
Avianca Logo
2:10 pm - 9:50 pmMDE-SFO
10h 40m1 stop
Avianca Logo
11:10 pm - 12:55 pmSFO-MDE
10h 45m1 stop
$542Avianca
Find Deal
Fri, Jan 23 - Sat, Feb 14
United Airlines Logo
1:15 am - 9:11 pmMDE-SFO
22h 56m1 stop
United Airlines Logo
7:11 pm - 10:05 pmSFO-MDE
23h 54m1 stop
$543United Airlines
Find Deal
Fri, Dec 19 - Wed, Dec 31
American Airlines Logo
5:50 am - 10:52 pmMDE-SFO
19h 02m2 stops
American Airlines Logo
12:21 am - 7:50 pmSFO-MDE
17h 29m2 stops
$562American Airlines
Find Deal
Wed, Apr 15 - Sat, Apr 18
American Airlines Logo
12:20 am - 4:32 pmMDE-SFO
18h 12m2 stops
American Airlines Logo
1:27 pm - 12:40 pmSFO-MDE
21h 13m1 stop
$563American Airlines
Find Deal
Mon, Mar 30 - Sun, Apr 19

JetBlue flights from Medellín to San Francisco

Our best JetBlue deals on Medellín to San Francisco flight tickets
JetBlue
Jan 10
MDE2:25 pmMedellín Jose Maria Cordova Intl
12h 05m
1 stop
SFO11:30 pmSan Francisco
Jan 22
SFO11:59 pmSan Francisco
11h 46m
1 stop
MDE2:45 pmMedellín Jose Maria Cordova Intl
$487
Find similar
JetBlue
Feb 4
MDE2:25 pmMedellín Jose Maria Cordova Intl
12h 05m
1 stop
SFO11:30 pmSan Francisco
Feb 21
SFO10:40 pmSan Francisco
11h 40m
1 stop
MDE1:20 pmMedellín Jose Maria Cordova Intl
$503
Find similar
JetBlue
Nov 11
MDE2:10 pmMedellín Jose Maria Cordova Intl
12h 21m
1 stop
SFO11:31 pmSan Francisco
Nov 18
SFO9:44 pmSan Francisco
13h 48m
1 stop
MDE2:32 pmMedellín Jose Maria Cordova Intl
$545
Find similar

Copa Airlines flights from Medellín to San Francisco

Our best Copa Airlines deals on Medellín to San Francisco flight tickets
Copa Airlines
Nov 11
MDE8:37 amMedellín Jose Maria Cordova Intl
17h 40m
1 stop
SFO11:17 pmSan Francisco
Nov 17
SFO12:36 amSan Francisco
11h 09m
1 stop
MDE2:45 pmMedellín Jose Maria Cordova Intl
$537
Find similar
Copa Airlines
Dec 4
MDE6:24 amMedellín Jose Maria Cordova Intl
19h 53m
1 stop
SFO11:17 pmSan Francisco
Dec 10
SFO12:36 amSan Francisco
11h 09m
1 stop
MDE2:45 pmMedellín Jose Maria Cordova Intl
$538
Find similar
Copa Airlines
Nov 9
MDE3:15 pmMedellín Jose Maria Cordova Intl
11h 02m
1 stop
SFO11:17 pmSan Francisco
Dec 10
SFO12:36 amSan Francisco
10h 39m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
$568
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medellín to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Medellín to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sat 1/10

2:25 pm-11:30 pm

1 stop12h 05m

San Francisco

Thu 1/22

11:59 pm-2:45 pm

1 stop11h 46m

$487

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 2/4

2:25 pm-11:30 pm

1 stop12h 05m

San Francisco

Sat 2/21

10:40 pm-1:20 pm

1 stop11h 40m

$503

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 11/11

8:37 am-11:17 pm

1 stop17h 40m

San Francisco

Mon 11/17

12:36 am-2:45 pm

1 stop11h 09m

$537

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 12/4

6:24 am-11:17 pm

1 stop19h 53m

San Francisco

Wed 12/10

12:36 am-2:45 pm

1 stop11h 09m

$538

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Fri 12/19

1:15 am-9:11 pm

1 stop22h 56m

San Francisco

Tue 12/30

7:02 am-5:42 am

1 stop19h 40m

$540

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 3/24

2:10 pm-11:40 pm

1 stop11h 30m

San Francisco

Thu 4/2

2:20 pm-2:05 am

1 stop9h 45m

$541

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Fri 1/23

2:10 pm-9:50 pm

1 stop10h 40m

San Francisco

Sat 2/14

11:10 pm-12:55 pm

1 stop10h 45m

$542

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Fri 12/19

1:15 am-9:11 pm

1 stop22h 56m

San Francisco

Wed 12/31

7:11 pm-10:05 pm

1 stop23h 54m

$543

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 4/15

5:50 am-10:52 pm

2 stops19h 02m

San Francisco

Sat 4/18

12:21 am-7:50 pm

2 stops17h 29m

$562

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 3/30

12:20 am-4:32 pm

2 stops18h 12m

San Francisco

Sun 4/19

1:27 pm-12:40 pm

1 stop21h 13m

$563

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Medellín to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of May, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $532.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Medellín to San Francisco is on a Thursday when prices can be found for as low as $529. The most expensive day to fly to San Francisco is Monday, with ticket prices averaging around $724.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Medellín to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $624. Flights in the evening are often more expensive with an average ticket price of $724.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Medellín when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $576 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Medellín for as low as $507 on momondo.

Cheap Medellín to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín to San Francisco

Direct flights

None
There are no direct flights from Medellín to San Francisco. There are no popular flight routes from Medellín to San Francisco.
Search flight deals

  • How far is Medellín to San Francisco by plane?

    Medellín and San Francisco are 3650.0 mi apart from one another. By plane, this route typically takes 10h 40m.

  • When did momondo last update prices for flights from Medellín to San Francisco Airport?

    Prices for flights from Medellín to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Medellín to San Francisco Airport?

  • How old do you have to be to fly from Medellín to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medellín to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Medellín to San Francisco

Compare and see reviews for airlines that fly from Medellín to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $285Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
AviancaPriceFrom $386Free CancellationRating
6.6
2,464 reviews
Search Avianca flights
United AirlinesPriceFrom $440Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights
American AirlinesPriceFrom $641Free CancellationRating
7.2
11,031 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Calistoga
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Vallejo
Walnut Creek
Half Moon Bay
Salinas
Turlock
Livermore
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Medellín to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Medellín to San Francisco for you.

Can I find flights from Medellín to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Medellín on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Medellín to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medellín to San Francisco.

I’m not ready to book a flight from Medellín to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Medellín and alert you when they change.

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