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Cheap flights from Medellín to San Francisco from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 5/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Medellín to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 11:01 pm
MDE
-
SFO
19h 01m
1 stop
American Airlines Logo
6:15 am - 8:15 pm
SFO
-
MDE
12h 00m
1 stop
$440American Airlines
Wed, Apr 29 - Wed, May 6
American Airlines Logo
6:00 am - 11:15 pm
MDE
-
SFO
19h 15m
2 stops
American Airlines Logo
6:15 am - 8:15 pm
SFO
-
MDE
12h 00m
1 stop
$445American Airlines
Wed, Apr 15 - Tue, Apr 21
American Airlines Logo
6:00 am - 11:15 pm
MDE
-
SFO
19h 15m
2 stops
American Airlines Logo
12:59 am - 8:15 pm
SFO
-
MDE
17h 16m
2 stops
$452American Airlines
Wed, Apr 15 - Mon, Apr 20
Copa Airlines Logo
9:15 am - 11:40 pm
MDE
-
SFO
16h 25m
1 stop
Copa Airlines Logo
8:37 pm - 2:15 pm
SFO
-
MDE
15h 38m
1 stop
$465Copa Airlines
Tue, Apr 7 - Thu, Apr 9
United Airlines Logo
9:45 am - 6:58 pm
MDE
-
SFO
11h 13m
1 stop
United Airlines Logo
11:59 pm - 9:10 pm
SFO
-
MDE
19h 11m
1 stop
$467United Airlines
Thu, Apr 16 - Mon, Apr 20
United Airlines Logo
9:45 am - 7:15 am
MDE
-
SFO
23h 30m
1 stop
United Airlines Logo
2:28 pm - 9:10 pm
SFO
-
MDE
28h 42m
1 stop
$468United Airlines
Thu, Apr 30 - Fri, May 15
United Airlines Logo
9:45 am - 12:18 pm
MDE
-
SFO
28h 33m
1 stop
United Airlines Logo
5:00 am - 9:10 pm
SFO
-
MDE
14h 10m
1 stop
$469United Airlines
Thu, Apr 16 - Mon, Apr 20
Avianca Logo
10:40 am - 10:35 pm
MDE
-
SFO
13h 55m
2 stops
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$470Avianca
Tue, Apr 21 - Mon, Apr 27
Avianca Logo
9:30 am - 10:35 pm
MDE
-
SFO
15h 05m
2 stops
Avianca Logo
11:55 pm - 4:00 pm
SFO
-
MDE
14h 05m
2 stops
$477Avianca
Tue, Apr 21 - Mon, Apr 27
Avianca Logo
10:15 am - 10:35 pm
MDE
-
SFO
14h 20m
2 stops
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$479Avianca
Wed, May 20 - Wed, May 27

American Airlines flights from Medellín to San Francisco

Our best American Airlines deals on Medellín to San Francisco flight tickets
American Airlines
Apr 29
MDE6:00 amMedellín Jose Maria Cordova Intl
19h 01m
1 stop
SFO11:01 pmSan Francisco
May 6
SFO6:15 amSan Francisco
12h 00m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
$440
American Airlines
Apr 15
MDE6:00 amMedellín Jose Maria Cordova Intl
19h 15m
2 stops
SFO11:15 pmSan Francisco
Apr 21
SFO6:15 amSan Francisco
12h 00m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
$445
American Airlines
Apr 15
MDE6:00 amMedellín Jose Maria Cordova Intl
19h 15m
2 stops
SFO11:15 pmSan Francisco
Apr 20
SFO12:59 amSan Francisco
17h 16m
2 stops
MDE8:15 pmMedellín Jose Maria Cordova Intl
$452

Avianca flights from Medellín to San Francisco

Our best Avianca deals on Medellín to San Francisco flight tickets
Avianca
Apr 21
MDE10:40 amMedellín Jose Maria Cordova Intl
13h 55m
2 stops
SFO10:35 pmSan Francisco
Apr 27
SFO11:55 pmSan Francisco
11h 15m
1 stop
MDE1:10 pmMedellín Jose Maria Cordova Intl
$470
Avianca
Apr 21
MDE9:30 amMedellín Jose Maria Cordova Intl
15h 05m
2 stops
SFO10:35 pmSan Francisco
Apr 27
SFO11:55 pmSan Francisco
14h 05m
2 stops
MDE4:00 pmMedellín Jose Maria Cordova Intl
$477
Avianca
May 20
MDE10:15 amMedellín Jose Maria Cordova Intl
14h 20m
2 stops
SFO10:35 pmSan Francisco
May 27
SFO11:55 pmSan Francisco
11h 15m
1 stop
MDE1:10 pmMedellín Jose Maria Cordova Intl
$479

momondo Fare Finder

 
Customize your flight search to find flights from Medellín to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Medellín to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 4/29

6:00 am-11:01 pm

1 stop19h 01m

San Francisco

Wed 5/6

6:15 am-8:15 pm

1 stop12h 00m

$440

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 4/15

6:00 am-11:15 pm

2 stops19h 15m

San Francisco

Tue 4/21

6:15 am-8:15 pm

1 stop12h 00m

$445

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 4/15

6:00 am-11:15 pm

2 stops19h 15m

San Francisco

Mon 4/20

12:59 am-8:15 pm

2 stops17h 16m

$452

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 4/7

9:15 am-11:40 pm

1 stop16h 25m

San Francisco

Thu 4/9

8:37 pm-2:15 pm

1 stop15h 38m

$465

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 4/16

9:45 am-6:58 pm

1 stop11h 13m

San Francisco

Mon 4/20

11:59 pm-9:10 pm

1 stop19h 11m

$467

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 4/30

9:45 am-7:15 am

1 stop23h 30m

San Francisco

Fri 5/15

2:28 pm-9:10 pm

1 stop28h 42m

$468

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 4/16

9:45 am-12:18 pm

1 stop28h 33m

San Francisco

Mon 4/20

5:00 am-9:10 pm

1 stop14h 10m

$469
Quickest round-trip

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 4/21

10:40 am-10:35 pm

2 stops13h 55m

San Francisco

Mon 4/27

11:55 pm-1:10 pm

1 stop11h 15m

$470

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 4/21

9:30 am-10:35 pm

2 stops15h 05m

San Francisco

Mon 4/27

11:55 pm-4:00 pm

2 stops14h 05m

$477

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 5/20

10:15 am-10:35 pm

2 stops14h 20m

San Francisco

Wed 5/27

11:55 pm-1:10 pm

1 stop11h 15m

$479

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Medellín to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of February, then flying in April is also cheap. Prices for this month can be found on momondo for an average of $489.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Medellín when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $545 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Medellín for as low as $472 on momondo.

Cheap Medellín to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín to San Francisco

Fastest flight time

11h 13m

Direct flights

None
The fastest flight from Medellín to San Francisco takes 11h 13m
There are no direct flights from Medellín to San Francisco. There are no popular flight routes from Medellín to San Francisco.
Search flight deals

  • How far is Medellín to San Francisco by plane?

    Medellín and San Francisco are 3650.0 mi apart from one another. By plane, this route typically takes 11h 13m.

  • When did momondo last update prices for flights from Medellín to San Francisco Airport?

    Prices for flights from Medellín to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Medellín to San Francisco Airport?

  • How old do you have to be to fly from Medellín to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medellín to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Medellín to San Francisco

Compare and see reviews for airlines that fly from Medellín to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $208Free CancellationRating
6.5
2,503 reviews
Search Avianca flights
United AirlinesPriceFrom $440Free CancellationRating
7.4
9,454 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $453Free CancellationRating
7.5
1,573 reviews
Search Copa Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Half Moon Bay
Daly City
Milpitas
Pacific Grove
South San Francisco

Why use momondo?

Why should I use momondo to find a flight deal from Medellín to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Medellín to San Francisco for you.

Can I find flights from Medellín to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Medellín on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Medellín to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medellín to San Francisco.

I’m not ready to book a flight from Medellín to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Medellín and alert you when they change.

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