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Cheap flights from Medellín to San Francisco from $321

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 7/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Medellín to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 8:18 pm
MDE
-
SFO
16h 18m
1 stop
American Airlines Logo
9:35 pm - 8:15 pm
SFO
-
MDE
20h 40m
1 stop
$648American Airlines
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
6:00 am - 11:45 pm
MDE
-
SFO
19h 45m
2 stops
American Airlines Logo
3:46 pm - 12:50 pm
SFO
-
MDE
19h 04m
2 stops
$653American Airlines
Wed, Aug 19 - Mon, Aug 31
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$672Avianca
Mon, Jul 27 - Sat, Aug 8
Copa Airlines Logo
10:35 am - 11:40 pm
MDE
-
SFO
15h 05m
1 stop
Copa Airlines Logo
1:12 am - 2:15 pm
SFO
-
MDE
11h 03m
1 stop
$675Copa Airlines
Wed, Aug 12 - Sun, Aug 16
Copa Airlines Logo
3:10 pm - 11:40 pm
MDE
-
SFO
10h 30m
1 stop
Copa Airlines Logo
8:21 pm - 2:45 pm
SFO
-
MDE
16h 24m
1 stop
$676Copa Airlines
Thu, Aug 6 - Tue, Aug 25
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$677Avianca
Tue, Aug 4 - Thu, Aug 27
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$678Avianca
Tue, Aug 4 - Thu, Aug 27
Copa Airlines Logo
8:35 am - 11:40 pm
MDE
-
SFO
17h 05m
1 stop
Copa Airlines Logo
8:21 pm - 10:50 pm
SFO
-
MDE
24h 29m
1 stop
$679Copa Airlines
Thu, Aug 6 - Thu, Aug 27
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$680Avianca
Mon, Aug 17 - Thu, Aug 27
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$681Avianca
Mon, Jul 27 - Sat, Aug 8

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Copa Airlines flights from Medellín to San Francisco

Our best Copa Airlines deals on Medellín to San Francisco flight tickets
Copa Airlines
Aug 12
MDE10:35 amMedellín Jose Maria Cordova Intl
15h 05m
1 stop
SFO11:40 pmSan Francisco
Aug 16
SFO1:12 amSan Francisco
11h 03m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
$675
Copa Airlines
Aug 6
MDE3:10 pmMedellín Jose Maria Cordova Intl
10h 30m
1 stop
SFO11:40 pmSan Francisco
Aug 25
SFO8:21 pmSan Francisco
16h 24m
1 stop
MDE2:45 pmMedellín Jose Maria Cordova Intl
$676
Copa Airlines
Aug 6
MDE8:35 amMedellín Jose Maria Cordova Intl
17h 05m
1 stop
SFO11:40 pmSan Francisco
Aug 27
SFO8:21 pmSan Francisco
24h 29m
1 stop
MDE10:50 pmMedellín Jose Maria Cordova Intl
$679

American Airlines flights from Medellín to San Francisco

Our best American Airlines deals on Medellín to San Francisco flight tickets
American Airlines
Aug 18
MDE6:00 amMedellín Jose Maria Cordova Intl
16h 18m
1 stop
SFO8:18 pmSan Francisco
Aug 25
SFO9:35 pmSan Francisco
20h 40m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
$648
American Airlines
Aug 19
MDE6:00 amMedellín Jose Maria Cordova Intl
19h 45m
2 stops
SFO11:45 pmSan Francisco
Aug 31
SFO3:46 pmSan Francisco
19h 04m
2 stops
MDE12:50 pmMedellín Jose Maria Cordova Intl
$653
American Airlines
Jul 2
MDE12:30 amMedellín Jose Maria Cordova Intl
17h 35m
2 stops
SFO4:05 pmSan Francisco
Jul 13
SFO8:15 amSan Francisco
13h 33m
2 stops
MDE11:48 pmMedellín Jose Maria Cordova Intl
$690

momondo Fare Finder

 
Customize your flight search to find flights from Medellín to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Medellín to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 8/18

6:00 am-8:18 pm

1 stop16h 18m

San Francisco

Tue 8/25

9:35 pm-8:15 pm

1 stop20h 40m

$648

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 8/19

6:00 am-11:45 pm

2 stops19h 45m

San Francisco

Mon 8/31

3:46 pm-12:50 pm

2 stops19h 04m

$653
Quickest round-trip

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 7/27

2:10 pm-10:35 pm

1 stop10h 25m

San Francisco

Sat 8/8

11:55 pm-1:10 pm

1 stop11h 15m

$672

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 8/12

10:35 am-11:40 pm

1 stop15h 05m

San Francisco

Sun 8/16

1:12 am-2:15 pm

1 stop11h 03m

$675

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 8/6

3:10 pm-11:40 pm

1 stop10h 30m

San Francisco

Tue 8/25

8:21 pm-2:45 pm

1 stop16h 24m

$676

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 8/4

2:10 pm-10:35 pm

1 stop10h 25m

San Francisco

Thu 8/27

11:55 pm-1:10 pm

1 stop11h 15m

$677

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 8/4

2:10 pm-10:35 pm

1 stop10h 25m

San Francisco

Thu 8/27

11:55 pm-1:10 pm

1 stop11h 15m

$678

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 8/6

8:35 am-11:40 pm

1 stop17h 05m

San Francisco

Thu 8/27

8:21 pm-10:50 pm

1 stop24h 29m

$679

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 8/17

2:10 pm-10:35 pm

1 stop10h 25m

San Francisco

Thu 8/27

11:55 pm-1:10 pm

1 stop11h 15m

$680

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 7/27

2:10 pm-10:35 pm

1 stop10h 25m

San Francisco

Sat 8/8

11:55 pm-1:10 pm

1 stop11h 15m

$681

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Medellín to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Medellín and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $180.

How far in advance should I book a flight from Medellín to San Francisco?

You are more likely to see cheaper flights to San Francisco from Medellín when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $560 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Medellín for as low as $430 on momondo.

Cheap Medellín to San Francisco flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín to San Francisco

Fastest flight time

10h 30m

Direct flights

None
The fastest flight from Medellín to San Francisco takes 10h 30m
There are no direct flights from Medellín to San Francisco. There are no popular flight routes from Medellín to San Francisco.
Search flight deals

Frequently asked questions about flying from Medellín to San Francisco

  • How far is Medellín to San Francisco by plane?

    Medellín and San Francisco are 3649.2 mi apart from one another. By plane, this route typically takes 10h 30m.

  • When did momondo last update prices for flights from Medellín to San Francisco Airport?

    Prices for flights from Medellín to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Medellín to San Francisco Airport?

  • How old do you have to be to fly from Medellín to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medellín to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Medellín to San Francisco

Compare and see reviews for airlines that fly from Medellín to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $405Free CancellationRating
7.4
9,866 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $453Free CancellationRating
7.6
1,569 reviews
Search Copa Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Hayward
Bodega Bay
Roseville
Fremont
Walnut Creek
Santa Clara
South San Francisco
Berkeley
Vallejo
Sunnyvale
Salinas
Big Sur
Pacific Grove
Daly City
Burlingame
Calistoga

Why use momondo?

Why should I use momondo to find a flight deal from Medellín to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Medellín to San Francisco for you.

Can I find flights from Medellín to San Francisco with flexible booking policies on momondo?

Yes. All flights to San Francisco from Medellín on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Medellín to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Medellín to San Francisco.

I’m not ready to book a flight from Medellín to San Francisco right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Francisco, momondo offers a useful price alert feature which will track prices for flights to San Francisco from Medellín and alert you when they change.

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