Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Manchester, New Hampshire to Greenville from $159

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Greenville departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Manchester, New Hampshire to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
2:17 pm - 7:29 pmMHT-GSP
5h 12m1 stop
United Airlines Logo
2:51 pm - 6:53 pmGSP-MHT
4h 02m1 stop
$350United Airlines
Find Deal
Thu, Feb 5 - Tue, Feb 17
American Airlines Logo
6:42 am - 11:25 amMHT-GSP
4h 43m1 stop
American Airlines Logo
7:16 am - 11:35 amGSP-MHT
4h 19m1 stop
$352American Airlines
Find Deal
Tue, Jan 6 - Thu, Jan 8
United Airlines Logo
2:17 pm - 11:48 pmMHT-GSP
9h 31m2 stops
United Airlines Logo
2:51 pm - 6:53 pmGSP-MHT
4h 02m1 stop
$355United Airlines
Find Deal
Thu, Feb 5 - Tue, Feb 17
American Airlines Logo
5:30 am - 10:30 amMHT-GSP
5h 00m1 stop
American Airlines Logo
10:32 am - 4:31 pmGSP-MHT
5h 59m2 stops
$357American Airlines
Find Deal
Tue, Jan 6 - Thu, Jan 8
American Airlines Logo
4:06 pm - 11:36 pmMHT-GSP
7h 30m2 stops
American Airlines Logo
6:00 am - 3:38 pmGSP-MHT
9h 38m2 stops
$362American Airlines
Find Deal
Tue, Jan 6 - Thu, Jan 8
American Airlines Logo
5:30 am - 7:12 pmMHT-GSP
13h 42m1 stop
American Airlines Logo
7:21 am - 11:50 pmGSP-MHT
16h 29m1 stop
$367American Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
American Airlines Logo
6:00 am - 10:07 amMHT-GSP
4h 07m1 stop
American Airlines Logo
10:36 am - 3:50 pmGSP-MHT
5h 14m1 stop
$387American Airlines
Find Deal
Sat, Dec 27 - Sat, Jan 3
American Airlines Logo
6:00 am - 10:27 amMHT-GSP
4h 27m1 stop
American Airlines Logo
10:32 am - 4:31 pmGSP-MHT
5h 59m2 stops
$392American Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
United Airlines Logo
2:17 pm - 11:48 pmMHT-GSP
9h 31m2 stops
United Airlines Logo
10:45 am - 6:53 pmGSP-MHT
8h 08m2 stops
$395United Airlines
Find Deal
Thu, Feb 5 - Tue, Feb 17
American Airlines Logo
11:42 am - 8:48 pmMHT-GSP
9h 06m2 stops
American Airlines Logo
3:39 pm - 11:50 pmGSP-MHT
8h 11m2 stops
$397American Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25

United Airlines flights from Manchester, New Hampshire to Greenville

Our best United Airlines deals on Manchester, New Hampshire to Greenville flight tickets
United Airlines
Feb 5
MHT2:17 pmManchester
5h 12m
1 stop
GSP7:29 pmGreenville
Feb 17
GSP2:51 pmGreenville
4h 02m
1 stop
MHT6:53 pmManchester
$350
Find similar
United Airlines
Feb 5
MHT2:17 pmManchester
9h 31m
2 stops
GSP11:48 pmGreenville
Feb 17
GSP2:51 pmGreenville
4h 02m
1 stop
MHT6:53 pmManchester
$355
Find similar
United Airlines
Feb 5
MHT2:17 pmManchester
9h 31m
2 stops
GSP11:48 pmGreenville
Feb 17
GSP10:45 amGreenville
8h 08m
2 stops
MHT6:53 pmManchester
$395
Find similar

American Airlines flights from Manchester, New Hampshire to Greenville

Our best American Airlines deals on Manchester, New Hampshire to Greenville flight tickets
American Airlines
Jan 6
MHT6:42 amManchester
4h 43m
1 stop
GSP11:25 amGreenville
Jan 8
GSP7:16 amGreenville
4h 19m
1 stop
MHT11:35 amManchester
$352
Find similar
American Airlines
Jan 6
MHT5:30 amManchester
5h 00m
1 stop
GSP10:30 amGreenville
Jan 8
GSP10:32 amGreenville
5h 59m
2 stops
MHT4:31 pmManchester
$357
Find similar
American Airlines
Jan 6
MHT4:06 pmManchester
7h 30m
2 stops
GSP11:36 pmGreenville
Jan 8
GSP6:00 amGreenville
9h 38m
2 stops
MHT3:38 pmManchester
$362
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 2/5

2:17 pm-7:29 pm

1 stop5h 12m

Greenville

Tue 2/17

2:51 pm-6:53 pm

1 stop4h 02m

$350

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 1/6

6:42 am-11:25 am

1 stop4h 43m

Greenville

Thu 1/8

7:16 am-11:35 am

1 stop4h 19m

$352

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 2/5

2:17 pm-11:48 pm

2 stops9h 31m

Greenville

Tue 2/17

2:51 pm-6:53 pm

1 stop4h 02m

$355

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 1/6

5:30 am-10:30 am

1 stop5h 00m

Greenville

Thu 1/8

10:32 am-4:31 pm

2 stops5h 59m

$357

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 1/6

4:06 pm-11:36 pm

2 stops7h 30m

Greenville

Thu 1/8

6:00 am-3:38 pm

2 stops9h 38m

$362

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

5:30 am-7:12 pm

1 stop13h 42m

Greenville

Sun 1/25

7:21 am-11:50 pm

1 stop16h 29m

$367

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 12/27

6:00 am-10:07 am

1 stop4h 07m

Greenville

Sat 1/3

10:36 am-3:50 pm

1 stop5h 14m

$387

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

6:00 am-10:27 am

1 stop4h 27m

Greenville

Sun 1/25

10:32 am-4:31 pm

2 stops5h 59m

$392

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 2/5

2:17 pm-11:48 pm

2 stops9h 31m

Greenville

Tue 2/17

10:45 am-6:53 pm

2 stops8h 08m

$395

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

11:42 am-8:48 pm

2 stops9h 06m

Greenville

Sun 1/25

3:39 pm-11:50 pm

2 stops8h 11m

$397

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Greenville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Manchester, New Hampshire averaging around $329.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Manchester, New Hampshire. The lowest ticket price found for a Tuesday departure recently was $322. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $396. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Manchester, New Hampshire to Greenville during this time can be as low as $326. Flights to Greenville are more costly in the afternoon, with an average ticket price of $426. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Manchester to Greenville flight route?

Fly from Manchester to Greenville for the best Manchester - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $388 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Manchester, New Hampshire for as low as $306 on momondo.

What cabin class options are available on Manchester to Greenville flights?

There is only 1 cabin class available to choose from on Manchester to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Manchester, New Hampshire to Greenville flight prices changed over time?

When to book flights from Manchester, New Hampshire to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Greenville (MHT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Greenville

Direct flights

None
There are no direct flights from Manchester, New Hampshire to Greenville. There are no popular flight routes from Manchester, New Hampshire to Greenville.
Search flight deals

  • How far is Manchester to Greenville by plane?

    A flight from Manchester to Greenville will travel around 811.9 mi. Flights usually cover this in 4h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Greenville Airport?

    Prices for flights from Manchester Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Greenville Airport?

  • How old do you have to be to fly from Manchester Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Manchester, New Hampshire to Greenville?

  • What is the most popular airline from Manchester, New Hampshire to Greenville?

Best airlines flying from Manchester, New Hampshire to Greenville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $227Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
SouthwestPriceFrom $236Free CancellationRating
8.0
4,244 reviews
Search Southwest flights
United AirlinesPriceFrom $303Free CancellationRating
7.4
9,013 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Manchester.

Can I find flights from Manchester to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Greenville?

Once all potential Manchester to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 12/17
Wed 12/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States