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Cheap flights from Manchester, New Hampshire to Greenville from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Greenville departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:44 am - 10:51 amMHT-GSP
5h 07m1 stop
American Airlines Logo
6:39 am - 11:07 amGSP-MHT
4h 28m1 stop
$345American Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
American Airlines Logo
4:40 pm - 9:39 pmMHT-GSP
4h 59m1 stop
American Airlines Logo
5:39 am - 11:11 amGSP-MHT
5h 32m1 stop
$350American Airlines
Find Deal
Sat, Dec 13 - Sun, Dec 21
Multiple Airlines Logo
7:36 pm - 3:06 pmMHT-GSP
19h 30m1 stop
Multiple Airlines Logo
8:03 pm - 6:56 pmGSP-MHT
22h 53m1 stop
$373Multiple Airlines
Find Deal
Wed, Nov 19 - Fri, Nov 21
Multiple Airlines Logo
11:17 am - 10:51 amMHT-GSP
23h 34m2 stops
Multiple Airlines Logo
8:03 pm - 6:56 pmGSP-MHT
22h 53m1 stop
$379Multiple Airlines
Find Deal
Thu, Nov 27 - Fri, Dec 5
Breeze Airways Logo
6:25 pm - 9:53 amMHT-GSP
15h 28m1 stop
Breeze Airways Logo
8:03 pm - 6:56 pmGSP-MHT
22h 53m1 stop
$381Breeze Airways
Find Deal
Sat, Nov 22 - Fri, Dec 5
Breeze Airways Logo
6:25 pm - 9:53 amMHT-GSP
15h 28m1 stop
Breeze Airways Logo
8:03 pm - 6:56 pmGSP-MHT
22h 53m1 stop
$404Breeze Airways
Find Deal
Wed, Nov 26 - Fri, Dec 5
Southwest Logo
8:40 am - 9:35 pmMHT-GSP
12h 55m2 stops
Southwest Logo
7:40 am - 12:20 pmGSP-MHT
4h 40m1 stop
$418Southwest
Find Deal
Mon, Nov 24 - Wed, Dec 3
Southwest Logo
5:45 am - 4:05 pmMHT-GSP
10h 20m2 stops
Southwest Logo
10:20 am - 11:00 pmGSP-MHT
12h 40m2 stops
$419Southwest
Find Deal
Tue, Dec 9 - Fri, Dec 12
United Airlines Logo
2:33 pm - 7:24 pmMHT-GSP
4h 51m1 stop
United Airlines Logo
6:00 am - 10:43 amGSP-MHT
4h 43m1 stop
$422United Airlines
Find Deal
Tue, Mar 3 - Thu, May 14
United Airlines Logo
2:33 pm - 11:59 pmMHT-GSP
9h 26m2 stops
United Airlines Logo
6:00 am - 10:43 amGSP-MHT
4h 43m1 stop
$427United Airlines
Find Deal
Tue, Mar 3 - Wed, May 20

United Airlines flights from Manchester, New Hampshire to Greenville

Our best United Airlines deals on Manchester, New Hampshire to Greenville flight tickets
United Airlines
Mar 3
MHT2:33 pmManchester
4h 51m
1 stop
GSP7:24 pmGreenville
May 14
GSP6:00 amGreenville
4h 43m
1 stop
MHT10:43 amManchester
$422
Find similar
United Airlines
Mar 3
MHT2:33 pmManchester
9h 26m
2 stops
GSP11:59 pmGreenville
May 20
GSP6:00 amGreenville
4h 43m
1 stop
MHT10:43 amManchester
$427
Find similar
United Airlines
Mar 3
MHT2:33 pmManchester
9h 26m
2 stops
GSP11:59 pmGreenville
May 19
GSP6:46 amGreenville
8h 17m
2 stops
MHT3:03 pmManchester
$432
Find similar

American Airlines flights from Manchester, New Hampshire to Greenville

Our best American Airlines deals on Manchester, New Hampshire to Greenville flight tickets
American Airlines
Dec 4
MHT5:44 amManchester
5h 07m
1 stop
GSP10:51 amGreenville
Dec 8
GSP6:39 amGreenville
4h 28m
1 stop
MHT11:07 amManchester
$345
Find similar
American Airlines
Dec 13
MHT4:40 pmManchester
4h 59m
1 stop
GSP9:39 pmGreenville
Dec 21
GSP5:39 amGreenville
5h 32m
1 stop
MHT11:11 amManchester
$350
Find similar
American Airlines
Dec 9
MHT3:52 pmManchester
4h 56m
1 stop
GSP8:48 pmGreenville
Dec 12
GSP6:39 amGreenville
4h 33m
1 stop
MHT11:12 amManchester
$352
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 12/4

5:44 am-10:51 am

1 stop5h 07m

Greenville

Mon 12/8

6:39 am-11:07 am

1 stop4h 28m

$345

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 12/13

4:40 pm-9:39 pm

1 stop4h 59m

Greenville

Sun 12/21

5:39 am-11:11 am

1 stop5h 32m

$350

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 11/19

7:36 pm-3:06 pm

1 stop19h 30m

Greenville

Fri 11/21

8:03 pm-6:56 pm

1 stop22h 53m

$373

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 11/27

11:17 am-10:51 am

2 stops23h 34m

Greenville

Fri 12/5

8:03 pm-6:56 pm

1 stop22h 53m

$379

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 11/22

6:25 pm-9:53 am

1 stop15h 28m

Greenville

Fri 12/5

8:03 pm-6:56 pm

1 stop22h 53m

$381

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 11/26

6:25 pm-9:53 am

1 stop15h 28m

Greenville

Fri 12/5

8:03 pm-6:56 pm

1 stop22h 53m

$404

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Mon 11/24

8:40 am-9:35 pm

2 stops12h 55m

Greenville

Wed 12/3

7:40 am-12:20 pm

1 stop4h 40m

$418

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 12/9

5:45 am-4:05 pm

2 stops10h 20m

Greenville

Fri 12/12

10:20 am-11:00 pm

2 stops12h 40m

$419

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 3/3

2:33 pm-7:24 pm

1 stop4h 51m

Greenville

Thu 5/14

6:00 am-10:43 am

1 stop4h 43m

$422

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 3/3

2:33 pm-11:59 pm

2 stops9h 26m

Greenville

Wed 5/20

6:00 am-10:43 am

1 stop4h 43m

$427

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Manchester, New Hampshire averaging around $329.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Manchester, New Hampshire. The lowest ticket price found for a Tuesday departure recently was $322. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $396. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Manchester, New Hampshire to Greenville during this time can be as low as $326. Flights to Greenville are more costly in the afternoon, with an average ticket price of $426. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Manchester to Greenville flight route?

Fly from Manchester to Greenville for the best Manchester - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $374 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Manchester, New Hampshire for as low as $286 on momondo.

What cabin class options are available on Manchester to Greenville flights?

There is only 1 cabin class available to choose from on Manchester to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Manchester, New Hampshire to Greenville flight prices changed over time?

When to book flights from Manchester, New Hampshire to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Greenville (MHT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Greenville

Direct flights

None
There are no direct flights from Manchester, New Hampshire to Greenville. There are no popular flight routes from Manchester, New Hampshire to Greenville.
Search flight deals

  • How far is Manchester to Greenville by plane?

    A flight from Manchester to Greenville will travel around 811.9 mi. Flights usually cover this in 4h 03m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Greenville Airport?

    Prices for flights from Manchester Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Greenville Airport?

  • How old do you have to be to fly from Manchester Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Manchester, New Hampshire to Greenville?

  • What is the most popular airline from Manchester, New Hampshire to Greenville?

Best airlines flying from Manchester, New Hampshire to Greenville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $227Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
SouthwestPriceFrom $236Free CancellationRating
8.0
4,241 reviews
Search Southwest flights
United AirlinesPriceFrom $303Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Manchester.

Can I find flights from Manchester to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Greenville?

Once all potential Manchester to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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