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Cheap flights from Manchester, New Hampshire to Greenville from $203

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Greenville departing on 11/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Manchester, New Hampshire to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:09 pm - 4:19 pmMHT-GSP
22h 10m1 stop
Multiple Airlines Logo
9:47 pm - 2:33 pmGSP-MHT
16h 46m2 stops
$349Multiple Airlines
Find Deal
Wed, Feb 4 - Sun, Feb 8
American Airlines Logo
6:00 am - 10:13 amMHT-GSP
4h 13m1 stop
American Airlines Logo
5:39 am - 11:11 amGSP-MHT
5h 32m1 stop
$350American Airlines
Find Deal
Wed, Dec 31 - Sun, Jan 4
Southwest Logo
5:55 am - 10:40 amMHT-GSP
4h 45m1 stop
Southwest Logo
6:15 pm - 10:05 pmGSP-MHT
3h 50m1 stop
$352Southwest
Find Deal
Wed, Feb 4 - Sun, Feb 8
American Airlines Logo
5:45 am - 10:07 amMHT-GSP
4h 22m1 stop
American Airlines Logo
6:26 pm - 10:56 pmGSP-MHT
4h 30m1 stop
$356American Airlines
Find Deal
Sat, Dec 13 - Sun, Dec 21
United Airlines Logo
2:32 pm - 7:10 pmMHT-GSP
4h 38m1 stop
United Airlines Logo
2:52 pm - 6:49 pmGSP-MHT
3h 57m1 stop
$362United Airlines
Find Deal
Wed, Dec 3 - Fri, Dec 5
American Airlines Logo
6:42 am - 1:17 pmMHT-GSP
6h 35m1 stop
American Airlines Logo
7:21 am - 11:35 amGSP-MHT
4h 14m1 stop
$364American Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
United Airlines Logo
2:32 pm - 11:59 pmMHT-GSP
9h 27m2 stops
United Airlines Logo
2:52 pm - 6:49 pmGSP-MHT
3h 57m1 stop
$367United Airlines
Find Deal
Wed, Dec 3 - Fri, Dec 5
American Airlines Logo
5:30 am - 1:17 pmMHT-GSP
7h 47m2 stops
American Airlines Logo
11:00 am - 3:38 pmGSP-MHT
4h 38m1 stop
$369American Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
United Airlines Logo
2:32 pm - 11:59 pmMHT-GSP
9h 27m2 stops
United Airlines Logo
9:05 am - 6:49 pmGSP-MHT
9h 44m2 stops
$372United Airlines
Find Deal
Wed, Dec 3 - Fri, Dec 5
American Airlines Logo
11:42 am - 8:48 pmMHT-GSP
9h 06m2 stops
American Airlines Logo
3:39 pm - 11:50 pmGSP-MHT
8h 11m2 stops
$374American Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25

American Airlines flights from Manchester, New Hampshire to Greenville

Our best American Airlines deals on Manchester, New Hampshire to Greenville flight tickets
American Airlines
Dec 31
MHT6:00 amManchester
4h 13m
1 stop
GSP10:13 amGreenville
Jan 4
GSP5:39 amGreenville
5h 32m
1 stop
MHT11:11 amManchester
$350
Find similar
American Airlines
Dec 13
MHT5:45 amManchester
4h 22m
1 stop
GSP10:07 amGreenville
Dec 21
GSP6:26 pmGreenville
4h 30m
1 stop
MHT10:56 pmManchester
$356
Find similar
American Airlines
Jan 22
MHT6:42 amManchester
6h 35m
1 stop
GSP1:17 pmGreenville
Jan 25
GSP7:21 amGreenville
4h 14m
1 stop
MHT11:35 amManchester
$364
Find similar

United Airlines flights from Manchester, New Hampshire to Greenville

Our best United Airlines deals on Manchester, New Hampshire to Greenville flight tickets
United Airlines
Feb 4
MHT2:17 pmManchester
5h 12m
1 stop
GSP7:29 pmGreenville
Feb 9
GSP2:55 pmGreenville
3h 56m
1 stop
MHT6:51 pmManchester
$329
Find similar
United Airlines
Feb 4
MHT2:17 pmManchester
9h 31m
2 stops
GSP11:48 pmGreenville
Feb 9
GSP2:55 pmGreenville
3h 56m
1 stop
MHT6:51 pmManchester
$334
Find similar
United Airlines
Feb 4
MHT2:17 pmManchester
9h 31m
2 stops
GSP11:48 pmGreenville
Feb 9
GSP10:51 amGreenville
8h 00m
2 stops
MHT6:51 pmManchester
$339
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 2/4

6:09 pm-4:19 pm

1 stop22h 10m

Greenville

Sun 2/8

9:47 pm-2:33 pm

2 stops16h 46m

$349

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 12/31

6:00 am-10:13 am

1 stop4h 13m

Greenville

Sun 1/4

5:39 am-11:11 am

1 stop5h 32m

$350

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 2/4

5:55 am-10:40 am

1 stop4h 45m

Greenville

Sun 2/8

6:15 pm-10:05 pm

1 stop3h 50m

$352

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 12/13

5:45 am-10:07 am

1 stop4h 22m

Greenville

Sun 12/21

6:26 pm-10:56 pm

1 stop4h 30m

$356

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 12/3

2:32 pm-7:10 pm

1 stop4h 38m

Greenville

Fri 12/5

2:52 pm-6:49 pm

1 stop3h 57m

$362

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

6:42 am-1:17 pm

1 stop6h 35m

Greenville

Sun 1/25

7:21 am-11:35 am

1 stop4h 14m

$364

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 12/3

2:32 pm-11:59 pm

2 stops9h 27m

Greenville

Fri 12/5

2:52 pm-6:49 pm

1 stop3h 57m

$367

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

5:30 am-1:17 pm

2 stops7h 47m

Greenville

Sun 1/25

11:00 am-3:38 pm

1 stop4h 38m

$369

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 12/3

2:32 pm-11:59 pm

2 stops9h 27m

Greenville

Fri 12/5

9:05 am-6:49 pm

2 stops9h 44m

$372

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

11:42 am-8:48 pm

2 stops9h 06m

Greenville

Sun 1/25

3:39 pm-11:50 pm

2 stops8h 11m

$374

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Manchester, New Hampshire averaging around $329.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Manchester, New Hampshire. The lowest ticket price found for a Tuesday departure recently was $322. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $396. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Manchester, New Hampshire to Greenville during this time can be as low as $326. Flights to Greenville are more costly in the afternoon, with an average ticket price of $426. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Manchester to Greenville flight route?

Fly from Manchester to Greenville for the best Manchester - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $388 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Manchester, New Hampshire for as low as $306 on momondo.

What cabin class options are available on Manchester to Greenville flights?

There is only 1 cabin class available to choose from on Manchester to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Manchester, New Hampshire to Greenville flight prices changed over time?

When to book flights from Manchester, New Hampshire to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Greenville (MHT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Greenville

Direct flights

None
There are no direct flights from Manchester, New Hampshire to Greenville. There are no popular flight routes from Manchester, New Hampshire to Greenville.
Search flight deals

  • How far is Manchester to Greenville by plane?

    A flight from Manchester to Greenville will travel around 811.9 mi. Flights usually cover this in 4h 00m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Greenville Airport?

    Prices for flights from Manchester Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Greenville Airport?

  • How old do you have to be to fly from Manchester Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Manchester, New Hampshire to Greenville?

  • What is the most popular airline from Manchester, New Hampshire to Greenville?

Best airlines flying from Manchester, New Hampshire to Greenville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $227Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
SouthwestPriceFrom $236Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
United AirlinesPriceFrom $303Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Manchester.

Can I find flights from Manchester to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Greenville?

Once all potential Manchester to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Greenville trip

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