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Cheap flights from Manchester, New Hampshire to Greenville from $141

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Greenville departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Manchester, New Hampshire to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:15 am - 10:40 am
MHT
-
GSP
5h 25m1 stop
American Airlines Logo
6:00 am - 11:16 am
GSP
-
MHT
5h 16m1 stop
$309American Airlines
Thu, Feb 26 - Sat, Feb 28
American Airlines Logo
11:42 am - 5:56 pm
MHT
-
GSP
6h 14m1 stop
American Airlines Logo
11:00 am - 3:38 pm
GSP
-
MHT
4h 38m1 stop
$348American Airlines
Thu, Jan 22 - Sun, Jan 25
American Airlines Logo
11:42 am - 5:56 pm
MHT
-
GSP
6h 14m1 stop
American Airlines Logo
8:09 am - 3:38 pm
GSP
-
MHT
7h 29m2 stops
$353American Airlines
Thu, Jan 22 - Sun, Jan 25
American Airlines Logo
4:06 pm - 11:26 pm
MHT
-
GSP
7h 20m2 stops
American Airlines Logo
3:39 pm - 11:50 pm
GSP
-
MHT
8h 11m2 stops
$358American Airlines
Thu, Jan 22 - Sun, Jan 25
American Airlines Logo
5:30 am - 1:17 pm
MHT
-
GSP
7h 47m2 stops
American Airlines Logo
6:00 am - 3:38 pm
GSP
-
MHT
9h 38m2 stops
$377American Airlines
Thu, Jan 22 - Sun, Jan 25
United Airlines Logo
2:33 pm - 11:59 pm
MHT
-
GSP
9h 26m2 stops
United Airlines Logo
2:51 pm - 6:53 pm
GSP
-
MHT
4h 02m1 stop
$380United Airlines
Tue, Feb 17 - Wed, Feb 18
United Airlines Logo
2:33 pm - 11:59 pm
MHT
-
GSP
9h 26m2 stops
United Airlines Logo
10:40 am - 6:53 pm
GSP
-
MHT
8h 13m2 stops
$385United Airlines
Tue, Feb 17 - Wed, Feb 18
Southwest Logo
2:45 pm - 8:30 pm
MHT
-
GSP
5h 45m1 stop
Southwest Logo
8:00 am - 12:30 pm
GSP
-
MHT
4h 30m1 stop
$387Southwest
Tue, Mar 24 - Thu, Mar 26
Southwest Logo
1:35 pm - 10:40 pm
MHT
-
GSP
9h 05m2 stops
Southwest Logo
8:00 am - 12:30 pm
GSP
-
MHT
4h 30m1 stop
$392Southwest
Tue, Mar 24 - Thu, Mar 26
Southwest Logo
7:25 am - 5:45 pm
MHT
-
GSP
10h 20m2 stops
Southwest Logo
12:25 pm - 10:05 pm
GSP
-
MHT
9h 40m2 stops
$397Southwest
Tue, Mar 24 - Thu, Mar 26

Southwest flights from Manchester, New Hampshire to Greenville

Our best Southwest deals on Manchester, New Hampshire to Greenville flight tickets
Southwest
Mar 24
MHT2:45 pmManchester
5h 45m
1 stop
GSP8:30 pmGreenville
Mar 26
GSP8:00 amGreenville
4h 30m
1 stop
MHT12:30 pmManchester
$387
Find similar
Southwest
Mar 24
MHT1:35 pmManchester
9h 05m
2 stops
GSP10:40 pmGreenville
Mar 26
GSP8:00 amGreenville
4h 30m
1 stop
MHT12:30 pmManchester
$392
Find similar
Southwest
Mar 24
MHT7:25 amManchester
10h 20m
2 stops
GSP5:45 pmGreenville
Mar 26
GSP12:25 pmGreenville
9h 40m
2 stops
MHT10:05 pmManchester
$397
Find similar

American Airlines flights from Manchester, New Hampshire to Greenville

Our best American Airlines deals on Manchester, New Hampshire to Greenville flight tickets
American Airlines
Feb 26
MHT5:15 amManchester
5h 25m
1 stop
GSP10:40 amGreenville
Feb 28
GSP6:00 amGreenville
5h 16m
1 stop
MHT11:16 amManchester
$309
Find similar
American Airlines
Jan 22
MHT5:30 amManchester
5h 00m
1 stop
GSP10:30 amGreenville
Jan 25
GSP11:00 amGreenville
4h 38m
1 stop
MHT3:38 pmManchester
$348
Find similar
American Airlines
Jan 22
MHT11:42 amManchester
6h 14m
1 stop
GSP5:56 pmGreenville
Jan 25
GSP8:09 amGreenville
7h 29m
2 stops
MHT3:38 pmManchester
$353
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 2/26

5:15 am-10:40 am

1 stop5h 25m

Greenville

Sat 2/28

6:00 am-11:16 am

1 stop5h 16m

$309

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

11:42 am-5:56 pm

1 stop6h 14m

Greenville

Sun 1/25

11:00 am-3:38 pm

1 stop4h 38m

$348

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

11:42 am-5:56 pm

1 stop6h 14m

Greenville

Sun 1/25

8:09 am-3:38 pm

2 stops7h 29m

$353

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

4:06 pm-11:26 pm

2 stops7h 20m

Greenville

Sun 1/25

3:39 pm-11:50 pm

2 stops8h 11m

$358

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 1/22

5:30 am-1:17 pm

2 stops7h 47m

Greenville

Sun 1/25

6:00 am-3:38 pm

2 stops9h 38m

$377

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 2/17

2:33 pm-11:59 pm

2 stops9h 26m

Greenville

Wed 2/18

2:51 pm-6:53 pm

1 stop4h 02m

$380

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 2/17

2:33 pm-11:59 pm

2 stops9h 26m

Greenville

Wed 2/18

10:40 am-6:53 pm

2 stops8h 13m

$385

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 3/24

2:45 pm-8:30 pm

1 stop5h 45m

Greenville

Thu 3/26

8:00 am-12:30 pm

1 stop4h 30m

$387

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 3/24

1:35 pm-10:40 pm

2 stops9h 05m

Greenville

Thu 3/26

8:00 am-12:30 pm

1 stop4h 30m

$392

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 3/24

7:25 am-5:45 pm

2 stops10h 20m

Greenville

Thu 3/26

12:25 pm-10:05 pm

2 stops9h 40m

$397

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Manchester, New Hampshire averaging around $329.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Manchester, New Hampshire. The lowest ticket price found for a Tuesday departure recently was $322. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $396. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Manchester, New Hampshire to Greenville during this time can be as low as $326. Flights to Greenville are more costly in the afternoon, with an average ticket price of $426. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $385 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Manchester, New Hampshire for as low as $305 on momondo.

How have Manchester, New Hampshire to Greenville flight prices changed over time?

When to book flights from Manchester, New Hampshire to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Greenville (MHT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Greenville

Fastest flight time

4h 00m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Greenville takes 4h 00m
There are no direct flights from Manchester, New Hampshire to Greenville. There are no popular flight routes from Manchester, New Hampshire to Greenville.
Search flight deals

  • How far is Manchester to Greenville by plane?

    A flight from Manchester to Greenville will travel around 811.9 mi. Flights usually cover this in 4h 00m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Greenville Airport?

    Prices for flights from Manchester Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Greenville Airport?

  • How old do you have to be to fly from Manchester Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Manchester, New Hampshire to Greenville?

  • What is the most popular airline from Manchester, New Hampshire to Greenville?

Best airlines flying from Manchester, New Hampshire to Greenville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Greenville with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $220Free CancellationRating
8.0
4,253 reviews
Search Southwest flights
American AirlinesPriceFrom $227Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $303Free CancellationRating
7.4
9,105 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Manchester.

Can I find flights from Manchester to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Greenville?

Once all potential Manchester to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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