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Cheap flights from Manchester, New Hampshire to Greenville from $163

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Greenville departing on 9/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Manchester, New Hampshire to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:10 pm - 9:42 pmMHT  Manchester-GSP Greenville
4h 32m1 stop Charlotte Douglas
American Airlines Logo
4:49 pm - 11:58 pmGSP  Greenville-MHT Manchester
7h 09m1 stop Washington, D.C. Reagan-National
$326American Airlines
Sat, Sep 5 - Wed, Sep 9
United Airlines Logo
2:46 pm - 7:05 pmMHT  Manchester-GSP Greenville
4h 19m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
10:33 am - 7:00 pmGSP  Greenville-MHT Manchester
8h 27m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$331United Airlines
Sat, Sep 5 - Wed, Sep 9
Breeze Airways Logo
9:55 am - 9:57 amMHT  Manchester-GSP Greenville
24h 02m1 stop Fort Myers SW Florida Intl
Breeze Airways Logo
8:32 pm - 11:38 amGSP  Greenville-MHT Manchester
15h 06m2 stops Orlando Charleston
$334Breeze Airways
Sat, Sep 26 - Fri, Oct 2
American Airlines Logo
8:15 am - 2:41 pmMHT  Manchester-GSP Greenville
6h 26m1 stop Philadelphia
American Airlines Logo
9:27 am - 4:42 pmGSP  Greenville-MHT Manchester
7h 15m1 stop Charlotte Douglas
$338American Airlines
Mon, Aug 31 - Sun, Sep 6
American Airlines Logo
6:00 am - 12:30 pmMHT  Manchester-GSP Greenville
6h 30m1 stop Philadelphia
American Airlines Logo
6:00 am - 10:55 amGSP  Greenville-MHT Manchester
4h 55m1 stop Charlotte Douglas
$338American Airlines
Sat, Sep 5 - Mon, Sep 7
United Airlines Logo
9:25 am - 2:19 pmMHT  Manchester-GSP Greenville
4h 54m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
7:00 am - 2:08 pmGSP  Greenville-MHT Manchester
7h 08m2 stops Newark Washington, D.C. Dulles Intl
$343United Airlines
Mon, Aug 31 - Sun, Sep 6
United Airlines Logo
9:25 am - 2:19 pmMHT  Manchester-GSP Greenville
4h 54m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
7:00 am - 2:08 pmGSP  Greenville-MHT Manchester
7h 08m2 stops Newark Washington, D.C. Dulles Intl
$343United Airlines
Mon, Aug 31 - Sun, Sep 6
Southwest Logo
5:45 am - 10:45 amMHT  Manchester-GSP Greenville
5h 00m1 stop Baltimore/Washington
Southwest Logo
1:25 pm - 10:40 pmGSP  Greenville-MHT Manchester
9h 15m1 stop Baltimore/Washington
$356Southwest
Sat, Oct 10 - Tue, Oct 13
Southwest Logo
7:45 am - 7:30 pmMHT  Manchester-GSP Greenville
11h 45m2 stops Chicago Midway Baltimore/Washington
Southwest Logo
1:20 pm - 9:55 pmGSP  Greenville-MHT Manchester
8h 35m1 stop Baltimore/Washington
$362Southwest
Wed, Sep 16 - Wed, Sep 23
Breeze Airways Logo
9:55 am - 9:57 amMHT  Manchester-GSP Greenville
24h 02m1 stop Fort Myers SW Florida Intl
Breeze Airways Logo
10:07 am - 2:34 pmGSP  Greenville-MHT Manchester
28h 27m2 stops Tampa Myrtle Beach Intl
$383Breeze Airways
Sat, Sep 26 - Thu, Oct 1

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American Airlines flights from Manchester, New Hampshire to Greenville

Our best American Airlines deals on Manchester, New Hampshire to Greenville flight tickets
American Airlines
Sep 5
MHT5:10 pmManchester
4h 32m
1 stop
GSP9:42 pmGreenville
Sep 9
GSP4:49 pmGreenville
7h 09m
1 stop
MHT11:58 pmManchester
$326
American Airlines
Aug 31
MHT6:00 amManchester
4h 24m
1 stop
GSP10:24 amGreenville
Sep 6
GSP6:08 pmGreenville
4h 44m
1 stop
MHT10:52 pmManchester
$338
American Airlines
Sep 3
MHT2:42 pmManchester
5h 03m
1 stop
GSP7:45 pmGreenville
Sep 7
GSP6:00 amGreenville
4h 55m
1 stop
MHT10:55 amManchester
$351

Southwest flights from Manchester, New Hampshire to Greenville

Our best Southwest deals on Manchester, New Hampshire to Greenville flight tickets
Southwest
Sep 16
MHT7:45 amManchester
11h 45m
2 stops
GSP7:30 pmGreenville
Sep 23
GSP1:20 pmGreenville
8h 35m
1 stop
MHT9:55 pmManchester
$362
Southwest
Sep 17
MHT3:30 pmManchester
4h 50m
1 stop
GSP8:20 pmGreenville
Sep 22
GSP1:20 pmGreenville
8h 35m
1 stop
MHT9:55 pmManchester
$373
Southwest
Sep 22
MHT10:05 amManchester
10h 55m
2 stops
GSP9:00 pmGreenville
Sep 25
GSP1:05 pmGreenville
9h 25m
2 stops
MHT10:30 pmManchester
$378

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Manchester, New Hampshire to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 9/5

5:10 pm-9:42 pm

1 stop4h 32m

Greenville

Wed 9/9

4:49 pm-11:58 pm

1 stop7h 09m

$326

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 9/5

2:46 pm-7:05 pm

1 stop4h 19m

Greenville

Wed 9/9

10:33 am-7:00 pm

2 stops8h 27m

$331

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 9/26

9:55 am-9:57 am

1 stop24h 02m

Greenville

Fri 10/2

8:32 pm-11:38 am

2 stops15h 06m

$334

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Mon 8/31

8:15 am-2:41 pm

1 stop6h 26m

Greenville

Sun 9/6

9:27 am-4:42 pm

1 stop7h 15m

$338
Quickest round-trip

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 9/5

6:00 am-12:30 pm

1 stop6h 30m

Greenville

Mon 9/7

6:00 am-10:55 am

1 stop4h 55m

$338

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Mon 8/31

9:25 am-2:19 pm

1 stop4h 54m

Greenville

Sun 9/6

7:00 am-2:08 pm

2 stops7h 08m

$343

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Mon 8/31

9:25 am-2:19 pm

1 stop4h 54m

Greenville

Sun 9/6

7:00 am-2:08 pm

2 stops7h 08m

$343

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 10/10

5:45 am-10:45 am

1 stop5h 00m

Greenville

Tue 10/13

1:25 pm-10:40 pm

1 stop9h 15m

$356

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Wed 9/16

7:45 am-7:30 pm

2 stops11h 45m

Greenville

Wed 9/23

1:20 pm-9:55 pm

1 stop8h 35m

$362

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 9/26

9:55 am-9:57 am

1 stop24h 02m

Greenville

Thu 10/1

10:07 am-2:34 pm

2 stops28h 27m

$383

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester, New Hampshire and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $361 to $565.
The lowest price recently found on this route was $326.

What is the cheapest month to fly to Greenville?

The month of February is another great option to travel to Greenville, with average flight prices from Manchester, New Hampshire averaging around $390.

How far in advance should I book a flight from Manchester, New Hampshire to Greenville?

You are more likely to see cheaper flights to Greenville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $439 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Manchester, New Hampshire for as low as $339 on momondo.

How have Manchester, New Hampshire to Greenville flight prices changed over time?

When to book flights from Manchester, New Hampshire to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Greenville (MHT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Greenville

Fastest flight time

4h 05m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Greenville takes 4h 05m
There are no direct flights from Manchester, New Hampshire to Greenville. There are no popular flight routes from Manchester, New Hampshire to Greenville.
Search flight deals

Frequently asked questions about flying from Manchester, New Hampshire to Greenville

  • How far is Manchester to Greenville by plane?

    A flight from Manchester to Greenville will travel around 811.9 mi. Flights usually cover this in 4h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Greenville Airport?

    Prices for flights from Manchester Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Greenville Airport?

  • How old do you have to be to fly from Manchester Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Manchester, New Hampshire to Greenville?

Best airlines flying from Manchester, New Hampshire to Greenville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $274Free CancellationRating
7.1
11,877 reviews
Search American Airlines flights
SouthwestPriceFrom $286Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
United AirlinesPriceFrom $386Free CancellationRating
7.4
10,077 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Manchester.

Can I find flights from Manchester to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Greenville?

Once all potential Manchester to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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