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Cheap flights from Manchester, New Hampshire to Greenville from $194

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Greenville departing on 11/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to Greenville

Cheap round-trip flights

Multiple Airlines Logo
7:36 pm - 2:54 pmMHT-GSP
19h 18m1 stop
Multiple Airlines Logo
8:03 pm - 6:56 pmGSP-MHT
22h 53m1 stop
$288Multiple Airlines
Find Deal
Sat, Oct 4 - Fri, Oct 10
Southwest Logo
5:45 am - 10:00 amMHT-GSP
4h 15m1 stop
Southwest Logo
4:45 pm - 10:10 pmGSP-MHT
5h 25m1 stop
$297Southwest
Find Deal
Tue, Nov 11 - Tue, Nov 18
Southwest Logo
5:45 am - 10:00 amMHT-GSP
4h 15m1 stop
Southwest Logo
10:35 am - 9:05 pmGSP-MHT
10h 30m2 stops
$302Southwest
Find Deal
Tue, Nov 11 - Tue, Nov 18
Southwest Logo
5:25 am - 9:55 amMHT-GSP
4h 30m1 stop
Southwest Logo
4:45 pm - 10:10 pmGSP-MHT
5h 25m1 stop
$305Southwest
Find Deal
Mon, Oct 27 - Wed, Nov 5
Breeze Airways Logo
2:24 pm - 9:53 amMHT-GSP
19h 29m1 stop
Breeze Airways Logo
8:03 pm - 6:56 pmGSP-MHT
22h 53m1 stop
$309Breeze Airways
Find Deal
Sat, Sep 27 - Fri, Oct 3
United Airlines Logo
2:17 pm - 11:48 pmMHT-GSP
9h 31m2 stops
United Airlines Logo
10:51 am - 6:51 pmGSP-MHT
8h 00m2 stops
$331United Airlines
Find Deal
Fri, Jan 9 - Wed, Jan 14
American Airlines Logo
6:00 am - 10:40 amMHT-GSP
4h 40m1 stop
American Airlines Logo
7:11 pm - 11:51 pmGSP-MHT
4h 40m1 stop
$340American Airlines
Find Deal
Wed, Oct 22 - Mon, Oct 27
American Airlines Logo
5:20 pm - 10:31 pmMHT-GSP
5h 11m1 stop
American Airlines Logo
6:00 am - 11:03 amGSP-MHT
5h 03m1 stop
$350American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
Breeze Airways Logo
6:25 pm - 9:53 amMHT-GSP
15h 28m1 stop
Breeze Airways Logo
8:03 pm - 6:56 pmGSP-MHT
22h 53m1 stop
$365Breeze Airways
Find Deal
Wed, Oct 1 - Fri, Oct 3
United Airlines Logo
9:40 am - 2:11 pmMHT-GSP
4h 31m1 stop
United Airlines Logo
10:05 am - 3:02 pmGSP-MHT
4h 57m1 stop
$367United Airlines
Find Deal
Wed, Oct 8 - Tue, Oct 14

Southwest flights from Manchester, New Hampshire to Greenville

Our best Southwest deals on Manchester, New Hampshire to Greenville flight tickets
Southwest
Nov 11
MHT5:45 amManchester
4h 15m
1 stop
GSP10:00 amGreenville
Nov 18
GSP4:45 pmGreenville
5h 25m
1 stop
MHT10:10 pmManchester
$297
Find similar
Southwest
Nov 11
MHT5:45 amManchester
4h 15m
1 stop
GSP10:00 amGreenville
Nov 18
GSP10:35 amGreenville
10h 30m
2 stops
MHT9:05 pmManchester
$302
Find similar
Southwest
Oct 27
MHT5:25 amManchester
4h 30m
1 stop
GSP9:55 amGreenville
Nov 5
GSP4:45 pmGreenville
5h 25m
1 stop
MHT10:10 pmManchester
$305
Find similar

American Airlines flights from Manchester, New Hampshire to Greenville

Our best American Airlines deals on Manchester, New Hampshire to Greenville flight tickets
American Airlines
Oct 22
MHT6:00 amManchester
4h 40m
1 stop
GSP10:40 amGreenville
Oct 27
GSP7:11 pmGreenville
4h 40m
1 stop
MHT11:51 pmManchester
$340
Find similar
American Airlines
Nov 13
MHT5:20 pmManchester
5h 11m
1 stop
GSP10:31 pmGreenville
Nov 16
GSP6:00 amGreenville
5h 03m
1 stop
MHT11:03 amManchester
$350
Find similar
American Airlines
Nov 14
MHT12:09 pmManchester
10h 22m
1 stop
GSP10:31 pmGreenville
Nov 17
GSP6:19 pmGreenville
4h 38m
1 stop
MHT10:57 pmManchester
$364
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 10/4

7:36 pm-2:54 pm

1 stop19h 18m

Greenville

Fri 10/10

8:03 pm-6:56 pm

1 stop22h 53m

$288

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 11/11

5:45 am-10:00 am

1 stop4h 15m

Greenville

Tue 11/18

4:45 pm-10:10 pm

1 stop5h 25m

$297

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Tue 11/11

5:45 am-10:00 am

1 stop4h 15m

Greenville

Tue 11/18

10:35 am-9:05 pm

2 stops10h 30m

$302

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Mon 10/27

5:25 am-9:55 am

1 stop4h 30m

Greenville

Wed 11/5

4:45 pm-10:10 pm

1 stop5h 25m

$305

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sat 9/27

2:24 pm-9:53 am

1 stop19h 29m

Greenville

Fri 10/3

8:03 pm-6:56 pm

1 stop22h 53m

$309

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Fri 1/9

2:17 pm-11:48 pm

2 stops9h 31m

Greenville

Wed 1/14

10:51 am-6:51 pm

2 stops8h 00m

$331

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 10/22

6:00 am-10:40 am

1 stop4h 40m

Greenville

Mon 10/27

7:11 pm-11:51 pm

1 stop4h 40m

$340

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Thu 11/13

5:20 pm-10:31 pm

1 stop5h 11m

Greenville

Sun 11/16

6:00 am-11:03 am

1 stop5h 03m

$350

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 10/1

6:25 pm-9:53 am

1 stop15h 28m

Greenville

Fri 10/3

8:03 pm-6:56 pm

1 stop22h 53m

$365

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Wed 10/8

9:40 am-2:11 pm

1 stop4h 31m

Greenville

Tue 10/14

10:05 am-3:02 pm

1 stop4h 57m

$367

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Manchester, New Hampshire averaging around $274.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Manchester, New Hampshire. The lowest ticket price found for a Tuesday departure recently was $322. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $396. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Manchester, New Hampshire to Greenville during this time can be as low as $326. Flights to Greenville are more costly in the afternoon, with an average ticket price of $426. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Manchester to Greenville flight route?

Fly from Manchester to Greenville for the best Manchester - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $354 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Manchester, New Hampshire for as low as $296 on momondo.

What cabin class options are available on Manchester to Greenville flights?

There is only 1 cabin class available to choose from on Manchester to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Manchester, New Hampshire to Greenville flight prices changed over time?

When to book flights from Manchester, New Hampshire to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Greenville (MHT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Greenville

Direct flights

None
There are no direct flights from Manchester, New Hampshire to Greenville. There are no popular flight routes from Manchester, New Hampshire to Greenville.
Search flight deals

  • How far is Manchester to Greenville by plane?

    A flight from Manchester to Greenville will travel around 811.9 mi. Flights usually cover this in 3h 55m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Manchester Airport to Greenville Airport?

    Prices for flights from Manchester Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to Greenville Airport?

  • How old do you have to be to fly from Manchester Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Manchester, New Hampshire to Greenville?

  • What is the most popular airline from Manchester, New Hampshire to Greenville?

Best airlines flying from Manchester, New Hampshire to Greenville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Greenville with momondo
Airline
Rating
Free Cancellation
Price
Avelo AirlinesPriceFrom $95Free CancellationRating
7.5
78 reviews
Search Avelo Airlines flights
American AirlinesPriceFrom $227Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $236Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
United AirlinesPriceFrom $303Free CancellationRating
7.4
8,924 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from Manchester.

Can I find flights from Manchester to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Greenville?

Once all potential Manchester to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Greenville trip

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