Cheap flights from Los Angeles to St. Louis from $167

In general, January is the cheapest month to fly from Los Angeles to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $397. The month of November is another great option to travel to St. Louis, with average flight prices from Los Angeles averaging around $422.

The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $425. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $596. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Los Angeles in the evening is the least expensive time of day to depart. momondo users have found prices as low as $437 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $579 per ticket.

Fly from Los Angeles to Lambert-St Louis for the best Los Angeles - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Los Angeles when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $463 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Los Angeles for as low as $414 on momondo.

There are 4 cabin classes available to choose from on Los Angeles to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest is the most popular carrier operating from Los Angeles to Lambert-St Louis

Southwest, American Airlines and Frontier are the top three most popular airlines that fly to St. Louis from Los Angeles according to our data. Southwest is the first choice among our users, with 59% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 7 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

Denver (DEN) was the most common stop: 86% of momondo users choosing 1-stop flights on this route connected there.

Flights via Las Vegas (LAS) offer the lowest average round-trip price of $260.

Flights connecting via Denver (DEN) have the shortest average one-way travel time: 8h 15m.

Denver (DEN) has the shortest average layover time for this route: 2h 42m.

As of October 2026, there are 8 flights per day flying from Los Angeles to St. Louis. The most common time of day flights depart is 6:00PM, with 73% of flights taking off in the evening.

As of October 2026, 58 flights take off from Los Angeles and land in St. Louis each week. The most common flight departure day for this route is Fri, with 22% of weekly flights taking off on this day.