Cheap flights from Los Angeles to St. Louis from $159

In general, October is the cheapest month to fly from Los Angeles to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $340. The month of September is another great option to travel to St. Louis, with average flight prices from Los Angeles averaging around $367.

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $400. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $545. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Los Angeles in the evening is the least expensive time of day to depart. momondo users have found prices as low as $331 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $551 per ticket.

Fly from Los Angeles to Lambert-St Louis for the best Los Angeles - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Los Angeles when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $419 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Los Angeles for as low as $353 on momondo.

There are 4 cabin classes available to choose from on Los Angeles to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Los Angeles to St. Louis.

As of June 2026, prices for Los Angeles to St. Louis flights are approximately 70% more expensive when compared to flights at the same time last year.

Frontier is the most popular carrier operating from Los Angeles to Lambert-St Louis

Southwest, American Airlines and Frontier are the top three most popular airlines that fly to St. Louis from Los Angeles according to our data. Southwest is the first choice among our users, with 56% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 7 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

Denver (DEN) was the most common stop: 86% of momondo users choosing 1-stop flights on this route connected there.

Flights via Las Vegas (LAS) offer the lowest average round-trip price of $260.

Flights connecting via Denver (DEN) have the shortest average one-way travel time: 8h 15m.

Denver (DEN) has the shortest average layover time for this route: 2h 42m.

As of June 2026, there are 9 flights per day flying from Los Angeles to St. Louis. The most common time of day flights depart is 6:00PM, with 84% of flights taking off in the evening.

As of June 2026, 67 flights take off from Los Angeles and land in St. Louis each week. The most common flight departure day for this route is Mon, with 15% of weekly flights taking off on this day.