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Cheap flights from Knoxville to Milwaukee from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Milwaukee departing on 9/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Milwaukee

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:00 am - 10:00 am
TYS
-
MKE
4h 00m
1 stop
United Airlines Logo
6:47 pm - 12:23 am
MKE
-
TYS
4h 36m
1 stop
$274United Airlines
Sat, Sep 5 - Tue, Sep 8
United Airlines Logo
7:00 am - 10:00 am
TYS
-
MKE
4h 00m
1 stop
United Airlines Logo
1:19 pm - 8:53 pm
MKE
-
TYS
6h 34m
1 stop
$279United Airlines
Mon, Aug 17 - Mon, Aug 24
Southwest Logo
7:00 am - 9:50 am
TYS
-
MKE
3h 50m
1 stop
Southwest Logo
10:30 am - 6:55 pm
MKE
-
TYS
7h 25m
2 stops
$284Southwest
Wed, Aug 19 - Tue, Aug 25
Southwest Logo
7:10 am - 10:10 am
TYS
-
MKE
4h 00m
1 stop
Southwest Logo
7:00 am - 12:00 pm
MKE
-
TYS
4h 00m
1 stop
$289Southwest
Fri, Aug 21 - Mon, Aug 24
Southwest Logo
12:40 pm - 8:40 pm
TYS
-
MKE
9h 00m
2 stops
Southwest Logo
5:35 am - 5:10 pm
MKE
-
TYS
10h 35m
1 stop
$290Southwest
Mon, Aug 24 - Mon, Aug 31
Southwest Logo
1:00 pm - 8:45 pm
TYS
-
MKE
8h 45m
1 stop
Southwest Logo
6:25 am - 5:10 pm
MKE
-
TYS
9h 45m
2 stops
$294Southwest
Fri, Aug 21 - Mon, Aug 24
Southwest Logo
12:40 pm - 8:40 pm
TYS
-
MKE
9h 00m
2 stops
Southwest Logo
7:50 am - 7:50 pm
MKE
-
TYS
11h 00m
1 stop
$295Southwest
Fri, Aug 28 - Tue, Sep 8
United Airlines Logo
4:16 pm - 11:37 pm
TYS
-
MKE
8h 21m
1 stop
United Airlines Logo
3:52 pm - 8:49 pm
MKE
-
TYS
3h 57m
1 stop
$299United Airlines
Fri, Oct 2 - Mon, Oct 5
Delta Logo
12:23 pm - 5:31 pm
TYS
-
MKE
6h 08m
1 stop
Delta Logo
12:45 pm - 8:15 pm
MKE
-
TYS
6h 30m
1 stop
$301Delta
Mon, Sep 14 - Thu, Sep 17
Southwest Logo
7:10 am - 5:40 pm
TYS
-
MKE
11h 30m
2 stops
Southwest Logo
7:00 am - 5:10 pm
MKE
-
TYS
9h 10m
2 stops
$305Southwest
Fri, Aug 21 - Mon, Aug 24

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American Airlines flights from Knoxville to Milwaukee

Our best American Airlines deals on Knoxville to Milwaukee flight tickets
American Airlines
Aug 6
TYS6:05 pmKnoxville McGhee Tyson
4h 42m
1 stop
MKE9:47 pmMilwaukee-Mitchell
Aug 10
MKE6:00 amMilwaukee-Mitchell
4h 10m
1 stop
TYS11:10 amKnoxville McGhee Tyson
$306
American Airlines
Aug 3
TYS6:32 pmKnoxville McGhee Tyson
4h 49m
1 stop
MKE10:21 pmMilwaukee-Mitchell
Aug 7
MKE2:49 pmMilwaukee-Mitchell
5h 10m
1 stop
TYS8:59 pmKnoxville McGhee Tyson
$323
American Airlines
Aug 7
TYS6:05 pmKnoxville McGhee Tyson
4h 42m
1 stop
MKE9:47 pmMilwaukee-Mitchell
Aug 9
MKE5:16 amMilwaukee-Mitchell
4h 50m
1 stop
TYS11:06 amKnoxville McGhee Tyson
$341

Southwest flights from Knoxville to Milwaukee

Our best Southwest deals on Knoxville to Milwaukee flight tickets
Southwest
Aug 19
TYS7:00 amKnoxville McGhee Tyson
3h 50m
1 stop
MKE9:50 amMilwaukee-Mitchell
Aug 25
MKE10:30 amMilwaukee-Mitchell
7h 25m
2 stops
TYS6:55 pmKnoxville McGhee Tyson
$284
Southwest
Aug 21
TYS7:10 amKnoxville McGhee Tyson
4h 00m
1 stop
MKE10:10 amMilwaukee-Mitchell
Aug 24
MKE7:00 amMilwaukee-Mitchell
4h 00m
1 stop
TYS12:00 pmKnoxville McGhee Tyson
$289
Southwest
Aug 24
TYS12:40 pmKnoxville McGhee Tyson
9h 00m
2 stops
MKE8:40 pmMilwaukee-Mitchell
Aug 31
MKE5:35 amMilwaukee-Mitchell
10h 35m
1 stop
TYS5:10 pmKnoxville McGhee Tyson
$290

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Knoxville to Milwaukee that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Sat 9/5

7:00 am-10:00 am

1 stop4h 00m

Milwaukee-Mitchell

Tue 9/8

6:47 pm-12:23 am

1 stop4h 36m

$274

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Mon 8/17

7:00 am-10:00 am

1 stop4h 00m

Milwaukee-Mitchell

Mon 8/24

1:19 pm-8:53 pm

1 stop6h 34m

$279

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Wed 8/19

7:00 am-9:50 am

1 stop3h 50m

Milwaukee-Mitchell

Tue 8/25

10:30 am-6:55 pm

2 stops7h 25m

$284
Quickest round-trip

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 8/21

7:10 am-10:10 am

1 stop4h 00m

Milwaukee-Mitchell

Mon 8/24

7:00 am-12:00 pm

1 stop4h 00m

$289

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Mon 8/24

12:40 pm-8:40 pm

2 stops9h 00m

Milwaukee-Mitchell

Mon 8/31

5:35 am-5:10 pm

1 stop10h 35m

$290

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 8/21

1:00 pm-8:45 pm

1 stop8h 45m

Milwaukee-Mitchell

Mon 8/24

6:25 am-5:10 pm

2 stops9h 45m

$294

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 8/28

12:40 pm-8:40 pm

2 stops9h 00m

Milwaukee-Mitchell

Tue 9/8

7:50 am-7:50 pm

1 stop11h 00m

$295

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 10/2

4:16 pm-11:37 pm

1 stop8h 21m

Milwaukee-Mitchell

Mon 10/5

3:52 pm-8:49 pm

1 stop3h 57m

$299

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Mon 9/14

12:23 pm-5:31 pm

1 stop6h 08m

Milwaukee-Mitchell

Thu 9/17

12:45 pm-8:15 pm

1 stop6h 30m

$301

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 8/21

7:10 am-5:40 pm

2 stops11h 30m

Milwaukee-Mitchell

Mon 8/24

7:00 am-5:10 pm

2 stops9h 10m

$305

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Milwaukee from

How to get the cheapest flight ticket from Knoxville to Milwaukee

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Milwaukee?

What is the cheapest month to fly to Milwaukee?

The cheapest month to fly to Milwaukee from Knoxville is in January. Flight prices, which tend to average around $208, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Milwaukee, with average flight prices from Knoxville averaging around $228.

How have Knoxville to Milwaukee flight prices changed over time?

As of July 2026, prices for Knoxville to Milwaukee flights are approximately 91% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Milwaukee

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Milwaukee according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Milwaukee (TYS to MKE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Milwaukee

Fastest flight time

3h 50m

Direct flights

None
The fastest flight from Knoxville to Milwaukee takes 3h 50m
There are no direct flights from Knoxville to Milwaukee. There are no popular flight routes from Knoxville to Milwaukee.
Search flight deals

Frequently asked questions about flying from Knoxville to Milwaukee

  • How far is Knoxville McGhee Tyson to Milwaukee-Mitchell by plane?

    Milwaukee-Mitchell is 532.7 mi away from Knoxville McGhee Tyson. By plane, this route typically takes 3h 50m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport.

  • What documentation or ID do you need to fly to Milwaukee-Mitchell Airport?

    The required travel and health documents for your Milwaukee-Mitchell Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Milwaukee-Mitchell Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Milwaukee?

Best airlines flying from Knoxville to Milwaukee

Compare and see reviews for airlines that fly from Knoxville to Milwaukee with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.8
8,476 reviews
Search Delta flights
United AirlinesPriceFrom $204Free CancellationRating
7.4
10,020 reviews
Search United Airlines flights
American AirlinesPriceFrom $208Free CancellationRating
7.1
11,834 reviews
Search American Airlines flights
SouthwestPriceFrom $274Free CancellationRating
8.0
4,241 reviews
Search Southwest flights

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
Waukesha
Wauwatosa
Oak Creek
Mequon
Glendale
West Bend
Port Washington
Pewaukee
Kohler
New Berlin
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Milwaukee?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Milwaukee. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Milwaukee with flexible booking policies on momondo?

momondo does allow users to show only those flights to Milwaukee from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Milwaukee?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Milwaukee from Knoxville.

I’m not ready to book a flight from Knoxville to Milwaukee right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Milwaukee now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Milwaukee and let you know when they change.

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