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Cheap flights from Knoxville to Milwaukee from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Milwaukee departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Milwaukee

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:45 am - 10:30 am
TYS
-
MKE
4h 45m
1 stop
United Airlines Logo
5:00 am - 10:19 am
MKE
-
TYS
4h 19m
1 stop
$209United Airlines
Sat, Feb 14 - Sun, Feb 15
American Airlines Logo
11:45 am - 7:59 pm
TYS
-
MKE
9h 14m
2 stops
American Airlines Logo
6:00 am - 10:45 am
MKE
-
TYS
3h 45m
1 stop
$214American Airlines
Sat, Feb 14 - Sun, Feb 15
United Airlines Logo
10:55 am - 2:05 pm
TYS
-
MKE
4h 10m
1 stop
United Airlines Logo
4:00 pm - 8:37 pm
MKE
-
TYS
3h 37m
1 stop
$224United Airlines
Thu, Feb 12 - Sat, Feb 14
Delta Logo
1:00 pm - 4:08 pm
TYS
-
MKE
4h 08m
1 stop
Delta Logo
3:57 pm - 11:52 pm
MKE
-
TYS
6h 55m
1 stop
$225Delta
Fri, Feb 27 - Sun, Mar 1
American Airlines Logo
6:21 pm - 11:38 pm
TYS
-
MKE
6h 17m
1 stop
American Airlines Logo
5:00 am - 10:45 am
MKE
-
TYS
4h 45m
1 stop
$233American Airlines
Mon, Feb 23 - Thu, Feb 26
United Airlines Logo
11:07 am - 3:43 pm
TYS
-
MKE
5h 36m
1 stop
United Airlines Logo
2:32 pm - 8:52 pm
MKE
-
TYS
5h 20m
1 stop
$239United Airlines
Sat, Feb 7 - Wed, Feb 11
American Airlines Logo
4:06 pm - 10:02 pm
TYS
-
MKE
6h 56m
2 stops
American Airlines Logo
7:32 am - 12:46 pm
MKE
-
TYS
4h 14m
1 stop
$244American Airlines
Sat, Feb 7 - Wed, Feb 11
American Airlines Logo
4:06 pm - 10:02 pm
TYS
-
MKE
6h 56m
2 stops
American Airlines Logo
9:33 am - 4:49 pm
MKE
-
TYS
6h 16m
2 stops
$250American Airlines
Sat, Feb 7 - Wed, Feb 11
Delta Logo
5:40 am - 9:04 am
TYS
-
MKE
4h 24m
1 stop
Delta Logo
6:46 pm - 11:57 pm
MKE
-
TYS
4h 11m
1 stop
$252Delta
Fri, Mar 27 - Mon, Mar 30
Southwest Logo
7:25 pm - 12:05 am
TYS
-
MKE
5h 40m
1 stop
Southwest Logo
6:50 am - 6:45 pm
MKE
-
TYS
10h 55m
2 stops
$278Southwest
Fri, Mar 20 - Mon, Mar 23

Southwest flights from Knoxville to Milwaukee

Our best Southwest deals on Knoxville to Milwaukee flight tickets
Southwest
Mar 20
TYS7:25 pmKnoxville McGhee Tyson
5h 40m
1 stop
MKE12:05 amMilwaukee-Mitchell
Mar 23
MKE6:50 amMilwaukee-Mitchell
10h 55m
2 stops
TYS6:45 pmKnoxville McGhee Tyson
$278
Southwest
Mar 13
TYS7:50 amKnoxville McGhee Tyson
4h 45m
1 stop
MKE11:35 amMilwaukee-Mitchell
Mar 16
MKE4:20 pmMilwaukee-Mitchell
4h 50m
1 stop
TYS10:10 pmKnoxville McGhee Tyson
$281
Southwest
Mar 20
TYS6:30 amKnoxville McGhee Tyson
6h 15m
2 stops
MKE11:45 amMilwaukee-Mitchell
Mar 23
MKE6:50 amMilwaukee-Mitchell
10h 55m
2 stops
TYS6:45 pmKnoxville McGhee Tyson
$294

Delta flights from Knoxville to Milwaukee

Our best Delta deals on Knoxville to Milwaukee flight tickets
Delta
Feb 27
TYS1:00 pmKnoxville McGhee Tyson
4h 08m
1 stop
MKE4:08 pmMilwaukee-Mitchell
Mar 1
MKE3:57 pmMilwaukee-Mitchell
6h 55m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
$225
Delta
Mar 27
TYS5:40 amKnoxville McGhee Tyson
4h 24m
1 stop
MKE9:04 amMilwaukee-Mitchell
Mar 30
MKE6:46 pmMilwaukee-Mitchell
4h 11m
1 stop
TYS11:57 pmKnoxville McGhee Tyson
$252

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 25, 2026.
Use the filters below to find and compare flights from Knoxville to Milwaukee that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Sat 2/14

6:45 am-10:30 am

1 stop4h 45m

Milwaukee-Mitchell

Sun 2/15

5:00 am-10:19 am

1 stop4h 19m

$209

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Sat 2/14

11:45 am-7:59 pm

2 stops9h 14m

Milwaukee-Mitchell

Sun 2/15

6:00 am-10:45 am

1 stop3h 45m

$214

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Thu 2/12

10:55 am-2:05 pm

1 stop4h 10m

Milwaukee-Mitchell

Sat 2/14

4:00 pm-8:37 pm

1 stop3h 37m

$224

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 2/27

1:00 pm-4:08 pm

1 stop4h 08m

Milwaukee-Mitchell

Sun 3/1

3:57 pm-11:52 pm

1 stop6h 55m

$225

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Mon 2/23

6:21 pm-11:38 pm

1 stop6h 17m

Milwaukee-Mitchell

Thu 2/26

5:00 am-10:45 am

1 stop4h 45m

$233

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Sat 2/7

11:07 am-3:43 pm

1 stop5h 36m

Milwaukee-Mitchell

Wed 2/11

2:32 pm-8:52 pm

1 stop5h 20m

$239

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Sat 2/7

4:06 pm-10:02 pm

2 stops6h 56m

Milwaukee-Mitchell

Wed 2/11

7:32 am-12:46 pm

1 stop4h 14m

$244

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Sat 2/7

4:06 pm-10:02 pm

2 stops6h 56m

Milwaukee-Mitchell

Wed 2/11

9:33 am-4:49 pm

2 stops6h 16m

$250

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 3/27

5:40 am-9:04 am

1 stop4h 24m

Milwaukee-Mitchell

Mon 3/30

6:46 pm-11:57 pm

1 stop4h 11m

$252

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 3/20

7:25 pm-12:05 am

1 stop5h 40m

Milwaukee-Mitchell

Mon 3/23

6:50 am-6:45 pm

2 stops10h 55m

$278

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Milwaukee from

How to get the cheapest flight ticket from Knoxville to Milwaukee

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Milwaukee?

The cheapest month to fly to Milwaukee from Knoxville is in January. Flight prices, which tend to average around $233, are often lower during this time because this is during the off-season. The month of November is another great option to travel to Milwaukee, with average flight prices from Knoxville averaging around $262.

How have Knoxville to Milwaukee flight prices changed over time?

As of January 2026, prices for Knoxville to Milwaukee flights are approximately 53% cheaper when compared to flights at the same time last year.

When to book flights from Knoxville to Milwaukee

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Milwaukee according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Milwaukee (TYS to MKE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Milwaukee

Fastest flight time

3h 43m

Direct flights

None
The fastest flight from Knoxville to Milwaukee takes 3h 43m
There are no direct flights from Knoxville to Milwaukee. There are no popular flight routes from Knoxville to Milwaukee.
Search flight deals

  • How far is Knoxville McGhee Tyson to Milwaukee-Mitchell by plane?

    Milwaukee-Mitchell is 532.7 mi away from Knoxville McGhee Tyson. By plane, this route typically takes 3h 43m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport.

  • What documentation or ID do you need to fly to Milwaukee-Mitchell Airport?

    The required travel and health documents for your Milwaukee-Mitchell Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Milwaukee-Mitchell Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Milwaukee?

Best airlines flying from Knoxville to Milwaukee

Compare and see reviews for airlines that fly from Knoxville to Milwaukee with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,111 reviews
Search Delta flights
United AirlinesPriceFrom $204Free CancellationRating
7.4
9,198 reviews
Search United Airlines flights
American AirlinesPriceFrom $208Free CancellationRating
7.2
11,197 reviews
Search American Airlines flights

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
Waukesha
Wauwatosa
Oak Creek
Mequon
Glendale
Pewaukee
Kohler
West Bend
Port Washington
New Berlin
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Milwaukee?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Milwaukee. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Milwaukee with flexible booking policies on momondo?

momondo does allow users to show only those flights to Milwaukee from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Milwaukee?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Milwaukee from Knoxville.

I’m not ready to book a flight from Knoxville to Milwaukee right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Milwaukee now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Milwaukee and let you know when they change.

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