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Cheap flights from Knoxville to Milwaukee from $139

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Milwaukee departing on 4/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Milwaukee

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:30 am - 12:29 pm
TYS
-
MKE
5h 59m1 stop
Delta Logo
1:18 pm - 8:47 pm
MKE
-
TYS
6h 29m1 stop
$209Delta
Tue, Jan 20 - Thu, Jan 29
American Airlines Logo
6:00 am - 11:17 am
TYS
-
MKE
6h 17m1 stop
American Airlines Logo
6:00 am - 1:54 pm
MKE
-
TYS
6h 54m2 stops
$214American Airlines
Thu, Jan 8 - Mon, Jan 12
American Airlines Logo
12:15 pm - 6:26 pm
TYS
-
MKE
7h 11m2 stops
American Airlines Logo
6:00 am - 1:54 pm
MKE
-
TYS
6h 54m2 stops
$219American Airlines
Thu, Jan 8 - Tue, Jan 13
American Airlines Logo
5:23 am - 11:03 am
TYS
-
MKE
6h 40m1 stop
American Airlines Logo
6:11 am - 3:20 pm
MKE
-
TYS
8h 09m2 stops
$239American Airlines
Thu, Jan 1 - Tue, Jan 6
United Airlines Logo
6:45 am - 12:09 pm
TYS
-
MKE
6h 24m1 stop
United Airlines Logo
2:32 pm - 8:52 pm
MKE
-
TYS
5h 20m1 stop
$277United Airlines
Mon, Jan 19 - Fri, Jan 23
United Airlines Logo
11:10 am - 1:53 pm
TYS
-
MKE
3h 43m1 stop
United Airlines Logo
3:20 pm - 8:52 pm
MKE
-
TYS
4h 32m1 stop
$279United Airlines
Tue, Jan 27 - Sat, Jan 31
American Airlines Logo
4:00 pm - 10:05 pm
TYS
-
MKE
7h 05m2 stops
American Airlines Logo
3:53 pm - 10:47 pm
MKE
-
TYS
5h 54m1 stop
$289American Airlines
Tue, Jan 20 - Thu, Jan 29
United Airlines Logo
6:45 am - 10:34 am
TYS
-
MKE
4h 49m1 stop
United Airlines Logo
3:20 pm - 8:52 pm
MKE
-
TYS
4h 32m1 stop
$291United Airlines
Fri, Jan 16 - Fri, Jan 16
American Airlines Logo
4:00 pm - 10:05 pm
TYS
-
MKE
7h 05m2 stops
American Airlines Logo
6:00 am - 3:20 pm
MKE
-
TYS
8h 20m2 stops
$294American Airlines
Tue, Jan 20 - Wed, Jan 28
American Airlines Logo
3:02 pm - 5:49 pm
TYS
-
MKE
3h 47m1 stop
American Airlines Logo
6:00 am - 10:50 am
MKE
-
TYS
3h 50m1 stop
$299American Airlines
Thu, Dec 18 - Sat, Dec 20

American Airlines flights from Knoxville to Milwaukee

Our best American Airlines deals on Knoxville to Milwaukee flight tickets
American Airlines
Jan 8
TYS6:00 amKnoxville McGhee Tyson
6h 17m
1 stop
MKE11:17 amMilwaukee-Mitchell
Jan 12
MKE6:00 amMilwaukee-Mitchell
6h 54m
2 stops
TYS1:54 pmKnoxville McGhee Tyson
$214
Find similar
American Airlines
Jan 8
TYS12:15 pmKnoxville McGhee Tyson
7h 11m
2 stops
MKE6:26 pmMilwaukee-Mitchell
Jan 13
MKE6:00 amMilwaukee-Mitchell
6h 54m
2 stops
TYS1:54 pmKnoxville McGhee Tyson
$219
Find similar
American Airlines
Jan 1
TYS5:23 amKnoxville McGhee Tyson
6h 40m
1 stop
MKE11:03 amMilwaukee-Mitchell
Jan 6
MKE6:11 amMilwaukee-Mitchell
8h 09m
2 stops
TYS3:20 pmKnoxville McGhee Tyson
$239
Find similar

United Airlines flights from Knoxville to Milwaukee

Our best United Airlines deals on Knoxville to Milwaukee flight tickets
United Airlines
Jan 19
TYS6:45 amKnoxville McGhee Tyson
6h 24m
1 stop
MKE12:09 pmMilwaukee-Mitchell
Jan 23
MKE2:32 pmMilwaukee-Mitchell
5h 20m
1 stop
TYS8:52 pmKnoxville McGhee Tyson
$277
Find similar
United Airlines
Jan 27
TYS11:10 amKnoxville McGhee Tyson
3h 43m
1 stop
MKE1:53 pmMilwaukee-Mitchell
Jan 31
MKE3:20 pmMilwaukee-Mitchell
4h 32m
1 stop
TYS8:52 pmKnoxville McGhee Tyson
$279
Find similar
United Airlines
Jan 16
TYS6:45 amKnoxville McGhee Tyson
4h 49m
1 stop
MKE10:34 amMilwaukee-Mitchell
Jan 16
MKE3:20 pmMilwaukee-Mitchell
4h 32m
1 stop
TYS8:52 pmKnoxville McGhee Tyson
$291
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Knoxville to Milwaukee that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Tue 1/20

7:30 am-12:29 pm

1 stop5h 59m

Milwaukee-Mitchell

Thu 1/29

1:18 pm-8:47 pm

1 stop6h 29m

$209

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Thu 1/8

6:00 am-11:17 am

1 stop6h 17m

Milwaukee-Mitchell

Mon 1/12

6:00 am-1:54 pm

2 stops6h 54m

$214

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Thu 1/8

12:15 pm-6:26 pm

2 stops7h 11m

Milwaukee-Mitchell

Tue 1/13

6:00 am-1:54 pm

2 stops6h 54m

$219

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Thu 1/1

5:23 am-11:03 am

1 stop6h 40m

Milwaukee-Mitchell

Tue 1/6

6:11 am-3:20 pm

2 stops8h 09m

$239

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Mon 1/19

6:45 am-12:09 pm

1 stop6h 24m

Milwaukee-Mitchell

Fri 1/23

2:32 pm-8:52 pm

1 stop5h 20m

$277

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Tue 1/27

11:10 am-1:53 pm

1 stop3h 43m

Milwaukee-Mitchell

Sat 1/31

3:20 pm-8:52 pm

1 stop4h 32m

$279

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Tue 1/20

4:00 pm-10:05 pm

2 stops7h 05m

Milwaukee-Mitchell

Thu 1/29

3:53 pm-10:47 pm

1 stop5h 54m

$289

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Fri 1/16

6:45 am-10:34 am

1 stop4h 49m

Milwaukee-Mitchell

Fri 1/16

3:20 pm-8:52 pm

1 stop4h 32m

$291

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Tue 1/20

4:00 pm-10:05 pm

2 stops7h 05m

Milwaukee-Mitchell

Wed 1/28

6:00 am-3:20 pm

2 stops8h 20m

$294

KnoxvilleMilwaukee

TYS - MKE

TYSMKE

Knoxville McGhee Tyson

Thu 12/18

3:02 pm-5:49 pm

1 stop3h 47m

Milwaukee-Mitchell

Sat 12/20

6:00 am-10:50 am

1 stop3h 50m

$299

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Milwaukee from

How to get the cheapest flight ticket from Knoxville to Milwaukee

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Milwaukee?

The cheapest month to fly to Milwaukee from Knoxville is in December. Flight prices, which tend to average around $213, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Milwaukee, with average flight prices from Knoxville averaging around $225.

What is the cheapest day to depart on your flight to Milwaukee?

According to our data, Tuesday is the cheapest day to fly to Milwaukee from Knoxville. The lowest ticket price found for a Tuesday departure recently was $218. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Flights from Knoxville to Milwaukee on a Monday will generally be more expensive and average around $483. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Milwaukee?

In the evening is the cheapest time of day to fly from Knoxville to Milwaukee when you can find flight prices for as low as $255. Flying to Milwaukee in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Milwaukee, so prices are often more expensive at around $283 per ticket.

How have Knoxville to Milwaukee flight prices changed over time?

As of December 2025, prices for Knoxville to Milwaukee flights are approximately 45% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Milwaukee

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Milwaukee according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Milwaukee (TYS to MKE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Milwaukee

Fastest flight time

3h 43m

Direct flights

None
The fastest flight from Knoxville to Milwaukee takes 3h 43m
There are no direct flights from Knoxville to Milwaukee. There are no popular flight routes from Knoxville to Milwaukee.
Search flight deals

  • How far is Knoxville McGhee Tyson to Milwaukee-Mitchell by plane?

    Milwaukee-Mitchell is 532.7 mi away from Knoxville McGhee Tyson. By plane, this route typically takes 3h 43m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Milwaukee-Mitchell Airport.

  • What documentation or ID do you need to fly to Milwaukee-Mitchell Airport?

    The required travel and health documents for your Milwaukee-Mitchell Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Milwaukee-Mitchell Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Milwaukee?

Best airlines flying from Knoxville to Milwaukee

Compare and see reviews for airlines that fly from Knoxville to Milwaukee with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,013 reviews
Search Delta flights
United AirlinesPriceFrom $204Free CancellationRating
7.4
9,076 reviews
Search United Airlines flights
American AirlinesPriceFrom $208Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
Waukesha
Wauwatosa
Oak Creek
Mequon
Glendale
Pewaukee
Kohler
Port Washington
West Bend
New Berlin
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Milwaukee?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Milwaukee. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Milwaukee with flexible booking policies on momondo?

momondo does allow users to show only those flights to Milwaukee from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Milwaukee?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Milwaukee from Knoxville.

I’m not ready to book a flight from Knoxville to Milwaukee right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Milwaukee now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Milwaukee and let you know when they change.

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