What airlines fly to Indiana?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Indiana from Knoxville according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 4 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Indiana?

Southwest, Delta, and Allegiant Air are the most popular carriers operating from Knoxville McGhee Tyson to Indiana

How many flights depart from Knoxville to Indiana on average per week?

As of March 2026, 76 flights take off from Knoxville and land in Indiana each week. The most common flight departure day for this route is Thu, with 37% of weekly flights taking off on this day.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Indiana?

Prices for flights from Knoxville McGhee Tyson Airport to Indiana are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Indiana?

There are 4 operators available for flights from Knoxville McGhee Tyson Airport to Indiana as of March 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Indiana?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Indiana.

What documentation or ID do you need to fly to Indiana?

The travel and health documents required for your trip to Indiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$60 Cheap Flights from Knoxville to Indiana in 2026

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Find the cheapest flights from Knoxville to Indiana

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 7:55 am

TYS

ORD

1h 55mnonstop

7:15 am - 10:08 am

ORD

TYS

1h 53mnonstop

$189United Airlines

jue., abr. 9 - dom., abr. 12

7:00 am - 8:00 am

TYS

ORD

2h 00mnonstop

6:06 pm - 8:47 pm

ORD

TYS

1h 41mnonstop

$204United Airlines

vie., mar. 20 - mar., mar. 24

11:27 am - 10:21 pm

TYS

MDW

11h 54m

2 stops

2:47 pm - 5:13 pm

MDW

TYS

1h 26mnonstop

$205Multiple Airlines

jue., abr. 9 - jue., may. 21

7:10 am - 1:00 pm

TYS

MDW

6h 50m

1 stop

2:46 pm - 5:14 pm

MDW

TYS

1h 28mnonstop

$207Multiple Airlines

lun., may. 11 - jue., jun. 4

8:48 pm - 9:57 pm

TYS

ORD

2h 09mnonstop

6:30 pm - 9:21 pm

ORD

TYS

1h 51mnonstop

$208American Airlines

vie., abr. 17 - vie., abr. 24

5:24 pm - 8:17 pm

TYS

ORD

3h 53m

1 stop

7:07 am - 2:33 pm

ORD

TYS

6h 26m

1 stop

$209Delta

jue., abr. 9 - dom., may. 10

7:00 am - 6:22 pm

TYS

MDW

12h 22m

1 stop

2:47 pm - 5:13 pm

MDW

TYS

1h 26mnonstop

$218Allegiant Air

jue., abr. 23 - jue., may. 28

7:27 pm - 8:41 am

TYS

SBN

13h 14m

1 stop

9:31 am - 10:41 am

SBN

TYS

25h 10m

1 stop

$223Allegiant Air

jue., may. 28 - lun., jun. 1

11:18 am - 4:43 pm

TYS

ORD

6h 25m

1 stop

9:50 am - 4:43 pm

ORD

TYS

5h 53m

1 stop

$224Delta

vie., mar. 20 - mar., mar. 24

7:07 am - 11:22 am

TYS

AZO

4h 15m

1 stop

3:47 pm - 9:56 pm

AZO

TYS

6h 09m

1 stop

$437American Airlines

dom., jun. 28 - dom., jul. 5

Delta flights from Knoxville to Indiana

Our best Delta deals on Knoxville to Indiana flight tickets

Delta

Apr 9

TYS5:24 pmKnoxville McGhee Tyson

3h 53m

1 stop

ORD8:17 pmChicago O'Hare Intl

May 16

ORD8:10 amChicago O'Hare Intl

5h 55m

1 stop

TYS3:05 pmKnoxville McGhee Tyson

$209

Delta

Mar 20

TYS11:18 amKnoxville McGhee Tyson

6h 25m

1 stop

ORD4:43 pmChicago O'Hare Intl

Mar 24

ORD9:50 amChicago O'Hare Intl

5h 53m

1 stop

TYS4:43 pmKnoxville McGhee Tyson

$224

Delta

Apr 18

TYS5:15 pmKnoxville McGhee Tyson

4h 01m

1 stop

ORD8:16 pmChicago O'Hare Intl

Apr 25

ORD5:59 pmChicago O'Hare Intl

4h 55m

1 stop

TYS11:54 pmKnoxville McGhee Tyson

$229

United Airlines flights from Knoxville to Indiana

Our best United Airlines deals on Knoxville to Indiana flight tickets

United Airlines

Apr 9

TYS7:00 amKnoxville McGhee Tyson

1h 55m

ORD7:55 amChicago O'Hare Intl

Apr 12

ORD7:15 amChicago O'Hare Intl

1h 53m

TYS10:08 amKnoxville McGhee Tyson

$189

United Airlines

Mar 20

TYS7:00 amKnoxville McGhee Tyson

2h 00m

ORD8:00 amChicago O'Hare Intl

Mar 24

ORD6:06 pmChicago O'Hare Intl

1h 41m

TYS8:47 pmKnoxville McGhee Tyson

$204

United Airlines

Apr 3

TYS7:00 amKnoxville McGhee Tyson

1h 55m

ORD7:55 amChicago O'Hare Intl

Apr 5

ORD7:15 amChicago O'Hare Intl

1h 53m

TYS10:08 amKnoxville McGhee Tyson

$223

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

jue. 4/9

7:00 am-7:55 am

Nonstop1h 55m

Chicago O'Hare Intl

dom. 4/12

7:15 am-10:08 am

Nonstop1h 53m

$189

Quickest round-trip

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

vie. 3/20

7:00 am-8:00 am

Nonstop2h 00m

Chicago O'Hare Intl

mar. 3/24

6:06 pm-8:47 pm

Nonstop1h 41m

$204

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

jue. 4/9

11:27 am-10:21 pm

2 stops11h 54m

Chicago Midway

jue. 5/21

2:47 pm-5:13 pm

Nonstop1h 26m

$205

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

lun. 5/11

7:10 am-1:00 pm

1 stop6h 50m

Chicago Midway

jue. 6/4

2:46 pm-5:14 pm

Nonstop1h 28m

$207

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

vie. 4/17

8:48 pm-9:57 pm

Nonstop2h 09m

Chicago O'Hare Intl

vie. 4/24

6:30 pm-9:21 pm

Nonstop1h 51m

$208

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

jue. 4/9

5:24 pm-8:17 pm

1 stop3h 53m

Chicago O'Hare Intl

dom. 5/10

7:07 am-2:33 pm

1 stop6h 26m

$209

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

jue. 4/23

7:00 am-6:22 pm

1 stop12h 22m

Chicago Midway

jue. 5/28

2:47 pm-5:13 pm

Nonstop1h 26m

$218

KnoxvilleSouth Bend

TYS - SBN

TYSSBN

Knoxville McGhee Tyson

jue. 5/28

7:27 pm-8:41 am

1 stop13h 14m

South Bend/Michiana

lun. 6/1

9:31 am-10:41 am

1 stop25h 10m

$223

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

vie. 3/20

11:18 am-4:43 pm

1 stop6h 25m

Chicago O'Hare Intl

mar. 3/24

9:50 am-4:43 pm

1 stop5h 53m

$224

KnoxvilleKalamazoo

TYS - AZO

TYSAZO

Knoxville McGhee Tyson

dom. 6/28

7:07 am-11:22 am

1 stop4h 15m

Kalamazoo Intl

dom. 7/5

3:47 pm-9:56 pm

1 stop6h 09m

$437

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from Knoxville is in April. Flight prices, which tend to average around $233, are often lower during this time because this is during the off-season. The month of May is another great option to travel to Indiana, with average flight prices from Knoxville averaging around $246.

What is the cheapest Knoxville McGhee Tyson to Indiana flight route?

Fly from Knoxville McGhee Tyson to South Bend/Michiana for the best Knoxville McGhee Tyson - Indiana flight prices

What cabin class options are available on Knoxville McGhee Tyson to Indiana flights?

There is only 1 cabin class available to choose from on Knoxville McGhee Tyson to Indiana flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Indiana flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Indiana.

Cheap Knoxville to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Indiana

Fastest flight time	1h 34m
Direct flights	Every day
Airports in Indiana	94 airports

The fastest flight from Knoxville to Indiana takes 1h 34m

Direct flights go from Knoxville to Indiana every day.

There are 94 airports in Indiana. From Knoxville there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).

Search flight deals

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Indiana?
Prices for flights from Knoxville McGhee Tyson Airport to Indiana are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Indiana?
There are 4 operators available for flights from Knoxville McGhee Tyson Airport to Indiana as of March 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Indiana?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Indiana.
What documentation or ID do you need to fly to Indiana?
The travel and health documents required for your trip to Indiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Knoxville to Indiana?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Knoxville to Indiana is Airbus A320-100/200 (100.00% of total bookings).

Best airlines flying from Knoxville to Indiana

Compare and see reviews for airlines that fly from Knoxville to Indiana with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $31	Free Cancellation	Rating 7.3 717 reviews	Search Allegiant Air flights
United Airlines	PriceFrom $208	Free Cancellation	Rating 7.4 9,388 reviews	Search United Airlines flights
Delta	PriceFrom $208	Free Cancellation	Rating 7.9 8,249 reviews	Search Delta flights
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.1 11,381 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Indiana?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Indiana from Knoxville.

Can I find flights from Knoxville to Indiana with flexible booking policies on momondo?

All flight searches from Knoxville to Indiana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Indiana?

momondo helps you find the best flight between Knoxville and Indiana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Indiana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Indiana, momondo offers a useful price alert feature which will track prices for flights to Indiana from Knoxville and alert you when they change.