How many flights depart from Knoxville to Indiana on average per week?

As of June 2026, 217 flights take off from Knoxville and land in Indiana each week. The most common flight departure day for this route is Thu, with 16% of weekly flights taking off on this day.

What airlines fly to Indiana?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Indiana from Knoxville according to our data. American Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 4 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Indiana?

Allegiant Air, Southwest, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Indiana

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Indiana?

Prices for flights from Knoxville McGhee Tyson Airport to Indiana are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Indiana?

There are 4 operators available for flights from Knoxville McGhee Tyson Airport to Indiana as of June 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Indiana?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Indiana.

What documentation or ID do you need to fly to Indiana?

The travel and health documents required for your trip to Indiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$67 Cheap Flights from Knoxville to Indiana in 2026

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Knoxville to Indiana

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:22 pm - 1:58 pm

TYS

MDW

1h 36mnonstop

2:48 pm - 5:18 pm

MDW

TYS

1h 30mnonstop

$163Allegiant Air

Thu, Jul 2 - Thu, Jul 9

1:22 pm - 1:58 pm

TYS

MDW

1h 36mnonstop

2:48 pm - 5:18 pm

MDW

TYS

1h 30mnonstop

$174Allegiant Air

Thu, Jul 2 - Sun, Jul 5

7:20 pm - 9:58 am

TYS

IND

14h 38m

1 stop

7:00 am - 11:19 pm

IND

TYS

16h 19m

1 stop

$220Multiple Airlines

Fri, Jul 10 - Mon, Jul 13

1:21 pm - 11:14 pm

TYS

ORD

10h 53m

1 stop

5:30 pm - 2:59 pm

ORD

TYS

20h 29m

1 stop

$227Multiple Airlines

Thu, Aug 20 - Tue, Aug 25

6:00 am - 6:59 am

TYS

ORD

1h 59mnonstop

5:55 pm - 8:44 pm

ORD

TYS

1h 49mnonstop

$249United Airlines

Thu, Jul 2 - Thu, Jul 9

6:43 pm - 7:59 pm

TYS

ORD

2h 16mnonstop

8:05 am - 10:58 am

ORD

TYS

1h 53mnonstop

$250American Airlines

Thu, Jun 25 - Sun, Jun 28

1:00 pm - 1:59 pm

TYS

ORD

1h 59mnonstop

5:07 am - 10:38 am

ORD

TYS

4h 31m

1 stop

$259American Airlines

Thu, Jul 2 - Sun, Jul 5

5:25 pm - 8:50 pm

TYS

SBN

3h 25m

1 stop

8:20 am - 2:09 pm

SBN

TYS

5h 49m

1 stop

$269Delta

Fri, Jul 3 - Mon, Jul 6

7:15 am - 1:00 pm

TYS

ORD

6h 45m

1 stop

6:22 pm - 11:52 pm

ORD

TYS

4h 30m

1 stop

$269Delta

Thu, Jul 2 - Thu, Jul 9

6:00 am - 12:26 pm

TYS

SBN

6h 26m

1 stop

3:15 pm - 8:56 pm

SBN

TYS

5h 41m

1 stop

$299United Airlines

Tue, Jun 16 - Sat, Jun 20

American Airlines flights from Knoxville to Indiana

Our best American Airlines deals on Knoxville to Indiana flight tickets

American Airlines

Jun 25

TYS6:43 pmKnoxville McGhee Tyson

2h 16m

ORD7:59 pmChicago O'Hare Intl

Jun 28

ORD8:05 amChicago O'Hare Intl

1h 53m

TYS10:58 amKnoxville McGhee Tyson

$250

American Airlines

Jul 2

TYS1:00 pmKnoxville McGhee Tyson

1h 59m

ORD1:59 pmChicago O'Hare Intl

Jul 5

ORD5:07 amChicago O'Hare Intl

4h 31m

1 stop

TYS10:38 amKnoxville McGhee Tyson

$259

American Airlines

Jul 2

TYS6:32 pmKnoxville McGhee Tyson

2h 18m

ORD7:50 pmChicago O'Hare Intl

Jul 5

ORD8:15 amChicago O'Hare Intl

1h 50m

TYS11:05 amKnoxville McGhee Tyson

$264

United Airlines flights from Knoxville to Indiana

Our best United Airlines deals on Knoxville to Indiana flight tickets

United Airlines

Jul 2

TYS6:00 amKnoxville McGhee Tyson

1h 59m

ORD6:59 amChicago O'Hare Intl

Jul 9

ORD5:55 pmChicago O'Hare Intl

1h 49m

TYS8:44 pmKnoxville McGhee Tyson

$249

United Airlines

Jun 18

TYS6:00 amKnoxville McGhee Tyson

1h 59m

ORD6:59 amChicago O'Hare Intl

Jun 21

ORD6:07 pmChicago O'Hare Intl

1h 49m

TYS8:56 pmKnoxville McGhee Tyson

$275

United Airlines

Sep 25

TYS6:00 amKnoxville McGhee Tyson

4h 56m

1 stop

IND10:56 amIndianapolis

Sep 28

IND4:35 pmIndianapolis

4h 25m

1 stop

TYS9:00 pmKnoxville McGhee Tyson

$278

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 7/2

1:22 pm-1:58 pm

Nonstop1h 36m

Chicago Midway

Thu 7/9

2:48 pm-5:18 pm

Nonstop1h 30m

$163

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 7/2

1:22 pm-1:58 pm

Nonstop1h 36m

Chicago Midway

Sun 7/5

2:48 pm-5:18 pm

Nonstop1h 30m

$174

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Fri 7/10

7:20 pm-9:58 am

1 stop14h 38m

Indianapolis

Mon 7/13

7:00 am-11:19 pm

1 stop16h 19m

$220

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 8/20

1:21 pm-11:14 pm

1 stop10h 53m

Chicago O'Hare Intl

Tue 8/25

5:30 pm-2:59 pm

1 stop20h 29m

$227

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 7/2

6:00 am-6:59 am

Nonstop1h 59m

Chicago O'Hare Intl

Thu 7/9

5:55 pm-8:44 pm

Nonstop1h 49m

$249

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 6/25

6:43 pm-7:59 pm

Nonstop2h 16m

Chicago O'Hare Intl

Sun 6/28

8:05 am-10:58 am

Nonstop1h 53m

$250

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 7/2

1:00 pm-1:59 pm

Nonstop1h 59m

Chicago O'Hare Intl

Sun 7/5

5:07 am-10:38 am

1 stop4h 31m

$259

KnoxvilleSouth Bend

TYS - SBN

TYSSBN

Knoxville McGhee Tyson

Fri 7/3

5:25 pm-8:50 pm

1 stop3h 25m

South Bend/Michiana

Mon 7/6

8:20 am-2:09 pm

1 stop5h 49m

$269

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 7/2

7:15 am-1:00 pm

1 stop6h 45m

Chicago O'Hare Intl

Thu 7/9

6:22 pm-11:52 pm

1 stop4h 30m

$269

KnoxvilleSouth Bend

TYS - SBN

TYSSBN

Knoxville McGhee Tyson

Tue 6/16

6:00 am-12:26 pm

1 stop6h 26m

South Bend/Michiana

Sat 6/20

3:15 pm-8:56 pm

1 stop5h 41m

$299

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from Knoxville is in July. Flight prices, which tend to average around $31, are often lower during this time because this is during the off-season. The month of June is another great option to travel to Indiana, with average flight prices from Knoxville averaging around $41.

What is the cheapest Knoxville McGhee Tyson to Indiana flight route?

Fly from Knoxville McGhee Tyson to South Bend/Michiana for the best Knoxville McGhee Tyson - Indiana flight prices

What cabin class options are available on Knoxville to Indiana flights?

There is only 1 cabin class available to choose from on Knoxville to Indiana flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Indiana flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Indiana.

Cheap Knoxville to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Indiana

Fastest flight time	1h 32m
Direct flights	Every day
Airports in Indiana	94 airports

The fastest flight from Knoxville to Indiana takes 1h 32m

Direct flights go from Knoxville to Indiana every day.

There are 94 airports in Indiana. From Knoxville there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).

Search flight deals

Frequently asked questions about flying from Knoxville to Indiana

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Indiana?
Prices for flights from Knoxville McGhee Tyson Airport to Indiana are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Indiana?
There are 4 operators available for flights from Knoxville McGhee Tyson Airport to Indiana as of June 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Indiana?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Indiana.
What documentation or ID do you need to fly to Indiana?
The travel and health documents required for your trip to Indiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Knoxville to Indiana?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Knoxville to Indiana is Airbus A320-100/200 (100.00% of total bookings).

Best airlines flying from Knoxville to Indiana

Compare and see reviews for airlines that fly from Knoxville to Indiana with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $31	Free Cancellation	Rating 7.3 706 reviews	Search Allegiant Air flights
United Airlines	PriceFrom $213	Free Cancellation	Rating 7.4 9,778 reviews	Search United Airlines flights
Delta	PriceFrom $218	Free Cancellation	Rating 7.8 8,397 reviews	Search Delta flights
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 11,648 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Indiana?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Indiana from Knoxville.

Can I find flights from Knoxville to Indiana with flexible booking policies on momondo?

All flight searches from Knoxville to Indiana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Indiana?

momondo helps you find the best flight between Knoxville and Indiana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Indiana right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Indiana, momondo offers a useful price alert feature which will track prices for flights to Indiana from Knoxville and alert you when they change.