What is the cheapest airline that flies from Knoxville McGhee Tyson to Louisiana?

Southwest, Delta, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Louisiana

What airlines fly to Louisiana?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to Louisiana from Knoxville according to our data. Delta is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Louisiana. Keep in mind that there are 4 different airlines that fly to Louisiana on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Louisiana?

Prices for flights from Knoxville McGhee Tyson Airport to Louisiana are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Louisiana?

There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Louisiana as of September 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Louisiana?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Louisiana.

What documentation or ID do you need to fly to Louisiana?

The travel and health documents required for your trip to Louisiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$118 Cheap Flights from Knoxville to Louisiana in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Louisiana

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:20 pm - 9:15 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

4h 55m1 stop Houston George Bush Intcntl

8:00 am - 2:42 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

5h 42m1 stop Washington, D.C. Dulles Intl

$282United Airlines

Tue, Feb 23 - Wed, Feb 24

9:28 pm - 10:09 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

25h 41m1 stop Tampa St. Petersburg

9:05 pm - 6:52 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

20h 47m1 stop Orlando

$285Multiple Airlines

Thu, Oct 15 - Mon, Oct 19

5:57 pm - 11:59 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

7h 02m1 stop Charlotte Douglas

8:00 am - 2:09 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

5h 09m1 stop Dallas/Fort Worth

$287American Airlines

Wed, Feb 24 - Mon, Mar 1

6:20 am - 9:27 amTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

4h 07m1 stop Charlotte Douglas

5:41 am - 2:07 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

7h 26m1 stop Dallas/Fort Worth

$287American Airlines

Tue, Oct 13 - Sat, Oct 17

12:00 pm - 4:05 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

5h 05m1 stop Houston George Bush Intcntl

8:00 am - 2:42 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

5h 42m1 stop Washington, D.C. Dulles Intl

$287United Airlines

Wed, Feb 17 - Sat, Feb 20

3:00 pm - 9:35 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

7h 35m1 stop Dallas/Fort Worth

8:00 am - 4:34 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

7h 34m1 stop Dallas/Fort Worth

$287American Airlines

Wed, Feb 24 - Sat, Feb 27

5:40 am - 8:04 amTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

3h 24m1 stop Atlanta Hartsfield-Jackson

5:20 am - 9:34 amMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

3h 14m1 stop Atlanta Hartsfield-Jackson

$301Delta

Wed, Oct 7 - Wed, Oct 14

5:40 am - 8:00 amTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

3h 20m1 stop Atlanta Hartsfield-Jackson

9:05 am - 1:21 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

3h 16m1 stop Atlanta Hartsfield-Jackson

$303Delta

Thu, Oct 1 - Mon, Oct 5

2:40 pm - 9:50 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

8h 10m2 stops Dallas Love Field Houston Hobby

7:30 am - 2:00 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

5h 30m1 stop Dallas Love Field

$304Southwest

Fri, Jan 8 - Mon, Jan 11

2:40 pm - 9:50 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

8h 10m2 stops Dallas Love Field Houston Hobby

6:00 am - 3:45 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

8h 45m1 stop Denver Intl

$304Southwest

Fri, Jan 22 - Mon, Jan 25

Cheap last minute flights

Enter your travel dates to find the best prices.

8:20 am - 6:34 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

11h 14m1 stop Orlando

8:03 pm - 7:34 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

22h 31m2 stops Orlando Philadelphia

$457Multiple Airlines

Fri, Sep 11 - Sun, Sep 13

1:55 pm - 8:05 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

7h 10m1 stop Dallas Love Field

8:30 am - 2:20 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

4h 50m1 stop Dallas Love Field

$463Southwest

Tue, Sep 15 - Tue, Sep 22

5:30 pm - 10:30 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

6h 00m1 stop Nashville Intl

7:10 am - 2:20 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

6h 10m2 stops Houston Hobby Dallas Love Field

$468Southwest

Tue, Sep 15 - Tue, Sep 22

1:55 pm - 10:05 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

9h 10m2 stops Dallas Love Field Houston Hobby

9:45 am - 7:00 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

8h 15m2 stops Orlando Nashville Intl

$473Southwest

Tue, Sep 15 - Tue, Sep 22

9:31 am - 7:07 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

10h 36m1 stop Orlando Sanford Intl

8:03 pm - 7:34 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

22h 31m2 stops Orlando Philadelphia

$483Multiple Airlines

Fri, Sep 11 - Sun, Sep 13

8:20 am - 7:07 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

11h 47m1 stop Orlando

8:03 pm - 8:39 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

23h 36m1 stop Orlando

$486Multiple Airlines

Fri, Sep 11 - Sun, Sep 13

9:31 am - 7:07 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

10h 36m1 stop Orlando Sanford Intl

8:03 pm - 8:39 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

23h 36m1 stop Orlando

$496Multiple Airlines

Fri, Sep 11 - Sun, Sep 13

7:10 am - 12:42 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

6h 32m1 stop Washington, D.C. Reagan-National

10:00 am - 4:42 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

5h 42m1 stop Dallas/Fort Worth

$595American Airlines

Sat, Sep 12 - Mon, Sep 14

7:10 am - 12:42 pmTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

6h 32m1 stop Washington, D.C. Reagan-National

10:00 am - 4:42 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

5h 42m1 stop Dallas/Fort Worth

$595American Airlines

Sat, Sep 12 - Mon, Sep 14

7:30 am - 11:32 amTYS Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong

5h 02m1 stop Dallas/Fort Worth

8:00 am - 1:53 pmMSY New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson

4h 53m1 stop Dallas/Fort Worth

$629American Airlines

Fri, Sep 11 - Mon, Sep 14

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American Airlines flights from Knoxville to Louisiana

Our best American Airlines deals on Knoxville to Louisiana flight tickets

American Airlines

Feb 24

TYS3:00 pmKnoxville McGhee Tyson

7h 35m

1 stop

MSY9:35 pmNew Orleans Louis Armstrong

Feb 27

MSY8:00 amNew Orleans Louis Armstrong

7h 34m

1 stop

TYS4:34 pmKnoxville McGhee Tyson

$287

American Airlines

Jan 22

TYS6:44 pmKnoxville McGhee Tyson

5h 19m

1 stop

MSY11:03 pmNew Orleans Louis Armstrong

Jan 25

MSY3:52 pmNew Orleans Louis Armstrong

6h 19m

1 stop

TYS11:11 pmKnoxville McGhee Tyson

$299

American Airlines

Dec 4

TYS6:07 pmKnoxville McGhee Tyson

7h 01m

1 stop

MSY12:08 amNew Orleans Louis Armstrong

Dec 12

MSY7:43 amNew Orleans Louis Armstrong

5h 22m

1 stop

TYS2:05 pmKnoxville McGhee Tyson

$313

Southwest flights from Knoxville to Louisiana

Our best Southwest deals on Knoxville to Louisiana flight tickets

Southwest

Jan 8

TYS2:40 pmKnoxville McGhee Tyson

8h 10m

2 stops

MSY9:50 pmNew Orleans Louis Armstrong

Jan 11

MSY7:30 amNew Orleans Louis Armstrong

5h 30m

1 stop

TYS2:00 pmKnoxville McGhee Tyson

$304

Southwest

Oct 7

TYS5:15 pmKnoxville McGhee Tyson

5h 55m

1 stop

MSY10:10 pmNew Orleans Louis Armstrong

Oct 13

MSY7:35 amNew Orleans Louis Armstrong

8h 05m

1 stop

TYS4:40 pmKnoxville McGhee Tyson

$310

Southwest

Feb 17

TYS7:00 amKnoxville McGhee Tyson

7h 50m

2 stops

MSY1:50 pmNew Orleans Louis Armstrong

Feb 20

MSY5:30 amNew Orleans Louis Armstrong

7h 25m

1 stop

TYS1:55 pmKnoxville McGhee Tyson

$314

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Tue 2/23

5:20 pm-9:15 pm

1 stop4h 55m

New Orleans Louis Armstrong

Wed 2/24

8:00 am-2:42 pm

1 stop5h 42m

$282

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Thu 10/15

9:28 pm-10:09 pm

1 stop25h 41m

New Orleans Louis Armstrong

Mon 10/19

9:05 pm-6:52 pm

1 stop20h 47m

$285

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Wed 2/24

5:57 pm-11:59 pm

1 stop7h 02m

New Orleans Louis Armstrong

Mon 3/1

8:00 am-2:09 pm

1 stop5h 09m

$287

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Tue 10/13

6:20 am-9:27 am

1 stop4h 07m

New Orleans Louis Armstrong

Sat 10/17

5:41 am-2:07 pm

1 stop7h 26m

$287

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Wed 2/17

12:00 pm-4:05 pm

1 stop5h 05m

New Orleans Louis Armstrong

Sat 2/20

8:00 am-2:42 pm

1 stop5h 42m

$287

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Wed 2/24

3:00 pm-9:35 pm

1 stop7h 35m

New Orleans Louis Armstrong

Sat 2/27

8:00 am-4:34 pm

1 stop7h 34m

$287

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Wed 10/7

5:40 am-8:04 am

1 stop3h 24m

New Orleans Louis Armstrong

Wed 10/14

5:20 am-9:34 am

1 stop3h 14m

$301

Quickest round-trip

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Thu 10/1

5:40 am-8:00 am

1 stop3h 20m

New Orleans Louis Armstrong

Mon 10/5

9:05 am-1:21 pm

1 stop3h 16m

$303

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Fri 1/8

2:40 pm-9:50 pm

2 stops8h 10m

New Orleans Louis Armstrong

Mon 1/11

7:30 am-2:00 pm

1 stop5h 30m

$304

KnoxvilleNew Orleans

TYS Knoxville McGhee Tyson - MSY New Orleans Louis Armstrong

TYSMSY

Knoxville McGhee Tyson

Fri 1/22

2:40 pm-9:50 pm

2 stops8h 10m

New Orleans Louis Armstrong

Mon 1/25

6:00 am-3:45 pm

1 stop8h 45m

$304

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Louisiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Louisiana?

In general, November is the cheapest month to fly from Knoxville to Louisiana. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $313. The month of December is another great option to travel to Louisiana, with average flight prices from Knoxville averaging around $336.

Cheap Knoxville to Louisiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Louisiana

Best Price Found	$118
Fastest flight time	3h 58m
Direct flights	None

The best one-way flight to Louisiana from Knoxville in the past 72 hours is $118. The best round-trip flight deal from Knoxville to Louisiana found on momondo in the last 72 hours is $282.

The fastest flight from Knoxville to Louisiana takes 3h 58m

There are no direct flights from Knoxville to Louisiana. There are no popular flight routes from Knoxville to Louisiana.

Search flight deals

Frequently asked questions about flying from Knoxville to Louisiana

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Louisiana?
Prices for flights from Knoxville McGhee Tyson Airport to Louisiana are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Louisiana?
There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Louisiana as of September 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Louisiana?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Louisiana.
What documentation or ID do you need to fly to Louisiana?
The travel and health documents required for your trip to Louisiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Louisiana

Compare and see reviews for airlines that fly from Knoxville to Louisiana with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $223	Free Cancellation	Rating 7.1 12,046 reviews	Search American Airlines flights
Delta	PriceFrom $268	Free Cancellation	Rating 7.8 8,553 reviews	Search Delta flights
Southwest	PriceFrom $289	Free Cancellation	Rating 8.0 4,195 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Louisiana?

It is quick and easy to find Knoxville to Louisiana flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Louisiana that suits you.

Can I find flights from Knoxville to Louisiana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Louisiana flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Louisiana?

momondo provides multiple filters to help you find the best flight to Louisiana from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Louisiana right now. Can momondo alert me if prices change?

Price alerts on flights to Louisiana from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.