What is the cheapest airline that flies from Knoxville McGhee Tyson to Louisiana?

Southwest, Delta, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Louisiana

What airlines fly to Louisiana?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to Louisiana from Knoxville according to our data. Delta is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Louisiana. Keep in mind that there are 3 different airlines that fly to Louisiana on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Louisiana?

Prices for flights from Knoxville McGhee Tyson Airport to Louisiana are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Louisiana?

There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Louisiana as of April 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Louisiana?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Louisiana.

What documentation or ID do you need to fly to Louisiana?

The travel and health documents required for your trip to Louisiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$101 Cheap Flights from Knoxville to Louisiana in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Louisiana

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:03 pm - 4:18 pm

TYS

MSY

19h 15m

1 stop

4:25 pm - 11:39 pm

MSY

TYS

6h 14m

1 stop

$191Multiple Airlines

Fri, Jun 5 - Mon, Jun 8

12:27 pm - 4:21 pm

TYS

MSY

28h 54m

2 stops

7:00 am - 4:15 pm

MSY

TYS

8h 15m

1 stop

$199Multiple Airlines

Fri, May 29 - Tue, Jun 2

1:15 pm - 10:23 pm

TYS

MSY

10h 08m

1 stop

8:13 pm - 5:30 pm

MSY

TYS

20h 17m

1 stop

$218Multiple Airlines

Fri, May 1 - Sun, May 3

12:37 pm - 4:31 pm

TYS

MSY

4h 54m

1 stop

7:38 pm - 2:58 pm

MSY

TYS

18h 20m

1 stop

$230Multiple Airlines

Sun, May 3 - Mon, May 4

3:40 pm - 10:00 pm

TYS

LFT

7h 20m

1 stop

5:27 pm - 11:56 pm

LFT

TYS

5h 29m

1 stop

$304American Airlines

Thu, May 28 - Wed, Jun 3

3:54 pm - 9:25 pm

TYS

AEX

6h 31m

1 stop

5:09 pm - 11:54 pm

AEX

TYS

5h 45m

1 stop

$308Delta

Wed, Jun 10 - Sun, Jun 14

6:54 pm - 10:37 pm

TYS

AEX

4h 43m

1 stop

10:07 am - 10:56 pm

AEX

TYS

11h 49m

2 stops

$314American Airlines

Fri, May 1 - Tue, May 5

7:33 pm - 10:00 pm

TYS

BTR

3h 27m

1 stop

6:03 am - 11:09 am

BTR

TYS

4h 06m

1 stop

$351Delta

Fri, May 8 - Sun, May 10

3:25 pm - 7:38 pm

TYS

AEX

5h 13m

1 stop

4:05 pm - 9:30 pm

AEX

TYS

4h 25m

1 stop

$388United Airlines

Tue, Aug 18 - Sat, Aug 22

3:25 pm - 7:38 pm

TYS

AEX

5h 13m

1 stop

4:05 pm - 9:30 pm

AEX

TYS

4h 25m

1 stop

$393United Airlines

Tue, Aug 18 - Sat, Aug 22

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American Airlines flights from Knoxville to Louisiana

Our best American Airlines deals on Knoxville to Louisiana flight tickets

American Airlines

May 28

TYS3:40 pmKnoxville McGhee Tyson

7h 20m

1 stop

LFT10:00 pmLafayette Regional

Jun 3

LFT5:27 pmLafayette Regional

5h 29m

1 stop

TYS11:56 pmKnoxville McGhee Tyson

$304

American Airlines

May 27

TYS7:59 pmKnoxville McGhee Tyson

5h 00m

1 stop

MSY11:59 pmNew Orleans Louis Armstrong

May 28

MSY12:17 pmNew Orleans Louis Armstrong

6h 14m

1 stop

TYS7:31 pmKnoxville McGhee Tyson

$308

American Airlines

May 1

TYS6:54 pmKnoxville McGhee Tyson

4h 43m

1 stop

AEX10:37 pmAlexandria

May 5

AEX10:07 amAlexandria

11h 49m

2 stops

TYS10:56 pmKnoxville McGhee Tyson

$314

Delta flights from Knoxville to Louisiana

Our best Delta deals on Knoxville to Louisiana flight tickets

Delta

Jun 10

TYS3:54 pmKnoxville McGhee Tyson

6h 31m

1 stop

AEX9:25 pmAlexandria

Jun 14

AEX5:09 pmAlexandria

5h 45m

1 stop

TYS11:54 pmKnoxville McGhee Tyson

$308

Delta

May 27

TYS5:40 amKnoxville McGhee Tyson

4h 53m

1 stop

MSY9:33 amNew Orleans Louis Armstrong

May 27

MSY7:10 pmNew Orleans Louis Armstrong

3h 51m

1 stop

TYS12:01 amKnoxville McGhee Tyson

$311

Delta

May 11

TYS7:33 pmKnoxville McGhee Tyson

4h 12m

1 stop

MSY10:45 pmNew Orleans Louis Armstrong

May 13

MSY6:20 amNew Orleans Louis Armstrong

3h 49m

1 stop

TYS11:09 amKnoxville McGhee Tyson

$324

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 6/5

10:03 pm-4:18 pm

1 stop19h 15m

New Orleans Louis Armstrong

Mon 6/8

4:25 pm-11:39 pm

1 stop6h 14m

$191

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 5/29

12:27 pm-4:21 pm

2 stops28h 54m

New Orleans Louis Armstrong

Tue 6/2

7:00 am-4:15 pm

1 stop8h 15m

$199

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 5/1

1:15 pm-10:23 pm

1 stop10h 08m

New Orleans Louis Armstrong

Sun 5/3

8:13 pm-5:30 pm

1 stop20h 17m

$218

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 5/3

12:37 pm-4:31 pm

1 stop4h 54m

New Orleans Louis Armstrong

Mon 5/4

7:38 pm-2:58 pm

1 stop18h 20m

$230

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 5/28

3:40 pm-10:00 pm

1 stop7h 20m

Lafayette Regional

Wed 6/3

5:27 pm-11:56 pm

1 stop5h 29m

$304

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

Wed 6/10

3:54 pm-9:25 pm

1 stop6h 31m

Alexandria

Sun 6/14

5:09 pm-11:54 pm

1 stop5h 45m

$308

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

Fri 5/1

6:54 pm-10:37 pm

1 stop4h 43m

Alexandria

Tue 5/5

10:07 am-10:56 pm

2 stops11h 49m

$314

Quickest round-trip

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Fri 5/8

7:33 pm-10:00 pm

1 stop3h 27m

Baton Rouge Ryan

Sun 5/10

6:03 am-11:09 am

1 stop4h 06m

$351

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

Tue 8/18

3:25 pm-7:38 pm

1 stop5h 13m

Alexandria

Sat 8/22

4:05 pm-9:30 pm

1 stop4h 25m

$388

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

Tue 8/18

3:25 pm-7:38 pm

1 stop5h 13m

Alexandria

Sat 8/22

4:05 pm-9:30 pm

1 stop4h 25m

$393

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Louisiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Louisiana?

In general, August is the cheapest month to fly from Knoxville to Louisiana. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $297. The month of November is another great option to travel to Louisiana, with average flight prices from Knoxville averaging around $333.

How far in advance should I book a flight to Louisiana?

You are more likely to see cheaper flights to Louisiana from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Louisiana for around $384 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Louisiana from Knoxville for as low as $248 on momondo.

Can stopping save me money on Knoxville to Louisiana flights?

You could potentially save up to 24% on your flight if you consider stops on a Knoxville to Louisiana flight.

Cheap Knoxville to Louisiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Louisiana

Fastest flight time	3h 27m
Direct flights	None

The fastest flight from Knoxville to Louisiana takes 3h 27m

There are no direct flights from Knoxville to Louisiana. There are no popular flight routes from Knoxville to Louisiana.

Search flight deals

Frequently asked questions about flying from Knoxville to Louisiana

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Louisiana?
Prices for flights from Knoxville McGhee Tyson Airport to Louisiana are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Louisiana?
There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Louisiana as of April 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Louisiana?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Louisiana.
What documentation or ID do you need to fly to Louisiana?
The travel and health documents required for your trip to Louisiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Louisiana

Compare and see reviews for airlines that fly from Knoxville to Louisiana with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 11,621 reviews	Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,422 reviews	Search Delta flights
Southwest	PriceFrom $294	Free Cancellation	Rating 8.0 4,328 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Louisiana?

It is quick and easy to find Knoxville to Louisiana flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Louisiana that suits you.

Can I find flights from Knoxville to Louisiana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Louisiana flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Louisiana?

momondo provides multiple filters to help you find the best flight to Louisiana from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Louisiana right now. Can momondo alert me if prices change?

Price alerts on flights to Louisiana from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.