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Cheap flights from Knoxville to Louisiana from $124

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Louisiana departing on 11/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to Louisiana

Cheap round-trip flights

Frontier Logo
8:17 pm - 5:42 pmTYS-MSY
22h 25m1 stop
Frontier Logo
7:25 pm - 7:32 pmMSY-TYS
23h 07m1 stop
$221Frontier
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Thu, Oct 16 - Thu, Oct 23
Multiple Airlines Logo
4:26 pm - 11:53 pmTYS-MSY
8h 27m1 stop
Multiple Airlines Logo
11:09 am - 12:38 pmMSY-TYS
24h 29m1 stop
$229Multiple Airlines
Find Deal
Wed, Oct 29 - Sat, Nov 1
Delta Logo
1:27 pm - 4:24 pmTYS-BTR
3h 57m1 stop
Delta Logo
2:21 pm - 8:06 pmBTR-TYS
4h 45m1 stop
$249Delta
Find Deal
Sat, Nov 15 - Tue, Nov 18
American Airlines Logo
5:00 am - 9:18 amTYS-MSY
5h 18m1 stop
American Airlines Logo
3:56 pm - 12:23 amMSY-TYS
7h 27m1 stop
$251American Airlines
Find Deal
Tue, Oct 14 - Sat, Oct 18
Delta Logo
5:44 am - 8:00 amTYS-MSY
3h 16m1 stop
Delta Logo
5:20 am - 9:20 amMSY-TYS
3h 00m1 stop
$260Delta
Find Deal
Wed, Oct 15 - Sun, Oct 19
American Airlines Logo
6:00 am - 10:37 amTYS-BTR
5h 37m1 stop
American Airlines Logo
6:36 pm - 11:50 pmBTR-TYS
4h 14m1 stop
$274American Airlines
Find Deal
Sat, Oct 11 - Mon, Oct 20
Southwest Logo
7:25 pm - 10:35 pmTYS-MSY
4h 10m1 stop
Southwest Logo
6:00 am - 12:45 pmMSY-TYS
5h 45m2 stops
$324Southwest
Find Deal
Sun, Mar 15 - Fri, Mar 20
Southwest Logo
6:35 am - 2:20 pmTYS-MSY
8h 45m2 stops
Southwest Logo
6:00 am - 12:45 pmMSY-TYS
5h 45m2 stops
$349Southwest
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Sun, Mar 15 - Fri, Mar 20
United Airlines Logo
7:15 am - 11:10 amTYS-LFT
4h 55m1 stop
United Airlines Logo
5:15 am - 11:43 pmLFT-TYS
17h 28m1 stop
$582United Airlines
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Fri, Oct 10 - Sun, Oct 12
United Airlines Logo
7:15 am - 11:10 amTYS-LFT
4h 55m1 stop
United Airlines Logo
5:15 am - 10:10 amLFT-TYS
27h 55m2 stops
$601United Airlines
Find Deal
Fri, Oct 10 - Sun, Oct 12

Delta flights from Knoxville to Louisiana

Our best Delta deals on Knoxville to Louisiana flight tickets
Delta
Nov 15
TYS1:27 pmKnoxville McGhee Tyson
3h 57m
1 stop
BTR4:24 pmBaton Rouge Ryan
Nov 18
BTR2:21 pmBaton Rouge Ryan
4h 45m
1 stop
TYS8:06 pmKnoxville McGhee Tyson
$249
Find similar
Delta
Oct 15
TYS5:44 amKnoxville McGhee Tyson
3h 16m
1 stop
MSY8:00 amNew Orleans Louis Armstrong
Oct 19
MSY5:20 amNew Orleans Louis Armstrong
3h 00m
1 stop
TYS9:20 amKnoxville McGhee Tyson
$260
Find similar
Delta
Oct 17
TYS5:44 amKnoxville McGhee Tyson
3h 16m
1 stop
MSY8:00 amNew Orleans Louis Armstrong
Oct 19
MSY5:20 amNew Orleans Louis Armstrong
3h 00m
1 stop
TYS9:20 amKnoxville McGhee Tyson
$269
Find similar

American Airlines flights from Knoxville to Louisiana

Our best American Airlines deals on Knoxville to Louisiana flight tickets
American Airlines
Oct 14
TYS5:00 amKnoxville McGhee Tyson
5h 18m
1 stop
MSY9:18 amNew Orleans Louis Armstrong
Oct 18
MSY3:56 pmNew Orleans Louis Armstrong
7h 27m
1 stop
TYS12:23 amKnoxville McGhee Tyson
$251
Find similar
American Airlines
Oct 11
TYS6:00 amKnoxville McGhee Tyson
5h 37m
1 stop
BTR10:37 amBaton Rouge Ryan
Oct 20
BTR6:36 pmBaton Rouge Ryan
4h 14m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
$274
Find similar
American Airlines
Oct 11
TYS6:00 amKnoxville McGhee Tyson
5h 37m
1 stop
BTR10:37 amBaton Rouge Ryan
Oct 20
BTR6:36 pmBaton Rouge Ryan
4h 14m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
$279
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 23, 2025.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 10/16

8:17 pm-5:42 pm

1 stop22h 25m

New Orleans Louis Armstrong

Thu 10/23

7:25 pm-7:32 pm

1 stop23h 07m

$221

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 10/29

4:26 pm-11:53 pm

1 stop8h 27m

New Orleans Louis Armstrong

Sat 11/1

11:09 am-12:38 pm

1 stop24h 29m

$229

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Sat 11/15

1:27 pm-4:24 pm

1 stop3h 57m

Baton Rouge Ryan

Tue 11/18

2:21 pm-8:06 pm

1 stop4h 45m

$249

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 10/14

5:00 am-9:18 am

1 stop5h 18m

New Orleans Louis Armstrong

Sat 10/18

3:56 pm-12:23 am

1 stop7h 27m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 10/15

5:44 am-8:00 am

1 stop3h 16m

New Orleans Louis Armstrong

Sun 10/19

5:20 am-9:20 am

1 stop3h 00m

$260

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Sat 10/11

6:00 am-10:37 am

1 stop5h 37m

Baton Rouge Ryan

Mon 10/20

6:36 pm-11:50 pm

1 stop4h 14m

$274

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 3/15

7:25 pm-10:35 pm

1 stop4h 10m

New Orleans Louis Armstrong

Fri 3/20

6:00 am-12:45 pm

2 stops5h 45m

$324

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 3/15

6:35 am-2:20 pm

2 stops8h 45m

New Orleans Louis Armstrong

Fri 3/20

6:00 am-12:45 pm

2 stops5h 45m

$349

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Fri 10/10

7:15 am-11:10 am

1 stop4h 55m

Lafayette Regional

Sun 10/12

5:15 am-11:43 pm

1 stop17h 28m

$582

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Fri 10/10

7:15 am-11:10 am

1 stop4h 55m

Lafayette Regional

Sun 10/12

5:15 am-10:10 am

2 stops27h 55m

$601

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisiana from

How to get the cheapest flight ticket from Knoxville to Louisiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisiana?

In general, August is the cheapest month to fly from Knoxville to Louisiana. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $293. The month of June is another great option to travel to Louisiana, with average flight prices from Knoxville averaging around $331.

What is the cheapest day to depart on your flight to Louisiana?

According to our data, Saturday is the cheapest day to fly to Louisiana from Knoxville. The lowest ticket price found for a Saturday departure recently was $308. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Louisiana on Thursday is $387.

What is the cheapest time of day to depart on your flight to Louisiana?

The cheapest time of day to fly to Louisiana is in the afternoon when flights can be purchased for as low as $318. In contrast, the most expensive time of day to depart to Louisiana is in the morning when prices are around $363.

How far in advance should I book a flight to Louisiana?

You are more likely to see cheaper flights to Louisiana from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Louisiana for around $369 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Louisiana from Knoxville for as low as $275 on momondo.

Can stopping save me money on Knoxville to Louisiana flights?

You could potentially save up to 29% on your flight if you consider stops on a Knoxville to Louisiana flight.

Cheap Knoxville to Louisiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Louisiana

Direct flights

None
There are no direct flights from Knoxville to Louisiana. There are no popular flight routes from Knoxville to Louisiana.
Search flight deals

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Louisiana?

    Prices for flights from Knoxville McGhee Tyson Airport to Louisiana are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Louisiana?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Louisiana?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Louisiana.

  • What documentation or ID do you need to fly to Louisiana?

    The travel and health documents required for your trip to Louisiana can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisiana. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Louisiana

Compare and see reviews for airlines that fly from Knoxville to Louisiana with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $223Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
American AirlinesPriceFrom $228Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $243Free CancellationRating
7.9
7,974 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Louisiana?

It is quick and easy to find Knoxville to Louisiana flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Louisiana that suits you.

Can I find flights from Knoxville to Louisiana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Louisiana flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Louisiana?

momondo provides multiple filters to help you find the best flight to Louisiana from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Louisiana right now. Can momondo alert me if prices change?

Price alerts on flights to Louisiana from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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