Cheap flights from Knoxville to Harrisburg from $155

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Harrisburg departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Delta Logo
6:59 am - 12:58 pmTYS-MDT
5h 59m1 stop
Delta Logo
6:23 pm - 11:44 pmMDT-TYS
5h 21m1 stop
$229Delta
Find Deal
Sat, Sep 20 - Mon, Sep 22
Delta Logo
1:20 pm - 11:46 pmTYS-MDT
10h 26m2 stops
Delta Logo
6:23 pm - 11:44 pmMDT-TYS
5h 21m1 stop
$234Delta
Find Deal
Sat, Sep 20 - Mon, Sep 22
American Airlines Logo
12:03 pm - 5:38 pmTYS-MDT
5h 35m2 stops
American Airlines Logo
4:45 pm - 11:03 pmMDT-TYS
6h 18m2 stops
$239American Airlines
Find Deal
Wed, Aug 27 - Wed, Sep 3
American Airlines Logo
8:04 pm - 12:18 amTYS-MDT
4h 14m1 stop
American Airlines Logo
7:57 pm - 12:05 amMDT-TYS
4h 08m1 stop
$259American Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9
United Airlines Logo
5:45 am - 9:33 amTYS-MDT
3h 48m1 stop
United Airlines Logo
6:30 am - 1:25 pmMDT-TYS
6h 55m1 stop
$265United Airlines
Find Deal
Fri, Aug 29 - Sun, Aug 31
American Airlines Logo
5:27 pm - 11:56 pmTYS-MDT
6h 29m1 stop
American Airlines Logo
5:00 am - 12:26 pmMDT-TYS
7h 26m1 stop
$289American Airlines
Find Deal
Fri, Aug 29 - Sun, Aug 31
United Airlines Logo
5:45 am - 9:45 amTYS-MDT
4h 00m1 stop
United Airlines Logo
5:48 pm - 10:37 pmMDT-TYS
4h 49m1 stop
$299United Airlines
Find Deal
Fri, Aug 15 - Tue, Aug 19
Delta Logo
6:14 pm - 10:24 pmTYS-MDT
4h 10m1 stop
Delta Logo
6:23 pm - 11:44 pmMDT-TYS
5h 21m1 stop
$309Delta
Find Deal
Wed, Sep 10 - Fri, Sep 12
Delta Logo
1:00 pm - 10:24 pmTYS-MDT
9h 24m2 stops
Delta Logo
6:23 pm - 11:44 pmMDT-TYS
5h 21m1 stop
$314Delta
Find Deal
Wed, Sep 10 - Fri, Sep 12
 Logo
4:31 pm - 4:07 pmTYS-MDT
23h 36m3 stops
 Logo
8:20 pm - 10:07 amMDT-TYS
13h 47m1 stop
Wed, Sep 10 - Fri, Sep 12

American Airlines flights from Knoxville to Harrisburg

Our best American Airlines deals on Knoxville to Harrisburg flight tickets
American Airlines
Aug 27
TYS12:03 pmKnoxville McGhee Tyson
5h 35m
2 stops
MDT5:38 pmHarrisburg
Sep 3
MDT4:45 pmHarrisburg
6h 18m
2 stops
TYS11:03 pmKnoxville McGhee Tyson
American Airlines
Dec 2
TYS8:04 pmKnoxville McGhee Tyson
4h 14m
1 stop
MDT12:18 amHarrisburg
Dec 9
MDT7:57 pmHarrisburg
4h 08m
1 stop
TYS12:05 amKnoxville McGhee Tyson
American Airlines
Aug 29
TYS5:27 pmKnoxville McGhee Tyson
6h 29m
1 stop
MDT11:56 pmHarrisburg
Aug 31
MDT5:00 amHarrisburg
7h 26m
1 stop
TYS12:26 pmKnoxville McGhee Tyson

Delta flights from Knoxville to Harrisburg

Our best Delta deals on Knoxville to Harrisburg flight tickets
Delta
Sep 20
TYS6:59 amKnoxville McGhee Tyson
5h 59m
1 stop
MDT12:58 pmHarrisburg
Sep 22
MDT6:23 pmHarrisburg
5h 21m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Delta
Sep 20
TYS1:20 pmKnoxville McGhee Tyson
10h 26m
2 stops
MDT11:46 pmHarrisburg
Sep 22
MDT6:23 pmHarrisburg
5h 21m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Delta
Sep 10
TYS6:14 pmKnoxville McGhee Tyson
4h 10m
1 stop
MDT10:24 pmHarrisburg
Sep 12
MDT6:23 pmHarrisburg
5h 21m
1 stop
TYS11:44 pmKnoxville McGhee Tyson

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 9/20

6:59 am-12:58 pm

1 stop5h 59m

Harrisburg

Mon 9/22

6:23 pm-11:44 pm

1 stop5h 21m

$229

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 9/20

1:20 pm-11:46 pm

2 stops10h 26m

Harrisburg

Mon 9/22

6:23 pm-11:44 pm

1 stop5h 21m

$234

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 8/27

12:03 pm-5:38 pm

2 stops5h 35m

Harrisburg

Wed 9/3

4:45 pm-11:03 pm

2 stops6h 18m

$239

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Tue 12/2

8:04 pm-12:18 am

1 stop4h 14m

Harrisburg

Tue 12/9

7:57 pm-12:05 am

1 stop4h 08m

$259

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 8/29

5:45 am-9:33 am

1 stop3h 48m

Harrisburg

Sun 8/31

6:30 am-1:25 pm

1 stop6h 55m

$265

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 8/29

5:27 pm-11:56 pm

1 stop6h 29m

Harrisburg

Sun 8/31

5:00 am-12:26 pm

1 stop7h 26m

$289

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 8/15

5:45 am-9:45 am

1 stop4h 00m

Harrisburg

Tue 8/19

5:48 pm-10:37 pm

1 stop4h 49m

$299

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 9/10

6:14 pm-10:24 pm

1 stop4h 10m

Harrisburg

Fri 9/12

6:23 pm-11:44 pm

1 stop5h 21m

$309

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 9/10

1:00 pm-10:24 pm

2 stops9h 24m

Harrisburg

Fri 9/12

6:23 pm-11:44 pm

1 stop5h 21m

$314

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 9/10

4:31 pm-4:07 pm

3 stops23h 36m

Harrisburg

Fri 9/12

8:20 pm-10:07 am

1 stop13h 47m

$331

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Harrisburg from

How to get the cheapest flight ticket from Knoxville to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Harrisburg?

What is the cheapest month to fly to Harrisburg?

The month of March is, on average, the cheapest month to fly to Harrisburg from Knoxville, with most prices found around $269. If you aren’t able to travel to Harrisburg during the month of March, then flying in December is also cheap. Prices for this month can be found on momondo for an average of $307.

What is the cheapest day to depart on your flight to Harrisburg?

The cheapest day to depart from Knoxville to Harrisburg is on a Tuesday. Travelers who choose to depart for Harrisburg on a Tuesday will often find tickets for as low as $278. On the other hand, Sunday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $531.

What is the cheapest time of day to depart on your flight to Harrisburg?

Our data shows that the cheapest Knoxville to Harrisburg flights are usually those with departure times in the afternoon. Our users have found flights to Harrisburg in the afternoon for as low as $305. Try not to purchase tickets in the evening because they tend to be around $398. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Knoxville to Harrisburg

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Harrisburg according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Harrisburg (TYS to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Harrisburg

Best Price Found

$155

Fastest flight time

3h 41m

Direct flights

None

Airports in Harrisburg

1 airport
The best one-way flight to Harrisburg from Knoxville in the past 72 hours is $155. The best round-trip flight deal from Knoxville to Harrisburg found on momondo in the last 72 hours is $229.
The fastest flight from Knoxville to Harrisburg takes 3h 41m
There are no direct flights from Knoxville to Harrisburg. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Harrisburg Airport.
There is 1 airport near Harrisburg: Harrisburg (MDT)

  • How far is Knoxville McGhee Tyson to Harrisburg by plane?

    The straight-line distance from Knoxville McGhee Tyson to Harrisburg is 484.3 mi. 3h 41m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.

  • What documentation or ID do you need to fly to Harrisburg Airport?

    The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Harrisburg?


Best airlines flying from Knoxville to Harrisburg

Compare and see reviews for airlines that fly from Knoxville to Harrisburg with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $233Free CancellationRating
8.0
7,981 reviews
Search Delta flights
United AirlinesPriceFrom $288Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Hershey
Carlisle
Mechanicsburg
Camp Hill
Hummelstown

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Harrisburg?

Finding the right flight to Harrisburg from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Harrisburg quick and easy, saving you time and money.

Can I find flights from Knoxville to Harrisburg with flexible booking policies on momondo?

All flight searches from Knoxville to Harrisburg on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Harrisburg?

Once all potential Knoxville to Harrisburg flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Harrisburg right now. Can momondo alert me if prices change?

Price alerts on flights to Harrisburg from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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1 adult
Tue 8/5
Tue 8/12

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