Which layover airport has the shortest travel time from Knoxville to Harrisburg?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 07m.

Which layover airport has the shortest connection time from Knoxville to Harrisburg?

Charlotte (CLT) has the shortest average layover time for this route: 0h 51m.

Which layover airport offers the lowest fares from Knoxville to Harrisburg?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $513.

What airlines fly to Harrisburg?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Harrisburg from Knoxville according to our data. American Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Harrisburg. Keep in mind that there are 4 different airlines that fly to Harrisburg on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Harrisburg?

Delta, Allegiant Air, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Harrisburg

Which airport is the most popular layover for flights between Knoxville and Harrisburg?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

As of September 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.

What documentation or ID do you need to fly to Harrisburg Airport?

The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$269 Cheap Flights from Knoxville to Harrisburg in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Harrisburg

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:52 pm - 1:19 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

22h 27m1 stop Orlando Sanford Intl

8:51 pm - 9:44 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

24h 53m1 stop Orlando Sanford Intl

$293Allegiant Air

Tue, Oct 20 - Sun, Oct 25

7:58 pm - 12:24 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 26m1 stop Charlotte Douglas

12:18 pm - 5:35 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 17m1 stop Philadelphia

$299American Airlines

Sat, Oct 24 - Sun, Oct 25

7:25 pm - 11:29 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 04m1 stop Washington, D.C. Dulles Intl

6:15 am - 10:37 amMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 22m1 stop Washington, D.C. Dulles Intl

$299United Airlines

Wed, Oct 14 - Sun, Oct 18

11:49 am - 4:16 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 27m1 stop Detroit Metropolitan Wayne County

12:20 pm - 6:22 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 02m1 stop Detroit Metropolitan Wayne County

$299Delta

Fri, Dec 4 - Mon, Dec 7

7:58 pm - 12:24 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 26m1 stop Charlotte Douglas

12:18 pm - 5:35 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 17m1 stop Philadelphia

$299American Airlines

Thu, Oct 22 - Sun, Oct 25

6:56 am - 11:40 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 44m1 stop Charlotte Douglas

2:32 pm - 8:18 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 46m1 stop Philadelphia

$299American Airlines

Wed, Oct 14 - Sat, Oct 17

6:00 am - 1:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 59m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:15 am - 10:37 amMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 22m1 stop Washington, D.C. Dulles Intl

$304United Airlines

Wed, Oct 14 - Sun, Oct 18

5:40 am - 11:38 amTYS Knoxville McGhee Tyson-MDT Harrisburg

5h 58m1 stop Atlanta Hartsfield-Jackson

6:06 pm - 11:59 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 53m1 stop Atlanta Hartsfield-Jackson

$319Delta

Sat, Oct 24 - Mon, Oct 26

10:26 am - 5:08 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

6h 42m1 stop Atlanta Hartsfield-Jackson

6:00 am - 11:18 amMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 18m1 stop Atlanta Hartsfield-Jackson

$323Delta

Thu, Oct 1 - Sun, Oct 4

6:00 am - 1:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 59m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

2:08 pm - 8:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 41m1 stop Chicago O'Hare Intl

$324United Airlines

Wed, Oct 14 - Sat, Oct 17

Cheap last minute flights

Enter your travel dates to find the best prices.

6:15 am - 10:17 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 02m1 stop Charlotte Douglas

11:17 am - 5:31 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 14m1 stop Charlotte Douglas

$379American Airlines

Wed, Sep 16 - Sat, Sep 19

6:00 am - 1:39 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 39m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

2:52 pm - 8:24 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 32m1 stop Washington, D.C. Dulles Intl

$416United Airlines

Wed, Sep 16 - Sat, Sep 19

6:00 am - 1:39 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 39m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

2:52 pm - 10:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

7h 57m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$422United Airlines

Wed, Sep 16 - Sat, Sep 19

6:00 am - 1:39 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 39m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

10:30 am - 10:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

12h 19m3 stops Washington, D.C. Dulles Intl Newark Chicago O'Hare Intl

$601United Airlines

Wed, Sep 16 - Sat, Sep 19

4:46 pm - 9:15 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 29m1 stop Philadelphia

6:00 am - 10:50 amMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 50m1 stop Chicago O'Hare Intl

$779American Airlines

Mon, Sep 14 - Wed, Sep 16

7:20 pm - 11:30 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 10m1 stop Washington, D.C. Dulles Intl

7:59 pm - 11:59 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 00m1 stop Washington, D.C. Dulles Intl

$779United Airlines

Mon, Sep 14 - Wed, Sep 16

5:45 am - 9:37 amTYS Knoxville McGhee Tyson-MDT Harrisburg

3h 52m1 stop Washington, D.C. Dulles Intl

10:30 am - 10:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

12h 19m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$784United Airlines

Mon, Sep 14 - Wed, Sep 16

5:45 am - 9:37 amTYS Knoxville McGhee Tyson-MDT Harrisburg

3h 52m1 stop Washington, D.C. Dulles Intl

10:30 am - 10:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

12h 19m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$784United Airlines

Mon, Sep 14 - Wed, Sep 16

6:00 am - 11:30 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

17h 30m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

10:30 am - 10:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

12h 19m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$1,002United Airlines

Mon, Sep 14 - Wed, Sep 16

1:53 pm - 11:30 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

9h 37m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:30 am - 2:37 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

8h 07m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$2,198United Airlines

Mon, Sep 14 - Wed, Sep 16

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United Airlines flights from Knoxville to Harrisburg

Our best United Airlines deals on Knoxville to Harrisburg flight tickets

United Airlines

Oct 14

TYS7:25 pmKnoxville McGhee Tyson

4h 04m

1 stop

MDT11:29 pmHarrisburg

Oct 18

MDT6:15 amHarrisburg

4h 22m

1 stop

TYS10:37 amKnoxville McGhee Tyson

$299

United Airlines

Oct 14

TYS6:00 amKnoxville McGhee Tyson

7h 59m

2 stops

MDT1:59 pmHarrisburg

Oct 18

MDT6:15 amHarrisburg

4h 22m

1 stop

TYS10:37 amKnoxville McGhee Tyson

$304

United Airlines

Oct 24

TYS6:00 amKnoxville McGhee Tyson

7h 59m

2 stops

MDT1:59 pmHarrisburg

Oct 26

MDT8:13 pmHarrisburg

3h 46m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

$324

Delta flights from Knoxville to Harrisburg

Our best Delta deals on Knoxville to Harrisburg flight tickets

Delta

Oct 24

TYS5:40 amKnoxville McGhee Tyson

5h 58m

1 stop

MDT11:38 amHarrisburg

Oct 26

MDT6:06 pmHarrisburg

5h 53m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

$319

Delta

Oct 1

TYS10:26 amKnoxville McGhee Tyson

6h 42m

1 stop

MDT5:08 pmHarrisburg

Oct 4

MDT6:00 amHarrisburg

5h 18m

1 stop

TYS11:18 amKnoxville McGhee Tyson

$323

Delta

Oct 1

TYS10:26 amKnoxville McGhee Tyson

6h 42m

1 stop

MDT5:08 pmHarrisburg

Oct 4

MDT6:00 amHarrisburg

5h 18m

1 stop

TYS11:18 amKnoxville McGhee Tyson

$348

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Tue 10/20

2:52 pm-1:19 pm

1 stop22h 27m

Harrisburg

Sun 10/25

8:51 pm-9:44 pm

1 stop24h 53m

$293

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Sat 10/24

7:58 pm-12:24 am

1 stop4h 26m

Harrisburg

Sun 10/25

12:18 pm-5:35 pm

1 stop5h 17m

$299

Quickest round-trip

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Wed 10/14

7:25 pm-11:29 pm

1 stop4h 04m

Harrisburg

Sun 10/18

6:15 am-10:37 am

1 stop4h 22m

$299

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Fri 12/4

11:49 am-4:16 pm

1 stop4h 27m

Harrisburg

Mon 12/7

12:20 pm-6:22 pm

1 stop6h 02m

$299

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Thu 10/22

7:58 pm-12:24 am

1 stop4h 26m

Harrisburg

Sun 10/25

12:18 pm-5:35 pm

1 stop5h 17m

$299

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Wed 10/14

6:56 am-11:40 am

1 stop4h 44m

Harrisburg

Sat 10/17

2:32 pm-8:18 pm

1 stop5h 46m

$299

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Wed 10/14

6:00 am-1:59 pm

2 stops7h 59m

Harrisburg

Sun 10/18

6:15 am-10:37 am

1 stop4h 22m

$304

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Sat 10/24

5:40 am-11:38 am

1 stop5h 58m

Harrisburg

Mon 10/26

6:06 pm-11:59 pm

1 stop5h 53m

$319

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Thu 10/1

10:26 am-5:08 pm

1 stop6h 42m

Harrisburg

Sun 10/4

6:00 am-11:18 am

1 stop5h 18m

$323

KnoxvilleHarrisburg

TYS Knoxville McGhee Tyson - MDT Harrisburg

TYSMDT

Knoxville McGhee Tyson

Wed 10/14

6:00 am-1:59 pm

2 stops7h 59m

Harrisburg

Sat 10/17

2:08 pm-8:49 pm

1 stop6h 41m

$324

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Knoxville and Harrisburg?

Prices are currently low for flights on this route.

Typical prices usually range from $611 to $1,007.
The lowest price recently found on this route was $293.

What is the cheapest month to fly to Harrisburg?

The month of December is, on average, the cheapest month to fly to Harrisburg from Knoxville, with most prices found around $321. If you aren’t able to travel to Harrisburg during the month of December, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $369.

When to book flights from Knoxville to Harrisburg

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Harrisburg according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Harrisburg (TYS to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Harrisburg

Best Price Found	$269
Fastest flight time	3h 33m
Direct flights	None

The best one-way flight to Harrisburg from Knoxville in the past 72 hours is $269. The best round-trip flight deal from Knoxville to Harrisburg found on momondo in the last 72 hours is $293.

The fastest flight from Knoxville to Harrisburg takes 3h 33m

There are no direct flights from Knoxville to Harrisburg. There are no popular flight routes from Knoxville to Harrisburg.

Search flight deals

Frequently asked questions about flying from Knoxville to Harrisburg

How far is Knoxville McGhee Tyson to Harrisburg by plane?
The straight-line distance from Knoxville McGhee Tyson to Harrisburg is 484.3 mi. 3h 33m is a normal flight duration for this route.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
As of September 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.
What documentation or ID do you need to fly to Harrisburg Airport?
The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Harrisburg?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Harrisburg is American Airlines (54% of total bookings). The next most popular airline is United Airlines (46%).

Best airlines flying from Knoxville to Harrisburg

Compare and see reviews for airlines that fly from Knoxville to Harrisburg with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $282	Free Cancellation	Rating 7.1 12,049 reviews		Search American Airlines flights
United Airlines	PriceFrom $309	Free Cancellation	Rating 7.4 10,201 reviews		Search United Airlines flights

Hershey

Carlisle

Mechanicsburg

Camp Hill

Hummelstown

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Why should I use momondo to find a flight deal from Knoxville to Harrisburg?

Finding the right flight to Harrisburg from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Harrisburg quick and easy, saving you time and money.

Can I find flights from Knoxville to Harrisburg with flexible booking policies on momondo?

All flight searches from Knoxville to Harrisburg on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Harrisburg?

Once all potential Knoxville to Harrisburg flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Harrisburg right now. Can momondo alert me if prices change?

Price alerts on flights to Harrisburg from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.