Which layover airport offers the lowest fares from Knoxville to Harrisburg?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $513.

What airlines fly to Harrisburg?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Harrisburg from Knoxville according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Harrisburg. Keep in mind that there are 4 different airlines that fly to Harrisburg on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Knoxville to Harrisburg?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 07m.

Which layover airport has the shortest connection time from Knoxville to Harrisburg?

Charlotte (CLT) has the shortest average layover time for this route: 0h 51m.

Which airport is the most popular layover for flights between Knoxville and Harrisburg?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Harrisburg?

Allegiant Air, American Airlines, and Delta are the most popular carriers operating from Knoxville McGhee Tyson to Harrisburg

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

As of May 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.

What documentation or ID do you need to fly to Harrisburg Airport?

The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$141 Cheap Flights from Knoxville to Harrisburg in 2026

Q: What is the typical price of a round-trip flight between Knoxville and Harrisburg?

Prices are currently low for flights on this route. Typical prices usually range from $597 to $530. The lowest price recently found on this route was $289.

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Find the cheapest flights from Knoxville to Harrisburg

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:00 am - 11:37 am

TYS

MDT

6h 37m

1 stop

5:43 pm - 11:47 pm

MDT

TYS

6h 04m

1 stop

$289American Airlines

Tue, Jun 16 - Tue, Jun 23

6:00 am - 1:50 pm

TYS

MDT

7h 50m

2 stops

7:59 pm - 11:54 pm

MDT

TYS

3h 55m

1 stop

$294United Airlines

Thu, Jul 2 - Mon, Jul 6

7:15 am - 5:08 pm

TYS

MDT

9h 53m

1 stop

8:58 pm - 9:15 pm

MDT

TYS

24h 17m

1 stop

$306Allegiant Air

Thu, Jul 9 - Sun, Jul 12

6:00 am - 1:50 pm

TYS

MDT

7h 50m

2 stops

7:59 pm - 11:54 pm

MDT

TYS

3h 55m

1 stop

$359United Airlines

Thu, Jul 9 - Sun, Jul 12

9:28 pm - 8:23 am

TYS

MDT

10h 55m

1 stop

8:39 pm - 11:14 am

MDT

TYS

14h 35m

1 stop

$361Allegiant Air

Thu, Oct 15 - Sun, Oct 18

8:10 am - 12:18 pm

TYS

MDT

4h 08m

1 stop

11:17 am - 3:22 pm

MDT

TYS

4h 05m

1 stop

$382American Airlines

Tue, Sep 8 - Tue, Sep 22

1:54 pm - 9:29 pm

TYS

MDT

7h 35m

1 stop

6:15 am - 10:42 am

MDT

TYS

4h 27m

1 stop

$389United Airlines

Wed, Jun 10 - Sun, Jun 14

5:45 am - 9:40 am

TYS

MDT

3h 55m

1 stop

7:59 pm - 11:54 pm

MDT

TYS

3h 55m

1 stop

$404United Airlines

Thu, Jul 9 - Sun, Jul 12

2:00 pm - 7:30 pm

TYS

MDT

5h 30m

1 stop

6:00 am - 1:18 pm

MDT

TYS

7h 18m

2 stops

$408United Airlines

Sat, Nov 7 - Wed, Nov 11

6:00 am - 2:18 pm

TYS

MDT

8h 18m

1 stop

8:50 pm - 11:38 pm

MDT

TYS

26h 48m

1 stop

$411Allegiant Air

Sat, Jun 13 - Thu, Jun 18

United Airlines flights from Knoxville to Harrisburg

Our best United Airlines deals on Knoxville to Harrisburg flight tickets

United Airlines

Jul 2

TYS6:00 amKnoxville McGhee Tyson

7h 50m

2 stops

MDT1:50 pmHarrisburg

Jul 6

MDT7:59 pmHarrisburg

3h 55m

1 stop

TYS11:54 pmKnoxville McGhee Tyson

$294

United Airlines

Jul 9

TYS6:00 amKnoxville McGhee Tyson

7h 50m

2 stops

MDT1:50 pmHarrisburg

Jul 12

MDT7:59 pmHarrisburg

3h 55m

1 stop

TYS11:54 pmKnoxville McGhee Tyson

$359

United Airlines

May 29

TYS7:19 pmKnoxville McGhee Tyson

4h 11m

1 stop

MDT11:30 pmHarrisburg

May 31

MDT7:59 pmHarrisburg

3h 55m

1 stop

TYS11:54 pmKnoxville McGhee Tyson

$378

American Airlines flights from Knoxville to Harrisburg

Our best American Airlines deals on Knoxville to Harrisburg flight tickets

American Airlines

Jun 16

TYS5:00 amKnoxville McGhee Tyson

6h 37m

1 stop

MDT11:37 amHarrisburg

Jun 23

MDT5:43 pmHarrisburg

6h 04m

1 stop

TYS11:47 pmKnoxville McGhee Tyson

$289

American Airlines

Jun 5

TYS7:03 pmKnoxville McGhee Tyson

4h 05m

1 stop

MDT11:08 pmHarrisburg

Jun 14

MDT7:08 pmHarrisburg

4h 45m

1 stop

TYS11:53 pmKnoxville McGhee Tyson

$359

American Airlines

Jun 5

TYS1:00 pmKnoxville McGhee Tyson

6h 00m

1 stop

MDT7:00 pmHarrisburg

Jun 8

MDT7:08 pmHarrisburg

4h 45m

1 stop

TYS11:53 pmKnoxville McGhee Tyson

$379

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Tue 6/16

5:00 am-11:37 am

1 stop6h 37m

Harrisburg

Tue 6/23

5:43 pm-11:47 pm

1 stop6h 04m

$289

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 7/2

6:00 am-1:50 pm

2 stops7h 50m

Harrisburg

Mon 7/6

7:59 pm-11:54 pm

1 stop3h 55m

$294

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 7/9

7:15 am-5:08 pm

1 stop9h 53m

Harrisburg

Sun 7/12

8:58 pm-9:15 pm

1 stop24h 17m

$306

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 7/9

6:00 am-1:50 pm

2 stops7h 50m

Harrisburg

Sun 7/12

7:59 pm-11:54 pm

1 stop3h 55m

$359

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 10/15

9:28 pm-8:23 am

1 stop10h 55m

Harrisburg

Sun 10/18

8:39 pm-11:14 am

1 stop14h 35m

$361

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Tue 9/8

8:10 am-12:18 pm

1 stop4h 08m

Harrisburg

Tue 9/22

11:17 am-3:22 pm

1 stop4h 05m

$382

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 6/10

1:54 pm-9:29 pm

1 stop7h 35m

Harrisburg

Sun 6/14

6:15 am-10:42 am

1 stop4h 27m

$389

Quickest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 7/9

5:45 am-9:40 am

1 stop3h 55m

Harrisburg

Sun 7/12

7:59 pm-11:54 pm

1 stop3h 55m

$404

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 11/7

2:00 pm-7:30 pm

1 stop5h 30m

Harrisburg

Wed 11/11

6:00 am-1:18 pm

2 stops7h 18m

$408

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 6/13

6:00 am-2:18 pm

1 stop8h 18m

Harrisburg

Thu 6/18

8:50 pm-11:38 pm

1 stop26h 48m

$411

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Knoxville and Harrisburg?

What is the cheapest month to fly to Harrisburg?

The month of December is, on average, the cheapest month to fly to Harrisburg from Knoxville, with most prices found around $321. If you aren’t able to travel to Harrisburg during the month of December, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $339.

When to book flights from Knoxville to Harrisburg

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Harrisburg according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Harrisburg (TYS to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Harrisburg

Fastest flight time	3h 52m
Direct flights	None

The fastest flight from Knoxville to Harrisburg takes 3h 52m

There are no direct flights from Knoxville to Harrisburg. There are no popular flight routes from Knoxville to Harrisburg.

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Frequently asked questions about flying from Knoxville to Harrisburg

How far is Knoxville McGhee Tyson to Harrisburg by plane?
The straight-line distance from Knoxville McGhee Tyson to Harrisburg is 484.3 mi. 3h 52m is a normal flight duration for this route.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
As of May 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.
What documentation or ID do you need to fly to Harrisburg Airport?
The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Harrisburg?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Harrisburg is American Airlines (55% of total bookings). The next most popular airline is United Airlines (45%).

Best airlines flying from Knoxville to Harrisburg

Compare and see reviews for airlines that fly from Knoxville to Harrisburg with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 11,639 reviews		Search American Airlines flights
United Airlines	PriceFrom $308	Free Cancellation	Rating 7.4 9,751 reviews		Search United Airlines flights

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Hummelstown

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Harrisburg?

Finding the right flight to Harrisburg from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Harrisburg quick and easy, saving you time and money.

Can I find flights from Knoxville to Harrisburg with flexible booking policies on momondo?

All flight searches from Knoxville to Harrisburg on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Harrisburg?

Once all potential Knoxville to Harrisburg flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Harrisburg right now. Can momondo alert me if prices change?

Price alerts on flights to Harrisburg from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.