Which layover airport has the shortest connection time from Knoxville to Harrisburg?

Charlotte (CLT) has the shortest average layover time for this route: 0h 51m.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Harrisburg?

Allegiant Air and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Harrisburg

What airlines fly to Harrisburg?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Harrisburg from Knoxville according to our data. American Airlines is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Harrisburg. Keep in mind that there are 4 different airlines that fly to Harrisburg on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Knoxville and Harrisburg?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Knoxville to Harrisburg?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $513.

Which layover airport has the shortest travel time from Knoxville to Harrisburg?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 07m.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

As of July 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.

What documentation or ID do you need to fly to Harrisburg Airport?

The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$156 Cheap Flights from Knoxville to Harrisburg in 2026

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Find the cheapest flights from Knoxville to Harrisburg

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:57 am - 11:45 am

TYS

MDT

4h 48m

1 stop

6:15 am - 10:43 am

MDT

TYS

4h 28m

1 stop

$289American Airlines

Wed, Aug 5 - Wed, Aug 12

7:00 am - 2:03 pm

TYS

MDT

7h 03m

2 stops

7:59 pm - 11:59 pm

MDT

TYS

4h 00m

1 stop

$294United Airlines

Thu, Aug 20 - Sun, Aug 23

7:41 pm - 11:43 pm

TYS

MDT

4h 02m

1 stop

6:24 pm - 11:52 pm

MDT

TYS

5h 28m

1 stop

$304Delta

Fri, Aug 28 - Mon, Aug 31

7:25 pm - 11:43 pm

TYS

MDT

4h 18m

1 stop

2:56 pm - 8:08 pm

MDT

TYS

5h 12m

1 stop

$313Delta

Fri, Oct 23 - Mon, Oct 26

7:00 am - 1:32 pm

TYS

MDT

6h 32m

1 stop

2:17 pm - 8:53 pm

MDT

TYS

6h 36m

1 stop

$359United Airlines

Sat, Aug 29 - Tue, Sep 1

7:00 am - 2:03 pm

TYS

MDT

7h 03m

2 stops

2:17 pm - 8:53 pm

MDT

TYS

6h 36m

1 stop

$364United Airlines

Sat, Aug 29 - Tue, Sep 1

12:57 pm - 11:03 am

TYS

MDT

22h 06m

2 stops

11:03 am - 7:57 pm

MDT

TYS

8h 54m

1 stop

$371Allegiant Air

Fri, Oct 23 - Mon, Oct 26

7:20 pm - 11:30 pm

TYS

MDT

4h 10m

1 stop

2:17 pm - 8:53 pm

MDT

TYS

6h 36m

1 stop

$377United Airlines

Mon, Aug 17 - Thu, Aug 20

7:20 pm - 11:30 pm

TYS

MDT

4h 10m

1 stop

10:57 am - 8:53 pm

MDT

TYS

9h 56m

2 stops

$382United Airlines

Mon, Aug 17 - Thu, Aug 20

1:54 pm - 11:30 pm

TYS

MDT

9h 36m

2 stops

7:59 pm - 11:59 pm

MDT

TYS

4h 00m

1 stop

$413United Airlines

Wed, Aug 5 - Wed, Aug 12

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Delta flights from Knoxville to Harrisburg

Our best Delta deals on Knoxville to Harrisburg flight tickets

Delta

Aug 28

TYS7:41 pmKnoxville McGhee Tyson

4h 02m

1 stop

MDT11:43 pmHarrisburg

Aug 31

MDT6:24 pmHarrisburg

5h 28m

1 stop

TYS11:52 pmKnoxville McGhee Tyson

$304

Delta

Oct 23

TYS7:25 pmKnoxville McGhee Tyson

4h 18m

1 stop

MDT11:43 pmHarrisburg

Oct 26

MDT2:56 pmHarrisburg

5h 12m

1 stop

TYS8:08 pmKnoxville McGhee Tyson

$313

Delta

Jul 24

TYS7:49 pmKnoxville McGhee Tyson

4h 04m

1 stop

MDT11:53 pmHarrisburg

Jul 27

MDT6:22 pmHarrisburg

5h 30m

1 stop

TYS11:52 pmKnoxville McGhee Tyson

$339

Allegiant Air flights from Knoxville to Harrisburg

Our best Allegiant Air deals on Knoxville to Harrisburg flight tickets

Allegiant Air

Oct 23

TYS9:41 pmKnoxville McGhee Tyson

13h 22m

1 stop

MDT11:03 amHarrisburg

Oct 26

MDT11:03 amHarrisburg

8h 54m

1 stop

TYS7:57 pmKnoxville McGhee Tyson

$326

Allegiant Air

Oct 23

TYS12:57 pmKnoxville McGhee Tyson

22h 06m

2 stops

MDT11:03 amHarrisburg

Oct 26

MDT11:03 amHarrisburg

8h 54m

1 stop

TYS7:57 pmKnoxville McGhee Tyson

$371

Allegiant Air

Jul 19

TYS6:54 pmKnoxville McGhee Tyson

14h 31m

1 stop

MDT9:25 amHarrisburg

Jul 24

MDT9:08 pmHarrisburg

25h 49m

1 stop

TYS10:57 pmKnoxville McGhee Tyson

$510

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 8/5

6:57 am-11:45 am

1 stop4h 48m

Harrisburg

Wed 8/12

6:15 am-10:43 am

1 stop4h 28m

$289

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 8/20

7:00 am-2:03 pm

2 stops7h 03m

Harrisburg

Sun 8/23

7:59 pm-11:59 pm

1 stop4h 00m

$294

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 8/28

7:41 pm-11:43 pm

1 stop4h 02m

Harrisburg

Mon 8/31

6:24 pm-11:52 pm

1 stop5h 28m

$304

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 10/23

7:25 pm-11:43 pm

1 stop4h 18m

Harrisburg

Mon 10/26

2:56 pm-8:08 pm

1 stop5h 12m

$313

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 8/29

7:00 am-1:32 pm

1 stop6h 32m

Harrisburg

Tue 9/1

2:17 pm-8:53 pm

1 stop6h 36m

$359

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 8/29

7:00 am-2:03 pm

2 stops7h 03m

Harrisburg

Tue 9/1

2:17 pm-8:53 pm

1 stop6h 36m

$364

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 10/23

12:57 pm-11:03 am

2 stops22h 06m

Harrisburg

Mon 10/26

11:03 am-7:57 pm

1 stop8h 54m

$371

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Mon 8/17

7:20 pm-11:30 pm

1 stop4h 10m

Harrisburg

Thu 8/20

2:17 pm-8:53 pm

1 stop6h 36m

$377

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Mon 8/17

7:20 pm-11:30 pm

1 stop4h 10m

Harrisburg

Thu 8/20

10:57 am-8:53 pm

2 stops9h 56m

$382

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 8/5

1:54 pm-11:30 pm

2 stops9h 36m

Harrisburg

Wed 8/12

7:59 pm-11:59 pm

1 stop4h 00m

$413

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Harrisburg?

The month of December is, on average, the cheapest month to fly to Harrisburg from Knoxville, with most prices found around $321. If you aren’t able to travel to Harrisburg during the month of December, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $369.

When to book flights from Knoxville to Harrisburg

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Harrisburg according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Harrisburg (TYS to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Harrisburg

Fastest flight time	3h 55m
Direct flights	None

The fastest flight from Knoxville to Harrisburg takes 3h 55m

There are no direct flights from Knoxville to Harrisburg. There are no popular flight routes from Knoxville to Harrisburg.

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Frequently asked questions about flying from Knoxville to Harrisburg

How far is Knoxville McGhee Tyson to Harrisburg by plane?
The straight-line distance from Knoxville McGhee Tyson to Harrisburg is 484.3 mi. 3h 55m is a normal flight duration for this route.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
As of July 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.
What documentation or ID do you need to fly to Harrisburg Airport?
The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Harrisburg?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Harrisburg is American Airlines (55% of total bookings). The next most popular airline is United Airlines (45%).

Best airlines flying from Knoxville to Harrisburg

Compare and see reviews for airlines that fly from Knoxville to Harrisburg with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 11,806 reviews		Search American Airlines flights
United Airlines	PriceFrom $309	Free Cancellation	Rating 7.4 9,988 reviews		Search United Airlines flights

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Mechanicsburg

Camp Hill

Hummelstown

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Harrisburg?

Finding the right flight to Harrisburg from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Harrisburg quick and easy, saving you time and money.

Can I find flights from Knoxville to Harrisburg with flexible booking policies on momondo?

All flight searches from Knoxville to Harrisburg on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Harrisburg?

Once all potential Knoxville to Harrisburg flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Harrisburg right now. Can momondo alert me if prices change?

Price alerts on flights to Harrisburg from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.