Which layover airport has the shortest travel time from Knoxville to Harrisburg?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 07m.

Which layover airport offers the lowest fares from Knoxville to Harrisburg?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $513.

What airlines fly to Harrisburg?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Harrisburg from Knoxville according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Harrisburg. Keep in mind that there are 4 different airlines that fly to Harrisburg on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Knoxville and Harrisburg?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from Knoxville to Harrisburg?

Charlotte (CLT) has the shortest average layover time for this route: 0h 51m.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Harrisburg?

Allegiant Air, Delta, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Harrisburg

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

As of April 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.

What documentation or ID do you need to fly to Harrisburg Airport?

The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$134 Cheap Flights from Knoxville to Harrisburg in 2026

Q: What is the typical price of a round-trip flight between Knoxville and Harrisburg?

Prices are currently low for flights on this route. Typical prices usually range from $649 to $560. The lowest price recently found on this route was $247.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Harrisburg

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:25 pm - 5:26 pm

TYS

MDT

20h 01m

1 stop

7:20 pm - 12:53 pm

MDT

TYS

17h 33m

1 stop

$247Allegiant Air

Thu, Apr 30 - Sun, May 3

9:40 pm - 5:26 pm

TYS

MDT

19h 46m

1 stop

10:34 am - 7:55 pm

MDT

TYS

9h 21m

1 stop

$260Allegiant Air

Thu, May 14 - Sun, May 17

6:03 pm - 8:44 am

TYS

MDT

14h 41m

1 stop

7:58 pm - 9:55 pm

MDT

TYS

25h 57m

1 stop

$270Allegiant Air

Thu, May 28 - Sat, Jun 6

9:40 pm - 5:26 pm

TYS

MDT

19h 46m

1 stop

5:57 pm - 6:34 pm

MDT

TYS

24h 37m

1 stop

$278Allegiant Air

Thu, May 14 - Thu, May 21

9:40 pm - 5:26 pm

TYS

MDT

19h 46m

1 stop

5:57 pm - 11:37 pm

MDT

TYS

29h 40m

2 stops

$290Multiple Airlines

Thu, May 14 - Thu, May 21

6:03 pm - 8:44 am

TYS

MDT

14h 41m

1 stop

7:58 pm - 9:55 pm

MDT

TYS

25h 57m

1 stop

$300Allegiant Air

Thu, May 28 - Sat, Jun 6

6:13 am - 11:45 am

TYS

MDT

5h 32m

1 stop

12:11 pm - 6:12 pm

MDT

TYS

6h 01m

1 stop

$309American Airlines

Thu, Sep 3 - Sun, Sep 6

9:40 pm - 4:00 pm

TYS

MDT

18h 20m

2 stops

10:34 am - 7:55 pm

MDT

TYS

9h 21m

1 stop

$320Multiple Airlines

Thu, May 14 - Sun, May 17

7:20 pm - 11:40 pm

TYS

MDT

4h 20m

1 stop

12:25 pm - 6:17 pm

MDT

TYS

5h 52m

1 stop

$333Delta

Fri, Sep 4 - Sat, Sep 5

6:13 am - 11:45 am

TYS

MDT

5h 32m

1 stop

6:15 am - 10:48 am

MDT

TYS

4h 33m

1 stop

$343American Airlines

Thu, Sep 3 - Mon, Sep 7

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Allegiant Air flights from Knoxville to Harrisburg

Our best Allegiant Air deals on Knoxville to Harrisburg flight tickets

Allegiant Air

Apr 30

TYS9:25 pmKnoxville McGhee Tyson

20h 01m

1 stop

MDT5:26 pmHarrisburg

May 3

MDT7:20 pmHarrisburg

17h 33m

1 stop

TYS12:53 pmKnoxville McGhee Tyson

$247

Allegiant Air

Apr 23

TYS9:32 pmKnoxville McGhee Tyson

19h 54m

1 stop

MDT5:26 pmHarrisburg

Apr 27

MDT9:20 amHarrisburg

24h 20m

1 stop

TYS9:40 amKnoxville McGhee Tyson

$248

Allegiant Air

May 14

TYS9:40 pmKnoxville McGhee Tyson

19h 46m

1 stop

MDT5:26 pmHarrisburg

May 17

MDT10:34 amHarrisburg

9h 21m

1 stop

TYS7:55 pmKnoxville McGhee Tyson

$260

United Airlines flights from Knoxville to Harrisburg

Our best United Airlines deals on Knoxville to Harrisburg flight tickets

United Airlines

Jul 2

TYS7:19 pmKnoxville McGhee Tyson

4h 11m

1 stop

MDT11:30 pmHarrisburg

Jul 5

MDT7:59 pmHarrisburg

3h 55m

1 stop

TYS11:54 pmKnoxville McGhee Tyson

$379

United Airlines

Sep 3

TYS5:45 amKnoxville McGhee Tyson

3h 51m

1 stop

MDT9:36 amHarrisburg

Sep 6

MDT6:15 amHarrisburg

6h 58m

2 stops

TYS1:13 pmKnoxville McGhee Tyson

$384

United Airlines

Apr 28

TYS7:00 amKnoxville McGhee Tyson

6h 55m

2 stops

MDT1:55 pmHarrisburg

May 2

MDT10:40 amHarrisburg

10h 05m

2 stops

TYS8:45 pmKnoxville McGhee Tyson

$399

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 4/30

9:25 pm-5:26 pm

1 stop20h 01m

Harrisburg

Sun 5/3

7:20 pm-12:53 pm

1 stop17h 33m

$247

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 5/14

9:40 pm-5:26 pm

1 stop19h 46m

Harrisburg

Sun 5/17

10:34 am-7:55 pm

1 stop9h 21m

$260

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 5/28

6:03 pm-8:44 am

1 stop14h 41m

Harrisburg

Sat 6/6

7:58 pm-9:55 pm

1 stop25h 57m

$270

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 5/14

9:40 pm-5:26 pm

1 stop19h 46m

Harrisburg

Thu 5/21

5:57 pm-6:34 pm

1 stop24h 37m

$278

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 5/14

9:40 pm-5:26 pm

1 stop19h 46m

Harrisburg

Thu 5/21

5:57 pm-11:37 pm

2 stops29h 40m

$290

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 5/28

6:03 pm-8:44 am

1 stop14h 41m

Harrisburg

Sat 6/6

7:58 pm-9:55 pm

1 stop25h 57m

$300

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 9/3

6:13 am-11:45 am

1 stop5h 32m

Harrisburg

Sun 9/6

12:11 pm-6:12 pm

1 stop6h 01m

$309

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 5/14

9:40 pm-4:00 pm

2 stops18h 20m

Harrisburg

Sun 5/17

10:34 am-7:55 pm

1 stop9h 21m

$320

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 9/4

7:20 pm-11:40 pm

1 stop4h 20m

Harrisburg

Sat 9/5

12:25 pm-6:17 pm

1 stop5h 52m

$333

Quickest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 9/3

6:13 am-11:45 am

1 stop5h 32m

Harrisburg

Mon 9/7

6:15 am-10:48 am

1 stop4h 33m

$343

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Knoxville and Harrisburg?

What is the cheapest month to fly to Harrisburg?

The month of December is, on average, the cheapest month to fly to Harrisburg from Knoxville, with most prices found around $321. If you aren’t able to travel to Harrisburg during the month of December, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $339.

When to book flights from Knoxville to Harrisburg

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Harrisburg according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Harrisburg (TYS to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Harrisburg

Fastest flight time	4h 11m
Direct flights	None

The fastest flight from Knoxville to Harrisburg takes 4h 11m

There are no direct flights from Knoxville to Harrisburg. There are no popular flight routes from Knoxville to Harrisburg.

Search flight deals

Frequently asked questions about flying from Knoxville to Harrisburg

How far is Knoxville McGhee Tyson to Harrisburg by plane?
The straight-line distance from Knoxville McGhee Tyson to Harrisburg is 484.3 mi. 4h 11m is a normal flight duration for this route.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
As of April 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.
What documentation or ID do you need to fly to Harrisburg Airport?
The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Harrisburg?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Harrisburg is American Airlines (44% of total bookings). The next most popular airlines are United Airlines (37%) and Delta (19%).

Best airlines flying from Knoxville to Harrisburg

Compare and see reviews for airlines that fly from Knoxville to Harrisburg with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.1 11,584 reviews	Search American Airlines flights
Delta	PriceFrom $233	Free Cancellation	Rating 7.9 8,409 reviews	Search Delta flights
United Airlines	PriceFrom $308	Free Cancellation	Rating 7.4 9,594 reviews	Search United Airlines flights

Hershey

Carlisle

Mechanicsburg

Camp Hill

Hummelstown

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Harrisburg?

Finding the right flight to Harrisburg from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Harrisburg quick and easy, saving you time and money.

Can I find flights from Knoxville to Harrisburg with flexible booking policies on momondo?

All flight searches from Knoxville to Harrisburg on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Harrisburg?

Once all potential Knoxville to Harrisburg flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Harrisburg right now. Can momondo alert me if prices change?

Price alerts on flights to Harrisburg from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.