Which layover airport has the shortest connection time from Knoxville to Harrisburg?

Charlotte (CLT) has the shortest average layover time for this route: 0h 51m.

Which layover airport offers the lowest fares from Knoxville to Harrisburg?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $513.

Which airport is the most popular layover for flights between Knoxville and Harrisburg?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Knoxville to Harrisburg?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 07m.

What airlines fly to Harrisburg?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Harrisburg from Knoxville according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Harrisburg. Keep in mind that there are 3 different airlines that fly to Harrisburg on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

As of December 2025, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.

What documentation or ID do you need to fly to Harrisburg Airport?

The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$229 Cheap Flights from Knoxville to Harrisburg in 2025/26

Q: What is the typical price of a round-trip flight between Knoxville and Harrisburg?

Prices are currently low for flights on this route. Typical prices usually range from $304 to $400. The lowest price recently found on this route was $229.

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5:15 pm - 11:50 pm

TYS

MDT

6h 35m1 stop

4:49 pm - 11:21 pm

MDT

TYS

6h 32m1 stop

$229American Airlines

Thu, Jan 8 - Sat, Jan 10

5:42 am - 9:10 am

TYS

MDT

3h 28m1 stop

5:09 am - 10:50 am

MDT

TYS

5h 41m1 stop

$244American Airlines

Thu, Dec 25 - Thu, Jan 1

6:45 am - 1:54 pm

TYS

MDT

7h 09m2 stops

6:15 am - 10:56 am

MDT

TYS

4h 41m1 stop

$264United Airlines

Thu, Dec 25 - Thu, Jan 1

9:30 am - 1:51 pm

TYS

MDT

4h 21m1 stop

3:10 pm - 8:52 pm

MDT

TYS

5h 42m1 stop

$289United Airlines

Thu, Jan 8 - Sun, Jan 11

6:45 am - 1:51 pm

TYS

MDT

7h 06m2 stops

6:30 am - 1:24 pm

MDT

TYS

6h 54m1 stop

$294United Airlines

Thu, Jan 8 - Sun, Jan 11

6:28 pm - 10:17 pm

TYS

MDT

3h 49m1 stop

1:52 pm - 8:43 pm

MDT

TYS

6h 51m1 stop

$299American Airlines

Sat, Dec 13 - Sat, Dec 20

7:49 pm - 11:28 am

TYS

MDT

15h 39m1 stop

7:28 pm - 10:12 pm

MDT

TYS

26h 44m1 stop

$305Allegiant Air

Fri, Dec 12 - Sun, Dec 14

5:40 am - 10:48 am

TYS

MDT

5h 08m1 stop

6:00 am - 11:47 am

MDT

TYS

5h 47m1 stop

$309Delta

Thu, Dec 11 - Sun, Dec 14

7:38 am - 2:29 pm

TYS

MDT

6h 51m1 stop

11:56 am - 5:58 pm

MDT

TYS

6h 02m1 stop

$319American Airlines

Thu, Dec 11 - Sat, Dec 13

6:45 am - 1:54 pm

TYS

MDT

7h 09m2 stops

6:15 am - 10:56 am

MDT

TYS

4h 41m1 stop

$324United Airlines

Thu, Dec 25 - Thu, Jan 1

Allegiant Air flights from Knoxville to Harrisburg

Our best Allegiant Air deals on Knoxville to Harrisburg flight tickets

Allegiant Air

Dec 12

TYS7:49 pmKnoxville McGhee Tyson

15h 39m

1 stop

MDT11:28 amHarrisburg

Dec 14

MDT7:28 pmHarrisburg

26h 44m

1 stop

TYS10:12 pmKnoxville McGhee Tyson

$305

Find similar

Allegiant Air

Dec 29

TYS6:30 amKnoxville McGhee Tyson

26h 20m

1 stop

MDT8:50 amHarrisburg

Jan 3

MDT7:09 pmHarrisburg

27h 03m

1 stop

TYS10:12 pmKnoxville McGhee Tyson

$347

Find similar

Allegiant Air

Dec 10

TYS6:09 pmKnoxville McGhee Tyson

24h 29m

1 stop

MDT6:38 pmHarrisburg

Dec 12

MDT11:35 amHarrisburg

10h 37m

1 stop

TYS10:12 pmKnoxville McGhee Tyson

$607

Find similar

American Airlines flights from Knoxville to Harrisburg

Our best American Airlines deals on Knoxville to Harrisburg flight tickets

American Airlines

Jan 8

TYS5:15 pmKnoxville McGhee Tyson

6h 35m

1 stop

MDT11:50 pmHarrisburg

Jan 10

MDT4:49 pmHarrisburg

6h 32m

1 stop

TYS11:21 pmKnoxville McGhee Tyson

$229

Find similar

American Airlines

Dec 25

TYS5:42 amKnoxville McGhee Tyson

3h 28m

1 stop

MDT9:10 amHarrisburg

Jan 1

MDT5:09 amHarrisburg

5h 41m

1 stop

TYS10:50 amKnoxville McGhee Tyson

$244

Find similar

American Airlines

Dec 13

TYS6:28 pmKnoxville McGhee Tyson

3h 49m

1 stop

MDT10:17 pmHarrisburg

Dec 20

MDT1:52 pmHarrisburg

6h 51m

1 stop

TYS8:43 pmKnoxville McGhee Tyson

$299

Find similar

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/8

5:15 pm-11:50 pm

1 stop6h 35m

Harrisburg

Sat 1/10

4:49 pm-11:21 pm

1 stop6h 32m

$229

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 12/25

5:42 am-9:10 am

1 stop3h 28m

Harrisburg

Thu 1/1

5:09 am-10:50 am

1 stop5h 41m

$244

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 12/25

6:45 am-1:54 pm

2 stops7h 09m

Harrisburg

Thu 1/1

6:15 am-10:56 am

1 stop4h 41m

$264

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/8

9:30 am-1:51 pm

1 stop4h 21m

Harrisburg

Sun 1/11

3:10 pm-8:52 pm

1 stop5h 42m

$289

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/8

6:45 am-1:51 pm

2 stops7h 06m

Harrisburg

Sun 1/11

6:30 am-1:24 pm

1 stop6h 54m

$294

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 12/13

6:28 pm-10:17 pm

1 stop3h 49m

Harrisburg

Sat 12/20

1:52 pm-8:43 pm

1 stop6h 51m

$299

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 12/12

7:49 pm-11:28 am

1 stop15h 39m

Harrisburg

Sun 12/14

7:28 pm-10:12 pm

1 stop26h 44m

$305

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 12/11

5:40 am-10:48 am

1 stop5h 08m

Harrisburg

Sun 12/14

6:00 am-11:47 am

1 stop5h 47m

$309

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 12/11

7:38 am-2:29 pm

1 stop6h 51m

Harrisburg

Sat 12/13

11:56 am-5:58 pm

1 stop6h 02m

$319

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 12/25

6:45 am-1:54 pm

2 stops7h 09m

Harrisburg

Thu 1/1

6:15 am-10:56 am

1 stop4h 41m

$324

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Knoxville and Harrisburg?

What is the cheapest month to fly to Harrisburg?

The month of March is, on average, the cheapest month to fly to Harrisburg from Knoxville, with most prices found around $269. If you aren’t able to travel to Harrisburg during the month of March, then flying in December is also cheap. Prices for this month can be found on momondo for an average of $332.

What is the cheapest day to depart on your flight to Harrisburg?

The cheapest day to depart from Knoxville to Harrisburg is on a Tuesday. Travelers who choose to depart for Harrisburg on a Tuesday will often find tickets for as low as $278. On the other hand, Sunday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $531.

What is the cheapest time of day to depart on your flight to Harrisburg?

Our data shows that the cheapest Knoxville to Harrisburg flights are usually those with departure times in the afternoon. Our users have found flights to Harrisburg in the afternoon for as low as $305. Try not to purchase tickets in the evening because they tend to be around $398. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Knoxville to Harrisburg

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Harrisburg according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Harrisburg (TYS to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Harrisburg

Fastest flight time	4h 04m
Direct flights	None

The fastest flight from Knoxville to Harrisburg takes 4h 04m

There are no direct flights from Knoxville to Harrisburg. There are no popular flight routes from Knoxville to Harrisburg.

Search flight deals

How far is Knoxville McGhee Tyson to Harrisburg by plane?
The straight-line distance from Knoxville McGhee Tyson to Harrisburg is 484.3 mi. 3h 28m is a normal flight duration for this route.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?
As of December 2025, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Harrisburg Airport.
What documentation or ID do you need to fly to Harrisburg Airport?
The required travel and health documents for your Harrisburg Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Harrisburg Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Harrisburg?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Harrisburg is American Airlines (52% of total bookings). The next most popular airlines are United Airlines (28%) and Delta (20%).

Best airlines flying from Knoxville to Harrisburg

Compare and see reviews for airlines that fly from Knoxville to Harrisburg with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.2 11,042 reviews	Search American Airlines flights
Delta	PriceFrom $233	Free Cancellation	Rating 7.9 8,013 reviews	Search Delta flights
United Airlines	PriceFrom $321	Free Cancellation	Rating 7.4 9,076 reviews	Search United Airlines flights

Hershey

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Mechanicsburg

Camp Hill

Hummelstown

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Harrisburg?

Finding the right flight to Harrisburg from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Harrisburg quick and easy, saving you time and money.

Can I find flights from Knoxville to Harrisburg with flexible booking policies on momondo?

All flight searches from Knoxville to Harrisburg on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Harrisburg?

Once all potential Knoxville to Harrisburg flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Harrisburg right now. Can momondo alert me if prices change?

Price alerts on flights to Harrisburg from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Harrisburg trip

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Cheap flights from Knoxville to Harrisburg from $229

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Harrisburg departing on 1/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Allegiant Air flights from Knoxville to Harrisburg

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How to get the cheapest flight ticket from Knoxville to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Harrisburg?

What is the cheapest month to fly to Harrisburg?

What is the cheapest day to depart on your flight to Harrisburg?

What is the cheapest time of day to depart on your flight to Harrisburg?

What airlines fly to Harrisburg?

Which airport is the most popular layover for flights between Knoxville and Harrisburg?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Knoxville to Harrisburg?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $513.

Which layover airport has the shortest travel time from Knoxville to Harrisburg?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 07m.

Which layover airport has the shortest connection time from Knoxville to Harrisburg?

Charlotte (CLT) has the shortest average layover time for this route: 0h 51m.

When to book flights from Knoxville to Harrisburg

Cheap Knoxville to Harrisburg (TYS to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Harrisburg

Fastest flight time

Direct flights

How far is Knoxville McGhee Tyson to Harrisburg by plane?

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Harrisburg Airport?

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Harrisburg Airport?

What documentation or ID do you need to fly to Harrisburg Airport?

What is the most popular airline from Knoxville to Harrisburg?

Best airlines flying from Knoxville to Harrisburg

Compare and see reviews for airlines that fly from Knoxville to Harrisburg with momondo

Traveling to a place near Harrisburg?

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Harrisburg?

Can I find flights from Knoxville to Harrisburg with flexible booking policies on momondo?

How can momondo help me find flights from Knoxville to Harrisburg?

I’m not ready to book a flight from Knoxville to Harrisburg right now. Can momondo alert me if prices change?

An easier way to manage your Harrisburg trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Pennsylvania