Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Key West to San Diego from $183

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to San Diego departing on 10/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Key West to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:01 pm - 8:19 am
EYW
-
SAN
23h 18m
2 stops
Multiple Airlines Logo
12:37 pm - 11:19 am
SAN
-
EYW
19h 42m
1 stop
$370Multiple Airlines
Thu, Sep 24 - Sun, Sep 27
Multiple Airlines Logo
10:04 am - 8:19 am
EYW
-
SAN
25h 15m
2 stops
Multiple Airlines Logo
12:37 pm - 11:19 am
SAN
-
EYW
19h 42m
1 stop
$379Multiple Airlines
Wed, Sep 23 - Sun, Sep 27
Multiple Airlines Logo
8:58 am - 11:59 pm
EYW
-
SAN
18h 01m
2 stops
Multiple Airlines Logo
12:37 pm - 11:19 am
SAN
-
EYW
19h 42m
1 stop
$394Multiple Airlines
Fri, Sep 25 - Sun, Sep 27
Delta Logo
7:40 am - 12:25 pm
EYW
-
SAN
7h 45m
1 stop
Delta Logo
10:25 pm - 10:47 am
SAN
-
EYW
9h 22m
1 stop
$411Delta
Tue, Sep 29 - Sat, Oct 3
Multiple Airlines Logo
12:05 pm - 3:43 pm
EYW
-
SAN
30h 38m
2 stops
Multiple Airlines Logo
12:24 pm - 4:13 pm
SAN
-
EYW
24h 49m
1 stop
$415Multiple Airlines
Sun, Aug 16 - Thu, Aug 20
Multiple Airlines Logo
12:59 pm - 3:41 pm
EYW
-
SAN
29h 42m
2 stops
Multiple Airlines Logo
12:37 pm - 11:19 am
SAN
-
EYW
19h 42m
1 stop
$417Multiple Airlines
Mon, Sep 21 - Sun, Sep 27
Delta Logo
2:00 pm - 9:20 pm
EYW
-
SAN
10h 20m
1 stop
Delta Logo
9:45 pm - 10:47 am
SAN
-
EYW
10h 02m
1 stop
$420Delta
Tue, Sep 22 - Mon, Sep 28
Multiple Airlines Logo
10:04 am - 9:02 am
EYW
-
SAN
25h 58m
3 stops
Multiple Airlines Logo
12:37 pm - 11:19 am
SAN
-
EYW
19h 42m
1 stop
$426Multiple Airlines
Wed, Sep 23 - Sun, Sep 27
Delta Logo
6:15 pm - 11:00 pm
EYW
-
SAN
7h 45m
1 stop
Delta Logo
6:15 am - 5:20 pm
SAN
-
EYW
8h 05m
1 stop
$445Delta
Wed, Aug 5 - Sun, Aug 9
Delta Logo
2:00 pm - 7:27 pm
EYW
-
SAN
8h 27m
1 stop
Delta Logo
8:00 am - 8:01 pm
SAN
-
EYW
9h 01m
1 stop
$455Delta
Wed, Sep 23 - Sat, Sep 26

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Key West to San Diego

Our best American Airlines deals on Key West to San Diego flight tickets
American Airlines
Oct 6
EYW2:15 pmKey West
10h 22m
1 stop
SAN9:37 pmSan Diego
Oct 10
SAN10:27 pmSan Diego
10h 41m
1 stop
EYW12:08 pmKey West
$473
American Airlines
Oct 3
EYW2:15 pmKey West
8h 02m
1 stop
SAN7:17 pmSan Diego
Oct 7
SAN6:20 amSan Diego
7h 34m
1 stop
EYW4:54 pmKey West
$478
American Airlines
Jul 22
EYW1:01 pmKey West
8h 49m
1 stop
SAN6:50 pmSan Diego
Jul 26
SAN10:28 pmSan Diego
10h 46m
1 stop
EYW12:14 pmKey West
$501

Delta flights from Key West to San Diego

Our best Delta deals on Key West to San Diego flight tickets
Delta
Sep 29
EYW7:40 amKey West
7h 45m
1 stop
SAN12:25 pmSan Diego
Oct 3
SAN10:25 pmSan Diego
9h 22m
1 stop
EYW10:47 amKey West
$411
Delta
Sep 22
EYW2:00 pmKey West
10h 20m
1 stop
SAN9:20 pmSan Diego
Sep 28
SAN9:45 pmSan Diego
10h 02m
1 stop
EYW10:47 amKey West
$420
Delta
Aug 5
EYW6:15 pmKey West
7h 45m
1 stop
SAN11:00 pmSan Diego
Aug 9
SAN6:15 amSan Diego
8h 05m
1 stop
EYW5:20 pmKey West
$445

momondo Fare Finder

 
Customize your flight search to find flights from Key West to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from Key West to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Thu 9/24

12:01 pm-8:19 am

2 stops23h 18m

San Diego

Sun 9/27

12:37 pm-11:19 am

1 stop19h 42m

$370

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Wed 9/23

10:04 am-8:19 am

2 stops25h 15m

San Diego

Sun 9/27

12:37 pm-11:19 am

1 stop19h 42m

$379

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Fri 9/25

8:58 am-11:59 pm

2 stops18h 01m

San Diego

Sun 9/27

12:37 pm-11:19 am

1 stop19h 42m

$394

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 9/29

7:40 am-12:25 pm

1 stop7h 45m

San Diego

Sat 10/3

10:25 pm-10:47 am

1 stop9h 22m

$411

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Sun 8/16

12:05 pm-3:43 pm

2 stops30h 38m

San Diego

Thu 8/20

12:24 pm-4:13 pm

1 stop24h 49m

$415

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Mon 9/21

12:59 pm-3:41 pm

2 stops29h 42m

San Diego

Sun 9/27

12:37 pm-11:19 am

1 stop19h 42m

$417

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 9/22

2:00 pm-9:20 pm

1 stop10h 20m

San Diego

Mon 9/28

9:45 pm-10:47 am

1 stop10h 02m

$420

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Wed 9/23

10:04 am-9:02 am

3 stops25h 58m

San Diego

Sun 9/27

12:37 pm-11:19 am

1 stop19h 42m

$426
Quickest round-trip

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Wed 8/5

6:15 pm-11:00 pm

1 stop7h 45m

San Diego

Sun 8/9

6:15 am-5:20 pm

1 stop8h 05m

$445

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Wed 9/23

2:00 pm-7:27 pm

1 stop8h 27m

San Diego

Sat 9/26

8:00 am-8:01 pm

1 stop9h 01m

$455

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Key West to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Key West to San Diego?

United Airlines and Delta are the most popular carriers operating from Key West to San Diego

When to book flights from Key West to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to San Diego (EYW to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to San Diego

Fastest flight time

7h 45m

Direct flights

None
The fastest flight from Key West to San Diego takes 7h 45m
There are no direct flights from Key West to San Diego. There are no popular flight routes from Key West to San Diego.
Search flight deals

Frequently asked questions about flying from Key West to San Diego

  • How far is Key West to San Diego by plane?

    Key West and San Diego are 2204.3 mi apart from one another. Flights usually cover this in 7h 45m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Key West Airport to San Diego Airport?

    Prices for flights from Key West Airport to San Diego Airport were last updated today.

  • How old do you have to be to fly from Key West Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
National City
La Mesa
Poway
San Ysidro
Imperial Beach
Borrego Springs
Santee
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Key West to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Key West.

Can I find flights from Key West to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Key West to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Key West to San Diego?

momondo helps you find the best flight between Key West and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Key West to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Key West to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 8/11
Tue 8/18
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States