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Cheap flights from Key West to San Diego from $206

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to San Diego departing on 7/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Key West to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:21 pm - 7:20 pm
EYW
-
SAN
7h 59m
1 stop
American Airlines Logo
10:45 pm - 1:08 pm
SAN
-
EYW
11h 23m
2 stops
$404American Airlines
Tue, Aug 4 - Tue, Aug 11
American Airlines Logo
4:21 pm - 11:26 pm
EYW
-
SAN
10h 05m
1 stop
American Airlines Logo
10:28 pm - 12:14 pm
SAN
-
EYW
10h 46m
1 stop
$449American Airlines
Fri, Jul 3 - Sat, Jul 11
American Airlines Logo
4:17 pm - 11:48 pm
EYW
-
SAN
10h 31m
1 stop
American Airlines Logo
10:45 pm - 1:14 pm
SAN
-
EYW
11h 29m
2 stops
$474American Airlines
Tue, Jun 30 - Sat, Jul 4
Delta Logo
6:15 pm - 11:00 pm
EYW
-
SAN
7h 45m
1 stop
Delta Logo
10:30 pm - 10:50 am
SAN
-
EYW
9h 20m
1 stop
$482Delta
Wed, Aug 5 - Sun, Aug 9
American Airlines Logo
10:16 am - 6:54 pm
EYW
-
SAN
11h 38m
2 stops
American Airlines Logo
7:00 am - 6:44 pm
SAN
-
EYW
8h 44m
1 stop
$487American Airlines
Wed, Aug 5 - Sun, Aug 9
Multiple Airlines Logo
10:56 am - 8:48 am
EYW
-
SAN
24h 52m
2 stops
Multiple Airlines Logo
12:09 pm - 10:27 am
SAN
-
EYW
19h 18m
1 stop
$488Multiple Airlines
Sun, Jun 28 - Sun, Jul 5
American Airlines Logo
11:28 am - 6:50 pm
EYW
-
SAN
10h 22m
2 stops
American Airlines Logo
10:45 pm - 1:08 pm
SAN
-
EYW
11h 23m
2 stops
$492American Airlines
Tue, Aug 4 - Tue, Aug 11
Multiple Airlines Logo
1:14 pm - 8:51 am
EYW
-
SAN
22h 37m
2 stops
Multiple Airlines Logo
12:09 pm - 10:27 am
SAN
-
EYW
19h 18m
1 stop
$499Multiple Airlines
Tue, Jun 30 - Sun, Jul 5
Multiple Airlines Logo
10:31 am - 9:09 am
EYW
-
SAN
25h 38m
2 stops
Multiple Airlines Logo
12:09 pm - 10:27 am
SAN
-
EYW
19h 18m
1 stop
$514Multiple Airlines
Mon, Jun 29 - Sun, Jul 5
Multiple Airlines Logo
11:07 am - 12:09 pm
EYW
-
SAN
28h 02m
1 stop
Multiple Airlines Logo
9:37 am - 10:05 am
SAN
-
EYW
21h 28m
2 stops
$517Multiple Airlines
Mon, Jun 29 - Sat, Jul 4

American Airlines flights from Key West to San Diego

Our best American Airlines deals on Key West to San Diego flight tickets
American Airlines
Aug 4
EYW2:21 pmKey West
7h 59m
1 stop
SAN7:20 pmSan Diego
Aug 11
SAN10:45 pmSan Diego
11h 23m
2 stops
EYW1:08 pmKey West
$404
American Airlines
Jul 3
EYW4:21 pmKey West
10h 05m
1 stop
SAN11:26 pmSan Diego
Jul 11
SAN10:28 pmSan Diego
10h 46m
1 stop
EYW12:14 pmKey West
$449
American Airlines
Jun 30
EYW4:17 pmKey West
10h 31m
1 stop
SAN11:48 pmSan Diego
Jul 4
SAN10:45 pmSan Diego
11h 29m
2 stops
EYW1:14 pmKey West
$474

Delta flights from Key West to San Diego

Our best Delta deals on Key West to San Diego flight tickets
Delta
Aug 5
EYW6:15 pmKey West
7h 45m
1 stop
SAN11:00 pmSan Diego
Aug 9
SAN10:30 pmSan Diego
9h 20m
1 stop
EYW10:50 amKey West
$482
Delta
Jun 30
EYW7:50 amKey West
8h 31m
1 stop
SAN1:21 pmSan Diego
Jul 6
SAN10:30 pmSan Diego
9h 30m
1 stop
EYW11:00 amKey West
$527
Delta
Jul 3
EYW6:24 pmKey West
17h 59m
2 stops
SAN9:23 amSan Diego
Jul 4
SAN10:30 pmSan Diego
9h 23m
1 stop
EYW10:53 amKey West
$534

momondo Fare Finder

 
Customize your flight search to find flights from Key West to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Key West to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 8/4

2:21 pm-7:20 pm

1 stop7h 59m

San Diego

Tue 8/11

10:45 pm-1:08 pm

2 stops11h 23m

$404

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Fri 7/3

4:21 pm-11:26 pm

1 stop10h 05m

San Diego

Sat 7/11

10:28 pm-12:14 pm

1 stop10h 46m

$449

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 6/30

4:17 pm-11:48 pm

1 stop10h 31m

San Diego

Sat 7/4

10:45 pm-1:14 pm

2 stops11h 29m

$474
Quickest round-trip

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Wed 8/5

6:15 pm-11:00 pm

1 stop7h 45m

San Diego

Sun 8/9

10:30 pm-10:50 am

1 stop9h 20m

$482

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Wed 8/5

10:16 am-6:54 pm

2 stops11h 38m

San Diego

Sun 8/9

7:00 am-6:44 pm

1 stop8h 44m

$487

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Sun 6/28

10:56 am-8:48 am

2 stops24h 52m

San Diego

Sun 7/5

12:09 pm-10:27 am

1 stop19h 18m

$488

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 8/4

11:28 am-6:50 pm

2 stops10h 22m

San Diego

Tue 8/11

10:45 pm-1:08 pm

2 stops11h 23m

$492

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 6/30

1:14 pm-8:51 am

2 stops22h 37m

San Diego

Sun 7/5

12:09 pm-10:27 am

1 stop19h 18m

$499

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Mon 6/29

10:31 am-9:09 am

2 stops25h 38m

San Diego

Sun 7/5

12:09 pm-10:27 am

1 stop19h 18m

$514

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Mon 6/29

11:07 am-12:09 pm

1 stop28h 02m

San Diego

Sat 7/4

9:37 am-10:05 am

2 stops21h 28m

$517

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Key West to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Key West to San Diego?

United Airlines is the most popular carrier operating from Key West to San Diego

When to book flights from Key West to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to San Diego (EYW to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to San Diego

Fastest flight time

7h 45m

Direct flights

None
The fastest flight from Key West to San Diego takes 7h 45m
There are no direct flights from Key West to San Diego. There are no popular flight routes from Key West to San Diego.
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Frequently asked questions about flying from Key West to San Diego

  • How far is Key West to San Diego by plane?

    Key West and San Diego are 2204.3 mi apart from one another. Flights usually cover this in 7h 45m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Key West Airport to San Diego Airport?

    Prices for flights from Key West Airport to San Diego Airport were last updated today.

  • How old do you have to be to fly from Key West Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Imperial Beach
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Key West to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Key West.

Can I find flights from Key West to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Key West to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Key West to San Diego?

momondo helps you find the best flight between Key West and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Key West to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Key West to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

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