Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Key West to San Diego from $238

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to San Diego departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Key West to San Diego (EYW-SAN)

Cheap round-trip flights

Delta Logo
2:00 pm - 6:10 pmEYW-SAN
7h 10m1 stop
Delta Logo
8:00 am - 8:07 pmSAN-EYW
9h 07m1 stop
$309Delta
Find Deal
jue., sep. 11 - lun., sep. 15
American Airlines Logo
1:59 pm - 9:48 pmEYW-SAN
10h 49m2 stops
American Airlines Logo
9:19 pm - 11:13 amSAN-EYW
10h 54m1 stop
$314American Airlines
Find Deal
jue., sep. 11 - lun., sep. 15
American Airlines Logo
11:25 am - 8:16 pmEYW-SAN
11h 51m2 stops
American Airlines Logo
10:32 pm - 10:54 amSAN-EYW
9h 22m2 stops
$319American Airlines
Find Deal
jue., sep. 11 - lun., sep. 15
American Airlines Logo
4:26 pm - 10:22 pmEYW-SAN
8h 56m1 stop
American Airlines Logo
6:15 am - 7:29 pmSAN-EYW
10h 14m2 stops
$379American Airlines
Find Deal
mié., nov. 5 - jue., nov. 13
American Airlines Logo
1:45 pm - 10:20 pmEYW-SAN
11h 35m2 stops
American Airlines Logo
6:15 am - 7:29 pmSAN-EYW
10h 14m2 stops
$384American Airlines
Find Deal
mié., nov. 5 - jue., nov. 13
American Airlines Logo
2:39 pm - 8:20 pmEYW-SAN
8h 41m1 stop
American Airlines Logo
10:35 pm - 11:08 amSAN-EYW
9h 33m1 stop
$446American Airlines
Find Deal
mié., nov. 5 - jue., nov. 13
Delta Logo
7:00 am - 1:05 pmEYW-SAN
9h 05m1 stop
Delta Logo
10:40 pm - 10:59 amSAN-EYW
9h 19m1 stop
$567Delta
Find Deal
lun., nov. 24 - lun., nov. 24
Logo
8:47 am - 7:29 amEYW-SAN
25h 42m3 stops
Logo
11:59 am - 11:52 amSAN-EYW
20h 53m2 stops
$575
Find Deal
vie., sep. 12 - dom., sep. 14
United Airlines Logo
3:50 pm - 3:01 pmEYW-SAN
26h 11m2 stops
United Airlines Logo
4:11 pm - 2:01 pmSAN-EYW
18h 50m3 stops
$598United Airlines
Find Deal
jue., sep. 11 - lun., sep. 15
United Airlines Logo
3:05 pm - 9:14 amEYW-SAN
21h 09m2 stops
United Airlines Logo
5:55 pm - 3:19 pmSAN-EYW
18h 24m3 stops
$716United Airlines
Find Deal
mié., nov. 5 - jue., nov. 13

American Airlines flights from Key West to San Diego

Our best American Airlines deals on Key West to San Diego flight tickets
American Airlines
Sep 11
EYW1:59 pmKey West
10h 49m
2 stops
SAN9:48 pmSan Diego
Sep 15
SAN9:19 pmSan Diego
10h 54m
1 stop
EYW11:13 amKey West
$314
Find similar
American Airlines
Sep 11
EYW11:25 amKey West
11h 51m
2 stops
SAN8:16 pmSan Diego
Sep 15
SAN10:32 pmSan Diego
9h 22m
2 stops
EYW10:54 amKey West
$319
Find similar
American Airlines
Nov 5
EYW4:26 pmKey West
8h 56m
1 stop
SAN10:22 pmSan Diego
Nov 13
SAN6:15 amSan Diego
10h 14m
2 stops
EYW7:29 pmKey West
$379
Find similar

Delta flights from Key West to San Diego

Our best Delta deals on Key West to San Diego flight tickets
Delta
Sep 11
EYW2:00 pmKey West
7h 10m
1 stop
SAN6:10 pmSan Diego
Sep 15
SAN8:00 amSan Diego
9h 07m
1 stop
EYW8:07 pmKey West
$309
Find similar
Delta
Nov 24
EYW7:00 amKey West
9h 05m
1 stop
SAN1:05 pmSan Diego
Nov 24
SAN10:40 pmSan Diego
9h 19m
1 stop
EYW10:59 amKey West
$567
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Key West to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 5, 2025.
Use the filters below to find and compare flights from Key West to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

jue. 9/11

2:00 pm-6:10 pm

1 stop7h 10m

San Diego

lun. 9/15

8:00 am-8:07 pm

1 stop9h 07m

$309

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

jue. 9/11

1:59 pm-9:48 pm

2 stops10h 49m

San Diego

lun. 9/15

9:19 pm-11:13 am

1 stop10h 54m

$314

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

jue. 9/11

11:25 am-8:16 pm

2 stops11h 51m

San Diego

lun. 9/15

10:32 pm-10:54 am

2 stops9h 22m

$319

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

mié. 11/5

4:26 pm-10:22 pm

1 stop8h 56m

San Diego

jue. 11/13

6:15 am-7:29 pm

2 stops10h 14m

$379

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

mié. 11/5

1:45 pm-10:20 pm

2 stops11h 35m

San Diego

jue. 11/13

6:15 am-7:29 pm

2 stops10h 14m

$384

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

mié. 11/5

2:39 pm-8:20 pm

1 stop8h 41m

San Diego

jue. 11/13

10:35 pm-11:08 am

1 stop9h 33m

$446

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

lun. 11/24

7:00 am-1:05 pm

1 stop9h 05m

San Diego

lun. 11/24

10:40 pm-10:59 am

1 stop9h 19m

$567

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

vie. 9/12

8:47 am-7:29 am

3 stops25h 42m

San Diego

dom. 9/14

11:59 am-11:52 am

2 stops20h 53m

$575

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

jue. 9/11

3:50 pm-3:01 pm

2 stops26h 11m

San Diego

lun. 9/15

4:11 pm-2:01 pm

3 stops18h 50m

$598

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

mié. 11/5

3:05 pm-9:14 am

2 stops21h 09m

San Diego

jue. 11/13

5:55 pm-3:19 pm

3 stops18h 24m

$716

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Key West to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Key West to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $333. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $546. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $347. Flights in the morning are often more expensive with an average ticket price of $537.

When to book flights from Key West to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to San Diego (EYW to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to San Diego

Best Price Found

$238

Fastest flight time

7h 10m

Direct flights

None

Airports in San Diego

1 airport
The best one-way flight to San Diego from Key West in the past 72 hours is $238. The best round-trip flight deal from Key West to San Diego found on momondo in the last 72 hours is $309.
The fastest flight from Key West to San Diego takes 7h 10m
There are no direct flights from Key West to San Diego. Popular non-direct route for this connection is Key West Airport - San Diego Airport.
There is 1 airport near San Diego: San Diego (SAN)
Search flight deals

  • How far is Key West to San Diego by plane?

    Key West and San Diego are 2204.3 mi apart from one another. Flights usually cover this in 7h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Key West Airport to San Diego Airport?

    Prices for flights from Key West Airport to San Diego Airport were last updated today.

  • How many operators does momondo search for flights from Key West Airport to San Diego Airport?

  • How old do you have to be to fly from Key West Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Key West to San Diego?

Best airlines flying from Key West to San Diego

Compare and see reviews for airlines that fly from Key West to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $299Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
La Mesa
Imperial Beach
Poway
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Key West to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Key West.

Can I find flights from Key West to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Key West to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Key West to San Diego?

momondo helps you find the best flight between Key West and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Key West to San Diego right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Key West to San Diego now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Diego and let you know when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
dom. 8/10
dom. 8/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States