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Cheap flights from Illinois to Panama City from $149

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Panama City departing on 8/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Illinois to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:56 am - 10:48 am
MLI
-
ECP
4h 52m
1 stop
Delta Logo
6:00 am - 10:25 am
ECP
-
MLI
4h 25m
1 stop
$289Delta
Tue, Jul 28 - Wed, Aug 5
Delta Logo
11:00 am - 3:25 pm
STL
-
ECP
4h 25m
1 stop
Delta Logo
6:51 pm - 11:58 pm
ECP
-
STL
5h 07m
1 stop
$297Delta
Mon, Aug 10 - Thu, Aug 20
Delta Logo
5:16 pm - 11:05 pm
MLI
-
ECP
5h 49m
1 stop
Delta Logo
6:00 am - 10:23 am
ECP
-
MLI
4h 23m
1 stop
$299Delta
Fri, Sep 11 - Sat, Sep 19
Southwest Logo
10:15 am - 3:00 pm
STL
-
ECP
4h 45m
1 stop
Southwest Logo
7:45 am - 4:25 pm
ECP
-
STL
8h 40m
2 stops
$302Southwest
Wed, Sep 2 - Wed, Sep 16
Southwest Logo
2:50 pm - 4:35 pm
STL
-
ECP
1h 45mnonstop
Southwest Logo
3:45 pm - 5:30 pm
ECP
-
STL
1h 45mnonstop
$303Southwest
Mon, Aug 17 - Wed, Aug 19
United Airlines Logo
10:47 am - 1:24 pm
ORD
-
ECP
2h 37mnonstop
United Airlines Logo
10:25 am - 1:09 pm
ECP
-
ORD
2h 44mnonstop
$305United Airlines
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
7:40 am - 9:50 am
MDW
-
ECP
2h 10mnonstop
Southwest Logo
2:45 pm - 4:55 pm
ECP
-
MDW
2h 10mnonstop
$305Southwest
Sat, Aug 15 - Sat, Aug 22
United Airlines Logo
10:33 am - 1:06 pm
ORD
-
ECP
2h 33mnonstop
United Airlines Logo
1:47 pm - 4:29 pm
ECP
-
ORD
2h 42mnonstop
$314United Airlines
Mon, Aug 24 - Sat, Aug 29
American Airlines Logo
6:25 pm - 11:49 pm
PIA
-
ECP
5h 24m
1 stop
American Airlines Logo
7:10 am - 4:59 pm
ECP
-
PIA
9h 49m
2 stops
$314American Airlines
Tue, Nov 3 - Sat, Nov 7
American Airlines Logo
12:09 pm - 2:42 pm
ORD
-
ECP
2h 33mnonstop
American Airlines Logo
11:00 am - 3:56 pm
ECP
-
ORD
4h 56m
1 stop
$315American Airlines
Tue, Jul 21 - Tue, Jul 28

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Delta flights from Illinois to Panama City, Florida

Our best Delta deals on Illinois to Panama City, Florida flight tickets
Delta
Jul 28
MLI5:56 amMoline Quad-City
4h 52m
1 stop
ECP10:48 amPanama City NW Florida Beaches
Aug 5
ECP6:00 amPanama City NW Florida Beaches
4h 25m
1 stop
MLI10:25 amMoline Quad-City
$289
Delta
Aug 10
STL11:00 amLambert-St Louis
4h 25m
1 stop
ECP3:25 pmPanama City NW Florida Beaches
Aug 20
ECP6:51 pmPanama City NW Florida Beaches
5h 07m
1 stop
STL11:58 pmLambert-St Louis
$297
Delta
Aug 3
MLI6:00 amMoline Quad-City
6h 48m
1 stop
ECP12:48 pmPanama City NW Florida Beaches
Aug 12
ECP9:27 amPanama City NW Florida Beaches
6h 55m
1 stop
MLI4:22 pmMoline Quad-City
$299

Southwest flights from Illinois to Panama City, Florida

Our best Southwest deals on Illinois to Panama City, Florida flight tickets
Southwest
Sep 2
STL10:15 amLambert-St Louis
4h 45m
1 stop
ECP3:00 pmPanama City NW Florida Beaches
Sep 16
ECP7:45 amPanama City NW Florida Beaches
8h 40m
2 stops
STL4:25 pmLambert-St Louis
$302
Southwest
Aug 17
STL2:50 pmLambert-St Louis
1h 45m
ECP4:35 pmPanama City NW Florida Beaches
Aug 19
ECP3:45 pmPanama City NW Florida Beaches
1h 45m
STL5:30 pmLambert-St Louis
$303
Southwest
Aug 15
MDW7:40 amChicago Midway
2h 10m
ECP9:50 amPanama City NW Florida Beaches
Aug 22
ECP2:45 pmPanama City NW Florida Beaches
2h 10m
MDW4:55 pmChicago Midway
$305

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Illinois to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Tue 7/28

5:56 am-10:48 am

1 stop4h 52m

Panama City NW Florida Beaches

Wed 8/5

6:00 am-10:25 am

1 stop4h 25m

$289

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 8/10

11:00 am-3:25 pm

1 stop4h 25m

Panama City NW Florida Beaches

Thu 8/20

6:51 pm-11:58 pm

1 stop5h 07m

$297

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Fri 9/11

5:16 pm-11:05 pm

1 stop5h 49m

Panama City NW Florida Beaches

Sat 9/19

6:00 am-10:23 am

1 stop4h 23m

$299

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 9/2

10:15 am-3:00 pm

1 stop4h 45m

Panama City NW Florida Beaches

Wed 9/16

7:45 am-4:25 pm

2 stops8h 40m

$302
Quickest round-trip

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 8/17

2:50 pm-4:35 pm

Nonstop1h 45m

Panama City NW Florida Beaches

Wed 8/19

3:45 pm-5:30 pm

Nonstop1h 45m

$303

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Tue 7/21

10:47 am-1:24 pm

Nonstop2h 37m

Panama City NW Florida Beaches

Tue 7/28

10:25 am-1:09 pm

Nonstop2h 44m

$305

ChicagoPanama City

MDW - ECP

MDWECP

Chicago Midway

Sat 8/15

7:40 am-9:50 am

Nonstop2h 10m

Panama City NW Florida Beaches

Sat 8/22

2:45 pm-4:55 pm

Nonstop2h 10m

$305

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Mon 8/24

10:33 am-1:06 pm

Nonstop2h 33m

Panama City NW Florida Beaches

Sat 8/29

1:47 pm-4:29 pm

Nonstop2h 42m

$314

PeoriaPanama City

PIA - ECP

PIAECP

Greater Peoria

Tue 11/3

6:25 pm-11:49 pm

1 stop5h 24m

Panama City NW Florida Beaches

Sat 11/7

7:10 am-4:59 pm

2 stops9h 49m

$314

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Tue 7/21

12:09 pm-2:42 pm

Nonstop2h 33m

Panama City NW Florida Beaches

Tue 7/28

11:00 am-3:56 pm

1 stop4h 56m

$315

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Illinois to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Illinois is in July. Flight prices, which tend to average around $87, are often lower during this time because this is during the off-season. The month of May is another great option to travel to Panama City, Florida, with average flight prices from Illinois averaging around $103.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $331. On the other hand, Thursday is the most expensive day to depart from Illinois because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $441.

What is the cheapest Illinois to Panama City NW Florida Beaches flight route?

Fly from Chicago O'Hare Intl to Panama City NW Florida Beaches for the best Illinois - Panama City NW Florida Beaches flight prices

How far in advance should I book a flight from Illinois to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Illinois when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $381 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Illinois for as low as $329 on momondo.

What cabin class options are available on Illinois to Panama City, Florida flights?

There are 4 cabin classes available to choose from on Illinois to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Illinois to Panama City, Florida flights?

You could potentially save up to 5% on your flight if you consider stops on a Illinois to Panama City, Florida flight.

Cheap Illinois to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Panama City, Florida

Best Price Found

$189

Fastest flight time

1h 45m

Direct flights

Every day

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Illinois in the past 72 hours is $189. The best round-trip flight deal from Illinois to Panama City, Florida found on momondo in the last 72 hours is $378.
The fastest flight from Illinois to Panama City, Florida takes 1h 45m
Direct flights go from Illinois to Panama City, Florida every day.
There is 1 airport in Panama City, Florida. From Illinois there are direct flights to Panama City NW Florida Beaches (ECP).
Search flight deals

Frequently asked questions about flying from Illinois to Panama City, Florida

  • When did momondo last update prices for flights from Illinois to Panama City NW Florida Beaches Airport?

    Prices for flights from Illinois to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Illinois to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Illinois to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Illinois to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Illinois to Panama City, Florida?

Best airlines flying from Illinois to Panama City, Florida

Compare and see reviews for airlines that fly from Illinois to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $133Free CancellationRating
7.8
8,449 reviews
Search Delta flights
American AirlinesPriceFrom $207Free CancellationRating
7.1
11,768 reviews
Search American Airlines flights
United AirlinesPriceFrom $223Free CancellationRating
7.4
9,894 reviews
Search United Airlines flights
SouthwestPriceFrom $226Free CancellationRating
7.9
4,246 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Illinois to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Illinois to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Illinois on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Illinois to Panama City?

Once all potential Illinois to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Illinois to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Illinois to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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