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Cheap flights from Illinois to Panama City from $158

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Panama City departing on 7/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Illinois to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:09 pm - 11:30 pm
MLI
-
ECP
6h 21m
1 stop
Delta Logo
11:31 am - 4:22 pm
ECP
-
MLI
4h 51m
1 stop
$289Delta
Tue, Aug 11 - Wed, Aug 19
American Airlines Logo
11:11 am - 6:26 pm
MLI
-
ECP
7h 15m
2 stops
American Airlines Logo
3:12 pm - 11:30 pm
ECP
-
MLI
8h 18m
1 stop
$294American Airlines
Tue, Jun 23 - Wed, Jul 8
Delta Logo
5:07 pm - 10:58 pm
MLI
-
ECP
5h 51m
1 stop
Delta Logo
11:38 am - 4:22 pm
ECP
-
MLI
4h 44m
1 stop
$299Delta
Sat, Jul 11 - Wed, Jul 15
Delta Logo
5:09 pm - 11:30 pm
MLI
-
ECP
6h 21m
1 stop
Delta Logo
9:27 am - 4:22 pm
ECP
-
MLI
6h 55m
1 stop
$304Delta
Wed, Aug 12 - Mon, Aug 17
American Airlines Logo
4:45 pm - 10:36 pm
MLI
-
ECP
5h 51m
1 stop
American Airlines Logo
7:05 am - 6:26 pm
ECP
-
MLI
11h 21m
2 stops
$309American Airlines
Sun, May 24 - Sat, May 30
Delta Logo
5:56 am - 12:34 pm
MLI
-
ECP
6h 38m
1 stop
Delta Logo
6:00 am - 10:20 am
ECP
-
MLI
4h 20m
1 stop
$314Delta
Sun, May 24 - Sat, May 30
Delta Logo
7:12 pm - 11:44 pm
STL
-
ECP
4h 32m
1 stop
Delta Logo
5:08 pm - 10:18 pm
ECP
-
STL
5h 10m
1 stop
$315Delta
Mon, Jun 15 - Fri, Jun 19
Southwest Logo
2:10 pm - 7:25 pm
STL
-
ECP
5h 15m
1 stop
Southwest Logo
6:55 am - 3:20 pm
ECP
-
STL
8h 25m
2 stops
$321Southwest
Sat, Jun 6 - Thu, Jun 11
Southwest Logo
7:25 pm - 9:10 pm
STL
-
ECP
1h 45mnonstop
Southwest Logo
5:25 pm - 11:00 pm
ECP
-
STL
5h 35m
1 stop
$326Southwest
Tue, Jun 16 - Tue, Jun 23
United Airlines Logo
7:00 am - 9:37 am
ORD
-
ECP
2h 37mnonstop
United Airlines Logo
2:15 pm - 4:46 pm
ECP
-
ORD
2h 31mnonstop
$352United Airlines
Sat, Sep 26 - Tue, Sep 29

American Airlines flights from Illinois to Panama City, Florida

Our best American Airlines deals on Illinois to Panama City, Florida flight tickets
American Airlines
May 24
MLI4:45 pmMoline Quad-City
5h 51m
1 stop
ECP10:36 pmPanama City NW Florida Beaches
May 30
ECP7:05 amPanama City NW Florida Beaches
11h 21m
2 stops
MLI6:26 pmMoline Quad-City
$309
American Airlines
Jun 27
PIA4:27 pmGreater Peoria
7h 13m
1 stop
ECP11:40 pmPanama City NW Florida Beaches
Jul 3
ECP6:54 pmPanama City NW Florida Beaches
5h 03m
1 stop
PIA11:57 pmGreater Peoria
$319
American Airlines
Sep 26
STL10:34 amLambert-St Louis
8h 16m
2 stops
ECP6:50 pmPanama City NW Florida Beaches
Sep 29
ECP2:36 pmPanama City NW Florida Beaches
4h 22m
1 stop
STL6:58 pmLambert-St Louis
$320

Delta flights from Illinois to Panama City, Florida

Our best Delta deals on Illinois to Panama City, Florida flight tickets
Delta
Aug 11
MLI5:09 pmMoline Quad-City
6h 21m
1 stop
ECP11:30 pmPanama City NW Florida Beaches
Aug 19
ECP11:31 amPanama City NW Florida Beaches
4h 51m
1 stop
MLI4:22 pmMoline Quad-City
$289
Delta
Jul 3
MLI5:17 pmMoline Quad-City
4h 42m
1 stop
ECP9:59 pmPanama City NW Florida Beaches
Jul 8
ECP6:00 amPanama City NW Florida Beaches
4h 22m
1 stop
MLI10:22 amMoline Quad-City
$294
Delta
Jul 11
MLI5:07 pmMoline Quad-City
5h 51m
1 stop
ECP10:58 pmPanama City NW Florida Beaches
Jul 15
ECP11:38 amPanama City NW Florida Beaches
4h 44m
1 stop
MLI4:22 pmMoline Quad-City
$299

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Illinois to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Tue 8/11

5:09 pm-11:30 pm

1 stop6h 21m

Panama City NW Florida Beaches

Wed 8/19

11:31 am-4:22 pm

1 stop4h 51m

$289

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Tue 6/23

11:11 am-6:26 pm

2 stops7h 15m

Panama City NW Florida Beaches

Wed 7/8

3:12 pm-11:30 pm

1 stop8h 18m

$294

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 7/11

5:07 pm-10:58 pm

1 stop5h 51m

Panama City NW Florida Beaches

Wed 7/15

11:38 am-4:22 pm

1 stop4h 44m

$299

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Wed 8/12

5:09 pm-11:30 pm

1 stop6h 21m

Panama City NW Florida Beaches

Mon 8/17

9:27 am-4:22 pm

1 stop6h 55m

$304

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sun 5/24

4:45 pm-10:36 pm

1 stop5h 51m

Panama City NW Florida Beaches

Sat 5/30

7:05 am-6:26 pm

2 stops11h 21m

$309

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sun 5/24

5:56 am-12:34 pm

1 stop6h 38m

Panama City NW Florida Beaches

Sat 5/30

6:00 am-10:20 am

1 stop4h 20m

$314

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 6/15

7:12 pm-11:44 pm

1 stop4h 32m

Panama City NW Florida Beaches

Fri 6/19

5:08 pm-10:18 pm

1 stop5h 10m

$315

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sat 6/6

2:10 pm-7:25 pm

1 stop5h 15m

Panama City NW Florida Beaches

Thu 6/11

6:55 am-3:20 pm

2 stops8h 25m

$321

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Tue 6/16

7:25 pm-9:10 pm

Nonstop1h 45m

Panama City NW Florida Beaches

Tue 6/23

5:25 pm-11:00 pm

1 stop5h 35m

$326
Quickest round-trip

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Sat 9/26

7:00 am-9:37 am

Nonstop2h 37m

Panama City NW Florida Beaches

Tue 9/29

2:15 pm-4:46 pm

Nonstop2h 31m

$352

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Illinois to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Illinois is in July. Flight prices, which tend to average around $87, are often lower during this time because this is during the off-season. The month of June is another great option to travel to Panama City, Florida, with average flight prices from Illinois averaging around $87.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $329. On the other hand, Thursday is the most expensive day to depart from Illinois because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $432.

What is the cheapest Illinois to Panama City NW Florida Beaches flight route?

Fly from Chicago O'Hare Intl to Panama City NW Florida Beaches for the best Illinois - Panama City NW Florida Beaches flight prices

How far in advance should I book a flight from Illinois to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Illinois when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $383 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Illinois for as low as $306 on momondo.

Can stopping save me money on Illinois to Panama City, Florida flights?

No. A direct flight is the cheapest option for a flight between Illinois to Panama City, Florida.

Cheap Illinois to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Panama City, Florida

Best Price Found

$180

Fastest flight time

1h 45m

Direct flights

Every day

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Illinois in the past 72 hours is $180. The best round-trip flight deal from Illinois to Panama City, Florida found on momondo in the last 72 hours is $371.
The fastest flight from Illinois to Panama City, Florida takes 1h 45m
Direct flights go from Illinois to Panama City, Florida every day.
There is 1 airport in Panama City, Florida. From Illinois there are direct flights to Panama City NW Florida Beaches (ECP).
Search flight deals

Frequently asked questions about flying from Illinois to Panama City, Florida

  • When did momondo last update prices for flights from Illinois to Panama City NW Florida Beaches Airport?

    Prices for flights from Illinois to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Illinois to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Illinois to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Illinois to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Illinois to Panama City, Florida?

Best airlines flying from Illinois to Panama City, Florida

Compare and see reviews for airlines that fly from Illinois to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $133Free CancellationRating
7.9
8,450 reviews
Search Delta flights
American AirlinesPriceFrom $207Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights
United AirlinesPriceFrom $218Free CancellationRating
7.4
9,706 reviews
Search United Airlines flights
SouthwestPriceFrom $226Free CancellationRating
7.9
4,296 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Illinois to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Illinois to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Illinois on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Illinois to Panama City?

Once all potential Illinois to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Illinois to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Illinois to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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