What is the cheapest airline that flies from Des Moines to Roanoke?

United Airlines is the most popular carrier operating from Des Moines to Roanoke

When did momondo last update prices for flights from Des Moines Airport to Roanoke Airport?

Prices for flights from Des Moines Airport to Roanoke Airport are updated daily.

How many operators does momondo search for flights from Des Moines Airport to Roanoke Airport?

The number of operators available for flights from Des Moines Airport to Roanoke Airport is 2 as of November 2025.

How old do you have to be to fly from Des Moines Airport to Roanoke Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Roanoke Airport.

What documentation or ID do you need to fly to Roanoke Airport?

The necessary travel and health documents for your Roanoke Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$247 Cheap Flights from Des Moines to Roanoke in 2025/26

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Find the cheapest flights from Des Moines to Roanoke

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

3:17 pm - 8:45 pmDSM-ROA

4h 28m1 stop

5:40 pm - 9:37 pmROA-DSM

4h 57m1 stop

$279United Airlines

Find Deal

Tue, Dec 9 - Sat, Dec 13

6:00 am - 4:24 pmDSM-ROA

9h 24m2 stops

6:30 am - 1:19 pmROA-DSM

7h 49m1 stop

$284American Airlines

Find Deal

Tue, Dec 9 - Sat, Dec 13

5:16 pm - 11:49 pmDSM-ROA

5h 33m1 stop

6:00 am - 12:14 pmROA-DSM

7h 14m1 stop

$304Delta

Find Deal

Tue, Feb 10 - Sat, Feb 14

4:22 pm - 11:49 pmDSM-ROA

6h 27m2 stops

6:00 am - 12:14 pmROA-DSM

7h 14m1 stop

$309Delta

Find Deal

Tue, Feb 10 - Sat, Feb 14

2:59 pm - 12:11 amDSM-ROA

8h 12m2 stops

6:00 am - 2:26 pmROA-DSM

9h 26m2 stops

$334Delta

Find Deal

Tue, Dec 9 - Sat, Dec 13

8:00 am - 2:46 pmDSM-ROA

5h 46m1 stop

10:15 am - 8:34 pmROA-DSM

11h 19m2 stops

$339United Airlines

Find Deal

Tue, Jan 6 - Tue, Jan 13

4:22 pm - 11:49 pmDSM-ROA

6h 27m2 stops

6:00 am - 9:17 pmROA-DSM

16h 17m2 stops

$408Delta

Find Deal

Tue, Feb 10 - Sat, Feb 14

4:21 pm - 11:49 pmDSM-ROA

6h 28m2 stops

6:00 am - 4:59 pmROA-DSM

11h 59m2 stops

$414Delta

Find Deal

Tue, Feb 10 - Sat, Feb 14

10:30 am - 11:49 pmDSM-ROA

12h 19m2 stops

6:00 am - 9:17 pmROA-DSM

16h 17m2 stops

$428Delta

Find Deal

Tue, Feb 10 - Sat, Feb 14

8:00 am - 7:31 pmDSM-ROA

10h 31m2 stops

10:15 am - 8:34 pmROA-DSM

11h 19m2 stops

$443United Airlines

Find Deal

Tue, Jan 6 - Tue, Jan 13

United Airlines flights from Des Moines to Roanoke

Our best United Airlines deals on Des Moines to Roanoke flight tickets

United Airlines

Dec 9

DSM3:17 pmDes Moines

4h 28m

1 stop

ROA8:45 pmRoanoke

Dec 13

ROA5:40 pmRoanoke

4h 57m

1 stop

DSM9:37 pmDes Moines

$279

Find similar

United Airlines

Jan 6

DSM8:00 amDes Moines

5h 46m

1 stop

ROA2:46 pmRoanoke

Jan 13

ROA10:15 amRoanoke

11h 19m

2 stops

DSM8:34 pmDes Moines

$339

Find similar

United Airlines

Nov 25

DSM1:05 pmDes Moines

7h 03m

1 stop

ROA9:08 pmRoanoke

Nov 29

ROA6:45 amRoanoke

4h 57m

1 stop

DSM10:42 amDes Moines

$424

Find similar

American Airlines flights from Des Moines to Roanoke

Our best American Airlines deals on Des Moines to Roanoke flight tickets

American Airlines

Dec 9

DSM6:00 amDes Moines

9h 24m

2 stops

ROA4:24 pmRoanoke

Dec 13

ROA6:30 amRoanoke

7h 49m

1 stop

DSM1:19 pmDes Moines

$284

Find similar

American Airlines

Dec 3

DSM5:01 pmDes Moines

5h 58m

1 stop

ROA11:59 pmRoanoke

Dec 6

ROA7:04 amRoanoke

5h 38m

1 stop

DSM11:42 amDes Moines

$526

Find similar

American Airlines

Dec 3

DSM6:48 amDes Moines

8h 36m

1 stop

ROA4:24 pmRoanoke

Dec 6

ROA7:04 amRoanoke

5h 38m

1 stop

DSM11:42 amDes Moines

$553

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 12/9

3:17 pm-8:45 pm

1 stop4h 28m

Roanoke

Sat 12/13

5:40 pm-9:37 pm

1 stop4h 57m

$279

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 12/9

6:00 am-4:24 pm

2 stops9h 24m

Roanoke

Sat 12/13

6:30 am-1:19 pm

1 stop7h 49m

$284

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 2/10

5:16 pm-11:49 pm

1 stop5h 33m

Roanoke

Sat 2/14

6:00 am-12:14 pm

1 stop7h 14m

$304

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 2/10

4:22 pm-11:49 pm

2 stops6h 27m

Roanoke

Sat 2/14

6:00 am-12:14 pm

1 stop7h 14m

$309

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 12/9

2:59 pm-12:11 am

2 stops8h 12m

Roanoke

Sat 12/13

6:00 am-2:26 pm

2 stops9h 26m

$334

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 1/6

8:00 am-2:46 pm

1 stop5h 46m

Roanoke

Tue 1/13

10:15 am-8:34 pm

2 stops11h 19m

$339

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 2/10

4:22 pm-11:49 pm

2 stops6h 27m

Roanoke

Sat 2/14

6:00 am-9:17 pm

2 stops16h 17m

$408

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 2/10

4:21 pm-11:49 pm

2 stops6h 28m

Roanoke

Sat 2/14

6:00 am-4:59 pm

2 stops11h 59m

$414

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 2/10

10:30 am-11:49 pm

2 stops12h 19m

Roanoke

Sat 2/14

6:00 am-9:17 pm

2 stops16h 17m

$428

Des MoinesRoanoke

DSM - ROA

DSMROA

Des Moines

Tue 1/6

8:00 am-7:31 pm

2 stops10h 31m

Roanoke

Tue 1/13

10:15 am-8:34 pm

2 stops11h 19m

$443

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Roanoke?

The month of August is, on average, the cheapest month to fly to Roanoke from Des Moines, with most prices found around $256. If you aren’t able to travel to Roanoke during the month of August, then flying in December is also cheap. Prices for this month can be found on momondo for an average of $278.

What is the cheapest day to depart on your flight to Roanoke?

Our data shows that Tuesday is the least expensive day to fly to Roanoke. Tickets to fly out on this day can be as low as $278. Flights from Des Moines to Roanoke on a Sunday will generally be more expensive and average around $459. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Roanoke?

Our most recent data shows that the best time of day to fly to Roanoke is at noon. Flights from Des Moines to Roanoke during this time can be as low as $290. In contrast, the most expensive time of day to depart to Roanoke is in the morning when prices are around $388.

When to book flights from Des Moines to Roanoke

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Roanoke according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Roanoke (DSM to ROA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Roanoke

Direct flights	None

There are no direct flights from Des Moines to Roanoke. There are no popular flight routes from Des Moines to Roanoke.

Search flight deals

How far is Des Moines to Roanoke by plane?
The distance between Des Moines and Roanoke is about 787.3 mi. Typically, this will take 4h 28m by plane in normal conditions.
When did momondo last update prices for flights from Des Moines Airport to Roanoke Airport?
Prices for flights from Des Moines Airport to Roanoke Airport are updated daily.
How many operators does momondo search for flights from Des Moines Airport to Roanoke Airport?
The number of operators available for flights from Des Moines Airport to Roanoke Airport is 2 as of November 2025.
How old do you have to be to fly from Des Moines Airport to Roanoke Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Roanoke Airport.
What documentation or ID do you need to fly to Roanoke Airport?
The necessary travel and health documents for your Roanoke Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Roanoke?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Roanoke is American Airlines (74% of total bookings). The next most popular airline is Delta (26%).

Best airlines flying from Des Moines to Roanoke

Compare and see reviews for airlines that fly from Des Moines to Roanoke with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,046 reviews		Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 7,997 reviews		Search Delta flights

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Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Roanoke?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Roanoke. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Roanoke with flexible booking policies on momondo?

Flights from Des Moines to Roanoke with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Roanoke?

momondo helps you find the best flight between Des Moines and Roanoke by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Roanoke right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Roanoke, momondo offers a useful price alert feature which will track prices for flights to Roanoke from Des Moines and alert you when they change.