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Cheap flights from Des Moines to Myrtle Beach from $129

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Myrtle Beach departing on 7/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Myrtle Beach

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:00 am - 2:19 pm
DSM
-
MYR
7h 19m
1 stop
United Airlines Logo
3:15 pm - 9:22 pm
MYR
-
DSM
7h 07m
1 stop
$317United Airlines
Wed, Jul 15 - Wed, Jul 22
United Airlines Logo
8:00 am - 2:19 pm
DSM
-
MYR
5h 19m
1 stop
United Airlines Logo
10:34 am - 9:22 pm
MYR
-
DSM
11h 48m
2 stops
$322United Airlines
Wed, Jul 15 - Wed, Jul 22
Multiple Airlines Logo
4:40 pm - 9:50 am
DSM
-
MYR
16h 10m
1 stop
Multiple Airlines Logo
8:41 pm - 10:47 pm
MYR
-
DSM
51h 06m
2 stops
$324Multiple Airlines
Mon, Jul 13 - Fri, Jul 17
Multiple Airlines Logo
4:40 pm - 9:50 am
DSM
-
MYR
16h 10m
1 stop
Multiple Airlines Logo
8:41 pm - 9:31 pm
MYR
-
DSM
49h 50m
2 stops
$325Multiple Airlines
Mon, Aug 3 - Fri, Aug 7
Southwest Logo
6:10 am - 4:05 pm
DSM
-
MYR
8h 55m
2 stops
Southwest Logo
11:00 am - 9:00 pm
MYR
-
DSM
11h 00m
2 stops
$327Southwest
Wed, Aug 26 - Wed, Sep 2
Multiple Airlines Logo
1:49 pm - 10:05 am
DSM
-
MYR
19h 16m
2 stops
Multiple Airlines Logo
6:23 pm - 9:31 pm
MYR
-
DSM
28h 08m
1 stop
$329Multiple Airlines
Wed, Aug 5 - Sat, Aug 8
Multiple Airlines Logo
4:40 pm - 9:50 am
DSM
-
MYR
16h 10m
1 stop
Multiple Airlines Logo
1:06 pm - 11:07 pm
MYR
-
DSM
11h 01m
2 stops
$330Multiple Airlines
Mon, Jul 13 - Thu, Jul 16
American Airlines Logo
7:04 am - 3:31 pm
DSM
-
MYR
7h 27m
1 stop
American Airlines Logo
6:10 pm - 12:09 am
MYR
-
DSM
6h 59m
1 stop
$334American Airlines
Fri, Jul 3 - Tue, Jul 7
Multiple Airlines Logo
4:40 pm - 9:50 am
DSM
-
MYR
16h 10m
1 stop
Multiple Airlines Logo
8:41 pm - 10:47 pm
MYR
-
DSM
51h 06m
2 stops
$337Multiple Airlines
Mon, Jul 13 - Fri, Jul 17
United Airlines Logo
6:15 am - 2:33 pm
DSM
-
MYR
7h 18m
1 stop
United Airlines Logo
11:25 am - 8:32 pm
MYR
-
DSM
10h 07m
2 stops
$342United Airlines
Mon, Dec 7 - Sat, Dec 12

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Southwest flights from Des Moines to Myrtle Beach

Our best Southwest deals on Des Moines to Myrtle Beach flight tickets
Southwest
Aug 26
DSM6:10 amDes Moines
8h 55m
2 stops
MYR4:05 pmMyrtle Beach Intl
Sep 2
MYR11:00 amMyrtle Beach Intl
11h 00m
2 stops
DSM9:00 pmDes Moines
$327
Southwest
Jul 25
DSM3:35 pmDes Moines
4h 35m
1 stop
MYR9:10 pmMyrtle Beach Intl
Jul 29
MYR7:00 amMyrtle Beach Intl
9h 05m
1 stop
DSM3:05 pmDes Moines
$357
Southwest
Sep 2
DSM6:10 amDes Moines
8h 55m
2 stops
MYR4:05 pmMyrtle Beach Intl
Sep 3
MYR3:20 pmMyrtle Beach Intl
7h 50m
2 stops
DSM10:10 pmDes Moines
$399

American Airlines flights from Des Moines to Myrtle Beach

Our best American Airlines deals on Des Moines to Myrtle Beach flight tickets
American Airlines
Jul 3
DSM7:04 amDes Moines
7h 27m
1 stop
MYR3:31 pmMyrtle Beach Intl
Jul 7
MYR6:10 pmMyrtle Beach Intl
6h 59m
1 stop
DSM12:09 amDes Moines
$334
American Airlines
Sep 2
DSM5:10 pmDes Moines
4h 28m
1 stop
MYR10:38 pmMyrtle Beach Intl
Sep 3
MYR12:14 pmMyrtle Beach Intl
8h 05m
2 stops
DSM7:19 pmDes Moines
$363
American Airlines
Sep 13
DSM6:00 amDes Moines
8h 32m
2 stops
MYR3:32 pmMyrtle Beach Intl
Sep 19
MYR8:08 amMyrtle Beach Intl
4h 56m
1 stop
DSM12:04 pmDes Moines
$367

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Wed 7/15

6:00 am-2:19 pm

1 stop7h 19m

Myrtle Beach Intl

Wed 7/22

3:15 pm-9:22 pm

1 stop7h 07m

$317

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Wed 7/15

8:00 am-2:19 pm

1 stop5h 19m

Myrtle Beach Intl

Wed 7/22

10:34 am-9:22 pm

2 stops11h 48m

$322

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 7/13

4:40 pm-9:50 am

1 stop16h 10m

Myrtle Beach Intl

Fri 7/17

8:41 pm-10:47 pm

2 stops51h 06m

$324

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 8/3

4:40 pm-9:50 am

1 stop16h 10m

Myrtle Beach Intl

Fri 8/7

8:41 pm-9:31 pm

2 stops49h 50m

$325

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Wed 8/26

6:10 am-4:05 pm

2 stops8h 55m

Myrtle Beach Intl

Wed 9/2

11:00 am-9:00 pm

2 stops11h 00m

$327

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Wed 8/5

1:49 pm-10:05 am

2 stops19h 16m

Myrtle Beach Intl

Sat 8/8

6:23 pm-9:31 pm

1 stop28h 08m

$329

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 7/13

4:40 pm-9:50 am

1 stop16h 10m

Myrtle Beach Intl

Thu 7/16

1:06 pm-11:07 pm

2 stops11h 01m

$330

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Fri 7/3

7:04 am-3:31 pm

1 stop7h 27m

Myrtle Beach Intl

Tue 7/7

6:10 pm-12:09 am

1 stop6h 59m

$334

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 7/13

4:40 pm-9:50 am

1 stop16h 10m

Myrtle Beach Intl

Fri 7/17

8:41 pm-10:47 pm

2 stops51h 06m

$337

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 12/7

6:15 am-2:33 pm

1 stop7h 18m

Myrtle Beach Intl

Sat 12/12

11:25 am-8:32 pm

2 stops10h 07m

$342

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Des Moines to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Myrtle Beach?

What is the cheapest month to fly to Myrtle Beach?

In general, January is the cheapest month to fly from Des Moines to Myrtle Beach. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $293. If you are unable to visit Myrtle Beach during the month of January, then departing from Des Moines during the month August is also very affordable. Most momondo users find prices during this month for around $297.

Can stopping save me money on Des Moines to Myrtle Beach flights?

You could potentially save up to 31% on your flight if you consider stops on a Des Moines to Myrtle Beach flight.

When to book flights from Des Moines to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Myrtle Beach (DSM to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Myrtle Beach

Fastest flight time

4h 05m

Direct flights

None
The fastest flight from Des Moines to Myrtle Beach takes 4h 05m
There are no direct flights from Des Moines to Myrtle Beach. There are no popular flight routes from Des Moines to Myrtle Beach.
Search flight deals

Frequently asked questions about flying from Des Moines to Myrtle Beach

  • How far is Des Moines to Myrtle Beach Intl by plane?

    A flight from Des Moines to Myrtle Beach Intl will travel around 970.9 mi. Flights usually cover this in 4h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Myrtle Beach Intl Airport?

    Prices for flights from Des Moines Airport to Myrtle Beach Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Myrtle Beach Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Myrtle Beach Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The travel and health documents you'll need for your trip to Myrtle Beach Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Myrtle Beach Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Myrtle Beach?

Best airlines flying from Des Moines to Myrtle Beach

Compare and see reviews for airlines that fly from Des Moines to Myrtle Beach with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,724 reviews
Search American Airlines flights
SouthwestPriceFrom $272Free CancellationRating
7.9
4,242 reviews
Search Southwest flights
DeltaPriceFrom $302Free CancellationRating
7.8
8,423 reviews
Search Delta flights

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Ocean Isle Beach
Sunset Beach
Surfside Beach
Murrells Inlet
Garden City Beach
Conway
Georgetown
Little River

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Myrtle Beach?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Myrtle Beach. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Myrtle Beach from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Myrtle Beach?

Once all potential Des Moines to Myrtle Beach flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Myrtle Beach right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Myrtle Beach from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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