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Cheap flights from Des Moines to Myrtle Beach from $132

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Myrtle Beach departing on 6/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Myrtle Beach

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:00 am - 8:48 pm
DSM
-
MYR
12h 48m
1 stop
Multiple Airlines Logo
3:29 pm - 1:46 pm
MYR
-
DSM
23h 17m
1 stop
$229Multiple Airlines
Sun, Apr 5 - Wed, Apr 8
Multiple Airlines Logo
7:00 am - 8:48 pm
DSM
-
MYR
12h 48m
1 stop
Multiple Airlines Logo
6:28 pm - 1:46 pm
MYR
-
DSM
20h 18m
2 stops
$270Multiple Airlines
Sun, Apr 5 - Wed, Apr 8
Multiple Airlines Logo
8:30 am - 11:29 pm
DSM
-
MYR
13h 59m
1 stop
Multiple Airlines Logo
3:17 pm - 3:15 pm
MYR
-
DSM
24h 58m
1 stop
$284Multiple Airlines
Sun, Apr 26 - Wed, May 6
Multiple Airlines Logo
7:45 am - 8:58 pm
DSM
-
MYR
12h 13m
1 stop
Multiple Airlines Logo
11:52 am - 11:24 pm
MYR
-
DSM
12h 32m
1 stop
$286Multiple Airlines
Sun, May 17 - Fri, May 22
Multiple Airlines Logo
3:21 pm - 5:33 pm
DSM
-
MYR
25h 12m
1 stop
Multiple Airlines Logo
3:29 pm - 1:46 pm
MYR
-
DSM
23h 17m
1 stop
$295Multiple Airlines
Thu, Apr 2 - Wed, Apr 8
Multiple Airlines Logo
3:21 pm - 5:33 pm
DSM
-
MYR
25h 12m
1 stop
Multiple Airlines Logo
3:29 pm - 1:46 pm
MYR
-
DSM
23h 17m
1 stop
$296Multiple Airlines
Thu, Apr 2 - Wed, Apr 8
Multiple Airlines Logo
8:14 pm - 11:05 am
DSM
-
MYR
13h 51m
2 stops
Multiple Airlines Logo
3:29 pm - 1:46 pm
MYR
-
DSM
23h 17m
1 stop
$301Multiple Airlines
Mon, Apr 6 - Wed, Apr 8
Multiple Airlines Logo
8:30 am - 11:29 pm
DSM
-
MYR
13h 59m
1 stop
Multiple Airlines Logo
11:52 am - 10:06 pm
MYR
-
DSM
11h 14m
1 stop
$305Multiple Airlines
Sun, Apr 26 - Thu, Apr 30
Multiple Airlines Logo
7:45 am - 8:58 pm
DSM
-
MYR
12h 13m
1 stop
Multiple Airlines Logo
11:52 am - 11:24 pm
MYR
-
DSM
12h 32m
1 stop
$308Multiple Airlines
Sun, May 17 - Fri, May 22
Multiple Airlines Logo
11:00 am - 11:05 am
DSM
-
MYR
23h 05m
1 stop
Multiple Airlines Logo
3:29 pm - 1:46 pm
MYR
-
DSM
23h 17m
1 stop
$310Multiple Airlines
Sat, Apr 4 - Wed, Apr 8

American Airlines flights from Des Moines to Myrtle Beach

Our best American Airlines deals on Des Moines to Myrtle Beach flight tickets
American Airlines
Apr 15
DSM2:02 pmDes Moines
7h 22m
1 stop
MYR10:24 pmMyrtle Beach Intl
Apr 21
MYR8:14 amMyrtle Beach Intl
5h 38m
1 stop
DSM12:52 pmDes Moines
$335
American Airlines
Apr 15
DSM11:09 amDes Moines
10h 15m
2 stops
MYR10:24 pmMyrtle Beach Intl
Apr 21
MYR8:14 amMyrtle Beach Intl
5h 38m
1 stop
DSM12:52 pmDes Moines
$340
American Airlines
May 13
DSM6:00 amDes Moines
4h 35m
1 stop
MYR11:35 amMyrtle Beach Intl
May 16
MYR6:04 amMyrtle Beach Intl
8h 42m
2 stops
DSM1:46 pmDes Moines
$341

Delta flights from Des Moines to Myrtle Beach

Our best Delta deals on Des Moines to Myrtle Beach flight tickets
Delta
Apr 25
DSM6:31 pmDes Moines
4h 43m
1 stop
MYR12:14 amMyrtle Beach Intl
Apr 29
MYR12:05 pmMyrtle Beach Intl
8h 23m
1 stop
DSM7:28 pmDes Moines
$336
Delta
Apr 25
DSM6:31 pmDes Moines
4h 43m
1 stop
MYR12:14 amMyrtle Beach Intl
May 2
MYR6:11 pmMyrtle Beach Intl
5h 23m
1 stop
DSM10:34 pmDes Moines
$337
Delta
Apr 25
DSM12:01 pmDes Moines
11h 13m
2 stops
MYR12:14 amMyrtle Beach Intl
May 6
MYR12:50 pmMyrtle Beach Intl
9h 22m
2 stops
DSM9:12 pmDes Moines
$346

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 4/5

7:00 am-8:48 pm

1 stop12h 48m

Myrtle Beach Intl

Wed 4/8

3:29 pm-1:46 pm

1 stop23h 17m

$229

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 4/5

7:00 am-8:48 pm

1 stop12h 48m

Myrtle Beach Intl

Wed 4/8

6:28 pm-1:46 pm

2 stops20h 18m

$270

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 4/26

8:30 am-11:29 pm

1 stop13h 59m

Myrtle Beach Intl

Wed 5/6

3:17 pm-3:15 pm

1 stop24h 58m

$284
Quickest round-trip

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 5/17

7:45 am-8:58 pm

1 stop12h 13m

Myrtle Beach Intl

Fri 5/22

11:52 am-11:24 pm

1 stop12h 32m

$286

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 4/2

3:21 pm-5:33 pm

1 stop25h 12m

Myrtle Beach Intl

Wed 4/8

3:29 pm-1:46 pm

1 stop23h 17m

$295

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 4/2

3:21 pm-5:33 pm

1 stop25h 12m

Myrtle Beach Intl

Wed 4/8

3:29 pm-1:46 pm

1 stop23h 17m

$296

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 4/6

8:14 pm-11:05 am

2 stops13h 51m

Myrtle Beach Intl

Wed 4/8

3:29 pm-1:46 pm

1 stop23h 17m

$301

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 4/26

8:30 am-11:29 pm

1 stop13h 59m

Myrtle Beach Intl

Thu 4/30

11:52 am-10:06 pm

1 stop11h 14m

$305

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 5/17

7:45 am-8:58 pm

1 stop12h 13m

Myrtle Beach Intl

Fri 5/22

11:52 am-11:24 pm

1 stop12h 32m

$308

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 4/4

11:00 am-11:05 am

1 stop23h 05m

Myrtle Beach Intl

Wed 4/8

3:29 pm-1:46 pm

1 stop23h 17m

$310

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Des Moines to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Myrtle Beach?

In general, January is the cheapest month to fly from Des Moines to Myrtle Beach. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $291. If you are unable to visit Myrtle Beach during the month of January, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $294.

Can stopping save me money on Des Moines to Myrtle Beach flights?

You could potentially save up to 21% on your flight if you consider stops on a Des Moines to Myrtle Beach flight.

When to book flights from Des Moines to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Myrtle Beach (DSM to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Myrtle Beach

Fastest flight time

4h 08m

Direct flights

None
The fastest flight from Des Moines to Myrtle Beach takes 4h 08m
There are no direct flights from Des Moines to Myrtle Beach. There are no popular flight routes from Des Moines to Myrtle Beach.
Search flight deals

  • How far is Des Moines to Myrtle Beach Intl by plane?

    A flight from Des Moines to Myrtle Beach Intl will travel around 970.9 mi. Flights usually cover this in 4h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Myrtle Beach Intl Airport?

    Prices for flights from Des Moines Airport to Myrtle Beach Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Myrtle Beach Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Myrtle Beach Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The travel and health documents you'll need for your trip to Myrtle Beach Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Myrtle Beach Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Myrtle Beach?

Best airlines flying from Des Moines to Myrtle Beach

Compare and see reviews for airlines that fly from Des Moines to Myrtle Beach with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights
SouthwestPriceFrom $272Free CancellationRating
8.0
4,324 reviews
Search Southwest flights
DeltaPriceFrom $299Free CancellationRating
7.9
8,314 reviews
Search Delta flights

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Sunset Beach
Ocean Isle Beach
Murrells Inlet
Garden City Beach
Surfside Beach
Conway
Little River
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Myrtle Beach?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Myrtle Beach. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Myrtle Beach from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Myrtle Beach?

Once all potential Des Moines to Myrtle Beach flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Myrtle Beach right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Myrtle Beach from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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