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Cheap flights from Des Moines to Myrtle Beach from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Myrtle Beach departing on 11/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Myrtle Beach

Cheap round-trip flights

Delta Logo
12:35 pm - 5:47 pmDSM-MYR
4h 12m1 stop
Delta Logo
6:00 am - 10:40 amMYR-DSM
5h 40m1 stop
$237Delta
Find Deal
Sat, Sep 6 - Sat, Sep 13
Delta Logo
12:35 pm - 11:49 pmDSM-MYR
10h 14m2 stops
Delta Logo
6:00 am - 10:40 amMYR-DSM
5h 40m1 stop
$242Delta
Find Deal
Sat, Sep 6 - Sat, Sep 13
Delta Logo
5:14 pm - 11:59 pmDSM-MYR
5h 45m1 stop
Delta Logo
6:58 pm - 10:43 pmMYR-DSM
4h 45m1 stop
$243Delta
Find Deal
Sat, Oct 18 - Thu, Oct 23
American Airlines Logo
6:00 am - 12:13 pmDSM-MYR
5h 13m1 stop
American Airlines Logo
4:05 pm - 10:09 pmMYR-DSM
7h 04m1 stop
$249American Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Logo
8:00 am - 6:41 pmDSM-MYR
9h 41m1 stop
Logo
2:45 pm - 9:24 amMYR-DSM
19h 39m2 stops
$253
Find Deal
Fri, Sep 12 - Tue, Sep 16
American Airlines Logo
7:34 am - 3:27 pmDSM-MYR
6h 53m1 stop
American Airlines Logo
5:03 pm - 11:17 pmMYR-DSM
7h 14m1 stop
$267American Airlines
Find Deal
Tue, Aug 26 - Sat, Aug 30
Logo
6:00 am - 6:29 pmDSM-MYR
11h 29m1 stop
Logo
6:45 am - 8:12 pmMYR-DSM
14h 27m1 stop
$269
Find Deal
Mon, Aug 18 - Mon, Aug 25
Southwest Logo
8:00 am - 9:30 pmDSM-MYR
12h 30m2 stops
Southwest Logo
2:55 pm - 9:35 pmMYR-DSM
7h 40m2 stops
$289Southwest
Find Deal
Thu, Nov 13 - Mon, Nov 17
Southwest Logo
6:35 am - 7:30 pmDSM-MYR
11h 55m2 stops
Southwest Logo
1:20 pm - 9:50 pmMYR-DSM
9h 30m2 stops
$295Southwest
Find Deal
Fri, Oct 24 - Wed, Oct 29
United Airlines Logo
8:00 am - 2:31 pmDSM-MYR
5h 31m1 stop
United Airlines Logo
3:45 pm - 11:41 pmMYR-DSM
8h 56m1 stop
$307United Airlines
Find Deal
Wed, Aug 27 - Sat, Aug 30

American Airlines flights from Des Moines to Myrtle Beach

Our best American Airlines deals on Des Moines to Myrtle Beach flight tickets
American Airlines
Nov 13
DSM6:00 amDes Moines
5h 13m
1 stop
MYR12:13 pmMyrtle Beach Intl
Nov 17
MYR4:05 pmMyrtle Beach Intl
7h 04m
1 stop
DSM10:09 pmDes Moines
$249
Find similar
American Airlines
Aug 26
DSM7:34 amDes Moines
6h 53m
1 stop
MYR3:27 pmMyrtle Beach Intl
Aug 30
MYR5:03 pmMyrtle Beach Intl
7h 14m
1 stop
DSM11:17 pmDes Moines
$267
Find similar
American Airlines
Aug 26
DSM6:00 amDes Moines
7h 51m
2 stops
MYR2:51 pmMyrtle Beach Intl
Aug 30
MYR5:03 pmMyrtle Beach Intl
7h 14m
1 stop
DSM11:17 pmDes Moines
$272
Find similar

Delta flights from Des Moines to Myrtle Beach

Our best Delta deals on Des Moines to Myrtle Beach flight tickets
Delta
Sep 6
DSM12:35 pmDes Moines
4h 12m
1 stop
MYR5:47 pmMyrtle Beach Intl
Sep 13
MYR6:00 amMyrtle Beach Intl
5h 40m
1 stop
DSM10:40 amDes Moines
$237
Find similar
Delta
Sep 6
DSM12:35 pmDes Moines
10h 14m
2 stops
MYR11:49 pmMyrtle Beach Intl
Sep 13
MYR6:00 amMyrtle Beach Intl
5h 40m
1 stop
DSM10:40 amDes Moines
$242
Find similar
Delta
Oct 18
DSM5:14 pmDes Moines
5h 45m
1 stop
MYR11:59 pmMyrtle Beach Intl
Oct 23
MYR6:58 pmMyrtle Beach Intl
4h 45m
1 stop
DSM10:43 pmDes Moines
$243
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 9/6

12:35 pm-5:47 pm

1 stop4h 12m

Myrtle Beach Intl

Sat 9/13

6:00 am-10:40 am

1 stop5h 40m

$237

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 9/6

12:35 pm-11:49 pm

2 stops10h 14m

Myrtle Beach Intl

Sat 9/13

6:00 am-10:40 am

1 stop5h 40m

$242

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 10/18

5:14 pm-11:59 pm

1 stop5h 45m

Myrtle Beach Intl

Thu 10/23

6:58 pm-10:43 pm

1 stop4h 45m

$243

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 11/13

6:00 am-12:13 pm

1 stop5h 13m

Myrtle Beach Intl

Mon 11/17

4:05 pm-10:09 pm

1 stop7h 04m

$249

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Fri 9/12

8:00 am-6:41 pm

1 stop9h 41m

Myrtle Beach Intl

Tue 9/16

2:45 pm-9:24 am

2 stops19h 39m

$253

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 8/26

7:34 am-3:27 pm

1 stop6h 53m

Myrtle Beach Intl

Sat 8/30

5:03 pm-11:17 pm

1 stop7h 14m

$267

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 8/18

6:00 am-6:29 pm

1 stop11h 29m

Myrtle Beach Intl

Mon 8/25

6:45 am-8:12 pm

1 stop14h 27m

$269

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 11/13

8:00 am-9:30 pm

2 stops12h 30m

Myrtle Beach Intl

Mon 11/17

2:55 pm-9:35 pm

2 stops7h 40m

$289

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Fri 10/24

6:35 am-7:30 pm

2 stops11h 55m

Myrtle Beach Intl

Wed 10/29

1:20 pm-9:50 pm

2 stops9h 30m

$295

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Wed 8/27

8:00 am-2:31 pm

1 stop5h 31m

Myrtle Beach Intl

Sat 8/30

3:45 pm-11:41 pm

1 stop8h 56m

$307

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Des Moines to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Myrtle Beach?

In general, August is the cheapest month to fly from Des Moines to Myrtle Beach. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $276. If you are unable to visit Myrtle Beach during the month of August, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $316.

What is the cheapest day to depart on your flight to Myrtle Beach?

Our data shows that Tuesday is the least expensive day to fly to Myrtle Beach. Tickets to fly out on this day can be as low as $340. The most expensive day to fly to Myrtle Beach is Thursday, with ticket prices averaging around $487.

What is the cheapest time of day to depart on your flight to Myrtle Beach?

The cheapest time of day to fly to Myrtle Beach is in the afternoon when flights can be purchased for as low as $364. Flights in the morning are often more expensive with an average ticket price of $402.

How far in advance should I book a flight to Myrtle Beach?

You are more likely to see cheaper flights to Myrtle Beach from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Myrtle Beach for around $388 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Myrtle Beach from Des Moines for as low as $309 on momondo.

When to book flights from Des Moines to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Myrtle Beach (DSM to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Myrtle Beach

Best Price Found

$113

Fastest flight time

4h 12m

Direct flights

None

Airports in Myrtle Beach

1 airport
The best one-way flight to Myrtle Beach from Des Moines in the past 72 hours is $113. The best round-trip flight deal from Des Moines to Myrtle Beach found on momondo in the last 72 hours is $237.
The fastest flight from Des Moines to Myrtle Beach takes 4h 12m
There are no direct flights from Des Moines to Myrtle Beach. Popular non-direct route for this connection is Des Moines Airport - Myrtle Beach Intl Airport.
There is 1 airport near Myrtle Beach: Myrtle Beach Intl (MYR)
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  • How far is Des Moines to Myrtle Beach Intl by plane?

    A flight from Des Moines to Myrtle Beach Intl will travel around 970.9 mi. Flights usually cover this in 4h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Myrtle Beach Intl Airport?

    Prices for flights from Des Moines Airport to Myrtle Beach Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Myrtle Beach Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Myrtle Beach Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The travel and health documents you'll need for your trip to Myrtle Beach Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Myrtle Beach Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Myrtle Beach?

Best airlines flying from Des Moines to Myrtle Beach

Compare and see reviews for airlines that fly from Des Moines to Myrtle Beach with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $254Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $272Free CancellationRating
8.0
4,246 reviews
Search Southwest flights
DeltaPriceFrom $292Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Sunset Beach
Ocean Isle Beach
Murrells Inlet
Surfside Beach
Garden City Beach
Conway
Little River
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Myrtle Beach?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Myrtle Beach. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Myrtle Beach from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Myrtle Beach?

Once all potential Des Moines to Myrtle Beach flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Myrtle Beach right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Myrtle Beach from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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