What is the cheapest airline that flies from Des Moines to Myrtle Beach Intl?

Delta, Southwest, and American Airlines are the most popular carriers operating from Des Moines to Myrtle Beach Intl

What airlines fly to Myrtle Beach?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Myrtle Beach from Des Moines according to our data. American Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Myrtle Beach. Keep in mind that there are 4 different airlines that fly to Myrtle Beach on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Myrtle Beach Intl Airport?

Prices for flights from Des Moines Airport to Myrtle Beach Intl Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Des Moines Airport to Myrtle Beach Intl Airport?

As of September 2026, there are 3 operators available to choose from for flights from Des Moines Airport to Myrtle Beach Intl Airport.

How old do you have to be to fly from Des Moines Airport to Myrtle Beach Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Myrtle Beach Intl Airport.

What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

The travel and health documents you'll need for your trip to Myrtle Beach Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Myrtle Beach Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$163 Cheap Flights from Des Moines to Myrtle Beach in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Myrtle Beach

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:12 pm - 10:52 pmDSM Des Moines-MYR Myrtle Beach Intl

5h 40m1 stop Dallas/Fort Worth

4:57 pm - 11:07 pmMYR Myrtle Beach Intl-DSM Des Moines

7h 10m1 stop Dallas/Fort Worth

$325American Airlines

Sat, Oct 17 - Sat, Oct 31

6:00 am - 12:56 pmDSM Des Moines-MYR Myrtle Beach Intl

5h 56m1 stop Washington, D.C. Reagan-National

5:03 pm - 11:26 pmMYR Myrtle Beach Intl-DSM Des Moines

7h 23m1 stop Charlotte Douglas

$325American Airlines

Sat, Nov 7 - Wed, Nov 11

2:58 pm - 10:47 pmDSM Des Moines-MYR Myrtle Beach Intl

6h 49m1 stop Atlanta Hartsfield-Jackson

6:00 am - 10:49 amMYR Myrtle Beach Intl-DSM Des Moines

5h 49m1 stop Atlanta Hartsfield-Jackson

$325Delta

Wed, Dec 2 - Tue, Dec 8

2:58 pm - 10:47 pmDSM Des Moines-MYR Myrtle Beach Intl

6h 49m1 stop Atlanta Hartsfield-Jackson

2:18 pm - 6:06 pmMYR Myrtle Beach Intl-DSM Des Moines

4h 48m1 stop Atlanta Hartsfield-Jackson

$325Delta

Wed, Dec 2 - Mon, Dec 7

3:31 pm - 10:34 pmDSM Des Moines-MYR Myrtle Beach Intl

6h 03m1 stop Dallas/Fort Worth

6:12 am - 10:10 amMYR Myrtle Beach Intl-DSM Des Moines

4h 58m1 stop Charlotte Douglas

$325American Airlines

Thu, Dec 3 - Mon, Dec 7

5:15 pm - 10:25 pmDSM Des Moines-MYR Myrtle Beach Intl

4h 10m1 stop Atlanta Hartsfield-Jackson

6:00 am - 10:18 amMYR Myrtle Beach Intl-DSM Des Moines

5h 18m1 stop Atlanta Hartsfield-Jackson

$334Delta

Mon, Jan 11 - Fri, Jan 15

5:20 am - 5:20 pmDSM Des Moines-MYR Myrtle Beach Intl

11h 00m2 stops Chicago Midway Nashville Intl

3:25 pm - 10:05 pmMYR Myrtle Beach Intl-DSM Des Moines

7h 40m2 stops Baltimore/Washington Chicago Midway

$341Southwest

Sat, Nov 7 - Wed, Nov 11

5:55 am - 7:25 pmDSM Des Moines-MYR Myrtle Beach Intl

12h 30m2 stops Chicago Midway Nashville Intl

1:40 pm - 10:15 pmMYR Myrtle Beach Intl-DSM Des Moines

9h 35m2 stops Nashville Intl Chicago Midway

$350Southwest

Mon, Jan 11 - Fri, Jan 15

8:25 pm - 11:44 amDSM Des Moines-MYR Myrtle Beach Intl

38h 19m2 stops Denver Intl Tampa

2:42 pm - 5:02 pmMYR Myrtle Beach Intl-DSM Des Moines

27h 20m1 stop Fort Lauderdale

$384Multiple Airlines

Mon, Oct 12 - Wed, Oct 21

8:00 am - 3:16 pmDSM Des Moines-MYR Myrtle Beach Intl

6h 16m1 stop Chicago O'Hare Intl

5:00 pm - 9:23 pmMYR Myrtle Beach Intl-DSM Des Moines

5h 23m1 stop Chicago O'Hare Intl

$421United Airlines

Mon, Oct 12 - Wed, Oct 21

Cheap last minute flights

Enter your travel dates to find the best prices.

5:45 am - 1:33 pmDSM Des Moines-MYR Myrtle Beach Intl

6h 48m1 stop Atlanta Hartsfield-Jackson

6:58 pm - 10:33 pmMYR Myrtle Beach Intl-DSM Des Moines

4h 35m1 stop Atlanta Hartsfield-Jackson

$662Delta

Wed, Sep 30 - Wed, Oct 7

6:00 am - 12:22 pmDSM Des Moines-MYR Myrtle Beach Intl

5h 22m1 stop Philadelphia

6:30 am - 1:50 pmMYR Myrtle Beach Intl-DSM Des Moines

8h 20m2 stops Charlotte Douglas Washington, D.C. Reagan-National

$693American Airlines

Wed, Sep 30 - Wed, Oct 7

6:00 am - 4:55 pmDSM Des Moines-MYR Myrtle Beach Intl

9h 55m2 stops Philadelphia Charlotte Douglas

2:11 pm - 11:07 pmMYR Myrtle Beach Intl-DSM Des Moines

9h 56m2 stops Charlotte Douglas Dallas/Fort Worth

$698American Airlines

Wed, Sep 30 - Wed, Oct 7

6:00 am - 6:03 pmDSM Des Moines-MYR Myrtle Beach Intl

11h 03m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

10:52 am - 2:09 pmMYR Myrtle Beach Intl-DSM Des Moines

4h 17m1 stop Atlanta Hartsfield-Jackson

$713Delta

Wed, Sep 30 - Wed, Oct 7

1:30 pm - 9:08 pmDSM Des Moines-MYR Myrtle Beach Intl

6h 38m1 stop Charlotte Douglas

7:15 am - 10:19 amMYR Myrtle Beach Intl-DSM Des Moines

4h 04m1 stop Charlotte Douglas

$807American Airlines

Thu, Oct 1 - Sun, Oct 4

6:00 am - 1:33 pmDSM Des Moines-MYR Myrtle Beach Intl

6h 33m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

11:27 am - 10:33 pmMYR Myrtle Beach Intl-DSM Des Moines

12h 06m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

$909Delta

Wed, Sep 30 - Wed, Oct 7

6:00 am - 6:03 pmDSM Des Moines-MYR Myrtle Beach Intl

11h 03m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

10:52 am - 2:09 pmMYR Myrtle Beach Intl-DSM Des Moines

4h 17m1 stop Atlanta Hartsfield-Jackson

$917Delta

Wed, Sep 30 - Wed, Oct 7

6:00 am - 6:12 pmDSM Des Moines-MYR Myrtle Beach Intl

11h 12m2 stops Chicago O'Hare Intl Newark

10:23 am - 10:15 pmMYR Myrtle Beach Intl-DSM Des Moines

12h 52m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

$922United Airlines

Wed, Sep 30 - Wed, Oct 7

8:00 am - 9:42 amDSM Des Moines-MYR Myrtle Beach Intl

24h 42m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Newark

12:30 pm - 11:35 pmMYR Myrtle Beach Intl-DSM Des Moines

12h 05m2 stops Newark Chicago O'Hare Intl

$982United Airlines

Wed, Sep 30 - Wed, Oct 7

8:00 am - 9:42 amDSM Des Moines-MYR Myrtle Beach Intl

24h 42m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Newark

12:30 pm - 11:35 pmMYR Myrtle Beach Intl-DSM Des Moines

12h 05m2 stops Newark Chicago O'Hare Intl

$1,032United Airlines

Wed, Sep 30 - Wed, Oct 7

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American Airlines flights from Des Moines to Myrtle Beach

Our best American Airlines deals on Des Moines to Myrtle Beach flight tickets

American Airlines

Nov 7

DSM6:00 amDes Moines

5h 56m

1 stop

MYR12:56 pmMyrtle Beach Intl

Nov 11

MYR5:03 pmMyrtle Beach Intl

7h 23m

1 stop

DSM11:26 pmDes Moines

$325

American Airlines

Nov 7

DSM6:00 amDes Moines

5h 56m

1 stop

MYR12:56 pmMyrtle Beach Intl

Nov 11

MYR6:12 amMyrtle Beach Intl

8h 16m

2 stops

DSM1:28 pmDes Moines

$367

American Airlines

Oct 17

DSM4:12 pmDes Moines

5h 40m

1 stop

MYR10:52 pmMyrtle Beach Intl

Oct 31

MYR6:30 amMyrtle Beach Intl

8h 00m

2 stops

DSM1:30 pmDes Moines

$370

Southwest flights from Des Moines to Myrtle Beach

Our best Southwest deals on Des Moines to Myrtle Beach flight tickets

Southwest

Nov 7

DSM5:20 amDes Moines

11h 00m

2 stops

MYR5:20 pmMyrtle Beach Intl

Nov 11

MYR3:25 pmMyrtle Beach Intl

7h 40m

2 stops

DSM10:05 pmDes Moines

$341

Southwest

Jan 11

DSM5:55 amDes Moines

12h 30m

2 stops

MYR7:25 pmMyrtle Beach Intl

Jan 15

MYR1:40 pmMyrtle Beach Intl

9h 35m

2 stops

DSM10:15 pmDes Moines

$350

Southwest

Dec 3

DSM6:00 amDes Moines

11h 25m

2 stops

MYR6:25 pmMyrtle Beach Intl

Dec 7

MYR3:25 pmMyrtle Beach Intl

7h 35m

2 stops

DSM10:00 pmDes Moines

$359

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Sat 10/17

4:12 pm-10:52 pm

1 stop5h 40m

Myrtle Beach Intl

Sat 10/31

4:57 pm-11:07 pm

1 stop7h 10m

$325

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Sat 11/7

6:00 am-12:56 pm

1 stop5h 56m

Myrtle Beach Intl

Wed 11/11

5:03 pm-11:26 pm

1 stop7h 23m

$325

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Wed 12/2

2:58 pm-10:47 pm

1 stop6h 49m

Myrtle Beach Intl

Tue 12/8

6:00 am-10:49 am

1 stop5h 49m

$325

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Wed 12/2

2:58 pm-10:47 pm

1 stop6h 49m

Myrtle Beach Intl

Mon 12/7

2:18 pm-6:06 pm

1 stop4h 48m

$325

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Thu 12/3

3:31 pm-10:34 pm

1 stop6h 03m

Myrtle Beach Intl

Mon 12/7

6:12 am-10:10 am

1 stop4h 58m

$325

Quickest round-trip

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Mon 1/11

5:15 pm-10:25 pm

1 stop4h 10m

Myrtle Beach Intl

Fri 1/15

6:00 am-10:18 am

1 stop5h 18m

$334

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Sat 11/7

5:20 am-5:20 pm

2 stops11h 00m

Myrtle Beach Intl

Wed 11/11

3:25 pm-10:05 pm

2 stops7h 40m

$341

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Mon 1/11

5:55 am-7:25 pm

2 stops12h 30m

Myrtle Beach Intl

Fri 1/15

1:40 pm-10:15 pm

2 stops9h 35m

$350

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Mon 10/12

8:25 pm-11:44 am

2 stops38h 19m

Myrtle Beach Intl

Wed 10/21

2:42 pm-5:02 pm

1 stop27h 20m

$384

Des MoinesMyrtle Beach

DSM Des Moines - MYR Myrtle Beach Intl

DSMMYR

Des Moines

Mon 10/12

8:00 am-3:16 pm

1 stop6h 16m

Myrtle Beach Intl

Wed 10/21

5:00 pm-9:23 pm

1 stop5h 23m

$421

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Des Moines and Myrtle Beach?

Prices are currently low for flights on this route.

Typical prices usually range from $346 to $416.
The lowest price recently found on this route was $325.

What is the cheapest month to fly to Myrtle Beach?

In general, January is the cheapest month to fly from Des Moines to Myrtle Beach. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $293. If you are unable to visit Myrtle Beach during the month of January, then departing from Des Moines during the month November is also very affordable. Most momondo users find prices during this month for around $316.

Can stopping save me money on Des Moines to Myrtle Beach flights?

You could potentially save up to 2% on your flight if you consider stops on a Des Moines to Myrtle Beach flight.

When to book flights from Des Moines to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Myrtle Beach (DSM to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Myrtle Beach

Best Price Found	$163
Fastest flight time	4h 10m
Direct flights	None

The best one-way flight to Myrtle Beach from Des Moines in the past 72 hours is $163. The best round-trip flight deal from Des Moines to Myrtle Beach found on momondo in the last 72 hours is $325.

The fastest flight from Des Moines to Myrtle Beach takes 4h 10m

There are no direct flights from Des Moines to Myrtle Beach. There are no popular flight routes from Des Moines to Myrtle Beach.

Search flight deals

Frequently asked questions about flying from Des Moines to Myrtle Beach

How far is Des Moines to Myrtle Beach Intl by plane?
A flight from Des Moines to Myrtle Beach Intl will travel around 970.9 mi. Flights usually cover this in 4h 10m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Des Moines Airport to Myrtle Beach Intl Airport?
Prices for flights from Des Moines Airport to Myrtle Beach Intl Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Des Moines Airport to Myrtle Beach Intl Airport?
As of September 2026, there are 3 operators available to choose from for flights from Des Moines Airport to Myrtle Beach Intl Airport.
How old do you have to be to fly from Des Moines Airport to Myrtle Beach Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Myrtle Beach Intl Airport.
What documentation or ID do you need to fly to Myrtle Beach Intl Airport?
The travel and health documents you'll need for your trip to Myrtle Beach Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Myrtle Beach Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Myrtle Beach?
Based on momondo bookings for flights between Des Moines and Myrtle Beach, the leading airline is American Airlines, making up 66% of the total bookings. Other popular airlines include Delta with 21% and Southwest with 13%.

Best airlines flying from Des Moines to Myrtle Beach

Compare and see reviews for airlines that fly from Des Moines to Myrtle Beach with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $292	Free Cancellation	Rating 7.0 12,099 reviews	Search American Airlines flights
Delta	PriceFrom $324	Free Cancellation	Rating 7.8 8,610 reviews	Search Delta flights
Southwest	PriceFrom $344	Free Cancellation	Rating 8.0 4,201 reviews	Search Southwest flights

North Myrtle Beach

Pawleys Island

Surfside Beach

Conway

Ocean Isle Beach

Murrells Inlet

Sunset Beach

Garden City Beach

Little River

Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Myrtle Beach?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Myrtle Beach. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Myrtle Beach from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Myrtle Beach?

Once all potential Des Moines to Myrtle Beach flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Myrtle Beach right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Myrtle Beach from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Charleston Airport

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Cheap flights from Des Moines to Myrtle Beach from $163

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Myrtle Beach departing on 12/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Des Moines to Myrtle Beach

Our best American Airlines deals on Des Moines to Myrtle Beach flight tickets

Southwest flights from Des Moines to Myrtle Beach

Our best Southwest deals on Des Moines to Myrtle Beach flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Des Moines to Myrtle Beach

What is the typical price of a round-trip flight between Des Moines and Myrtle Beach?

What is the cheapest month to fly to Myrtle Beach?

Can stopping save me money on Des Moines to Myrtle Beach flights?

What is the cheapest airline that flies from Des Moines to Myrtle Beach Intl?

What airlines fly to Myrtle Beach?

When to book flights from Des Moines to Myrtle Beach

Cheap Des Moines to Myrtle Beach (DSM to MYR) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Des Moines to Myrtle Beach

Best airlines flying from Des Moines to Myrtle Beach

Compare and see reviews for airlines that fly from Des Moines to Myrtle Beach with momondo

Traveling to a place near Myrtle Beach?

Why use momondo?

An easier way to manage your Myrtle Beach trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing South Carolina

Fly your favorite airline to Myrtle Beach

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Myrtle Beach

List of cabin classes available on flights landing in Myrtle Beach. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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