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Cheap flights from Columbia, Missouri to Los Angeles from $299

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Los Angeles departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia, Missouri to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:15 am - 8:50 pm
COU
-
SNA
11h 35m
2 stops
United Airlines Logo
10:51 am - 9:33 pm
SNA
-
COU
8h 42m
1 stop
$334United Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
11:15 am - 8:50 pm
COU
-
SNA
11h 35m
2 stops
United Airlines Logo
11:10 am - 9:33 pm
SNA
-
COU
8h 23m
2 stops
$339United Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
9:02 am - 3:03 pm
COU
-
SNA
8h 01m
1 stop
United Airlines Logo
6:39 pm - 10:57 am
SNA
-
COU
14h 18m
2 stops
$364United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
9:05 am - 8:50 pm
COU
-
SNA
13h 45m
2 stops
United Airlines Logo
1:27 pm - 8:20 pm
SNA
-
COU
4h 53m
1 stop
$368United Airlines
Sat, Mar 7 - Tue, Mar 10
United Airlines Logo
8:00 am - 3:03 pm
COU
-
SNA
9h 03m
2 stops
United Airlines Logo
6:39 pm - 10:57 am
SNA
-
COU
14h 18m
2 stops
$369United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
9:02 am - 1:18 pm
COU
-
SNA
6h 16m
1 stop
United Airlines Logo
11:10 am - 9:03 pm
SNA
-
COU
7h 53m
1 stop
$383United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
11:30 am - 8:48 pm
COU
-
SNA
11h 18m
2 stops
United Airlines Logo
1:21 pm - 9:03 pm
SNA
-
COU
5h 42m
1 stop
$389United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
11:30 am - 8:48 pm
COU
-
SNA
11h 18m
2 stops
United Airlines Logo
6:39 pm - 10:55 am
SNA
-
COU
14h 16m
2 stops
$394United Airlines
Sat, Apr 18 - Tue, Apr 21
United Airlines Logo
3:10 pm - 10:30 pm
COU
-
SNA
9h 20m
1 stop
United Airlines Logo
10:45 am - 9:58 pm
SNA
-
COU
9h 13m
1 stop
$408United Airlines
Wed, May 6 - Sat, May 9
American Airlines Logo
6:00 am - 10:51 am
COU
-
SNA
6h 51m
1 stop
American Airlines Logo
7:45 am - 6:00 pm
SNA
-
COU
8h 15m
1 stop
$412American Airlines
Sat, Mar 7 - Tue, Mar 10

United Airlines flights from Columbia, Missouri to Santa Ana

Our best United Airlines deals on Columbia, Missouri to Santa Ana flight tickets
United Airlines
Feb 21
COU11:15 amColumbia Regional
11h 35m
2 stops
SNA8:50 pmSanta Ana J. Wayne/Orange Cnty
Feb 25
SNA10:51 amSanta Ana J. Wayne/Orange Cnty
8h 42m
1 stop
COU9:33 pmColumbia Regional
$334
United Airlines
Feb 21
COU11:15 amColumbia Regional
11h 35m
2 stops
SNA8:50 pmSanta Ana J. Wayne/Orange Cnty
Feb 25
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
8h 23m
2 stops
COU9:33 pmColumbia Regional
$339
United Airlines
Apr 28
COU9:02 amColumbia Regional
8h 01m
1 stop
SNA3:03 pmSanta Ana J. Wayne/Orange Cnty
May 2
SNA6:39 pmSanta Ana J. Wayne/Orange Cnty
14h 18m
2 stops
COU10:57 amColumbia Regional
$364

American Airlines flights from Columbia, Missouri to Santa Ana

Our best American Airlines deals on Columbia, Missouri to Santa Ana flight tickets
American Airlines
Mar 7
COU6:00 amColumbia Regional
6h 51m
1 stop
SNA10:51 amSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 15m
1 stop
COU6:00 pmColumbia Regional
$412
American Airlines
Mar 7
COU6:00 amColumbia Regional
6h 51m
1 stop
SNA10:51 amSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA12:26 pmSanta Ana J. Wayne/Orange Cnty
8h 14m
2 stops
COU10:40 pmColumbia Regional
$418
American Airlines
Mar 7
COU12:33 pmColumbia Regional
8h 58m
2 stops
SNA7:31 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA12:26 pmSanta Ana J. Wayne/Orange Cnty
8h 14m
2 stops
COU10:40 pmColumbia Regional
$494

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Columbia, Missouri to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 2/21

11:15 am-8:50 pm

2 stops11h 35m

Santa Ana J. Wayne/Orange Cnty

Wed 2/25

10:51 am-9:33 pm

1 stop8h 42m

$334

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 2/21

11:15 am-8:50 pm

2 stops11h 35m

Santa Ana J. Wayne/Orange Cnty

Wed 2/25

11:10 am-9:33 pm

2 stops8h 23m

$339

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 4/28

9:02 am-3:03 pm

1 stop8h 01m

Santa Ana J. Wayne/Orange Cnty

Sat 5/2

6:39 pm-10:57 am

2 stops14h 18m

$364

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 3/7

9:05 am-8:50 pm

2 stops13h 45m

Santa Ana J. Wayne/Orange Cnty

Tue 3/10

1:27 pm-8:20 pm

1 stop4h 53m

$368

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 4/28

8:00 am-3:03 pm

2 stops9h 03m

Santa Ana J. Wayne/Orange Cnty

Sat 5/2

6:39 pm-10:57 am

2 stops14h 18m

$369

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 4/18

9:02 am-1:18 pm

1 stop6h 16m

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

11:10 am-9:03 pm

1 stop7h 53m

$383

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 4/18

11:30 am-8:48 pm

2 stops11h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

1:21 pm-9:03 pm

1 stop5h 42m

$389

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 4/18

11:30 am-8:48 pm

2 stops11h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

6:39 pm-10:55 am

2 stops14h 16m

$394

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 5/6

3:10 pm-10:30 pm

1 stop9h 20m

Santa Ana J. Wayne/Orange Cnty

Sat 5/9

10:45 am-9:58 pm

1 stop9h 13m

$408

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 3/7

6:00 am-10:51 am

1 stop6h 51m

Santa Ana J. Wayne/Orange Cnty

Tue 3/10

7:45 am-6:00 pm

1 stop8h 15m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Columbia, Missouri to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Columbia Regional to Santa Ana J. Wayne/Orange Cnty?

United Airlines is the most popular carrier operating from Columbia Regional to Santa Ana J. Wayne/Orange Cnty

When to book flights from Columbia, Missouri to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Santa Ana (COU to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Santa Ana

Fastest flight time

6h 16m

Direct flights

None
The fastest flight from Columbia, Missouri to Santa Ana takes 6h 16m
There are no direct flights from Columbia, Missouri to Santa Ana. There are no popular flight routes from Columbia, Missouri to Santa Ana.
Search flight deals

  • How far is Columbia Regional to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1459.4 mi between Columbia Regional and Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 6h 16m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to Santa Ana?

Best airlines flying from Columbia, Missouri to Santa Ana

Compare and see reviews for airlines that fly from Columbia, Missouri to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $421Free CancellationRating
7.2
11,243 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

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Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Santa Ana?

Once all potential Columbia to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbia to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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