Cheap flights from Columbia, Missouri to Los Angeles from $358

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Los Angeles departing on 1/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:17 am - 6:41 pm
COU
-
SNA
9h 24m1 stop
United Airlines Logo
10:51 am - 9:37 pm
SNA
-
COU
8h 46m1 stop
$358United Airlines
Sat, Jan 10 - Tue, Jan 13
United Airlines Logo
11:17 am - 9:19 pm
COU
-
SNA
12h 02m2 stops
United Airlines Logo
11:05 am - 8:33 pm
SNA
-
COU
7h 28m1 stop
$364United Airlines
Sat, Jan 10 - Tue, Jan 13
United Airlines Logo
11:17 am - 9:19 pm
COU
-
SNA
12h 02m2 stops
United Airlines Logo
7:00 am - 9:37 pm
SNA
-
COU
12h 37m2 stops
$369United Airlines
Sat, Jan 10 - Tue, Jan 13
United Airlines Logo
3:10 pm - 10:24 pm
COU
-
SNA
9h 14m1 stop
United Airlines Logo
1:17 pm - 8:33 pm
SNA
-
COU
5h 16m1 stop
$383United Airlines
Fri, Jan 9 - Wed, Jan 14

United Airlines flights from Columbia, Missouri to Santa Ana, California

Our best United Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
United Airlines
Jan 10
COU11:17 amColumbia Regional
9h 24m
1 stop
SNA6:41 pmSanta Ana J. Wayne/Orange Cnty
Jan 13
SNA10:51 amSanta Ana J. Wayne/Orange Cnty
8h 46m
1 stop
COU9:37 pmColumbia Regional
United Airlines
Jan 10
COU11:17 amColumbia Regional
12h 02m
2 stops
SNA9:19 pmSanta Ana J. Wayne/Orange Cnty
Jan 13
SNA11:05 amSanta Ana J. Wayne/Orange Cnty
7h 28m
1 stop
COU8:33 pmColumbia Regional
United Airlines
Jan 10
COU11:17 amColumbia Regional
12h 02m
2 stops
SNA9:19 pmSanta Ana J. Wayne/Orange Cnty
Jan 13
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
12h 37m
2 stops
COU9:37 pmColumbia Regional

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 1/10

11:17 am-6:41 pm

1 stop9h 24m

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

10:51 am-9:37 pm

1 stop8h 46m

$358

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 1/10

11:17 am-9:19 pm

2 stops12h 02m

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

11:05 am-8:33 pm

1 stop7h 28m

$364

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 1/10

11:17 am-9:19 pm

2 stops12h 02m

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

7:00 am-9:37 pm

2 stops12h 37m

$369

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 1/9

3:10 pm-10:24 pm

1 stop9h 14m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

1:17 pm-8:33 pm

1 stop5h 16m

$383

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 1/1

8:45 am-1:06 pm

1 stop6h 21m

$463

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 1/1

3:10 pm-9:38 am

2 stops20h 28m

$578

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 1/1

8:05 am-8:46 pm

3 stops14h 41m

$1,408

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Columbia, Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Columbia, Missouri to Santa Ana, California is on a Thursday. Travelers who choose to depart for Santa Ana, California on a Thursday will often find tickets for as low as $389. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $609.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the afternoon is the cheapest time of day to fly from Columbia, Missouri to Santa Ana, California when you can find flight prices for as low as $416. Flying to Santa Ana, California in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the morning when prices are around $695.

When to book flights from Columbia, Missouri to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Santa Ana, California (COU to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Santa Ana, California

Fastest flight time

9h 24m

Direct flights

None
The fastest flight from Columbia, Missouri to Santa Ana, California takes 9h 24m
There are no direct flights from Columbia, Missouri to Santa Ana, California. There are no popular flight routes from Columbia, Missouri to Santa Ana, California.
  • How far is Columbia Regional to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1459.4 mi between Columbia Regional and Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 9h 24m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to Santa Ana, California?

Best airlines flying from Columbia, Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Columbia, Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $392Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Santa Ana?

Once all potential Columbia to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbia to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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1 adult
Wed 1/14
Wed 1/21

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