Cheap flights from Columbia, Missouri to Los Angeles from $293

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Los Angeles departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Columbia, Missouri to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:00 am - 2:58 pmCOU-SNA
7h 58m1 stop
United Airlines Logo
6:45 am - 5:11 pmSNA-COU
8h 26m1 stop
$293United Airlines
Find Deal
Tue, Nov 11 - Sat, Dec 13
United Airlines Logo
8:00 am - 5:48 pmCOU-SNA
11h 48m2 stops
United Airlines Logo
10:40 am - 9:22 pmSNA-COU
8h 42m1 stop
$299United Airlines
Find Deal
Tue, Nov 11 - Sat, Dec 13
United Airlines Logo
8:00 am - 5:48 pmCOU-SNA
11h 48m2 stops
United Airlines Logo
8:55 am - 9:22 pmSNA-COU
10h 27m2 stops
$304United Airlines
Find Deal
Tue, Nov 11 - Sat, Dec 13
United Airlines Logo
9:00 am - 1:06 pmCOU-SNA
6h 06m1 stop
United Airlines Logo
6:45 am - 5:11 pmSNA-COU
8h 26m1 stop
$338United Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
United Airlines Logo
9:00 am - 6:47 pmCOU-SNA
11h 47m2 stops
United Airlines Logo
6:45 am - 5:11 pmSNA-COU
8h 26m1 stop
$344United Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
United Airlines Logo
9:00 am - 2:58 pmCOU-SNA
7h 58m1 stop
United Airlines Logo
10:40 am - 9:22 pmSNA-COU
8h 42m1 stop
$363United Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
United Airlines Logo
9:00 am - 6:47 pmCOU-SNA
11h 47m2 stops
United Airlines Logo
6:45 am - 5:11 pmSNA-COU
8h 26m1 stop
$369United Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
United Airlines Logo
9:00 am - 6:47 pmCOU-SNA
11h 47m2 stops
United Airlines Logo
8:55 am - 9:22 pmSNA-COU
10h 27m2 stops
$384United Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
6:32 am - 12:43 pmCOU-SNA
8h 11m1 stop
American Airlines Logo
9:30 am - 5:43 pmSNA-COU
6h 13m1 stop
$437American Airlines
Find Deal
Tue, Nov 11 - Sat, Dec 13
American Airlines Logo
6:05 pm - 10:40 pmCOU-SNA
6h 35m1 stop
American Airlines Logo
7:45 am - 9:59 pmSNA-COU
12h 14m1 stop
$478American Airlines
Find Deal
Fri, Jan 2 - Mon, Jan 5

United Airlines flights from Columbia, Missouri to Santa Ana, California

Our best United Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
United Airlines
Nov 11
COU9:00 amColumbia Regional
7h 58m
1 stop
SNA2:58 pmSanta Ana J. Wayne/Orange Cnty
Dec 13
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 26m
1 stop
COU5:11 pmColumbia Regional
United Airlines
Nov 11
COU8:00 amColumbia Regional
11h 48m
2 stops
SNA5:48 pmSanta Ana J. Wayne/Orange Cnty
Dec 13
SNA10:40 amSanta Ana J. Wayne/Orange Cnty
8h 42m
1 stop
COU9:22 pmColumbia Regional
United Airlines
Nov 11
COU8:00 amColumbia Regional
11h 48m
2 stops
SNA5:48 pmSanta Ana J. Wayne/Orange Cnty
Dec 13
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
10h 27m
2 stops
COU9:22 pmColumbia Regional

American Airlines flights from Columbia, Missouri to Santa Ana, California

Our best American Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
American Airlines
Nov 11
COU6:32 amColumbia Regional
8h 11m
1 stop
SNA12:43 pmSanta Ana J. Wayne/Orange Cnty
Dec 13
SNA9:30 amSanta Ana J. Wayne/Orange Cnty
6h 13m
1 stop
COU5:43 pmColumbia Regional
American Airlines
Jan 2
COU6:05 pmColumbia Regional
6h 35m
1 stop
SNA10:40 pmSanta Ana J. Wayne/Orange Cnty
Jan 5
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
12h 14m
1 stop
COU9:59 pmColumbia Regional
American Airlines
Oct 31
COU6:01 amColumbia Regional
6h 47m
1 stop
SNA10:48 amSanta Ana J. Wayne/Orange Cnty
Nov 3
SNA11:42 amSanta Ana J. Wayne/Orange Cnty
8h 13m
1 stop
COU9:55 pmColumbia Regional

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 11/11

9:00 am-2:58 pm

1 stop7h 58m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

6:45 am-5:11 pm

1 stop8h 26m

$293

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 11/11

8:00 am-5:48 pm

2 stops11h 48m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

10:40 am-9:22 pm

1 stop8h 42m

$299

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 11/11

8:00 am-5:48 pm

2 stops11h 48m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

8:55 am-9:22 pm

2 stops10h 27m

$304

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 12/10

9:00 am-1:06 pm

1 stop6h 06m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

6:45 am-5:11 pm

1 stop8h 26m

$338

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 12/10

9:00 am-6:47 pm

2 stops11h 47m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

6:45 am-5:11 pm

1 stop8h 26m

$344

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 12/10

9:00 am-2:58 pm

1 stop7h 58m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

10:40 am-9:22 pm

1 stop8h 42m

$363

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 12/10

9:00 am-6:47 pm

2 stops11h 47m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

6:45 am-5:11 pm

1 stop8h 26m

$369

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 12/10

9:00 am-6:47 pm

2 stops11h 47m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

8:55 am-9:22 pm

2 stops10h 27m

$384

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 11/11

6:32 am-12:43 pm

1 stop8h 11m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

9:30 am-5:43 pm

1 stop6h 13m

$437

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 1/2

6:05 pm-10:40 pm

1 stop6h 35m

Santa Ana J. Wayne/Orange Cnty

Mon 1/5

7:45 am-9:59 pm

1 stop12h 14m

$478

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Columbia, Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Columbia, Missouri to Santa Ana, California is on a Thursday. Travelers who choose to depart for Santa Ana, California on a Thursday will often find tickets for as low as $389. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $609.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the afternoon is the cheapest time of day to fly from Columbia, Missouri to Santa Ana, California when you can find flight prices for as low as $416. Flying to Santa Ana, California in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is in the morning when prices are around $695.

When to book flights from Columbia, Missouri to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Santa Ana, California (COU to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Santa Ana, California

Direct flights

None
There are no direct flights from Columbia, Missouri to Santa Ana, California. There are no popular flight routes from Columbia, Missouri to Santa Ana, California.
  • How far is Columbia Regional to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1459.4 mi between Columbia Regional and Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 6h 03m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to Santa Ana, California?

Best airlines flying from Columbia, Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Columbia, Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $421Free CancellationRating
7.2
11,030 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Santa Ana?

Once all potential Columbia to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbia to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

An easier way to manage your Santa Ana, California trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 11/28
Fri 12/5

Find better results for your trip to the United States