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Cheap flights from Columbia, Missouri to Los Angeles from $316

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Los Angeles departing on 6/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia, Missouri to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:00 pm - 5:33 pm
COU
-
SNA
7h 33m
1 stop
American Airlines Logo
11:42 am - 9:55 pm
SNA
-
COU
8h 13m
1 stop
$318American Airlines
Sat, Oct 31 - Sat, Nov 7
American Airlines Logo
2:42 pm - 9:41 pm
COU
-
SNA
8h 59m
2 stops
American Airlines Logo
8:30 am - 5:28 pm
SNA
-
COU
6h 58m
1 stop
$324American Airlines
Sat, Oct 31 - Sat, Nov 7
United Airlines Logo
10:46 am - 6:51 pm
COU
-
SNA
10h 05m
1 stop
United Airlines Logo
11:10 am - 8:59 pm
SNA
-
COU
7h 49m
1 stop
$328United Airlines
Sat, Aug 22 - Tue, Aug 25
American Airlines Logo
12:00 pm - 5:56 pm
COU
-
SNA
7h 56m
2 stops
American Airlines Logo
6:45 am - 5:28 pm
SNA
-
COU
8h 43m
2 stops
$329American Airlines
Sat, Oct 31 - Sat, Nov 7
United Airlines Logo
8:00 am - 5:29 pm
COU
-
SNA
11h 29m
2 stops
United Airlines Logo
11:10 am - 8:59 pm
SNA
-
COU
7h 49m
1 stop
$334United Airlines
Sat, Aug 22 - Tue, Aug 25
United Airlines Logo
10:46 am - 5:29 pm
COU
-
SNA
8h 43m
2 stops
United Airlines Logo
11:10 am - 10:35 pm
SNA
-
COU
9h 25m
2 stops
$339United Airlines
Sat, Aug 22 - Tue, Aug 25
American Airlines Logo
11:48 am - 5:29 pm
COU
-
SNA
7h 41m
1 stop
American Airlines Logo
1:34 pm - 10:27 pm
SNA
-
COU
6h 53m
1 stop
$384American Airlines
Sat, Aug 22 - Tue, Aug 25
American Airlines Logo
11:48 am - 5:29 pm
COU
-
SNA
7h 41m
1 stop
American Airlines Logo
9:45 am - 9:21 pm
SNA
-
COU
9h 36m
2 stops
$389American Airlines
Sat, Aug 22 - Tue, Aug 25
American Airlines Logo
6:00 am - 3:32 pm
COU
-
SNA
11h 32m
2 stops
American Airlines Logo
9:45 am - 10:06 pm
SNA
-
COU
10h 21m
2 stops
$415American Airlines
Sat, Aug 22 - Tue, Aug 25
United Airlines Logo
11:30 am - 9:50 pm
COU
-
SNA
12h 20m
2 stops
United Airlines Logo
8:40 am - 9:49 pm
SNA
-
COU
11h 09m
2 stops
$419United Airlines
Wed, Aug 26 - Sat, Aug 29

United Airlines flights from Columbia, Missouri to Santa Ana, California

Our best United Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
United Airlines
Aug 22
COU10:46 amColumbia Regional
10h 05m
1 stop
SNA6:51 pmSanta Ana J. Wayne/Orange Cnty
Aug 25
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
7h 49m
1 stop
COU8:59 pmColumbia Regional
$328
United Airlines
Aug 22
COU8:00 amColumbia Regional
11h 29m
2 stops
SNA5:29 pmSanta Ana J. Wayne/Orange Cnty
Aug 25
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
7h 49m
1 stop
COU8:59 pmColumbia Regional
$334
United Airlines
Aug 22
COU10:46 amColumbia Regional
8h 43m
2 stops
SNA5:29 pmSanta Ana J. Wayne/Orange Cnty
Aug 25
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
9h 25m
2 stops
COU10:35 pmColumbia Regional
$339

American Airlines flights from Columbia, Missouri to Santa Ana, California

Our best American Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
American Airlines
Oct 31
COU12:00 pmColumbia Regional
7h 33m
1 stop
SNA5:33 pmSanta Ana J. Wayne/Orange Cnty
Nov 7
SNA11:42 amSanta Ana J. Wayne/Orange Cnty
8h 13m
1 stop
COU9:55 pmColumbia Regional
$318
American Airlines
Oct 31
COU2:42 pmColumbia Regional
8h 59m
2 stops
SNA9:41 pmSanta Ana J. Wayne/Orange Cnty
Nov 7
SNA8:30 amSanta Ana J. Wayne/Orange Cnty
6h 58m
1 stop
COU5:28 pmColumbia Regional
$324
American Airlines
Oct 31
COU12:00 pmColumbia Regional
7h 56m
2 stops
SNA5:56 pmSanta Ana J. Wayne/Orange Cnty
Nov 7
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 43m
2 stops
COU5:28 pmColumbia Regional
$329

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from Columbia, Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 10/31

12:00 pm-5:33 pm

1 stop7h 33m

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

11:42 am-9:55 pm

1 stop8h 13m

$318

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 10/31

2:42 pm-9:41 pm

2 stops8h 59m

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

8:30 am-5:28 pm

1 stop6h 58m

$324

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

10:46 am-6:51 pm

1 stop10h 05m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

11:10 am-8:59 pm

1 stop7h 49m

$328

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 10/31

12:00 pm-5:56 pm

2 stops7h 56m

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

6:45 am-5:28 pm

2 stops8h 43m

$329

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

8:00 am-5:29 pm

2 stops11h 29m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

11:10 am-8:59 pm

1 stop7h 49m

$334

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

10:46 am-5:29 pm

2 stops8h 43m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

11:10 am-10:35 pm

2 stops9h 25m

$339
Quickest round-trip

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

11:48 am-5:29 pm

1 stop7h 41m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

1:34 pm-10:27 pm

1 stop6h 53m

$384

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

11:48 am-5:29 pm

1 stop7h 41m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

9:45 am-9:21 pm

2 stops9h 36m

$389

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

6:00 am-3:32 pm

2 stops11h 32m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

9:45 am-10:06 pm

2 stops10h 21m

$415

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 8/26

11:30 am-9:50 pm

2 stops12h 20m

Santa Ana J. Wayne/Orange Cnty

Sat 8/29

8:40 am-9:49 pm

2 stops11h 09m

$419

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Columbia, Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbia, Missouri and Santa Ana, California?

What is the cheapest month to fly to Santa Ana, California?

In general, September is the cheapest month to fly from Columbia, Missouri to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of September, then book flights to Santa Ana, California from Columbia, Missouri during January instead. Flights to Santa Ana, California in January, while not as cheap as those in September, still average around $355.

When to book flights from Columbia, Missouri to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Santa Ana, California (COU to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Santa Ana, California

Fastest flight time

7h 42m

Direct flights

None
The fastest flight from Columbia, Missouri to Santa Ana, California takes 7h 42m
There are no direct flights from Columbia, Missouri to Santa Ana, California. There are no popular flight routes from Columbia, Missouri to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Columbia, Missouri to Santa Ana, California

  • How far is Columbia Regional to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1459.4 mi between Columbia Regional and Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 7h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to Santa Ana, California?

Best airlines flying from Columbia, Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Columbia, Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $383Free CancellationRating
7.4
9,692 reviews
Search United Airlines flights
American AirlinesPriceFrom $421Free CancellationRating
7.1
11,669 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Santa Ana?

Once all potential Columbia to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbia to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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