Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Columbia, Missouri to Los Angeles from $328

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Los Angeles departing on 9/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbia, Missouri to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:00 am - 3:12 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
8h 12m1 stop Denver Intl
United Airlines Logo
1:08 pm - 8:39 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
5h 31m1 stop Denver Intl
$328United Airlines
Tue, Sep 1 - Wed, Sep 9
United Airlines Logo
9:01 am - 1:14 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
6h 13m1 stop Denver Intl
United Airlines Logo
1:09 pm - 8:41 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
5h 32m1 stop Denver Intl
$328United Airlines
Sat, Oct 31 - Sat, Nov 7
American Airlines Logo
5:14 pm - 10:29 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
7h 15m1 stop Dallas/Fort Worth
American Airlines Logo
6:45 am - 4:41 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
7h 56m1 stop Dallas/Fort Worth
$328American Airlines
Sat, Oct 31 - Sat, Nov 7
American Airlines Logo
11:46 am - 3:41 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
5h 55m1 stop Dallas/Fort Worth
American Airlines Logo
10:35 am - 8:12 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
7h 37m1 stop Dallas/Fort Worth
$328American Airlines
Tue, Sep 1 - Wed, Sep 9
United Airlines Logo
3:19 pm - 10:26 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
9h 07m1 stop Chicago O'Hare Intl
United Airlines Logo
11:29 am - 8:33 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
7h 04m1 stop Denver Intl
$328United Airlines
Wed, Sep 30 - Sat, Oct 3
United Airlines Logo
9:01 am - 6:44 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
11h 43m2 stops Denver Intl San Francisco
United Airlines Logo
10:47 am - 9:38 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
8h 51m1 stop Chicago O'Hare Intl
$334United Airlines
Sat, Oct 31 - Sat, Nov 7
United Airlines Logo
6:15 am - 11:33 amCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
7h 18m1 stop Chicago O'Hare Intl
United Airlines Logo
8:55 am - 10:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
12h 00m2 stops Denver Intl Chicago O'Hare Intl
$334United Airlines
Tue, Sep 1 - Wed, Sep 9
United Airlines Logo
3:19 pm - 10:26 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
9h 07m1 stop Chicago O'Hare Intl
United Airlines Logo
11:29 am - 10:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
9h 26m2 stops Denver Intl Chicago O'Hare Intl
$334United Airlines
Wed, Sep 30 - Sat, Oct 3
United Airlines Logo
11:20 am - 9:09 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
11h 49m2 stops Chicago O'Hare Intl Denver Intl
United Airlines Logo
9:36 am - 9:38 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
10h 02m2 stops San Francisco Chicago O'Hare Intl
$339United Airlines
Sat, Oct 31 - Sat, Nov 7
United Airlines Logo
9:00 am - 3:30 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
8h 30m2 stops Denver Intl San Francisco
United Airlines Logo
11:10 am - 10:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
9h 45m2 stops Denver Intl Chicago O'Hare Intl
$339United Airlines
Tue, Sep 1 - Wed, Sep 9

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Columbia, Missouri to Santa Ana, California

Our best American Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
American Airlines
Nov 6
COU5:11 pmColumbia Regional
7h 23m
1 stop
SNA10:34 pmSanta Ana J. Wayne/Orange Cnty
Dec 4
SNA11:40 amSanta Ana J. Wayne/Orange Cnty
8h 35m
1 stop
COU10:15 pmColumbia Regional
$363
American Airlines
Aug 29
COU11:46 amColumbia Regional
5h 55m
1 stop
SNA3:41 pmSanta Ana J. Wayne/Orange Cnty
Sep 2
SNA11:20 amSanta Ana J. Wayne/Orange Cnty
7h 59m
1 stop
COU9:19 pmColumbia Regional
$398
American Airlines
Sep 8
COU11:46 amColumbia Regional
7h 43m
1 stop
SNA5:29 pmSanta Ana J. Wayne/Orange Cnty
Sep 15
SNA11:34 amSanta Ana J. Wayne/Orange Cnty
7h 12m
1 stop
COU8:46 pmColumbia Regional
$442

United Airlines flights from Columbia, Missouri to Santa Ana, California

Our best United Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
United Airlines
Sep 1
COU9:00 amColumbia Regional
8h 12m
1 stop
SNA3:12 pmSanta Ana J. Wayne/Orange Cnty
Sep 9
SNA1:08 pmSanta Ana J. Wayne/Orange Cnty
5h 31m
1 stop
COU8:39 pmColumbia Regional
$328
United Airlines
Sep 1
COU6:15 amColumbia Regional
7h 18m
1 stop
SNA11:33 amSanta Ana J. Wayne/Orange Cnty
Sep 9
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
12h 00m
2 stops
COU10:55 pmColumbia Regional
$334
United Airlines
Sep 1
COU9:00 amColumbia Regional
8h 30m
2 stops
SNA3:30 pmSanta Ana J. Wayne/Orange Cnty
Sep 9
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
9h 45m
2 stops
COU10:55 pmColumbia Regional
$339

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Columbia, Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Tue 9/1

9:00 am-3:12 pm

1 stop8h 12m

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

1:08 pm-8:39 pm

1 stop5h 31m

$328
Quickest round-trip

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Sat 10/31

9:01 am-1:14 pm

1 stop6h 13m

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

1:09 pm-8:41 pm

1 stop5h 32m

$328

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Sat 10/31

5:14 pm-10:29 pm

1 stop7h 15m

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

6:45 am-4:41 pm

1 stop7h 56m

$328

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Tue 9/1

11:46 am-3:41 pm

1 stop5h 55m

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

10:35 am-8:12 pm

1 stop7h 37m

$328

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Wed 9/30

3:19 pm-10:26 pm

1 stop9h 07m

Santa Ana J. Wayne/Orange Cnty

Sat 10/3

11:29 am-8:33 pm

1 stop7h 04m

$328

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Sat 10/31

9:01 am-6:44 pm

2 stops11h 43m

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

10:47 am-9:38 pm

1 stop8h 51m

$334

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Tue 9/1

6:15 am-11:33 am

1 stop7h 18m

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

8:55 am-10:55 pm

2 stops12h 00m

$334

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Wed 9/30

3:19 pm-10:26 pm

1 stop9h 07m

Santa Ana J. Wayne/Orange Cnty

Sat 10/3

11:29 am-10:55 pm

2 stops9h 26m

$334

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Sat 10/31

11:20 am-9:09 pm

2 stops11h 49m

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

9:36 am-9:38 pm

2 stops10h 02m

$339

ColumbiaSanta Ana

COU Columbia Regional - SNA Santa Ana J. Wayne/Orange Cnty

COUSNA

Columbia Regional

Tue 9/1

9:00 am-3:30 pm

2 stops8h 30m

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

11:10 am-10:55 pm

2 stops9h 45m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Columbia, Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, October is the cheapest month to fly from Columbia, Missouri to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of October, then book flights to Santa Ana, California from Columbia, Missouri during January instead. Flights to Santa Ana, California in January, while not as cheap as those in October, still average around $383.

When to book flights from Columbia, Missouri to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Santa Ana, California (COU to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Santa Ana, California

Fastest flight time

5h 55m

Direct flights

None
The fastest flight from Columbia, Missouri to Santa Ana, California takes 5h 55m
There are no direct flights from Columbia, Missouri to Santa Ana, California. There are no popular flight routes from Columbia, Missouri to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Columbia, Missouri to Santa Ana, California

  • How far is Columbia Regional to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1459.4 mi between Columbia Regional and Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 5h 55m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to Santa Ana, California?

Best airlines flying from Columbia, Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Columbia, Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $328Free CancellationRating
7.4
10,108 reviews
Search United Airlines flights
American AirlinesPriceFrom $437Free CancellationRating
7.1
11,929 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Santa Ana?

Once all potential Columbia to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbia to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

An easier way to manage your Santa Ana, California trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 9/13
Sun 9/20
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States