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Cheap flights from Columbia, Missouri to Los Angeles from $379

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Los Angeles departing on 8/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbia, Missouri to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:17 pm - 9:45 pm
COU
-
SNA
6h 28m
1 stop
American Airlines Logo
6:45 am - 4:47 pm
SNA
-
COU
8h 02m
1 stop
$379American Airlines
Thu, Aug 13 - Wed, Aug 19
United Airlines Logo
9:00 am - 3:20 pm
COU
-
SNA
8h 20m
1 stop
United Airlines Logo
2:10 pm - 10:55 pm
SNA
-
COU
6h 45m
1 stop
$408United Airlines
Sat, Aug 15 - Sat, Aug 22
United Airlines Logo
11:20 am - 6:51 pm
COU
-
SNA
9h 31m
1 stop
United Airlines Logo
8:00 pm - 10:37 am
SNA
-
COU
12h 37m
2 stops
$414United Airlines
Tue, Sep 22 - Tue, Oct 6
United Airlines Logo
11:20 am - 8:51 pm
COU
-
SNA
11h 31m
2 stops
United Airlines Logo
9:00 am - 10:55 pm
SNA
-
COU
11h 55m
2 stops
$419United Airlines
Tue, Sep 22 - Wed, Oct 7
United Airlines Logo
9:00 am - 3:12 pm
COU
-
SNA
8h 12m
1 stop
United Airlines Logo
11:10 am - 10:55 pm
SNA
-
COU
9h 45m
2 stops
$443United Airlines
Thu, Aug 13 - Wed, Aug 19
American Airlines Logo
5:19 pm - 10:24 pm
COU
-
SNA
7h 05m
1 stop
American Airlines Logo
2:24 pm - 10:20 pm
SNA
-
COU
5h 56m
1 stop
$467American Airlines
Tue, Jul 14 - Sat, Jul 18
United Airlines Logo
3:11 pm - 10:25 pm
COU
-
SNA
9h 14m
1 stop
United Airlines Logo
2:10 pm - 10:55 pm
SNA
-
COU
6h 45m
1 stop
$469United Airlines
Tue, Aug 11 - Sat, Aug 22
United Airlines Logo
9:00 am - 3:20 pm
COU
-
SNA
8h 20m
1 stop
United Airlines Logo
8:55 am - 10:55 pm
SNA
-
COU
12h 00m
2 stops
$474United Airlines
Sat, Aug 15 - Fri, Aug 21
United Airlines Logo
11:19 am - 8:51 pm
COU
-
SNA
11h 32m
2 stops
United Airlines Logo
9:00 am - 10:55 pm
SNA
-
COU
11h 55m
2 stops
$479United Airlines
Sat, Sep 26 - Sat, Oct 3
United Airlines Logo
9:00 am - 3:12 pm
COU
-
SNA
8h 12m
1 stop
United Airlines Logo
11:10 am - 10:55 pm
SNA
-
COU
9h 45m
2 stops
$486United Airlines
Thu, Aug 13 - Wed, Aug 19

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American Airlines flights from Columbia, Missouri to Santa Ana, California

Our best American Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
American Airlines
Aug 13
COU5:17 pmColumbia Regional
6h 28m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
Aug 19
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 02m
1 stop
COU4:47 pmColumbia Regional
$379
American Airlines
Aug 12
COU11:46 amColumbia Regional
7h 43m
1 stop
SNA5:29 pmSanta Ana J. Wayne/Orange Cnty
Aug 21
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 02m
1 stop
COU4:47 pmColumbia Regional
$522
American Airlines
Sep 24
COU6:26 pmColumbia Regional
5h 53m
1 stop
SNA10:19 pmSanta Ana J. Wayne/Orange Cnty
Oct 6
SNA12:01 pmSanta Ana J. Wayne/Orange Cnty
7h 52m
1 stop
COU9:53 pmColumbia Regional
$529

United Airlines flights from Columbia, Missouri to Santa Ana, California

Our best United Airlines deals on Columbia, Missouri to Santa Ana, California flight tickets
United Airlines
Aug 15
COU9:00 amColumbia Regional
8h 20m
1 stop
SNA3:20 pmSanta Ana J. Wayne/Orange Cnty
Aug 22
SNA2:10 pmSanta Ana J. Wayne/Orange Cnty
6h 45m
1 stop
COU10:55 pmColumbia Regional
$408
United Airlines
Sep 22
COU11:20 amColumbia Regional
11h 24m
2 stops
SNA8:44 pmSanta Ana J. Wayne/Orange Cnty
Oct 7
SNA2:26 pmSanta Ana J. Wayne/Orange Cnty
6h 29m
1 stop
COU10:55 pmColumbia Regional
$414
United Airlines
Sep 22
COU6:15 amColumbia Regional
13h 14m
2 stops
SNA5:29 pmSanta Ana J. Wayne/Orange Cnty
Oct 6
SNA8:00 pmSanta Ana J. Wayne/Orange Cnty
12h 37m
2 stops
COU10:37 amColumbia Regional
$419

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Columbia, Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 8/13

5:17 pm-9:45 pm

1 stop6h 28m

Santa Ana J. Wayne/Orange Cnty

Wed 8/19

6:45 am-4:47 pm

1 stop8h 02m

$379

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/15

9:00 am-3:20 pm

1 stop8h 20m

Santa Ana J. Wayne/Orange Cnty

Sat 8/22

2:10 pm-10:55 pm

1 stop6h 45m

$408

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 9/22

11:20 am-6:51 pm

1 stop9h 31m

Santa Ana J. Wayne/Orange Cnty

Tue 10/6

8:00 pm-10:37 am

2 stops12h 37m

$414

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 9/22

11:20 am-8:51 pm

2 stops11h 31m

Santa Ana J. Wayne/Orange Cnty

Wed 10/7

9:00 am-10:55 pm

2 stops11h 55m

$419

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 8/13

9:00 am-3:12 pm

1 stop8h 12m

Santa Ana J. Wayne/Orange Cnty

Wed 8/19

11:10 am-10:55 pm

2 stops9h 45m

$443
Quickest round-trip

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 7/14

5:19 pm-10:24 pm

1 stop7h 05m

Santa Ana J. Wayne/Orange Cnty

Sat 7/18

2:24 pm-10:20 pm

1 stop5h 56m

$467

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 8/11

3:11 pm-10:25 pm

1 stop9h 14m

Santa Ana J. Wayne/Orange Cnty

Sat 8/22

2:10 pm-10:55 pm

1 stop6h 45m

$469

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/15

9:00 am-3:20 pm

1 stop8h 20m

Santa Ana J. Wayne/Orange Cnty

Fri 8/21

8:55 am-10:55 pm

2 stops12h 00m

$474

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 9/26

11:19 am-8:51 pm

2 stops11h 32m

Santa Ana J. Wayne/Orange Cnty

Sat 10/3

9:00 am-10:55 pm

2 stops11h 55m

$479

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 8/13

9:00 am-3:12 pm

1 stop8h 12m

Santa Ana J. Wayne/Orange Cnty

Wed 8/19

11:10 am-10:55 pm

2 stops9h 45m

$486

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Los Angeles from

How to get the cheapest flight ticket from Columbia, Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, September is the cheapest month to fly from Columbia, Missouri to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of September, then book flights to Santa Ana, California from Columbia, Missouri during January instead. Flights to Santa Ana, California in January, while not as cheap as those in September, still average around $383.

When to book flights from Columbia, Missouri to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Santa Ana, California (COU to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Santa Ana, California

Fastest flight time

7h 43m

Direct flights

None
The fastest flight from Columbia, Missouri to Santa Ana, California takes 7h 43m
There are no direct flights from Columbia, Missouri to Santa Ana, California. There are no popular flight routes from Columbia, Missouri to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Columbia, Missouri to Santa Ana, California

  • How far is Columbia Regional to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1459.4 mi between Columbia Regional and Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 7h 43m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to Santa Ana, California?

Best airlines flying from Columbia, Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Columbia, Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $383Free CancellationRating
7.4
9,930 reviews
Search United Airlines flights
American AirlinesPriceFrom $441Free CancellationRating
7.1
11,765 reviews
Search American Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbia to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbia to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Santa Ana?

Once all potential Columbia to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbia to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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