Cheap flights from Colorado to Panama City from $170

The cheapest month to fly to Panama City, Florida from Colorado is in November. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Panama City, Florida, with average flight prices from Colorado averaging around $370.

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $447. On the other hand, Thursday is the most expensive day to depart from Colorado because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $553.

Fly from Denver Intl to Panama City NW Florida Beaches for the best Colorado - Panama City NW Florida Beaches flight prices

You are more likely to see cheaper flights to Panama City, Florida from Colorado when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $407 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Colorado for as low as $363 on momondo.

There is only 1 cabin class available to choose from on Colorado to Panama City NW Florida Beaches flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 51% on your flight if you consider stops on a Colorado to Panama City, Florida flight.

Delta, United Airlines, and American Airlines are the most popular carriers operating from Colorado to Panama City NW Florida Beaches

Southwest, Frontier and American Airlines are the top three most popular airlines that fly to Panama City, Florida from Colorado according to our data. Southwest is the first choice among our users, with 29% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 6 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

The number of flights available between Colorado and Panama City, Florida is 5 per week as of March 2026. The most frequent departure day is Mon, with 20% of weekly flights leaving on this day.

Flight times vary depending on what airport in Colorado you fly out of and what airport in Panama City, Florida you fly into. For example, flying from Denver to Pensacola takes 2h 45m on average. On the other hand, flying from Colorado Springs to Pensacola takes 5h 25m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.