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Cheap flights from Chicago to Greenville from $90

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Greenville departing on 2/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:16 pm - 5:59 pm
ORD
-
GSP
20h 43m
1 stop
Multiple Airlines Logo
2:58 pm - 7:44 pm
GSP
-
ORD
29h 46m
1 stop
$194Multiple Airlines
jue., feb. 26 - jue., mar. 5
Multiple Airlines Logo
5:15 am - 3:51 pm
ORD
-
GSP
9h 36m
1 stop
Multiple Airlines Logo
4:41 pm - 7:11 pm
GSP
-
ORD
27h 30m
1 stop
$199Multiple Airlines
jue., mar. 5 - dom., mar. 8
United Airlines Logo
7:05 am - 10:01 am
ORD
-
GSP
1h 56mnonstop
United Airlines Logo
6:30 am - 7:53 am
GSP
-
ORD
2h 23mnonstop
$209United Airlines
mié., feb. 25 - mié., mar. 4
United Airlines Logo
7:05 am - 10:01 am
ORD
-
GSP
1h 56mnonstop
United Airlines Logo
10:00 am - 2:38 pm
GSP
-
ORD
5h 38m
1 stop
$219United Airlines
mié., feb. 18 - sáb., feb. 21
American Airlines Logo
8:55 pm - 11:58 pm
ORD
-
GSP
2h 03mnonstop
American Airlines Logo
8:19 pm - 9:39 pm
GSP
-
ORD
2h 20mnonstop
$224American Airlines
vie., may. 1 - lun., may. 4
Delta Logo
6:00 am - 12:21 pm
MDW
-
GSP
5h 21m
1 stop
Delta Logo
6:51 am - 9:56 am
GSP
-
MDW
4h 05m
1 stop
$229Delta
mié., abr. 15 - sáb., abr. 18
Delta Logo
5:37 pm - 10:24 pm
ORD
-
GSP
3h 47m
1 stop
Delta Logo
5:40 am - 10:14 am
GSP
-
ORD
5h 34m
1 stop
$229Delta
mié., feb. 25 - mar., mar. 3
American Airlines Logo
8:26 am - 3:36 pm
ORD
-
GSP
6h 10m
1 stop
American Airlines Logo
11:29 am - 12:41 pm
GSP
-
ORD
2h 12mnonstop
$234American Airlines
mié., feb. 25 - mar., mar. 3
Southwest Logo
10:05 am - 7:50 pm
MDW
-
GSP
8h 45m
2 stops
Southwest Logo
10:05 am - 2:55 pm
GSP
-
MDW
5h 50m
1 stop
$254Southwest
mié., feb. 25 - mié., mar. 4
Southwest Logo
1:25 pm - 8:20 pm
MDW
-
GSP
5h 55m
1 stop
Southwest Logo
10:05 am - 2:55 pm
GSP
-
MDW
5h 50m
1 stop
$260Southwest
lun., mar. 2 - mar., mar. 3

Delta flights from Chicago to Greenville

Our best Delta deals on Chicago to Greenville flight tickets
Delta
Apr 15
MDW6:00 amChicago Midway
5h 21m
1 stop
GSP12:21 pmGreenville
Apr 18
GSP6:51 amGreenville
4h 05m
1 stop
MDW9:56 amChicago Midway
$229
Delta
Feb 10
MDW6:14 pmChicago Midway
4h 36m
1 stop
GSP11:50 pmGreenville
Feb 14
GSP9:50 amGreenville
6h 31m
1 stop
MDW3:21 pmChicago Midway
$269
Delta
May 15
MDW6:00 amChicago Midway
6h 10m
1 stop
GSP1:10 pmGreenville
May 17
GSP6:45 amGreenville
4h 06m
1 stop
MDW9:51 amChicago Midway
$275

American Airlines flights from Chicago to Greenville

Our best American Airlines deals on Chicago to Greenville flight tickets
American Airlines
May 1
ORD8:55 pmChicago O'Hare Intl
2h 03m
GSP11:58 pmGreenville
May 4
GSP8:19 pmGreenville
2h 20m
ORD9:39 pmChicago O'Hare Intl
$224
American Airlines
Feb 25
ORD8:26 amChicago O'Hare Intl
6h 10m
1 stop
GSP3:36 pmGreenville
Mar 3
GSP11:29 amGreenville
2h 12m
ORD12:41 pmChicago O'Hare Intl
$234
American Airlines
Mar 2
ORD4:53 pmChicago O'Hare Intl
1h 53m
GSP7:46 pmGreenville
Mar 4
GSP11:29 amGreenville
2h 12m
ORD12:41 pmChicago O'Hare Intl
$240

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Chicago to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

jue. 2/26

8:16 pm-5:59 pm

1 stop20h 43m

Greenville

jue. 3/5

2:58 pm-7:44 pm

1 stop29h 46m

$194

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

jue. 3/5

5:15 am-3:51 pm

1 stop9h 36m

Greenville

dom. 3/8

4:41 pm-7:11 pm

1 stop27h 30m

$199

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

mié. 2/25

7:05 am-10:01 am

Nonstop1h 56m

Greenville

mié. 3/4

6:30 am-7:53 am

Nonstop2h 23m

$209

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

mié. 2/18

7:05 am-10:01 am

Nonstop1h 56m

Greenville

sáb. 2/21

10:00 am-2:38 pm

1 stop5h 38m

$219

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

vie. 5/1

8:55 pm-11:58 pm

Nonstop2h 03m

Greenville

lun. 5/4

8:19 pm-9:39 pm

Nonstop2h 20m

$224

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

mié. 4/15

6:00 am-12:21 pm

1 stop5h 21m

Greenville

sáb. 4/18

6:51 am-9:56 am

1 stop4h 05m

$229

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

mié. 2/25

5:37 pm-10:24 pm

1 stop3h 47m

Greenville

mar. 3/3

5:40 am-10:14 am

1 stop5h 34m

$229

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

mié. 2/25

8:26 am-3:36 pm

1 stop6h 10m

Greenville

mar. 3/3

11:29 am-12:41 pm

Nonstop2h 12m

$234

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

mié. 2/25

10:05 am-7:50 pm

2 stops8h 45m

Greenville

mié. 3/4

10:05 am-2:55 pm

1 stop5h 50m

$254

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

lun. 3/2

1:25 pm-8:20 pm

1 stop5h 55m

Greenville

mar. 3/3

10:05 am-2:55 pm

1 stop5h 50m

$260

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Chicago to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Greenville?

What is the cheapest month to fly to Greenville?

The month of April is another great option to travel to Greenville, with average flight prices from Chicago averaging around $262.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Chicago. The lowest ticket price found for a Saturday departure recently was $269. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $393. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Chicago to Greenville during this time can be as low as $286. Flights to Greenville are more costly in the evening, with an average ticket price of $313. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago to Greenville flight route?

Fly from Chicago O'Hare Intl to Greenville for the best Chicago - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $301 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Chicago for as low as $224 on momondo.

What cabin class options are available on Chicago to Greenville flights?

There are 4 cabin classes available to choose from on Chicago to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Greenville flights?

No. A direct flight is the cheapest option for a flight between Chicago to Greenville.

How have Chicago to Greenville flight prices changed over time?

As of January 2026, prices for Chicago to Greenville flights are approximately 17% more expensive when compared to flights at the same time last year.

When to book flights from Chicago to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Greenville (CHI to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Greenville

Best Price Found

$144

Fastest flight time

1h 56m

Direct flights

Every day

Airports in Greenville

1 airport
The best one-way flight to Greenville from Chicago in the past 72 hours is $144. The best round-trip flight deal from Chicago to Greenville found on momondo in the last 72 hours is $209.
The fastest flight from Chicago to Greenville takes 1h 56m
Direct flights go from Chicago to Greenville every day.
There is 1 airport in Greenville. From Chicago there are direct flights to Greenville (GSP).
Search flight deals

  • How far is Chicago to Greenville by plane?

    The straight-line distance from Chicago to Greenville is 561.3 mi. 1h 56m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Greenville Airport?

    Prices for flights from Chicago to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from Chicago to Greenville Airport?

  • How old do you have to be to fly from Chicago to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago to Greenville?

  • What is the most popular airline from Chicago to Greenville?

Best airlines flying from Chicago to Greenville

Compare and see reviews for airlines that fly from Chicago to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $118Free CancellationRating
7.9
8,128 reviews
Search Delta flights
American AirlinesPriceFrom $202Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights
United AirlinesPriceFrom $209Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights

  • United Airlines Flights From Chicago to Greenville

    Across 16 United Airlines flights from Chicago to Greenville this week, the average price was $327, with the best United Airlines deals starting from $209 round-trip. 9,215 users have rated United Airlines on momondo, with an average score of 7.4/10.

  • American Airlines Flights From Chicago to Greenville

    $202 is the best American Airlines flight deal from Chicago to Greenville found on momondo over the last 72 hours. The average American Airlines ticket price found was closer to $283, however, with flight time and availability significantly affecting the price. American Airlines (7.2/10 from 11,205 user reviews) flies into Greenville from Chicago 12 times in an average week so prices can vary.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Greenville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Greenville. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Greenville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Greenville from Chicago with this policy.

How can momondo help me find flights from Chicago to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from Chicago.

I’m not ready to book a flight from Chicago to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from Chicago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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