Cheap flights from Central America to San Francisco from $248

If you aren’t able to travel to San Francisco during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $427.

The cheapest day to depart from Central America to San Francisco is on a Saturday when prices can be found for as low as $470. The most expensive day to fly to San Francisco is Wednesday, with ticket prices averaging around $580.

Our data shows that the cheapest Central America to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $534. Flights in the afternoon are often more expensive with an average ticket price of $538.

Fly from San José Juan Santamaria Intl to San Francisco for the best Central America - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Central America when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $514 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Central America for as low as $452 on momondo.

There are 3 cabin classes available to choose from on Central America to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, United Airlines, and Southwest are the most popular carriers operating from Central America to San Francisco

Avianca, United Airlines and Copa Airlines are the top three most popular airlines that fly to San Francisco from Central America according to our data. Avianca is the first choice among our users, with 67% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 8 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

7 flights are operational daily from Central America to San Francisco as of June 2026. The most popular departure time for this route is 5:00PM, with 54% of flights per day taking off in the afternoon.

As of June 2026, there are 52 flights per week flying from Central America to San Francisco. The most common day of the week flights depart is Tue, with 19% of flights taking off on this day.