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Cheap flights from the Cayman Islands to San Diego from $293

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the Cayman Islands to San Diego departing on 6/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from the Cayman Islands to San Diego

Recent round-trip flight deals from the Cayman Islands to San Diego

Enter your travel dates to find the best prices.
Multiple Airlines Logo
GCM
-
SAN
2395 mimulti-stop
Multiple Airlines Logo
SAN
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GCM
2395 mimulti-stop
Multiple Airlines
Multiple Airlines Logo
CYB
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SAN
2465 mimulti-stop
Multiple Airlines Logo
SAN
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CYB
2465 mimulti-stop
Multiple Airlines

American Airlines flights from Cayman Islands to San Diego

Our best American Airlines deals on Cayman Islands to San Diego flight tickets
American Airlines
May 21
GCM12:33 pmGeorge Town Owen Roberts Intl
11h 15m
1 stop
SAN9:48 pmSan Diego
May 24
SAN9:25 pmSan Diego
12h 05m
1 stop
GCM11:30 amGeorge Town Owen Roberts Intl
$695
American Airlines
May 21
GCM5:12 pmGeorge Town Owen Roberts Intl
18h 55m
2 stops
SAN10:07 amSan Diego
May 24
SAN9:25 pmSan Diego
12h 05m
1 stop
GCM11:30 amGeorge Town Owen Roberts Intl
$700
American Airlines
May 21
GCM2:42 pmGeorge Town Owen Roberts Intl
11h 17m
1 stop
SAN11:59 pmSan Diego
May 24
SAN10:28 pmSan Diego
11h 02m
1 stop
GCM11:30 amGeorge Town Owen Roberts Intl
$733

momondo Fare Finder

 
Customize your flight search to find flights from Cayman Islands to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from the Cayman Islands to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest one-way

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 6/6

4:45 pm-7:50 pm

1 stop29h 05m

$293

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 6/6

1:50 pm-9:59 am

2 stops22h 09m

$298

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Mon 6/1

4:45 pm-11:50 pm

3 stops57h 05m

$354
Quickest one-way

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 5/29

1:35 pm-9:24 pm

1 stop9h 49m

$355

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 5/28

1:19 pm-11:27 pm

1 stop12h 08m

$359

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 5/28

1:35 pm-12:30 am

2 stops12h 55m

$364

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Wed 5/27

1:19 pm-11:27 pm

1 stop12h 08m

$400

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Wed 5/27

1:35 pm-10:25 pm

2 stops10h 50m

$405

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 5/29

1:35 pm-6:39 pm

3 stops31h 04m

$432

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sun 5/31

12:40 pm-8:47 am

3 stops46h 07m

$433

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to San Diego from

How to get the cheapest flight ticket from Cayman Islands to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Cayman Islands to San Diego flights?

You could potentially save up to 11% on your flight if you consider stops on a Cayman Islands to San Diego flight.

Cheap Cayman Islands to San Diego flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cayman Islands to San Diego

Fastest flight time

9h 49m

Direct flights

None
The fastest flight from Cayman Islands to San Diego takes 9h 49m
There are no direct flights from Cayman Islands to San Diego. There are no popular flight routes from Cayman Islands to San Diego.
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Frequently asked questions about flying from the Cayman Islands to San Diego

  • When did momondo last update prices for flights from Cayman Islands to San Diego Airport?

    Prices for flights from Cayman Islands to San Diego Airport refresh daily.

  • How old do you have to be to fly from Cayman Islands to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cayman Islands to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Imperial Beach
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Cayman Islands to San Diego?

Finding the right flight to San Diego from Cayman Islands is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Cayman Islands to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Cayman Islands to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Cayman Islands to San Diego?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cayman Islands to San Diego.

I’m not ready to book a flight from Cayman Islands to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cayman Islands to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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