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Cheap flights from California to Florence from $224

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from California to Florence departing on 4/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from California to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 6:05 pm
SFO
-
FLO
8h 05m1 stop
American Airlines Logo
6:15 am - 4:01 pm
FLO
-
SFO
12h 46m2 stops
$525American Airlines
Fri, Jan 2 - Tue, Jan 6
American Airlines Logo
10:53 am - 10:43 pm
SNA
-
FLO
8h 50m2 stops
American Airlines Logo
6:15 am - 6:01 pm
FLO
-
SNA
14h 46m2 stops
$549American Airlines
Fri, Jan 16 - Sat, Jan 17
American Airlines Logo
7:00 am - 6:05 pm
SFO
-
FLO
8h 05m1 stop
American Airlines Logo
5:36 pm - 10:28 pm
FLO
-
SFO
7h 52m1 stop
$578American Airlines
Fri, Jan 2 - Tue, Jan 6
American Airlines Logo
9:55 am - 10:43 pm
SJC
-
FLO
9h 48m2 stops
American Airlines Logo
6:15 am - 6:34 pm
FLO
-
SJC
15h 19m2 stops
$632American Airlines
Tue, Feb 3 - Tue, Feb 10
American Airlines Logo
11:55 am - 12:15 am
SAN
-
FLO
9h 20m1 stop
American Airlines Logo
6:15 am - 11:33 am
FLO
-
SAN
8h 18m1 stop
$645American Airlines
Sat, Jan 3 - Wed, Jan 7
American Airlines Logo
11:55 am - 12:15 am
SAN
-
FLO
9h 20m1 stop
American Airlines Logo
6:15 am - 3:57 pm
FLO
-
SAN
12h 42m2 stops
$650American Airlines
Sat, Jan 3 - Wed, Jan 7
American Airlines Logo
11:59 pm - 12:42 pm
SFO
-
FLO
9h 43m2 stops
American Airlines Logo
6:15 am - 4:01 pm
FLO
-
SFO
12h 46m2 stops
$661American Airlines
Fri, Jan 2 - Tue, Jan 6
American Airlines Logo
6:00 am - 6:05 pm
SJC
-
FLO
9h 05m2 stops
American Airlines Logo
6:15 am - 1:42 pm
FLO
-
SJC
10h 27m2 stops
$817American Airlines
Sat, Jan 3 - Wed, Jan 7
American Airlines Logo
6:15 am - 6:05 pm
SAN
-
FLO
8h 50m2 stops
American Airlines Logo
6:15 am - 3:57 pm
FLO
-
SAN
12h 42m2 stops
$836American Airlines
Sat, Jan 3 - Wed, Jan 7
American Airlines Logo
12:49 am - 12:42 pm
LAX
-
FLO
8h 53m1 stop
American Airlines Logo
6:15 am - 10:52 am
FLO
-
LAX
7h 37m1 stop
$929American Airlines
Sat, Jan 3 - Thu, Jan 8

American Airlines flights from California to Florence, South Carolina

Our best American Airlines deals on California to Florence, South Carolina flight tickets
American Airlines
Dec 26
SFO7:00 amSan Francisco
8h 05m
1 stop
FLO6:05 pmFlorence
Dec 30
FLO5:15 amFlorence
10h 08m
1 stop
SFO12:23 pmSan Francisco
$541
Find similar
American Airlines
Dec 26
SFO9:15 amSan Francisco
12h 00m
2 stops
FLO12:15 amFlorence
Dec 30
FLO5:15 amFlorence
10h 08m
1 stop
SFO12:23 pmSan Francisco
$546
Find similar
American Airlines
Jan 16
SNA10:53 amSanta Ana J. Wayne/Orange Cnty
8h 50m
2 stops
FLO10:43 pmFlorence
Jan 17
FLO6:15 amFlorence
14h 46m
2 stops
SNA6:01 pmSanta Ana J. Wayne/Orange Cnty
$549
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from California to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from California to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Fri 1/2

7:00 am-6:05 pm

1 stop8h 05m

Florence

Tue 1/6

6:15 am-4:01 pm

2 stops12h 46m

$525

Santa AnaFlorence

SNA - FLO

SNAFLO

Santa Ana J. Wayne/Orange Cnty

Fri 1/16

10:53 am-10:43 pm

2 stops8h 50m

Florence

Sat 1/17

6:15 am-6:01 pm

2 stops14h 46m

$549

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Fri 1/2

7:00 am-6:05 pm

1 stop8h 05m

Florence

Tue 1/6

5:36 pm-10:28 pm

1 stop7h 52m

$578

San JoseFlorence

SJC - FLO

SJCFLO

San Jose

Tue 2/3

9:55 am-10:43 pm

2 stops9h 48m

Florence

Tue 2/10

6:15 am-6:34 pm

2 stops15h 19m

$632

San DiegoFlorence

SAN - FLO

SANFLO

San Diego

Sat 1/3

11:55 am-12:15 am

1 stop9h 20m

Florence

Wed 1/7

6:15 am-11:33 am

1 stop8h 18m

$645

San DiegoFlorence

SAN - FLO

SANFLO

San Diego

Sat 1/3

11:55 am-12:15 am

1 stop9h 20m

Florence

Wed 1/7

6:15 am-3:57 pm

2 stops12h 42m

$650

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Fri 1/2

11:59 pm-12:42 pm

2 stops9h 43m

Florence

Tue 1/6

6:15 am-4:01 pm

2 stops12h 46m

$661

San JoseFlorence

SJC - FLO

SJCFLO

San Jose

Sat 1/3

6:00 am-6:05 pm

2 stops9h 05m

Florence

Wed 1/7

6:15 am-1:42 pm

2 stops10h 27m

$817

San DiegoFlorence

SAN - FLO

SANFLO

San Diego

Sat 1/3

6:15 am-6:05 pm

2 stops8h 50m

Florence

Wed 1/7

6:15 am-3:57 pm

2 stops12h 42m

$836

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Sat 1/3

12:49 am-12:42 pm

1 stop8h 53m

Florence

Thu 1/8

6:15 am-10:52 am

1 stop7h 37m

$929

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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How to get the cheapest flight ticket from California to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from California is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $472. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Friday is the most expensive day to depart from California because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $759.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is at noon. momondo users have found flights departing from California to Florence, South Carolina at noon for as low as $695. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $714 per ticket.

Can stopping save me money on California to Florence, South Carolina flights?

You could potentially save up to 54% on your flight if you consider stops on a California to Florence, South Carolina flight.

Cheap California to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from California to Florence, South Carolina

Fastest flight time

7h 49m

Direct flights

None
The fastest flight from California to Florence, South Carolina takes 7h 49m
There are no direct flights from California to Florence, South Carolina. There are no popular flight routes from California to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from California to Florence Airport?

    Prices for flights from California to Florence Airport are updated daily.

  • How many operators does momondo search for flights from California to Florence Airport?

  • How old do you have to be to fly from California to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from California to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from California to Florence, South Carolina

Compare and see reviews for airlines that fly from California to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $400Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from California to Florence?

It is quick and easy to find California to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from California to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from California with this policy.

How can momondo help me find flights from California to Florence?

momondo helps you find the best flight between California and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from California to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from California. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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