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Cheap flights from California to Florence from $224

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from California to Florence departing on 4/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from California to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:31 pm - 11:08 pm
SFO
-
FLO
7h 37m
1 stop
American Airlines Logo
6:20 pm - 11:10 pm
FLO
-
SFO
7h 50m
1 stop
$437American Airlines
Wed, Mar 4 - Wed, Mar 11
American Airlines Logo
12:30 am - 5:21 pm
SFO
-
FLO
13h 51m
2 stops
American Airlines Logo
6:20 pm - 11:10 pm
FLO
-
SFO
7h 50m
1 stop
$442American Airlines
Tue, Mar 3 - Wed, Mar 11
American Airlines Logo
12:30 am - 5:21 pm
SFO
-
FLO
13h 51m
2 stops
American Airlines Logo
5:16 am - 2:34 pm
FLO
-
SFO
12h 18m
2 stops
$447American Airlines
Tue, Mar 3 - Wed, Mar 11
American Airlines Logo
12:19 pm - 11:57 pm
LAX
-
FLO
8h 38m
1 stop
American Airlines Logo
4:16 pm - 10:55 pm
FLO
-
LAX
9h 39m
1 stop
$489American Airlines
Fri, Apr 3 - Sat, Apr 11
American Airlines Logo
12:19 pm - 11:57 pm
LAX
-
FLO
8h 38m
1 stop
American Airlines Logo
4:16 pm - 10:05 pm
FLO
-
LAX
8h 49m
2 stops
$494American Airlines
Fri, Apr 3 - Sat, Apr 11
American Airlines Logo
6:15 am - 5:50 pm
SAN
-
FLO
8h 35m
1 stop
American Airlines Logo
6:15 am - 1:28 pm
FLO
-
SAN
10h 13m
1 stop
$512American Airlines
Sun, Mar 15 - Tue, Mar 31
American Airlines Logo
1:37 pm - 11:57 pm
SAN
-
FLO
7h 20m
1 stop
American Airlines Logo
6:15 am - 6:04 pm
FLO
-
SAN
14h 49m
2 stops
$517American Airlines
Sun, Mar 15 - Tue, Mar 31
American Airlines Logo
12:20 pm - 11:08 pm
LAX
-
FLO
7h 48m
1 stop
American Airlines Logo
6:20 pm - 12:57 am
FLO
-
LAX
9h 37m
1 stop
$519American Airlines
Wed, Feb 25 - Sun, Mar 8
American Airlines Logo
10:19 am - 11:08 pm
LAX
-
FLO
9h 49m
2 stops
American Airlines Logo
6:20 pm - 11:18 pm
FLO
-
LAX
7h 58m
1 stop
$524American Airlines
Wed, Feb 25 - Sun, Mar 8
American Airlines Logo
6:09 am - 5:50 pm
LAX
-
FLO
8h 41m
1 stop
American Airlines Logo
6:20 pm - 11:18 pm
FLO
-
LAX
7h 58m
1 stop
$527American Airlines
Thu, Apr 2 - Mon, Apr 6

American Airlines flights from California to Florence, South Carolina

Our best American Airlines deals on California to Florence, South Carolina flight tickets
American Airlines
Mar 4
SFO12:31 pmSan Francisco
7h 37m
1 stop
FLO11:08 pmFlorence
Mar 11
FLO6:20 pmFlorence
7h 50m
1 stop
SFO11:10 pmSan Francisco
$437
American Airlines
Mar 3
SFO12:30 amSan Francisco
13h 51m
2 stops
FLO5:21 pmFlorence
Mar 11
FLO6:20 pmFlorence
7h 50m
1 stop
SFO11:10 pmSan Francisco
$442
American Airlines
Mar 3
SFO12:30 amSan Francisco
13h 51m
2 stops
FLO5:21 pmFlorence
Mar 11
FLO5:16 amFlorence
12h 18m
2 stops
SFO2:34 pmSan Francisco
$447

momondo Fare Finder

 
Customize your flight search to find flights from California to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from California to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Wed 3/4

12:31 pm-11:08 pm

1 stop7h 37m

Florence

Wed 3/11

6:20 pm-11:10 pm

1 stop7h 50m

$437

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Tue 3/3

12:30 am-5:21 pm

2 stops13h 51m

Florence

Wed 3/11

6:20 pm-11:10 pm

1 stop7h 50m

$442

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Tue 3/3

12:30 am-5:21 pm

2 stops13h 51m

Florence

Wed 3/11

5:16 am-2:34 pm

2 stops12h 18m

$447

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Fri 4/3

12:19 pm-11:57 pm

1 stop8h 38m

Florence

Sat 4/11

4:16 pm-10:55 pm

1 stop9h 39m

$489

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Fri 4/3

12:19 pm-11:57 pm

1 stop8h 38m

Florence

Sat 4/11

4:16 pm-10:05 pm

2 stops8h 49m

$494

San DiegoFlorence

SAN - FLO

SANFLO

San Diego

Sun 3/15

6:15 am-5:50 pm

1 stop8h 35m

Florence

Tue 3/31

6:15 am-1:28 pm

1 stop10h 13m

$512

San DiegoFlorence

SAN - FLO

SANFLO

San Diego

Sun 3/15

1:37 pm-11:57 pm

1 stop7h 20m

Florence

Tue 3/31

6:15 am-6:04 pm

2 stops14h 49m

$517

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Wed 2/25

12:20 pm-11:08 pm

1 stop7h 48m

Florence

Sun 3/8

6:20 pm-12:57 am

1 stop9h 37m

$519

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Wed 2/25

10:19 am-11:08 pm

2 stops9h 49m

Florence

Sun 3/8

6:20 pm-11:18 pm

1 stop7h 58m

$524

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Thu 4/2

6:09 am-5:50 pm

1 stop8h 41m

Florence

Mon 4/6

6:20 pm-11:18 pm

1 stop7h 58m

$527

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from California to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on California to Florence, South Carolina flights?

You could potentially save up to 54% on your flight if you consider stops on a California to Florence, South Carolina flight.

Cheap California to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from California to Florence, South Carolina

Fastest flight time

6h 30m

Direct flights

None
The fastest flight from California to Florence, South Carolina takes 6h 30m
There are no direct flights from California to Florence, South Carolina. There are no popular flight routes from California to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from California to Florence Airport?

    Prices for flights from California to Florence Airport are updated daily.

  • How many operators does momondo search for flights from California to Florence Airport?

  • How old do you have to be to fly from California to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from California to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from California to Florence, South Carolina

Compare and see reviews for airlines that fly from California to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $412Free CancellationRating
7.2
11,237 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from California to Florence?

It is quick and easy to find California to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from California to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from California with this policy.

How can momondo help me find flights from California to Florence?

momondo helps you find the best flight between California and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from California to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from California. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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