Cheap flights from Washington, D.C. to Panama City from $120

The cheapest month to fly to Panama City, Florida from Washington, D.C. is in January. Flight prices, which tend to average around $415, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Washington, D.C. averaging around $435.

Our data shows that Saturday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $411. On the other hand, Thursday is the most expensive day to depart from Washington, D.C. because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $588.

Fly from Washington, D.C. Reagan-National to Panama City NW Florida Beaches for the best Washington, D.C. - Panama City NW Florida Beaches flight prices

There are 3 cabin classes available to choose from on Washington, D.C. to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 37% on your flight if you consider stops on a Washington, D.C. to Panama City, Florida flight.

As of September 2026, prices for Washington, D.C. to Panama City, Florida flights are approximately 21% cheaper when compared to flights at the same time last year.

Southwest, Delta, and United Airlines are the most popular carriers operating from Washington, D.C. to Panama City NW Florida Beaches

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Panama City, Florida from Washington, D.C. according to our data. American Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 6 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

Nashville (BNA) was the most common stop: 46% of momondo users choosing 1-stop flights on this route connected there.

Flights via Atlanta (ATL) offer the lowest average round-trip price of $292.

Flights connecting via Nashville (BNA) have the shortest average one-way travel time: 4h 26m.

Charlotte (CLT) has the shortest average layover time for this route: 1h 00m.

The number of flights available between Washington, D.C. and Panama City, Florida is 6 per week as of September 2026. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.

Flight times vary depending on what airport in Washington, D.C. you fly out of and what airport in Panama City, Florida you fly into. For example, flying from Washington, D.C. to Pensacola takes 3h 44m on average. On the other hand, flying from Baltimore to Pensacola takes 4h 15m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.