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Cheap flights from Sioux Falls to St. Louis from $135

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to St. Louis departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Sioux Falls to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
4:25 pm - 7:23 pm
FSD
-
STL
26h 58m
1 stop
Frontier Logo
8:08 pm - 3:40 pm
STL
-
FSD
19h 32m
1 stop
$205Frontier
Fri, May 22 - Thu, May 28
American Airlines Logo
7:45 pm - 11:46 pm
FSD
-
STL
4h 01m
1 stop
American Airlines Logo
7:12 am - 12:56 pm
STL
-
FSD
5h 44m
1 stop
$281American Airlines
Wed, Apr 29 - Wed, May 6
American Airlines Logo
7:30 am - 2:45 pm
FSD
-
STL
7h 15m
1 stop
American Airlines Logo
10:14 am - 5:22 pm
STL
-
FSD
7h 08m
1 stop
$290American Airlines
Thu, Sep 3 - Sat, Sep 5
American Airlines Logo
6:47 am - 2:03 pm
FSD
-
STL
7h 16m
1 stop
American Airlines Logo
5:20 am - 12:56 pm
STL
-
FSD
7h 36m
1 stop
$295American Airlines
Sat, Apr 18 - Sat, May 2
American Airlines Logo
7:39 pm - 11:56 pm
FSD
-
STL
4h 17m
1 stop
American Airlines Logo
7:05 am - 11:59 am
STL
-
FSD
4h 54m
1 stop
$309American Airlines
Thu, May 14 - Sun, May 17
Delta Logo
5:15 am - 8:40 am
FSD
-
STL
3h 25m
1 stop
Delta Logo
5:30 pm - 10:46 pm
STL
-
FSD
5h 16m
1 stop
$314Delta
Fri, Sep 25 - Sat, Sep 26
United Airlines Logo
1:43 pm - 8:54 pm
FSD
-
STL
7h 11m
1 stop
United Airlines Logo
6:55 pm - 11:44 pm
STL
-
FSD
4h 49m
1 stop
$319United Airlines
Wed, Apr 15 - Sun, Apr 19
American Airlines Logo
5:34 pm - 11:56 pm
FSD
-
STL
6h 22m
1 stop
American Airlines Logo
6:00 am - 11:39 am
STL
-
FSD
5h 39m
1 stop
$331American Airlines
Sat, Jul 11 - Wed, Jul 15
American Airlines Logo
5:34 pm - 11:56 pm
FSD
-
STL
6h 22m
1 stop
American Airlines Logo
9:08 am - 4:19 pm
STL
-
FSD
7h 11m
1 stop
$335American Airlines
Sat, Jul 11 - Wed, Jul 15
United Airlines Logo
6:00 am - 1:13 pm
FSD
-
STL
7h 13m
1 stop
United Airlines Logo
5:28 pm - 9:52 pm
STL
-
FSD
4h 24m
1 stop
$341United Airlines
Tue, May 5 - Sat, May 9

United Airlines flights from Sioux Falls to St. Louis

Our best United Airlines deals on Sioux Falls to St. Louis flight tickets
United Airlines
Apr 15
FSD1:43 pmSioux Falls Joe Foss Field
7h 11m
1 stop
STL8:54 pmLambert-St Louis
Apr 19
STL6:55 pmLambert-St Louis
4h 49m
1 stop
FSD11:44 pmSioux Falls Joe Foss Field
$319
United Airlines
May 5
FSD6:00 amSioux Falls Joe Foss Field
7h 13m
1 stop
STL1:13 pmLambert-St Louis
May 9
STL5:28 pmLambert-St Louis
4h 24m
1 stop
FSD9:52 pmSioux Falls Joe Foss Field
$341
United Airlines
May 28
FSD5:05 pmSioux Falls Joe Foss Field
6h 52m
1 stop
STL11:57 pmLambert-St Louis
Jul 1
STL5:33 pmLambert-St Louis
4h 34m
1 stop
FSD10:07 pmSioux Falls Joe Foss Field
$348

American Airlines flights from Sioux Falls to St. Louis

Our best American Airlines deals on Sioux Falls to St. Louis flight tickets
American Airlines
Apr 29
FSD7:45 pmSioux Falls Joe Foss Field
4h 01m
1 stop
STL11:46 pmLambert-St Louis
May 6
STL7:12 amLambert-St Louis
5h 44m
1 stop
FSD12:56 pmSioux Falls Joe Foss Field
$281
American Airlines
Sep 3
FSD7:30 amSioux Falls Joe Foss Field
7h 15m
1 stop
STL2:45 pmLambert-St Louis
Sep 5
STL10:14 amLambert-St Louis
7h 08m
1 stop
FSD5:22 pmSioux Falls Joe Foss Field
$290
American Airlines
Apr 18
FSD6:47 amSioux Falls Joe Foss Field
7h 16m
1 stop
STL2:03 pmLambert-St Louis
May 2
STL5:20 amLambert-St Louis
7h 36m
1 stop
FSD12:56 pmSioux Falls Joe Foss Field
$295

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 5/22

4:25 pm-7:23 pm

1 stop26h 58m

Lambert-St Louis

Thu 5/28

8:08 pm-3:40 pm

1 stop19h 32m

$205

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 4/29

7:45 pm-11:46 pm

1 stop4h 01m

Lambert-St Louis

Wed 5/6

7:12 am-12:56 pm

1 stop5h 44m

$281

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 9/3

7:30 am-2:45 pm

1 stop7h 15m

Lambert-St Louis

Sat 9/5

10:14 am-5:22 pm

1 stop7h 08m

$290

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 4/18

6:47 am-2:03 pm

1 stop7h 16m

Lambert-St Louis

Sat 5/2

5:20 am-12:56 pm

1 stop7h 36m

$295

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 5/14

7:39 pm-11:56 pm

1 stop4h 17m

Lambert-St Louis

Sun 5/17

7:05 am-11:59 am

1 stop4h 54m

$309
Quickest round-trip

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 9/25

5:15 am-8:40 am

1 stop3h 25m

Lambert-St Louis

Sat 9/26

5:30 pm-10:46 pm

1 stop5h 16m

$314

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 4/15

1:43 pm-8:54 pm

1 stop7h 11m

Lambert-St Louis

Sun 4/19

6:55 pm-11:44 pm

1 stop4h 49m

$319

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 7/11

5:34 pm-11:56 pm

1 stop6h 22m

Lambert-St Louis

Wed 7/15

6:00 am-11:39 am

1 stop5h 39m

$331

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 7/11

5:34 pm-11:56 pm

1 stop6h 22m

Lambert-St Louis

Wed 7/15

9:08 am-4:19 pm

1 stop7h 11m

$335

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Tue 5/5

6:00 am-1:13 pm

1 stop7h 13m

Lambert-St Louis

Sat 5/9

5:28 pm-9:52 pm

1 stop4h 24m

$341

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Sioux Falls to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Sioux Falls and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Sioux Falls to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $278. The month of August is another great option to travel to St. Louis, with average flight prices from Sioux Falls averaging around $288.

When to book flights from Sioux Falls to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to St. Louis (FSD to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to St. Louis

Fastest flight time

4h 07m

Direct flights

None
The fastest flight from Sioux Falls to St. Louis takes 4h 07m
There are no direct flights from Sioux Falls to St. Louis. There are no popular flight routes from Sioux Falls to St. Louis.
Search flight deals

Frequently asked questions about flying from Sioux Falls to St. Louis

  • How far is Sioux Falls Joe Foss Field to Lambert-St Louis by plane?

    The distance between Sioux Falls Joe Foss Field and Lambert-St Louis is about 480.2 mi. 4h 07m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Lambert-St Louis Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Lambert-St Louis Airport were last updated today.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The necessary travel and health documents for your Lambert-St Louis Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Sioux Falls to St. Louis?

Best airlines flying from Sioux Falls to St. Louis

Compare and see reviews for airlines that fly from Sioux Falls to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $228Free CancellationRating
7.9
8,383 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,555 reviews
Search American Airlines flights
United AirlinesPriceFrom $268Free CancellationRating
7.4
9,541 reviews
Search United Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
St. Peters
Collinsville
Alton
Wentzville
Fenton
Farmington
Clayton
Festus
Eureka
Edwardsville
Litchfield
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Sioux Falls to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from Sioux Falls to St. Louis with flexible booking policies on momondo?

Flights from Sioux Falls to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Sioux Falls to St. Louis?

momondo helps you find the best flight between Sioux Falls and St. Louis by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Sioux Falls to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Sioux Falls to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.

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