Cheap flights from Santa Cruz de la Sierra to San Francisco from $423

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to San Francisco departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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United Airlines Logo
11:40 am - 5:42 pmVVI-SFO
34h 02m2 stops
United Airlines Logo
6:53 pm - 10:50 pmSFO-VVI
23h 57m2 stops
$820United Airlines
Find Deal
Thu, Dec 18 - Wed, Jan 7
United Airlines Logo
11:48 am - 11:19 amVVI-SFO
26h 31m2 stops
United Airlines Logo
5:00 am - 3:40 amSFO-VVI
19h 40m2 stops
$855United Airlines
Find Deal
Mon, Apr 13 - Mon, Apr 27
Avianca Logo
3:40 am - 9:50 pmVVI-SFO
22h 10m2 stops
Avianca Logo
11:10 pm - 2:35 amSFO-VVI
23h 25m2 stops
$923Avianca
Find Deal
Tue, Jan 20 - Tue, Feb 10
Copa Airlines Logo
1:12 am - 11:40 pmVVI-SFO
25h 28m1 stop
Copa Airlines Logo
1:12 am - 3:31 amSFO-VVI
23h 19m1 stop
$934Copa Airlines
Find Deal
Tue, May 5 - Sat, May 9
Copa Airlines Logo
11:40 am - 11:17 pmVVI-SFO
15h 37m1 stop
Copa Airlines Logo
12:42 am - 10:50 pmSFO-VVI
18h 08m1 stop
$1,074Copa Airlines
Find Deal
Thu, Dec 18 - Tue, Jan 6
United Airlines Logo
11:40 am - 11:17 pmVVI-SFO
15h 37m1 stop
United Airlines Logo
12:43 am - 3:44 amSFO-VVI
23h 01m2 stops
$1,105United Airlines
Find Deal
Thu, Dec 18 - Tue, Jan 6
Multiple Airlines Logo
5:25 am - 12:35 pmVVI-SFO
34h 10m3 stops
Multiple Airlines Logo
12:05 am - 1:50 amSFO-VVI
22h 45m2 stops
$1,106Multiple Airlines
Find Deal
Wed, Apr 29 - Wed, May 13
Avianca Logo
3:40 am - 11:20 pmVVI-SFO
23h 40m2 stops
Avianca Logo
1:35 am - 2:35 amSFO-VVI
21h 00m2 stops
$1,167Avianca
Find Deal
Wed, Dec 17 - Tue, Jan 6
Avianca Logo
2:55 am - 12:35 pmVVI-SFO
36h 40m2 stops
Avianca Logo
12:05 am - 1:50 amSFO-VVI
22h 45m2 stops
$1,176Avianca
Find Deal
Thu, Apr 9 - Fri, Apr 24
Avianca Logo
3:40 am - 11:20 pmVVI-SFO
23h 40m2 stops
Avianca Logo
1:35 am - 2:35 amSFO-VVI
21h 00m2 stops
$1,179Avianca
Find Deal
Wed, Dec 17 - Tue, Jan 6

United Airlines flights from Santa Cruz de la Sierra to San Francisco

Our best United Airlines deals on Santa Cruz de la Sierra to San Francisco flight tickets
United Airlines
Dec 18
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
34h 02m
2 stops
SFO5:42 pmSan Francisco
Jan 7
SFO6:53 pmSan Francisco
23h 57m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
United Airlines
Dec 11
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
25h 56m
2 stops
SFO9:36 amSan Francisco
Jan 15
SFO9:20 pmSan Francisco
21h 30m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
United Airlines
Apr 13
VVI11:48 amSanta Cruz de la Sierra Viru Viru Intl
28h 23m
2 stops
SFO1:11 pmSan Francisco
Apr 29
SFO7:00 amSan Francisco
17h 40m
2 stops
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl

Copa Airlines flights from Santa Cruz de la Sierra to San Francisco

Our best Copa Airlines deals on Santa Cruz de la Sierra to San Francisco flight tickets
Copa Airlines
May 5
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
25h 28m
1 stop
SFO11:40 pmSan Francisco
May 10
SFO8:06 pmSan Francisco
23h 32m
1 stop
VVI10:38 pmSanta Cruz de la Sierra Viru Viru Intl
Copa Airlines
Dec 18
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
15h 37m
1 stop
SFO11:17 pmSan Francisco
Jan 6
SFO12:42 amSan Francisco
18h 08m
1 stop
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Copa Airlines
Feb 18
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
26h 05m
1 stop
SFO11:20 pmSan Francisco
Feb 21
SFO12:42 amSan Francisco
18h 08m
1 stop
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/18

11:40 am-5:42 pm

2 stops34h 02m

San Francisco

Wed 1/7

6:53 pm-10:50 pm

2 stops23h 57m

$820

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/13

11:48 am-11:19 am

2 stops26h 31m

San Francisco

Mon 4/27

5:00 am-3:40 am

2 stops19h 40m

$855

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 1/20

3:40 am-9:50 pm

2 stops22h 10m

San Francisco

Tue 2/10

11:10 pm-2:35 am

2 stops23h 25m

$923

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

1:12 am-11:40 pm

1 stop25h 28m

San Francisco

Sat 5/9

1:12 am-3:31 am

1 stop23h 19m

$934

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/18

11:40 am-11:17 pm

1 stop15h 37m

San Francisco

Tue 1/6

12:42 am-10:50 pm

1 stop18h 08m

$1,074

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/18

11:40 am-11:17 pm

1 stop15h 37m

San Francisco

Tue 1/6

12:43 am-3:44 am

2 stops23h 01m

$1,105

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/29

5:25 am-12:35 pm

3 stops34h 10m

San Francisco

Wed 5/13

12:05 am-1:50 am

2 stops22h 45m

$1,106

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/17

3:40 am-11:20 pm

2 stops23h 40m

San Francisco

Tue 1/6

1:35 am-2:35 am

2 stops21h 00m

$1,167

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/9

2:55 am-12:35 pm

2 stops36h 40m

San Francisco

Fri 4/24

12:05 am-1:50 am

2 stops22h 45m

$1,176

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/17

3:40 am-11:20 pm

2 stops23h 40m

San Francisco

Tue 1/6

1:35 am-2:35 am

2 stops21h 00m

$1,179

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Santa Cruz de la Sierra to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of September, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $543.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Santa Cruz de la Sierra to San Francisco is on a Tuesday when prices can be found for as low as $618. The most expensive day to fly to San Francisco is Saturday, with ticket prices averaging around $1,267.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Santa Cruz de la Sierra to San Francisco flights are usually those with departure times in the evening. Our users have found flights to San Francisco in the evening for as low as $734. Flights in the morning are often more expensive with an average ticket price of $831.

Can stopping save me money on Santa Cruz de la Sierra to San Francisco flights?

You could potentially save up to 46% on your flight if you consider stops on a Santa Cruz de la Sierra to San Francisco flight.

When to book flights from Santa Cruz de la Sierra to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to San Francisco (VVI to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to San Francisco

Fastest flight time

15h 37m

Direct flights

None
The fastest flight from Santa Cruz de la Sierra to San Francisco takes 15h 37m
There are no direct flights from Santa Cruz de la Sierra to San Francisco. There are no popular flight routes from Santa Cruz de la Sierra to San Francisco.
  • How far is Santa Cruz de la Sierra Viru Viru Intl to San Francisco by plane?

    San Francisco is 5428.9 mi away from Santa Cruz de la Sierra Viru Viru Intl. By plane, this route typically takes 15h 37m.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Cruz de la Sierra to San Francisco?

Best airlines flying from Santa Cruz de la Sierra to San Francisco

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $324Free CancellationRating
7.4
9,064 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $413Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
AviancaPriceFrom $706Free CancellationRating
6.6
2,478 reviews
Search Avianca flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Santa Clara
Berkeley
Walnut Creek
Daly City
Fremont
Half Moon Bay
Vallejo
Salinas
Livermore
Turlock
Sunnyvale

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Cruz de la Sierra to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Cruz de la Sierra to San Francisco with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Cruz de la Sierra to San Francisco flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Cruz de la Sierra to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Santa Cruz de la Sierra.

I’m not ready to book a flight from Santa Cruz de la Sierra to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Santa Cruz de la Sierra. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Fri 1/2
Fri 1/9

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