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Cheap flights from Santa Cruz de la Sierra to San Francisco from $480

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to San Francisco departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Cruz de la Sierra to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:47 am - 7:24 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
22h 37m2 stops Panama City Tocumen Intl Los Angeles
United Airlines Logo
5:41 pm - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
26h 03m2 stops Los Angeles Panama City Tocumen Intl
$890United Airlines
Sat, Aug 29 - Mon, Sep 21
United Airlines Logo
11:47 am - 7:24 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
22h 37m2 stops Panama City Tocumen Intl Los Angeles
United Airlines Logo
1:56 pm - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
29h 48m2 stops Los Angeles Panama City Tocumen Intl
$890United Airlines
Thu, Sep 3 - Wed, Sep 23
United Airlines Logo
11:47 am - 7:24 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
22h 37m2 stops Panama City Tocumen Intl Los Angeles
United Airlines Logo
12:38 pm - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
31h 06m2 stops Los Angeles Panama City Tocumen Intl
$890United Airlines
Thu, Sep 3 - Tue, Sep 22
United Airlines Logo
11:47 am - 8:17 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
35h 30m2 stops Panama City Tocumen Intl Los Angeles
United Airlines Logo
12:45 am - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
18h 59m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$890United Airlines
Mon, Aug 31 - Sat, Sep 19
Multiple Airlines Logo
11:47 am - 10:30 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
25h 43m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
Multiple Airlines Logo
12:45 am - 2:30 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
22h 45m2 stops Houston George Bush Intcntl Bogotá El Dorado
$898Multiple Airlines
Mon, Oct 5 - Thu, Oct 15
Multiple Airlines Logo
11:55 am - 6:02 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
33h 07m2 stops Panama City Tocumen Intl Los Angeles
Multiple Airlines Logo
11:59 pm - 2:30 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 31m2 stops Houston George Bush Intcntl Bogotá El Dorado
$899Multiple Airlines
Tue, Oct 27 - Wed, Mar 31
Multiple Airlines Logo
1:12 am - 10:42 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
36h 30m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
Multiple Airlines Logo
6:55 pm - 3:37 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
29h 42m2 stops Los Angeles Panama City Tocumen Intl
$919Multiple Airlines
Sat, Oct 3 - Sat, Oct 31
Copa Airlines Logo
11:47 am - 11:12 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
26h 25m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
Copa Airlines Logo
4:40 pm - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
51h 04m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$1,052Copa Airlines
Tue, Sep 1 - Fri, Sep 4
Copa Airlines Logo
11:47 am - 11:40 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
14h 53m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:21 pm - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 23m1 stop Panama City Tocumen Intl
$1,055Copa Airlines
Tue, Sep 1 - Wed, Sep 23
Copa Airlines Logo
1:12 am - 11:40 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
25h 28m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:31 am - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
18h 13m1 stop Panama City Tocumen Intl
$1,097Copa Airlines
Sat, Oct 3 - Fri, Oct 30

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Avianca flights from Santa Cruz de la Sierra to San Francisco

Our best Avianca deals on Santa Cruz de la Sierra to San Francisco flight tickets
Avianca
Oct 13
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
36h 15m
2 stops
SFO12:50 pmSan Francisco
Jan 16
SFO11:10 pmSan Francisco
23h 25m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
$1,109
Avianca
Oct 13
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
22h 00m
2 stops
SFO10:35 pmSan Francisco
Jan 14
SFO11:10 pmSan Francisco
47h 25m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
$1,126
Avianca
Oct 17
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
36h 15m
2 stops
SFO12:50 pmSan Francisco
Jan 15
SFO1:20 pmSan Francisco
33h 15m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
$1,147

United Airlines flights from Santa Cruz de la Sierra to San Francisco

Our best United Airlines deals on Santa Cruz de la Sierra to San Francisco flight tickets
United Airlines
Aug 29
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
24h 30m
2 stops
SFO9:17 amSan Francisco
Sep 24
SFO6:30 pmSan Francisco
30h 08m
2 stops
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
$890
United Airlines
Oct 15
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
38h 05m
2 stops
SFO10:52 pmSan Francisco
Oct 19
SFO9:30 pmSan Francisco
22h 14m
2 stops
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
$899
United Airlines
Oct 15
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
38h 05m
2 stops
SFO10:52 pmSan Francisco
Oct 19
SFO9:30 pmSan Francisco
22h 14m
2 stops
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
$900

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/29

11:47 am-7:24 am

2 stops22h 37m

San Francisco

Mon 9/21

5:41 pm-10:44 pm

2 stops26h 03m

$890

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/3

11:47 am-7:24 am

2 stops22h 37m

San Francisco

Wed 9/23

1:56 pm-10:44 pm

2 stops29h 48m

$890

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/3

11:47 am-7:24 am

2 stops22h 37m

San Francisco

Tue 9/22

12:38 pm-10:44 pm

2 stops31h 06m

$890

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/31

11:47 am-8:17 pm

2 stops35h 30m

San Francisco

Sat 9/19

12:45 am-10:44 pm

2 stops18h 59m

$890

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/5

11:47 am-10:30 am

2 stops25h 43m

San Francisco

Thu 10/15

12:45 am-2:30 am

2 stops22h 45m

$898

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

11:55 am-6:02 pm

2 stops33h 07m

San Francisco

Wed 3/31

11:59 pm-2:30 am

2 stops23h 31m

$899

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/3

1:12 am-10:42 am

2 stops36h 30m

San Francisco

Sat 10/31

6:55 pm-3:37 am

2 stops29h 42m

$919

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/1

11:47 am-11:12 am

2 stops26h 25m

San Francisco

Fri 9/4

4:40 pm-10:44 pm

2 stops51h 04m

$1,052
Quickest round-trip

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/1

11:47 am-11:40 pm

1 stop14h 53m

San Francisco

Wed 9/23

8:21 pm-10:44 pm

1 stop23h 23m

$1,055

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/3

1:12 am-11:40 pm

1 stop25h 28m

San Francisco

Fri 10/30

1:31 am-10:44 pm

1 stop18h 13m

$1,097

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santa Cruz de la Sierra to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Cruz de la Sierra and San Francisco?

Prices are currently typical for flights on this route.

Typical prices usually range from $834 to $1,205.
The lowest price recently found on this route was $890.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $805.

Can stopping save me money on Santa Cruz de la Sierra to San Francisco flights?

You could potentially save up to 6% on your flight if you consider stops on a Santa Cruz de la Sierra to San Francisco flight.

How have Santa Cruz de la Sierra to San Francisco flight prices changed over time?

When to book flights from Santa Cruz de la Sierra to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to San Francisco (VVI to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to San Francisco

Fastest flight time

22h 13m

Direct flights

None
The fastest flight from Santa Cruz de la Sierra to San Francisco takes 22h 13m
There are no direct flights from Santa Cruz de la Sierra to San Francisco. There are no popular flight routes from Santa Cruz de la Sierra to San Francisco.
Search flight deals

Frequently asked questions about flying from Santa Cruz de la Sierra to San Francisco

  • How far is Santa Cruz de la Sierra Viru Viru Intl to San Francisco by plane?

    San Francisco is 5428.0 mi away from Santa Cruz de la Sierra Viru Viru Intl. By plane, this route typically takes 22h 13m.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Cruz de la Sierra Viru Viru Intl Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Cruz de la Sierra to San Francisco?

Best airlines flying from Santa Cruz de la Sierra to San Francisco

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $299Free CancellationRating
7.4
10,112 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $455Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Fremont
Berkeley
Bodega Bay
Hayward
Walnut Creek
Santa Clara
Vallejo
Roseville
Sonoma
Salinas
Sunnyvale
Milpitas
Daly City
Burlingame
Marina
Palo Alto

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Cruz de la Sierra to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Cruz de la Sierra to San Francisco with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Cruz de la Sierra to San Francisco flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Cruz de la Sierra to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Santa Cruz de la Sierra.

I’m not ready to book a flight from Santa Cruz de la Sierra to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Santa Cruz de la Sierra. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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