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Cheap flights from Santa Ana to St. Louis from $101

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to St. Louis departing on 4/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Santa Ana to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:20 pm - 9:00 pm
SNA
-
STL
22h 40m
1 stop
Frontier Logo
9:55 pm - 6:11 pm
STL
-
SNA
22h 16m
1 stop
$210Frontier
Thu, May 7 - Sun, May 10
Frontier Logo
8:20 pm - 3:21 pm
SNA
-
STL
17h 01m
1 stop
Frontier Logo
9:55 pm - 6:11 pm
STL
-
SNA
22h 16m
1 stop
$211Frontier
Fri, May 8 - Sun, May 10
Frontier Logo
6:22 pm - 11:27 am
SNA
-
STL
15h 05m
1 stop
Frontier Logo
9:55 pm - 3:38 pm
STL
-
SNA
19h 43m
1 stop
$219Frontier
Thu, Apr 9 - Thu, Apr 16
Multiple Airlines Logo
2:53 pm - 9:48 am
SNA
-
STL
16h 55m
2 stops
Multiple Airlines Logo
10:12 pm - 9:53 am
STL
-
SNA
13h 41m
1 stop
$230Multiple Airlines
Tue, Mar 31 - Sun, Apr 5
Multiple Airlines Logo
6:45 am - 7:32 pm
SNA
-
STL
10h 47m
2 stops
Multiple Airlines Logo
8:06 pm - 11:25 am
STL
-
SNA
17h 19m
1 stop
$233Multiple Airlines
Sat, Apr 18 - Fri, Apr 24
Multiple Airlines Logo
2:53 pm - 9:48 am
SNA
-
STL
16h 55m
2 stops
Multiple Airlines Logo
10:12 pm - 7:35 pm
STL
-
SNA
23h 23m
1 stop
$239Multiple Airlines
Tue, Mar 31 - Thu, Apr 2
Multiple Airlines Logo
6:45 am - 3:21 pm
SNA
-
STL
6h 36m
1 stop
Multiple Airlines Logo
8:06 pm - 11:25 am
STL
-
SNA
17h 19m
1 stop
$252Multiple Airlines
Sat, Apr 18 - Fri, Apr 24
Multiple Airlines Logo
2:53 pm - 9:48 am
SNA
-
STL
16h 55m
2 stops
Multiple Airlines Logo
8:16 pm - 11:34 am
STL
-
SNA
17h 18m
1 stop
$260Multiple Airlines
Tue, Mar 31 - Sat, Apr 4
Multiple Airlines Logo
5:56 pm - 9:48 am
SNA
-
STL
13h 52m
2 stops
Multiple Airlines Logo
10:12 pm - 1:58 pm
STL
-
SNA
17h 46m
1 stop
$261Multiple Airlines
Fri, Apr 3 - Sun, Apr 5
Multiple Airlines Logo
7:56 pm - 9:10 pm
SNA
-
STL
23h 14m
1 stop
Multiple Airlines Logo
4:59 pm - 2:28 pm
STL
-
SNA
47h 29m
2 stops
$262Multiple Airlines
Thu, Apr 16 - Thu, Apr 23

Frontier flights from Santa Ana to St. Louis

Our best Frontier deals on Santa Ana to St. Louis flight tickets
Frontier
May 7
SNA8:20 pmSanta Ana J. Wayne/Orange Cnty
22h 40m
1 stop
STL9:00 pmLambert-St Louis
May 10
STL9:55 pmLambert-St Louis
22h 16m
1 stop
SNA6:11 pmSanta Ana J. Wayne/Orange Cnty
$210
Frontier
May 8
SNA8:20 pmSanta Ana J. Wayne/Orange Cnty
17h 01m
1 stop
STL3:21 pmLambert-St Louis
May 10
STL9:55 pmLambert-St Louis
22h 16m
1 stop
SNA6:11 pmSanta Ana J. Wayne/Orange Cnty
$211
Frontier
Apr 9
SNA6:22 pmSanta Ana J. Wayne/Orange Cnty
15h 05m
1 stop
STL11:27 amLambert-St Louis
Apr 16
STL9:55 pmLambert-St Louis
19h 43m
1 stop
SNA3:38 pmSanta Ana J. Wayne/Orange Cnty
$219

United Airlines flights from Santa Ana to St. Louis

Our best United Airlines deals on Santa Ana to St. Louis flight tickets
United Airlines
Apr 22
SNA1:21 pmSanta Ana J. Wayne/Orange Cnty
5h 33m
1 stop
STL8:54 pmLambert-St Louis
Apr 28
STL4:49 pmLambert-St Louis
6h 56m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
$317
United Airlines
Apr 22
SNA1:21 pmSanta Ana J. Wayne/Orange Cnty
5h 33m
1 stop
STL8:54 pmLambert-St Louis
Apr 28
STL9:10 amLambert-St Louis
10h 23m
2 stops
SNA5:33 pmSanta Ana J. Wayne/Orange Cnty
$322
United Airlines
Mar 26
SNA10:52 amSanta Ana J. Wayne/Orange Cnty
8h 23m
1 stop
STL9:15 pmLambert-St Louis
Mar 29
STL6:00 amLambert-St Louis
7h 13m
1 stop
SNA11:13 amSanta Ana J. Wayne/Orange Cnty
$647

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 5/7

8:20 pm-9:00 pm

1 stop22h 40m

Lambert-St Louis

Sun 5/10

9:55 pm-6:11 pm

1 stop22h 16m

$210

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 5/8

8:20 pm-3:21 pm

1 stop17h 01m

Lambert-St Louis

Sun 5/10

9:55 pm-6:11 pm

1 stop22h 16m

$211

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

6:22 pm-11:27 am

1 stop15h 05m

Lambert-St Louis

Thu 4/16

9:55 pm-3:38 pm

1 stop19h 43m

$219

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 3/31

2:53 pm-9:48 am

2 stops16h 55m

Lambert-St Louis

Sun 4/5

10:12 pm-9:53 am

1 stop13h 41m

$230

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 4/18

6:45 am-7:32 pm

2 stops10h 47m

Lambert-St Louis

Fri 4/24

8:06 pm-11:25 am

1 stop17h 19m

$233

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 3/31

2:53 pm-9:48 am

2 stops16h 55m

Lambert-St Louis

Thu 4/2

10:12 pm-7:35 pm

1 stop23h 23m

$239
Quickest round-trip

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 4/18

6:45 am-3:21 pm

1 stop6h 36m

Lambert-St Louis

Fri 4/24

8:06 pm-11:25 am

1 stop17h 19m

$252

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 3/31

2:53 pm-9:48 am

2 stops16h 55m

Lambert-St Louis

Sat 4/4

8:16 pm-11:34 am

1 stop17h 18m

$260

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 4/3

5:56 pm-9:48 am

2 stops13h 52m

Lambert-St Louis

Sun 4/5

10:12 pm-1:58 pm

1 stop17h 46m

$261

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 4/16

7:56 pm-9:10 pm

1 stop23h 14m

Lambert-St Louis

Thu 4/23

4:59 pm-2:28 pm

2 stops47h 29m

$262

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Santa Ana to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $326. The month of August is another great option to travel to St. Louis, with average flight prices from Santa Ana averaging around $331.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $384. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $447. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana in the evening is the least expensive time of day to depart. momondo users have found prices as low as $351 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $423 per ticket.

How have Santa Ana to St. Louis flight prices changed over time?

As of March 2026, prices for Santa Ana to St. Louis flights are approximately 22% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to St. Louis

Fastest flight time

5h 21m

Direct flights

None
The fastest flight from Santa Ana to St. Louis takes 5h 21m
There are no direct flights from Santa Ana to St. Louis. There are no popular flight routes from Santa Ana to St. Louis.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 21m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana to St. Louis?

Best airlines flying from Santa Ana to St. Louis

Compare and see reviews for airlines that fly from Santa Ana to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.7
3,031 reviews
Search Frontier flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,285 reviews
Search Delta flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,446 reviews
Search American Airlines flights
SouthwestPriceFrom $306Free CancellationRating
8.0
4,318 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,418 reviews
Search United Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Collinsville
St. Peters
Fenton
Alton
Wentzville
Farmington
Edwardsville
Festus
Clayton
Eureka
Litchfield
Glencoe
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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