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Cheap flights from Santa Ana, California to St. Louis from $81

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to St. Louis departing on 1/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana, California to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:58 am - 9:26 pm
SNA
-
STL
10h 28m1 stop
Frontier Logo
6:41 pm - 5:30 pm
STL
-
SNA
24h 49m1 stop
$145Frontier
Thu, Feb 12 - Sat, Feb 14
Multiple Airlines Logo
6:45 am - 9:06 pm
SNA
-
STL
12h 21m1 stop
Multiple Airlines Logo
3:46 pm - 11:32 am
STL
-
SNA
21h 46m1 stop
$148Multiple Airlines
Thu, Feb 5 - Sat, Feb 7
Multiple Airlines Logo
4:37 pm - 9:06 pm
SNA
-
STL
26h 29m1 stop
Multiple Airlines Logo
9:45 pm - 12:25 pm
STL
-
SNA
16h 40m1 stop
$150Multiple Airlines
Wed, Feb 4 - Mon, Feb 9
Multiple Airlines Logo
4:37 pm - 9:06 pm
SNA
-
STL
26h 29m1 stop
Multiple Airlines Logo
9:32 pm - 6:01 pm
STL
-
SNA
22h 29m1 stop
$154Multiple Airlines
Wed, Feb 4 - Sun, Feb 8
Multiple Airlines Logo
6:45 am - 8:48 pm
SNA
-
STL
12h 03m1 stop
Multiple Airlines Logo
9:45 pm - 12:25 pm
STL
-
SNA
16h 40m1 stop
$156Multiple Airlines
Fri, Jan 30 - Mon, Feb 2
Multiple Airlines Logo
6:45 am - 5:46 pm
SNA
-
STL
9h 01m1 stop
Multiple Airlines Logo
10:11 pm - 8:13 am
STL
-
SNA
12h 02m1 stop
$160Multiple Airlines
Sat, Feb 21 - Sun, Mar 1
Multiple Airlines Logo
6:45 am - 5:46 pm
SNA
-
STL
9h 01m1 stop
Multiple Airlines Logo
10:11 pm - 8:13 am
STL
-
SNA
12h 02m1 stop
$161Multiple Airlines
Sat, Feb 21 - Sun, Mar 1
Multiple Airlines Logo
6:45 am - 8:50 pm
SNA
-
STL
12h 05m1 stop
Multiple Airlines Logo
9:45 pm - 3:42 pm
STL
-
SNA
19h 57m1 stop
$170Multiple Airlines
Mon, Feb 2 - Mon, Feb 9
Multiple Airlines Logo
6:45 am - 8:50 pm
SNA
-
STL
12h 05m1 stop
Multiple Airlines Logo
9:32 pm - 6:01 pm
STL
-
SNA
22h 29m1 stop
$174Multiple Airlines
Mon, Feb 2 - Sun, Feb 8
Frontier Logo
8:58 am - 9:26 pm
SNA
-
STL
10h 28m1 stop
Frontier Logo
1:59 pm - 11:40 am
STL
-
SNA
23h 41m1 stop
$178Frontier
Thu, Feb 19 - Fri, Feb 20

Frontier flights from Santa Ana, California to St. Louis

Our best Frontier deals on Santa Ana, California to St. Louis flight tickets
Frontier
Feb 12
SNA8:58 amSanta Ana J. Wayne/Orange Cnty
10h 28m
1 stop
STL9:26 pmLambert-St Louis
Feb 14
STL6:41 pmLambert-St Louis
24h 49m
1 stop
SNA5:30 pmSanta Ana J. Wayne/Orange Cnty
$145
Frontier
Feb 19
SNA8:58 amSanta Ana J. Wayne/Orange Cnty
10h 28m
1 stop
STL9:26 pmLambert-St Louis
Feb 20
STL1:59 pmLambert-St Louis
23h 41m
1 stop
SNA11:40 amSanta Ana J. Wayne/Orange Cnty
$178
Frontier
Feb 5
SNA2:39 pmSanta Ana J. Wayne/Orange Cnty
28h 09m
1 stop
STL8:48 pmLambert-St Louis
Feb 12
STL10:11 pmLambert-St Louis
19h 06m
1 stop
SNA3:17 pmSanta Ana J. Wayne/Orange Cnty
$202

Alaska Airlines flights from Santa Ana, California to St. Louis

Our best Alaska Airlines deals on Santa Ana, California to St. Louis flight tickets
Alaska Airlines
Jan 28
SNA12:33 pmSanta Ana J. Wayne/Orange Cnty
23h 21m
1 stop
STL1:54 pmLambert-St Louis
Jan 31
STL6:19 pmLambert-St Louis
17h 46m
1 stop
SNA10:05 amSanta Ana J. Wayne/Orange Cnty
$282
Alaska Airlines
Feb 19
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
15h 14m
1 stop
STL11:59 pmLambert-St Louis
Feb 23
STL2:47 pmLambert-St Louis
21h 41m
1 stop
SNA10:28 amSanta Ana J. Wayne/Orange Cnty
$289
Alaska Airlines
Jan 28
SNA3:35 pmSanta Ana J. Wayne/Orange Cnty
20h 19m
1 stop
STL1:54 pmLambert-St Louis
Jan 30
STL2:50 pmLambert-St Louis
19h 46m
2 stops
SNA8:36 amSanta Ana J. Wayne/Orange Cnty
$292

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Santa Ana, California to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 2/12

8:58 am-9:26 pm

1 stop10h 28m

Lambert-St Louis

Sat 2/14

6:41 pm-5:30 pm

1 stop24h 49m

$145

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

6:45 am-9:06 pm

1 stop12h 21m

Lambert-St Louis

Sat 2/7

3:46 pm-11:32 am

1 stop21h 46m

$148

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

4:37 pm-9:06 pm

1 stop26h 29m

Lambert-St Louis

Mon 2/9

9:45 pm-12:25 pm

1 stop16h 40m

$150

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

4:37 pm-9:06 pm

1 stop26h 29m

Lambert-St Louis

Sun 2/8

9:32 pm-6:01 pm

1 stop22h 29m

$154

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 1/30

6:45 am-8:48 pm

1 stop12h 03m

Lambert-St Louis

Mon 2/2

9:45 pm-12:25 pm

1 stop16h 40m

$156

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 2/21

6:45 am-5:46 pm

1 stop9h 01m

Lambert-St Louis

Sun 3/1

10:11 pm-8:13 am

1 stop12h 02m

$160

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 2/21

6:45 am-5:46 pm

1 stop9h 01m

Lambert-St Louis

Sun 3/1

10:11 pm-8:13 am

1 stop12h 02m

$161

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

6:45 am-8:50 pm

1 stop12h 05m

Lambert-St Louis

Mon 2/9

9:45 pm-3:42 pm

1 stop19h 57m

$170

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

6:45 am-8:50 pm

1 stop12h 05m

Lambert-St Louis

Sun 2/8

9:32 pm-6:01 pm

1 stop22h 29m

$174

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 2/19

8:58 am-9:26 pm

1 stop10h 28m

Lambert-St Louis

Fri 2/20

1:59 pm-11:40 am

1 stop23h 41m

$178

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana, California to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Santa Ana, California to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $329. The month of August is another great option to travel to St. Louis, with average flight prices from Santa Ana, California averaging around $374.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $390. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $426. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana, California in the evening is the least expensive time of day to depart. momondo users have found prices as low as $351 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $409 per ticket.

How have Santa Ana, California to St. Louis flight prices changed over time?

As of January 2026, prices for Santa Ana, California to St. Louis flights are approximately 62% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to St. Louis

Fastest flight time

5h 10m

Direct flights

None
The fastest flight from Santa Ana, California to St. Louis takes 5h 10m
There are no direct flights from Santa Ana, California to St. Louis. There are no popular flight routes from Santa Ana, California to St. Louis.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 10m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana, California to St. Louis?

Best airlines flying from Santa Ana, California to St. Louis

Compare and see reviews for airlines that fly from Santa Ana, California to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.7
3,062 reviews
Search Frontier flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,025 reviews
Search Delta flights
American AirlinesPriceFrom $278Free CancellationRating
7.2
11,095 reviews
Search American Airlines flights
SouthwestPriceFrom $306Free CancellationRating
8.0
4,250 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,139 reviews
Search United Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
O'Fallon
Maryland Heights
Florissant
Fenton
Collinsville
St. Peters
Wentzville
Alton
Farmington
Clayton
Eureka
Festus
Edwardsville
Glencoe
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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