Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santa Ana, California to St. Louis from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to St. Louis departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santa Ana, California to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:14 pm - 8:23 pm
SNA
-
STL
22h 09m
1 stop
Frontier Logo
12:36 pm - 12:19 pm
STL
-
SNA
25h 43m
1 stop
$160Frontier
Thu, May 7 - Sun, May 10
Multiple Airlines Logo
7:30 am - 6:06 pm
SNA
-
STL
8h 36m
1 stop
Multiple Airlines Logo
6:51 pm - 12:19 pm
STL
-
SNA
19h 28m
1 stop
$225Multiple Airlines
Tue, May 5 - Wed, May 6
Multiple Airlines Logo
4:33 pm - 7:23 pm
SNA
-
STL
24h 50m
2 stops
Multiple Airlines Logo
8:08 pm - 9:09 am
STL
-
SNA
15h 01m
1 stop
$233Multiple Airlines
Wed, May 20 - Wed, Jun 3
Multiple Airlines Logo
7:45 am - 6:06 pm
SNA
-
STL
8h 21m
1 stop
Multiple Airlines Logo
8:08 pm - 9:09 am
STL
-
SNA
15h 01m
1 stop
$240Multiple Airlines
Wed, May 20 - Wed, Jun 3
Multiple Airlines Logo
7:30 am - 6:06 pm
SNA
-
STL
8h 36m
1 stop
Multiple Airlines Logo
6:51 pm - 11:28 am
STL
-
SNA
18h 37m
2 stops
$243Multiple Airlines
Tue, May 5 - Wed, May 6
Multiple Airlines Logo
7:30 am - 6:06 pm
SNA
-
STL
8h 36m
1 stop
Multiple Airlines Logo
12:36 pm - 12:19 pm
STL
-
SNA
25h 43m
1 stop
$252Multiple Airlines
Tue, May 5 - Thu, May 7
Multiple Airlines Logo
7:45 am - 6:06 pm
SNA
-
STL
8h 21m
1 stop
Multiple Airlines Logo
12:36 pm - 12:19 pm
STL
-
SNA
25h 43m
1 stop
$254Multiple Airlines
Wed, May 6 - Thu, May 7
Multiple Airlines Logo
7:45 am - 6:06 pm
SNA
-
STL
8h 21m
1 stop
Multiple Airlines Logo
6:51 pm - 3:38 pm
STL
-
SNA
22h 47m
1 stop
$263Multiple Airlines
Tue, May 12 - Tue, May 26
Frontier Logo
9:54 am - 7:23 pm
SNA
-
STL
7h 29m
1 stop
Frontier Logo
9:06 pm - 9:09 am
STL
-
SNA
14h 03m
2 stops
$272Frontier
Thu, May 28 - Sun, May 31
Multiple Airlines Logo
4:33 pm - 7:23 pm
SNA
-
STL
24h 50m
2 stops
Multiple Airlines Logo
6:51 pm - 3:38 pm
STL
-
SNA
22h 47m
1 stop
$280Multiple Airlines
Wed, May 13 - Tue, May 19

Frontier flights from Santa Ana, California to St. Louis

Our best Frontier deals on Santa Ana, California to St. Louis flight tickets
Frontier
May 7
SNA8:14 pmSanta Ana J. Wayne/Orange Cnty
22h 09m
1 stop
STL8:23 pmLambert-St Louis
May 10
STL12:36 pmLambert-St Louis
25h 43m
1 stop
SNA12:19 pmSanta Ana J. Wayne/Orange Cnty
$160
Frontier
Apr 30
SNA11:29 amSanta Ana J. Wayne/Orange Cnty
5h 52m
1 stop
STL7:21 pmLambert-St Louis
May 3
STL9:55 pmLambert-St Louis
19h 06m
1 stop
SNA3:01 pmSanta Ana J. Wayne/Orange Cnty
$255
Frontier
May 28
SNA9:54 amSanta Ana J. Wayne/Orange Cnty
7h 29m
1 stop
STL7:23 pmLambert-St Louis
May 31
STL9:06 pmLambert-St Louis
14h 03m
2 stops
SNA9:09 amSanta Ana J. Wayne/Orange Cnty
$272

Delta flights from Santa Ana, California to St. Louis

Our best Delta deals on Santa Ana, California to St. Louis flight tickets
Delta
Apr 29
SNA11:54 amSanta Ana J. Wayne/Orange Cnty
9h 42m
1 stop
STL11:36 pmLambert-St Louis
May 6
STL2:20 pmLambert-St Louis
5h 44m
1 stop
SNA6:04 pmSanta Ana J. Wayne/Orange Cnty
$482
Delta
Apr 30
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
6h 47m
1 stop
STL3:32 pmLambert-St Louis
May 5
STL7:00 amLambert-St Louis
12h 53m
2 stops
SNA5:53 pmSanta Ana J. Wayne/Orange Cnty
$521
Delta
Apr 30
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
6h 47m
1 stop
STL3:32 pmLambert-St Louis
May 4
STL7:00 amLambert-St Louis
7h 09m
1 stop
SNA12:09 pmSanta Ana J. Wayne/Orange Cnty
$577

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Santa Ana, California to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 5/7

8:14 pm-8:23 pm

1 stop22h 09m

Lambert-St Louis

Sun 5/10

12:36 pm-12:19 pm

1 stop25h 43m

$160

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

7:30 am-6:06 pm

1 stop8h 36m

Lambert-St Louis

Wed 5/6

6:51 pm-12:19 pm

1 stop19h 28m

$225

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 5/20

4:33 pm-7:23 pm

2 stops24h 50m

Lambert-St Louis

Wed 6/3

8:08 pm-9:09 am

1 stop15h 01m

$233

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 5/20

7:45 am-6:06 pm

1 stop8h 21m

Lambert-St Louis

Wed 6/3

8:08 pm-9:09 am

1 stop15h 01m

$240

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

7:30 am-6:06 pm

1 stop8h 36m

Lambert-St Louis

Wed 5/6

6:51 pm-11:28 am

2 stops18h 37m

$243

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

7:30 am-6:06 pm

1 stop8h 36m

Lambert-St Louis

Thu 5/7

12:36 pm-12:19 pm

1 stop25h 43m

$252

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

7:45 am-6:06 pm

1 stop8h 21m

Lambert-St Louis

Thu 5/7

12:36 pm-12:19 pm

1 stop25h 43m

$254

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 5/12

7:45 am-6:06 pm

1 stop8h 21m

Lambert-St Louis

Tue 5/26

6:51 pm-3:38 pm

1 stop22h 47m

$263
Quickest round-trip

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 5/28

9:54 am-7:23 pm

1 stop7h 29m

Lambert-St Louis

Sun 5/31

9:06 pm-9:09 am

2 stops14h 03m

$272

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 5/13

4:33 pm-7:23 pm

2 stops24h 50m

Lambert-St Louis

Tue 5/19

6:51 pm-3:38 pm

1 stop22h 47m

$280

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana, California to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Santa Ana, California to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $326. The month of August is another great option to travel to St. Louis, with average flight prices from Santa Ana, California averaging around $331.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $391. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $509. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana, California in the evening is the least expensive time of day to depart. momondo users have found prices as low as $334 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $475 per ticket.

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from Santa Ana, California when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $441 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Santa Ana, California for as low as $329 on momondo.

How have Santa Ana, California to St. Louis flight prices changed over time?

As of April 2026, prices for Santa Ana, California to St. Louis flights are approximately 86% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana, California to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to St. Louis

Fastest flight time

5h 57m

Direct flights

None
The fastest flight from Santa Ana, California to St. Louis takes 5h 57m
There are no direct flights from Santa Ana, California to St. Louis. There are no popular flight routes from Santa Ana, California to St. Louis.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to St. Louis

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 57m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana, California to St. Louis?

Best airlines flying from Santa Ana, California to St. Louis

Compare and see reviews for airlines that fly from Santa Ana, California to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.7
2,987 reviews
Search Frontier flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,424 reviews
Search Delta flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,604 reviews
Search American Airlines flights
SouthwestPriceFrom $306Free CancellationRating
8.0
4,330 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,605 reviews
Search United Airlines flights

  • Southwest Flights From Santa Ana, California to St. Louis

    Southwest flies from Santa Ana, California to St. Louis around 3 times per week, with 4,330 momondo users rating the airline 8.0/10. The cheapest Southwest deal from Santa Ana, California to St. Louis in the last 72 hours was $306 (round-trip), much lower than the average airfare cost of $466 for Southwest flights on this route.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
St. Peters
Collinsville
Wentzville
Alton
Fenton
Farmington
Festus
Clayton
Eureka
Litchfield
Edwardsville
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 5/18
Mon 5/25
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States