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Cheap flights from Santa Ana, California to St. Louis from $135

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to St. Louis departing on 10/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
9:39 am - 7:13 pm
SNA
-
STL
7h 34m
1 stop
Frontier Logo
6:17 pm - 1:42 pm
STL
-
SNA
21h 25m
2 stops
$272Frontier
Thu, Aug 27 - Sun, Aug 30
Frontier Logo
2:27 pm - 9:40 am
SNA
-
STL
17h 13m
2 stops
Frontier Logo
8:10 pm - 10:12 am
STL
-
SNA
16h 02m
1 stop
$278Frontier
Mon, Sep 14 - Thu, Sep 17
Frontier Logo
4:50 pm - 11:51 am
SNA
-
STL
17h 01m
1 stop
Frontier Logo
8:10 pm - 10:12 am
STL
-
SNA
16h 02m
1 stop
$282Frontier
Mon, Sep 14 - Thu, Sep 17
Frontier Logo
4:13 pm - 7:23 pm
SNA
-
STL
25h 10m
2 stops
Frontier Logo
6:45 pm - 12:31 pm
STL
-
SNA
19h 46m
1 stop
$283Frontier
Tue, Aug 11 - Thu, Aug 27
Frontier Logo
9:39 am - 7:13 pm
SNA
-
STL
7h 34m
1 stop
Frontier Logo
6:45 pm - 12:31 pm
STL
-
SNA
19h 46m
1 stop
$293Frontier
Thu, Aug 27 - Sun, Aug 30
Frontier Logo
2:27 pm - 7:23 pm
SNA
-
STL
26h 56m
2 stops
Frontier Logo
7:10 pm - 12:31 pm
STL
-
SNA
19h 21m
1 stop
$295Frontier
Mon, Aug 10 - Sun, Aug 16
Multiple Airlines Logo
7:30 am - 6:15 pm
SNA
-
STL
8h 45m
1 stop
Multiple Airlines Logo
8:08 pm - 8:05 am
STL
-
SNA
13h 57m
1 stop
$296Multiple Airlines
Thu, Aug 6 - Thu, Aug 13
Multiple Airlines Logo
9:39 am - 7:13 pm
SNA
-
STL
7h 34m
1 stop
Multiple Airlines Logo
7:58 pm - 3:01 pm
STL
-
SNA
21h 03m
2 stops
$298Multiple Airlines
Thu, Aug 27 - Mon, Aug 31
Frontier Logo
9:39 am - 7:13 pm
SNA
-
STL
7h 34m
1 stop
Frontier Logo
6:45 pm - 12:31 pm
STL
-
SNA
19h 46m
1 stop
$299Frontier
Thu, Aug 27 - Sun, Aug 30
Multiple Airlines Logo
9:39 am - 7:13 pm
SNA
-
STL
7h 34m
1 stop
Multiple Airlines Logo
6:45 pm - 3:01 pm
STL
-
SNA
22h 16m
1 stop
$300Multiple Airlines
Thu, Aug 27 - Mon, Aug 31

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Delta flights from Santa Ana, California to St. Louis

Our best Delta deals on Santa Ana, California to St. Louis flight tickets
Delta
Aug 11
SNA5:04 pmSanta Ana J. Wayne/Orange Cnty
5h 37m
1 stop
STL12:41 amLambert-St Louis
Aug 14
STL6:20 amLambert-St Louis
8h 34m
1 stop
SNA12:54 pmSanta Ana J. Wayne/Orange Cnty
$323
Delta
Aug 11
SNA5:04 pmSanta Ana J. Wayne/Orange Cnty
5h 37m
1 stop
STL12:41 amLambert-St Louis
Aug 17
STL3:50 pmLambert-St Louis
6h 17m
1 stop
SNA8:07 pmSanta Ana J. Wayne/Orange Cnty
$337
Delta
Aug 10
SNA5:04 pmSanta Ana J. Wayne/Orange Cnty
5h 37m
1 stop
STL12:41 amLambert-St Louis
Aug 18
STL2:32 pmLambert-St Louis
5h 50m
1 stop
SNA6:22 pmSanta Ana J. Wayne/Orange Cnty
$362

Frontier flights from Santa Ana, California to St. Louis

Our best Frontier deals on Santa Ana, California to St. Louis flight tickets
Frontier
Aug 27
SNA9:39 amSanta Ana J. Wayne/Orange Cnty
7h 34m
1 stop
STL7:13 pmLambert-St Louis
Aug 30
STL6:17 pmLambert-St Louis
21h 25m
2 stops
SNA1:42 pmSanta Ana J. Wayne/Orange Cnty
$272
Frontier
Sep 14
SNA2:27 pmSanta Ana J. Wayne/Orange Cnty
17h 13m
2 stops
STL9:40 amLambert-St Louis
Sep 17
STL8:10 pmLambert-St Louis
16h 02m
1 stop
SNA10:12 amSanta Ana J. Wayne/Orange Cnty
$278
Frontier
Sep 14
SNA4:50 pmSanta Ana J. Wayne/Orange Cnty
17h 01m
1 stop
STL11:51 amLambert-St Louis
Sep 17
STL8:10 pmLambert-St Louis
16h 02m
1 stop
SNA10:12 amSanta Ana J. Wayne/Orange Cnty
$282

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from Santa Ana, California to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

9:39 am-7:13 pm

1 stop7h 34m

Lambert-St Louis

Sun 8/30

6:17 pm-1:42 pm

2 stops21h 25m

$272

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 9/14

2:27 pm-9:40 am

2 stops17h 13m

Lambert-St Louis

Thu 9/17

8:10 pm-10:12 am

1 stop16h 02m

$278

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 9/14

4:50 pm-11:51 am

1 stop17h 01m

Lambert-St Louis

Thu 9/17

8:10 pm-10:12 am

1 stop16h 02m

$282

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 8/11

4:13 pm-7:23 pm

2 stops25h 10m

Lambert-St Louis

Thu 8/27

6:45 pm-12:31 pm

1 stop19h 46m

$283

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

9:39 am-7:13 pm

1 stop7h 34m

Lambert-St Louis

Sun 8/30

6:45 pm-12:31 pm

1 stop19h 46m

$293

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 8/10

2:27 pm-7:23 pm

2 stops26h 56m

Lambert-St Louis

Sun 8/16

7:10 pm-12:31 pm

1 stop19h 21m

$295
Quickest round-trip

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 8/6

7:30 am-6:15 pm

1 stop8h 45m

Lambert-St Louis

Thu 8/13

8:08 pm-8:05 am

1 stop13h 57m

$296

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

9:39 am-7:13 pm

1 stop7h 34m

Lambert-St Louis

Mon 8/31

7:58 pm-3:01 pm

2 stops21h 03m

$298

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

9:39 am-7:13 pm

1 stop7h 34m

Lambert-St Louis

Sun 8/30

6:45 pm-12:31 pm

1 stop19h 46m

$299

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

9:39 am-7:13 pm

1 stop7h 34m

Lambert-St Louis

Mon 8/31

6:45 pm-3:01 pm

1 stop22h 16m

$300

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana, California to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Santa Ana, California to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $324. The month of February is another great option to travel to St. Louis, with average flight prices from Santa Ana, California averaging around $422.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $408. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $549. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana, California in the evening is the least expensive time of day to depart. momondo users have found prices as low as $331 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $560 per ticket.

How have Santa Ana, California to St. Louis flight prices changed over time?

As of July 2026, prices for Santa Ana, California to St. Louis flights are approximately 59% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana, California to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to St. Louis

Fastest flight time

5h 57m

Direct flights

None
The fastest flight from Santa Ana, California to St. Louis takes 5h 57m
There are no direct flights from Santa Ana, California to St. Louis. There are no popular flight routes from Santa Ana, California to St. Louis.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to St. Louis

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 57m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana, California to St. Louis?

Best airlines flying from Santa Ana, California to St. Louis

Compare and see reviews for airlines that fly from Santa Ana, California to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $129Free CancellationRating
5.6
2,816 reviews
Search Frontier flights
DeltaPriceFrom $276Free CancellationRating
7.8
8,462 reviews
Search Delta flights
SouthwestPriceFrom $311Free CancellationRating
8.0
4,249 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,983 reviews
Search United Airlines flights
American AirlinesPriceFrom $317Free CancellationRating
7.1
11,811 reviews
Search American Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
Collinsville
Florissant
St. Peters
Maryland Heights
O'Fallon
Alton
Farmington
Wentzville
Clayton
Fenton
Festus
Eureka
Edwardsville
Litchfield
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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