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Cheap flights from Santa Ana, California to St. Louis from $82

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to St. Louis departing on 4/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:19 pm - 9:48 am
SNA
-
STL
19h 29m
1 stop
Multiple Airlines Logo
8:19 pm - 9:13 pm
STL
-
SNA
26h 54m
2 stops
$201Multiple Airlines
Thu, Apr 9 - Mon, Apr 13
Frontier Logo
8:59 pm - 7:32 pm
SNA
-
STL
20h 33m
2 stops
Frontier Logo
8:06 pm - 11:25 am
STL
-
SNA
17h 19m
1 stop
$209Frontier
Fri, Apr 17 - Fri, Apr 24
Multiple Airlines Logo
7:30 am - 9:00 pm
SNA
-
STL
11h 30m
1 stop
Multiple Airlines Logo
8:17 pm - 10:44 am
STL
-
SNA
16h 27m
1 stop
$210Multiple Airlines
Thu, Apr 16 - Sat, Apr 18
Multiple Airlines Logo
9:00 am - 9:10 pm
SNA
-
STL
10h 10m
1 stop
Multiple Airlines Logo
9:55 pm - 8:05 am
STL
-
SNA
12h 10m
1 stop
$213Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
1:12 pm - 11:19 am
SNA
-
STL
20h 07m
1 stop
Multiple Airlines Logo
12:17 pm - 9:53 am
STL
-
SNA
23h 36m
1 stop
$220Multiple Airlines
Mon, Mar 30 - Mon, Apr 6
Multiple Airlines Logo
6:45 am - 9:10 pm
SNA
-
STL
12h 25m
1 stop
Multiple Airlines Logo
8:06 pm - 11:25 am
STL
-
SNA
17h 19m
1 stop
$225Multiple Airlines
Fri, Apr 17 - Fri, Apr 24
Multiple Airlines Logo
3:23 pm - 7:12 pm
SNA
-
STL
25h 49m
2 stops
Multiple Airlines Logo
8:12 pm - 10:46 am
STL
-
SNA
16h 34m
1 stop
$230Multiple Airlines
Wed, May 6 - Sat, May 9
Multiple Airlines Logo
6:02 pm - 11:27 am
SNA
-
STL
15h 25m
1 stop
Multiple Airlines Logo
10:12 pm - 4:20 pm
STL
-
SNA
20h 08m
1 stop
$232Multiple Airlines
Thu, Apr 2 - Sun, Apr 5
Multiple Airlines Logo
9:00 am - 9:00 pm
SNA
-
STL
10h 00m
1 stop
Multiple Airlines Logo
9:55 pm - 5:56 pm
STL
-
SNA
22h 01m
1 stop
$233Multiple Airlines
Thu, Apr 23 - Sun, Apr 26
Multiple Airlines Logo
5:28 pm - 3:21 pm
SNA
-
STL
19h 53m
2 stops
Multiple Airlines Logo
9:55 pm - 8:05 am
STL
-
SNA
12h 10m
1 stop
$244Multiple Airlines
Fri, Apr 17 - Sun, Apr 19

Frontier flights from Santa Ana, California to St. Louis

Our best Frontier deals on Santa Ana, California to St. Louis flight tickets
Frontier
Apr 17
SNA8:59 pmSanta Ana J. Wayne/Orange Cnty
20h 33m
2 stops
STL7:32 pmLambert-St Louis
Apr 24
STL8:06 pmLambert-St Louis
17h 19m
1 stop
SNA11:25 amSanta Ana J. Wayne/Orange Cnty
$209
Frontier
Apr 20
SNA2:41 pmSanta Ana J. Wayne/Orange Cnty
30h 38m
2 stops
STL11:19 pmLambert-St Louis
Apr 25
STL8:17 pmLambert-St Louis
16h 27m
1 stop
SNA10:44 amSanta Ana J. Wayne/Orange Cnty
$245
Frontier
Apr 20
SNA2:41 pmSanta Ana J. Wayne/Orange Cnty
30h 38m
2 stops
STL11:19 pmLambert-St Louis
Apr 25
STL8:17 pmLambert-St Louis
16h 27m
1 stop
SNA10:44 amSanta Ana J. Wayne/Orange Cnty
$246

United Airlines flights from Santa Ana, California to St. Louis

Our best United Airlines deals on Santa Ana, California to St. Louis flight tickets
United Airlines
Apr 21
SNA1:21 pmSanta Ana J. Wayne/Orange Cnty
5h 33m
1 stop
STL8:54 pmLambert-St Louis
Apr 25
STL6:00 amLambert-St Louis
9h 36m
1 stop
SNA1:36 pmSanta Ana J. Wayne/Orange Cnty
$303
United Airlines
Mar 13
SNA8:49 amSanta Ana J. Wayne/Orange Cnty
10h 18m
2 stops
STL9:07 pmLambert-St Louis
Mar 16
STL5:55 pmLambert-St Louis
6h 20m
1 stop
SNA10:15 pmSanta Ana J. Wayne/Orange Cnty
$739
United Airlines
Mar 13
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
9h 00m
2 stops
STL6:00 pmLambert-St Louis
Mar 16
STL7:00 amLambert-St Louis
12h 28m
1 stop
SNA5:28 pmSanta Ana J. Wayne/Orange Cnty
$866

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Santa Ana, California to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

12:19 pm-9:48 am

1 stop19h 29m

Lambert-St Louis

Mon 4/13

8:19 pm-9:13 pm

2 stops26h 54m

$201

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 4/17

8:59 pm-7:32 pm

2 stops20h 33m

Lambert-St Louis

Fri 4/24

8:06 pm-11:25 am

1 stop17h 19m

$209

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 4/16

7:30 am-9:00 pm

1 stop11h 30m

Lambert-St Louis

Sat 4/18

8:17 pm-10:44 am

1 stop16h 27m

$210

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 4/17

9:00 am-9:10 pm

1 stop10h 10m

Lambert-St Louis

Sun 4/19

9:55 pm-8:05 am

1 stop12h 10m

$213

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

1:12 pm-11:19 am

1 stop20h 07m

Lambert-St Louis

Mon 4/6

12:17 pm-9:53 am

1 stop23h 36m

$220

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 4/17

6:45 am-9:10 pm

1 stop12h 25m

Lambert-St Louis

Fri 4/24

8:06 pm-11:25 am

1 stop17h 19m

$225

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

3:23 pm-7:12 pm

2 stops25h 49m

Lambert-St Louis

Sat 5/9

8:12 pm-10:46 am

1 stop16h 34m

$230

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 4/2

6:02 pm-11:27 am

1 stop15h 25m

Lambert-St Louis

Sun 4/5

10:12 pm-4:20 pm

1 stop20h 08m

$232

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 4/23

9:00 am-9:00 pm

1 stop10h 00m

Lambert-St Louis

Sun 4/26

9:55 pm-5:56 pm

1 stop22h 01m

$233

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 4/17

5:28 pm-3:21 pm

2 stops19h 53m

Lambert-St Louis

Sun 4/19

9:55 pm-8:05 am

1 stop12h 10m

$244

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana, California to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Santa Ana, California to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $326. The month of August is another great option to travel to St. Louis, with average flight prices from Santa Ana, California averaging around $331.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $384. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $447. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana, California in the evening is the least expensive time of day to depart. momondo users have found prices as low as $351 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $425 per ticket.

How have Santa Ana, California to St. Louis flight prices changed over time?

As of March 2026, prices for Santa Ana, California to St. Louis flights are approximately 32% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana, California to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to St. Louis

Fastest flight time

5h 31m

Direct flights

None
The fastest flight from Santa Ana, California to St. Louis takes 5h 31m
There are no direct flights from Santa Ana, California to St. Louis. There are no popular flight routes from Santa Ana, California to St. Louis.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 31m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana, California to St. Louis?

Best airlines flying from Santa Ana, California to St. Louis

Compare and see reviews for airlines that fly from Santa Ana, California to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.7
3,041 reviews
Search Frontier flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,245 reviews
Search Delta flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,378 reviews
Search American Airlines flights
SouthwestPriceFrom $302Free CancellationRating
8.0
4,304 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,382 reviews
Search United Airlines flights

  • United Airlines Flights From Santa Ana, California to St. Louis

    United Airlines flies from Santa Ana, California to St. Louis around 1 time per week, with 9,382 momondo users rating the airline 7.4/10. The cheapest United Airlines deal from Santa Ana, California to St. Louis in the last 72 hours was $311 (round-trip), much lower than the average airfare cost of $442 for United Airlines flights on this route.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
St. Peters
Wentzville
Collinsville
Alton
Fenton
Farmington
Edwardsville
Festus
Clayton
Eureka
Litchfield
Glencoe
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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