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Cheap flights from Santa Ana, California to St. Louis from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to St. Louis departing on 12/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:45 am - 8:50 pmSNA-STL
11h 05m1 stop
Multiple Airlines Logo
3:46 pm - 10:58 amSTL-SNA
21h 12m1 stop
$164Multiple Airlines
Find Deal
Mon, Jan 26 - Wed, Jan 28
Frontier Logo
11:15 am - 10:14 amSNA-STL
20h 59m1 stop
Frontier Logo
7:43 pm - 12:42 pmSTL-SNA
18h 59m1 stop
$182Frontier
Find Deal
Thu, Dec 11 - Mon, Dec 15
Frontier Logo
12:17 pm - 2:46 pmSNA-STL
24h 29m1 stop
Frontier Logo
1:03 pm - 9:12 amSTL-SNA
22h 09m1 stop
$186Frontier
Find Deal
Fri, Jan 23 - Sun, Jan 25
Frontier Logo
10:07 am - 8:50 pmSNA-STL
8h 43m2 stops
Frontier Logo
3:46 pm - 10:58 amSTL-SNA
21h 12m1 stop
$199Frontier
Find Deal
Mon, Jan 26 - Wed, Jan 28
Multiple Airlines Logo
7:45 am - 8:48 pmSNA-STL
11h 03m1 stop
Multiple Airlines Logo
9:27 pm - 12:25 pmSTL-SNA
16h 58m1 stop
$202Multiple Airlines
Find Deal
Fri, Jan 23 - Sun, Jan 25
Frontier Logo
1:35 pm - 10:14 amSNA-STL
18h 39m1 stop
Frontier Logo
1:16 pm - 5:39 pmSTL-SNA
6h 23m1 stop
$207Frontier
Find Deal
Fri, Dec 5 - Mon, Dec 8
Multiple Airlines Logo
8:19 pm - 12:12 pmSNA-STL
13h 53m1 stop
Multiple Airlines Logo
1:16 pm - 10:44 amSTL-SNA
23h 28m1 stop
$214Multiple Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15
Multiple Airlines Logo
7:45 am - 8:48 pmSNA-STL
11h 03m1 stop
Multiple Airlines Logo
9:27 pm - 2:11 pmSTL-SNA
18h 44m2 stops
$237Multiple Airlines
Find Deal
Fri, Jan 23 - Sun, Jan 25
Frontier Logo
10:30 am - 7:47 pmSNA-STL
7h 17m1 stop
Frontier Logo
10:10 pm - 7:21 pmSTL-SNA
23h 11m1 stop
$238Frontier
Find Deal
Fri, Dec 19 - Sun, Dec 21
Multiple Airlines Logo
8:19 pm - 12:12 pmSNA-STL
13h 53m1 stop
Multiple Airlines Logo
7:43 pm - 10:44 amSTL-SNA
17h 01m2 stops
$242Multiple Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15

Frontier flights from Santa Ana, California to St. Louis

Our best Frontier deals on Santa Ana, California to St. Louis flight tickets
Frontier
Dec 11
SNA11:15 amSanta Ana J. Wayne/Orange Cnty
20h 59m
1 stop
STL10:14 amLambert-St Louis
Dec 15
STL7:43 pmLambert-St Louis
18h 59m
1 stop
SNA12:42 pmSanta Ana J. Wayne/Orange Cnty
$182
Find similar
Frontier
Jan 23
SNA12:17 pmSanta Ana J. Wayne/Orange Cnty
24h 29m
1 stop
STL2:46 pmLambert-St Louis
Jan 25
STL1:03 pmLambert-St Louis
22h 09m
1 stop
SNA9:12 amSanta Ana J. Wayne/Orange Cnty
$186
Find similar
Frontier
Jan 26
SNA10:07 amSanta Ana J. Wayne/Orange Cnty
8h 43m
2 stops
STL8:50 pmLambert-St Louis
Jan 28
STL3:46 pmLambert-St Louis
21h 12m
1 stop
SNA10:58 amSanta Ana J. Wayne/Orange Cnty
$199
Find similar

Delta flights from Santa Ana, California to St. Louis

Our best Delta deals on Santa Ana, California to St. Louis flight tickets
Delta
Jan 26
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
12h 08m
2 stops
STL9:38 pmLambert-St Louis
Jan 28
STL6:40 amLambert-St Louis
11h 54m
2 stops
SNA4:34 pmSanta Ana J. Wayne/Orange Cnty
$316
Find similar
Delta
Jan 23
SNA11:15 amSanta Ana J. Wayne/Orange Cnty
10h 08m
2 stops
STL11:23 pmLambert-St Louis
Jan 25
STL6:40 amLambert-St Louis
11h 54m
2 stops
SNA4:34 pmSanta Ana J. Wayne/Orange Cnty
$331
Find similar
Delta
Jan 8
SNA1:35 pmSanta Ana J. Wayne/Orange Cnty
6h 00m
1 stop
STL9:35 pmLambert-St Louis
Jan 11
STL3:45 pmLambert-St Louis
8h 30m
1 stop
SNA10:15 pmSanta Ana J. Wayne/Orange Cnty
$384
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 25, 2025.
Use the filters below to find and compare flights from Santa Ana, California to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

7:45 am-8:50 pm

1 stop11h 05m

Lambert-St Louis

Wed 1/28

3:46 pm-10:58 am

1 stop21h 12m

$164

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

11:15 am-10:14 am

1 stop20h 59m

Lambert-St Louis

Mon 12/15

7:43 pm-12:42 pm

1 stop18h 59m

$182

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 1/23

12:17 pm-2:46 pm

1 stop24h 29m

Lambert-St Louis

Sun 1/25

1:03 pm-9:12 am

1 stop22h 09m

$186

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

10:07 am-8:50 pm

2 stops8h 43m

Lambert-St Louis

Wed 1/28

3:46 pm-10:58 am

1 stop21h 12m

$199

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 1/23

7:45 am-8:48 pm

1 stop11h 03m

Lambert-St Louis

Sun 1/25

9:27 pm-12:25 pm

1 stop16h 58m

$202

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 12/5

1:35 pm-10:14 am

1 stop18h 39m

Lambert-St Louis

Mon 12/8

1:16 pm-5:39 pm

1 stop6h 23m

$207

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

8:19 pm-12:12 pm

1 stop13h 53m

Lambert-St Louis

Mon 12/15

1:16 pm-10:44 am

1 stop23h 28m

$214

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 1/23

7:45 am-8:48 pm

1 stop11h 03m

Lambert-St Louis

Sun 1/25

9:27 pm-2:11 pm

2 stops18h 44m

$237

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 12/19

10:30 am-7:47 pm

1 stop7h 17m

Lambert-St Louis

Sun 12/21

10:10 pm-7:21 pm

1 stop23h 11m

$238

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

8:19 pm-12:12 pm

1 stop13h 53m

Lambert-St Louis

Mon 12/15

7:43 pm-10:44 am

2 stops17h 01m

$242

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana, California to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Santa Ana, California to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $329. The month of August is another great option to travel to St. Louis, with average flight prices from Santa Ana, California averaging around $374.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $391. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $431. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana, California in the evening is the least expensive time of day to depart. momondo users have found prices as low as $375 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $426 per ticket.

How have Santa Ana, California to St. Louis flight prices changed over time?

As of November 2025, prices for Santa Ana, California to St. Louis flights are approximately 48% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to St. Louis

Fastest flight time

7h 09m

Direct flights

None
The fastest flight from Santa Ana, California to St. Louis takes 7h 09m
There are no direct flights from Santa Ana, California to St. Louis. There are no popular flight routes from Santa Ana, California to St. Louis.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 26m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana, California to St. Louis?

Best airlines flying from Santa Ana, California to St. Louis

Compare and see reviews for airlines that fly from Santa Ana, California to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.8
3,099 reviews
Search Frontier flights
DeltaPriceFrom $248Free CancellationRating
7.9
7,999 reviews
Search Delta flights
American AirlinesPriceFrom $278Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights
SouthwestPriceFrom $311Free CancellationRating
8.0
4,254 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,046 reviews
Search United Airlines flights

  • Southwest Flights From Santa Ana, California to St. Louis

    Southwest flies from Santa Ana, California to St. Louis around 5 times per week, with 4,254 momondo users rating the airline 8.0/10. The cheapest Southwest deal from Santa Ana, California to St. Louis in the last 72 hours was $311 (round-trip), much lower than the average airfare cost of $461 for Southwest flights on this route.

  • United Airlines Flights From Santa Ana, California to St. Louis

    United Airlines is also a popular choice for this route. United Airlines flight deals for Santa Ana, California to St. Louis start from as low as $311 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $450. United Airlines operates 5 flights to St. Louis from Santa Ana, California in an average week. Users have rated it 7.4/10 across 9,046 reviews.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Wentzville
Fenton
Collinsville
St. Peters
Alton
Farmington
Festus
Glencoe
Edwardsville
Clayton
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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