Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santa Ana to St. Louis from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to St. Louis departing on 10/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santa Ana to St. Louis

Cheap round-trip flights

Frontier Logo
2:35 pm - 10:14 pmSNA-STL
5h 39m1 stop
Frontier Logo
12:38 pm - 7:08 pmSTL-SNA
8h 30m1 stop
$144Frontier
Find Deal
Fri, Oct 24 - Mon, Oct 27
Frontier Logo
12:58 pm - 9:06 amSNA-STL
18h 08m1 stop
Frontier Logo
2:38 pm - 12:15 pmSTL-SNA
23h 37m1 stop
$156Frontier
Find Deal
Sat, Sep 27 - Sun, Sep 28
Multiple Airlines Logo
5:46 pm - 1:57 pmSNA-STL
18h 11m1 stop
Multiple Airlines Logo
2:42 pm - 8:59 pmSTL-SNA
8h 17m1 stop
$158Multiple Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Frontier Logo
2:35 pm - 10:14 pmSNA-STL
5h 39m1 stop
Frontier Logo
12:38 pm - 7:08 pmSTL-SNA
8h 30m1 stop
$188Frontier
Find Deal
Fri, Oct 10 - Mon, Oct 13
Delta Logo
9:42 am - 6:40 pmSNA-STL
6h 58m1 stop
Delta Logo
3:59 pm - 10:28 pmSTL-SNA
8h 29m1 stop
$333Delta
Find Deal
Tue, Oct 14 - Tue, Oct 21
Southwest Logo
3:30 pm - 11:10 pmSNA-STL
5h 40m1 stop
Southwest Logo
1:45 pm - 8:45 pmSTL-SNA
9h 00m2 stops
$338Southwest
Find Deal
Tue, Oct 14 - Sat, Oct 18
Delta Logo
6:59 pm - 8:51 amSNA-STL
11h 52m2 stops
Delta Logo
5:15 pm - 10:28 pmSTL-SNA
7h 13m1 stop
$348Delta
Find Deal
Fri, Oct 24 - Mon, Oct 27
American Airlines Logo
11:28 am - 8:53 pmSNA-STL
7h 25m1 stop
American Airlines Logo
5:17 am - 9:53 amSTL-SNA
6h 36m1 stop
$354American Airlines
Find Deal
Tue, Oct 21 - Thu, Nov 20
Southwest Logo
7:15 am - 5:25 pmSNA-STL
8h 10m2 stops
Southwest Logo
1:45 pm - 8:45 pmSTL-SNA
9h 00m2 stops
$364Southwest
Find Deal
Tue, Oct 14 - Sat, Oct 18
United Airlines Logo
11:32 am - 10:35 pmSNA-STL
9h 03m2 stops
United Airlines Logo
5:15 am - 9:17 amSTL-SNA
6h 02m1 stop
$365United Airlines
Find Deal
Tue, Oct 7 - Thu, Oct 9

Frontier flights from Santa Ana to St. Louis

Our best Frontier deals on Santa Ana to St. Louis flight tickets
Frontier
Oct 24
SNA2:35 pmSanta Ana J. Wayne/Orange Cnty
5h 39m
1 stop
STL10:14 pmLambert-St Louis
Oct 27
STL12:38 pmLambert-St Louis
8h 30m
1 stop
SNA7:08 pmSanta Ana J. Wayne/Orange Cnty
$144
Find similar
Frontier
Sep 27
SNA12:58 pmSanta Ana J. Wayne/Orange Cnty
18h 08m
1 stop
STL9:06 amLambert-St Louis
Sep 28
STL2:38 pmLambert-St Louis
23h 37m
1 stop
SNA12:15 pmSanta Ana J. Wayne/Orange Cnty
$156
Find similar
Frontier
Oct 10
SNA2:35 pmSanta Ana J. Wayne/Orange Cnty
5h 39m
1 stop
STL10:14 pmLambert-St Louis
Oct 13
STL12:38 pmLambert-St Louis
8h 30m
1 stop
SNA7:08 pmSanta Ana J. Wayne/Orange Cnty
$188
Find similar

Delta flights from Santa Ana to St. Louis

Our best Delta deals on Santa Ana to St. Louis flight tickets
Delta
Oct 14
SNA9:42 amSanta Ana J. Wayne/Orange Cnty
6h 58m
1 stop
STL6:40 pmLambert-St Louis
Oct 21
STL3:59 pmLambert-St Louis
8h 29m
1 stop
SNA10:28 pmSanta Ana J. Wayne/Orange Cnty
$333
Find similar
Delta
Oct 24
SNA6:59 pmSanta Ana J. Wayne/Orange Cnty
11h 52m
2 stops
STL8:51 amLambert-St Louis
Oct 27
STL5:15 pmLambert-St Louis
7h 13m
1 stop
SNA10:28 pmSanta Ana J. Wayne/Orange Cnty
$348
Find similar
Delta
Nov 24
SNA5:20 pmSanta Ana J. Wayne/Orange Cnty
5h 26m
1 stop
STL12:46 amLambert-St Louis
Dec 2
STL5:34 pmLambert-St Louis
22h 41m
2 stops
SNA2:15 pmSanta Ana J. Wayne/Orange Cnty
$353
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

2:35 pm-10:14 pm

1 stop5h 39m

Lambert-St Louis

Mon 10/27

12:38 pm-7:08 pm

1 stop8h 30m

$144

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 9/27

12:58 pm-9:06 am

1 stop18h 08m

Lambert-St Louis

Sun 9/28

2:38 pm-12:15 pm

1 stop23h 37m

$156

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 11/13

5:46 pm-1:57 pm

1 stop18h 11m

Lambert-St Louis

Mon 11/17

2:42 pm-8:59 pm

1 stop8h 17m

$158

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 10/10

2:35 pm-10:14 pm

1 stop5h 39m

Lambert-St Louis

Mon 10/13

12:38 pm-7:08 pm

1 stop8h 30m

$188

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 10/14

9:42 am-6:40 pm

1 stop6h 58m

Lambert-St Louis

Tue 10/21

3:59 pm-10:28 pm

1 stop8h 29m

$333

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 10/14

3:30 pm-11:10 pm

1 stop5h 40m

Lambert-St Louis

Sat 10/18

1:45 pm-8:45 pm

2 stops9h 00m

$338

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

6:59 pm-8:51 am

2 stops11h 52m

Lambert-St Louis

Mon 10/27

5:15 pm-10:28 pm

1 stop7h 13m

$348

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 10/21

11:28 am-8:53 pm

1 stop7h 25m

Lambert-St Louis

Thu 11/20

5:17 am-9:53 am

1 stop6h 36m

$354

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 10/14

7:15 am-5:25 pm

2 stops8h 10m

Lambert-St Louis

Sat 10/18

1:45 pm-8:45 pm

2 stops9h 00m

$364

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 10/7

11:32 am-10:35 pm

2 stops9h 03m

Lambert-St Louis

Thu 10/9

5:15 am-9:17 am

1 stop6h 02m

$365

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, August is the cheapest month to fly from Santa Ana to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $374. The month of October is another great option to travel to St. Louis, with average flight prices from Santa Ana averaging around $376.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $398. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $451. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana in the evening is the least expensive time of day to depart. momondo users have found prices as low as $389 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $428 per ticket.

How have Santa Ana to St. Louis flight prices changed over time?

As of September 2025, prices for Santa Ana to St. Louis flights are approximately 1% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to St. Louis

Direct flights

None
There are no direct flights from Santa Ana to St. Louis. There are no popular flight routes from Santa Ana to St. Louis.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 26m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana to St. Louis?

Best airlines flying from Santa Ana to St. Louis

Compare and see reviews for airlines that fly from Santa Ana to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $138Free CancellationRating
5.8
3,173 reviews
Search Frontier flights
DeltaPriceFrom $248Free CancellationRating
7.9
7,961 reviews
Search Delta flights
SouthwestPriceFrom $311Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
American AirlinesPriceFrom $326Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • United Airlines Flights From Santa Ana to St. Louis

    United Airlines flies from Santa Ana to St. Louis around 6 times per week, with 8,926 momondo users rating the airline 7.4/10. The cheapest United Airlines deal from Santa Ana to St. Louis in the last 72 hours was $311 (round-trip), much lower than the average airfare cost of $451 for United Airlines flights on this route.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Fenton
Collinsville
Wentzville
Alton
St. Peters
Farmington
Festus
Glencoe
Clayton
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 10/17
Fri 10/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States