Cheap flights from Santa Ana, California to St. Louis from $146
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to St. Louis departing on 10/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 11/25
2:12 pm-4:20 pm
1 stop24h 08m
Lambert-St Louis
Fri 11/27
3:04 pm-5:24 pm
1 stop28h 20m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 11/5
6:51 pm-8:54 am
1 stop12h 03m
Lambert-St Louis
Mon 11/9
1:28 pm-7:11 pm
1 stop7h 43m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Mon 11/2
4:35 pm-12:15 am
1 stop5h 40m
Lambert-St Louis
Tue 11/10
5:55 am-10:50 am
1 stop6h 55m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sat 11/7
3:23 pm-11:59 pm
1 stop6h 36m
Lambert-St Louis
Sat 11/14
2:54 pm-7:10 pm
1 stop6h 16m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 11/18
8:00 am-6:16 pm
1 stop8h 16m
Lambert-St Louis
Thu 11/19
6:00 am-11:10 am
1 stop7h 10m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sat 11/7
7:15 am-9:09 pm
2 stops11h 54m
Lambert-St Louis
Sat 11/14
11:34 am-10:30 pm
2 stops12h 56m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 11/18
8:50 am-5:25 pm
2 stops6h 35m
Lambert-St Louis
Thu 11/19
5:05 am-8:55 am
1 stop5h 50m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Sat 11/7
6:45 am-3:43 pm
1 stop6h 58m
Lambert-St Louis
Sat 11/14
8:30 am-2:59 pm
2 stops8h 29m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 3/3
2:03 pm-11:19 pm
1 stop7h 16m
Lambert-St Louis
Thu 3/4
8:30 am-1:49 pm
1 stop7h 19m
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 10/27
4:55 pm-12:44 am
1 stop5h 49m
Lambert-St Louis
Thu 10/29
7:45 am-11:58 am
1 stop6h 13m
See travel insights to St. Louis from
How to get the cheapest flight ticket from Santa Ana, California to St. Louis
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Santa Ana, California and St. Louis?
Prices are currently low for flights on this route.
Typical prices usually range from $328 to $456.The lowest price recently found on this route was $266.
What is the cheapest month to fly to St. Louis?
In general, October is the cheapest month to fly from Santa Ana, California to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $398. The month of February is another great option to travel to St. Louis, with average flight prices from Santa Ana, California averaging around $416.
What is the cheapest day to depart on your flight to St. Louis?
The cheapest day to depart on your flight to St. Louis is on a Tuesday when prices can be found for as low as $425. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $596. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.
What is the cheapest time of day to depart on your flight to St. Louis?
Flying to St. Louis from Santa Ana, California in the evening is the least expensive time of day to depart. momondo users have found prices as low as $397 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $578 per ticket.
How have Santa Ana, California to St. Louis flight prices changed over time?
As of October 2026, prices for Santa Ana, California to St. Louis flights are approximately 127% more expensive when compared to flights at the same time last year.
What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis?
Frontier, Southwest, and Delta are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis
What airlines fly to St. Louis?
Southwest, American Airlines and Frontier are the top three most popular airlines that fly to St. Louis from Santa Ana, California according to our data. Southwest is the first choice among our users, with 55% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 7 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.
When to book flights from Santa Ana, California to St. Louis
Cheap Santa Ana, California to St. Louis (SNA to STL) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to St. Louis
Frequently asked questions about flying from Santa Ana, California to St. Louis
How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?
The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 4h 55m.
When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?
As of October 2026, there are 4 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.
What documentation or ID do you need to fly to Lambert-St Louis Airport?
The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Santa Ana, California to St. Louis?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Santa Ana, California to St. Louis is Southwest (49% of total bookings). The next most popular airlines are American Airlines (28%), United Airlines (16%), and Delta (6%).
Best airlines flying from Santa Ana, California to St. Louis
Compare and see reviews for airlines that fly from Santa Ana, California to St. Louis with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $276 | Free Cancellation | Rating 7.8 8,641 reviews | |||
| PriceFrom $328 | Free Cancellation | Rating 7.0 12,145 reviews | |||
| PriceFrom $356 | Free Cancellation | Rating 7.4 10,319 reviews | |||
| PriceFrom $361 | Free Cancellation | Rating 7.9 4,221 reviews |
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Why should I use momondo to find a flight deal from Santa Ana to St. Louis?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.
Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?
All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.
How can momondo help me find flights from Santa Ana to St. Louis?
momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.
I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?
Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.