Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santa Ana, California to St. Louis from $70

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to St. Louis departing on 2/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santa Ana, California to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
1:20 pm - 9:26 pm
SNA
-
STL
6h 06m
1 stop
Multiple Airlines Logo
10:11 pm - 12:25 pm
STL
-
SNA
16h 14m
1 stop
$138Multiple Airlines
Thu, Feb 19 - Mon, Feb 23
Multiple Airlines Logo
4:02 pm - 5:46 pm
SNA
-
STL
23h 44m
1 stop
Multiple Airlines Logo
10:11 pm - 3:42 pm
STL
-
SNA
19h 31m
1 stop
$140Multiple Airlines
Fri, Feb 27 - Mon, Mar 2
Multiple Airlines Logo
6:45 am - 9:26 pm
SNA
-
STL
12h 41m
1 stop
Multiple Airlines Logo
10:11 pm - 3:42 pm
STL
-
SNA
19h 31m
1 stop
$141Multiple Airlines
Fri, Feb 20 - Mon, Feb 23
Multiple Airlines Logo
1:20 pm - 9:26 pm
SNA
-
STL
6h 06m
1 stop
Multiple Airlines Logo
10:11 pm - 8:13 am
STL
-
SNA
12h 02m
1 stop
$153Multiple Airlines
Thu, Feb 26 - Sun, Mar 1
Frontier Logo
12:36 pm - 8:02 pm
SNA
-
STL
5h 26m
1 stop
Frontier Logo
4:51 pm - 8:13 am
STL
-
SNA
17h 22m
2 stops
$154Frontier
Mon, Feb 23 - Wed, Feb 25
Multiple Airlines Logo
1:20 pm - 9:26 pm
SNA
-
STL
6h 06m
1 stop
Multiple Airlines Logo
10:11 pm - 12:25 pm
STL
-
SNA
16h 14m
1 stop
$155Multiple Airlines
Thu, Feb 26 - Mon, Mar 2
Multiple Airlines Logo
8:58 am - 9:26 pm
SNA
-
STL
10h 28m
1 stop
Multiple Airlines Logo
10:11 pm - 12:25 pm
STL
-
SNA
16h 14m
1 stop
$156Multiple Airlines
Thu, Feb 26 - Mon, Mar 2
Multiple Airlines Logo
4:37 pm - 9:26 pm
SNA
-
STL
26h 49m
1 stop
Multiple Airlines Logo
10:11 pm - 3:42 pm
STL
-
SNA
19h 31m
1 stop
$158Multiple Airlines
Wed, Feb 25 - Mon, Mar 2
Multiple Airlines Logo
6:45 am - 5:46 pm
SNA
-
STL
9h 01m
1 stop
Multiple Airlines Logo
10:11 pm - 11:40 am
STL
-
SNA
15h 29m
2 stops
$171Multiple Airlines
Sat, Feb 14 - Fri, Feb 20
Multiple Airlines Logo
5:10 pm - 1:56 pm
SNA
-
STL
18h 46m
2 stops
Multiple Airlines Logo
10:11 pm - 12:25 pm
STL
-
SNA
16h 14m
1 stop
$176Multiple Airlines
Fri, Feb 20 - Mon, Feb 23

Frontier flights from Santa Ana, California to St. Louis

Our best Frontier deals on Santa Ana, California to St. Louis flight tickets
Frontier
Feb 26
SNA8:58 amSanta Ana J. Wayne/Orange Cnty
10h 28m
1 stop
STL9:26 pmLambert-St Louis
Mar 1
STL10:11 pmLambert-St Louis
12h 02m
1 stop
SNA8:13 amSanta Ana J. Wayne/Orange Cnty
$155
Frontier
Feb 26
SNA8:58 amSanta Ana J. Wayne/Orange Cnty
10h 28m
1 stop
STL9:26 pmLambert-St Louis
Mar 3
STL3:49 pmLambert-St Louis
52h 51m
2 stops
SNA6:40 pmSanta Ana J. Wayne/Orange Cnty
$212
Frontier
Apr 10
SNA5:56 pmSanta Ana J. Wayne/Orange Cnty
16h 25m
1 stop
STL12:21 pmLambert-St Louis
Apr 13
STL12:22 pmLambert-St Louis
9h 13m
1 stop
SNA7:35 pmSanta Ana J. Wayne/Orange Cnty
$230

Southwest flights from Santa Ana, California to St. Louis

Our best Southwest deals on Santa Ana, California to St. Louis flight tickets
Southwest
Feb 26
SNA4:05 pmSanta Ana J. Wayne/Orange Cnty
6h 45m
2 stops
STL12:50 amLambert-St Louis
Mar 3
STL2:15 pmLambert-St Louis
7h 35m
2 stops
SNA7:50 pmSanta Ana J. Wayne/Orange Cnty
$326
Southwest
Feb 23
SNA3:55 pmSanta Ana J. Wayne/Orange Cnty
5h 50m
1 stop
STL11:45 pmLambert-St Louis
Feb 25
STL2:15 pmLambert-St Louis
7h 35m
2 stops
SNA7:50 pmSanta Ana J. Wayne/Orange Cnty
$340
Southwest
Mar 29
SNA5:50 pmSanta Ana J. Wayne/Orange Cnty
5h 30m
1 stop
STL1:20 amLambert-St Louis
Apr 1
STL6:20 amLambert-St Louis
7h 50m
2 stops
SNA12:10 pmSanta Ana J. Wayne/Orange Cnty
$353

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 24, 2026.
Use the filters below to find and compare flights from Santa Ana, California to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 2/19

1:20 pm-9:26 pm

1 stop6h 06m

Lambert-St Louis

Mon 2/23

10:11 pm-12:25 pm

1 stop16h 14m

$138

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 2/27

4:02 pm-5:46 pm

1 stop23h 44m

Lambert-St Louis

Mon 3/2

10:11 pm-3:42 pm

1 stop19h 31m

$140

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 2/20

6:45 am-9:26 pm

1 stop12h 41m

Lambert-St Louis

Mon 2/23

10:11 pm-3:42 pm

1 stop19h 31m

$141

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

1:20 pm-9:26 pm

1 stop6h 06m

Lambert-St Louis

Sun 3/1

10:11 pm-8:13 am

1 stop12h 02m

$153

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 2/23

12:36 pm-8:02 pm

1 stop5h 26m

Lambert-St Louis

Wed 2/25

4:51 pm-8:13 am

2 stops17h 22m

$154

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

1:20 pm-9:26 pm

1 stop6h 06m

Lambert-St Louis

Mon 3/2

10:11 pm-12:25 pm

1 stop16h 14m

$155

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

8:58 am-9:26 pm

1 stop10h 28m

Lambert-St Louis

Mon 3/2

10:11 pm-12:25 pm

1 stop16h 14m

$156

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 2/25

4:37 pm-9:26 pm

1 stop26h 49m

Lambert-St Louis

Mon 3/2

10:11 pm-3:42 pm

1 stop19h 31m

$158

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

6:45 am-5:46 pm

1 stop9h 01m

Lambert-St Louis

Fri 2/20

10:11 pm-11:40 am

2 stops15h 29m

$171

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 2/20

5:10 pm-1:56 pm

2 stops18h 46m

Lambert-St Louis

Mon 2/23

10:11 pm-12:25 pm

1 stop16h 14m

$176

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to St. Louis from

How to get the cheapest flight ticket from Santa Ana, California to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, October is the cheapest month to fly from Santa Ana, California to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $329. The month of August is another great option to travel to St. Louis, with average flight prices from Santa Ana, California averaging around $374.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $388. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $428. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Santa Ana, California in the evening is the least expensive time of day to depart. momondo users have found prices as low as $351 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $407 per ticket.

How have Santa Ana, California to St. Louis flight prices changed over time?

As of January 2026, prices for Santa Ana, California to St. Louis flights are approximately 60% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to St. Louis (SNA to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to St. Louis

Fastest flight time

5h 33m

Direct flights

None
The fastest flight from Santa Ana, California to St. Louis takes 5h 33m
There are no direct flights from Santa Ana, California to St. Louis. There are no popular flight routes from Santa Ana, California to St. Louis.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis is 1572.0 mi. By plane, this route typically takes 5h 33m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana, California to St. Louis?

Best airlines flying from Santa Ana, California to St. Louis

Compare and see reviews for airlines that fly from Santa Ana, California to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.7
3,058 reviews
Search Frontier flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,110 reviews
Search Delta flights
American AirlinesPriceFrom $278Free CancellationRating
7.2
11,192 reviews
Search American Airlines flights
SouthwestPriceFrom $306Free CancellationRating
8.0
4,268 reviews
Search Southwest flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,194 reviews
Search United Airlines flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
Florissant
O'Fallon
Fenton
Collinsville
St. Peters
Wentzville
Alton
Farmington
Clayton
Eureka
Edwardsville
Festus
Glencoe
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to St. Louis for you.

Can I find flights from Santa Ana to St. Louis with flexible booking policies on momondo?

All flight searches from Santa Ana to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to St. Louis right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to St. Louis flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 2/23
Mon 3/2
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States