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Cheap flights from Santa Ana, California to Indianapolis from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Indianapolis departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:30 am - 1:12 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
26h 42m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
2:23 pm - 5:15 pmIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
29h 52m1 stop Las Vegas Harry Reid Intl
$273Multiple Airlines
Wed, Sep 9 - Sun, Sep 13
Multiple Airlines Logo
7:30 am - 1:12 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
26h 42m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
7:48 pm - 10:00 amIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
17h 12m2 stops Atlanta Hartsfield-Jackson Dallas/Fort Worth
$275Multiple Airlines
Wed, Sep 9 - Wed, Sep 16
Multiple Airlines Logo
7:30 am - 1:12 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
26h 42m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
7:48 pm - 10:00 amIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
17h 12m2 stops Atlanta Hartsfield-Jackson Dallas/Fort Worth
$282Multiple Airlines
Wed, Sep 9 - Wed, Sep 16
Southwest Logo
8:50 am - 11:25 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
11h 35m1 stop Las Vegas Harry Reid Intl
Southwest Logo
6:00 pm - 8:55 pmIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
5h 55m1 stop Denver Intl
$318Southwest
Sat, Sep 19 - Sat, Sep 26
Southwest Logo
12:00 pm - 11:25 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
8h 25m2 stops Sacramento Intl Las Vegas Harry Reid Intl
Southwest Logo
11:35 am - 3:45 pmIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
7h 10m1 stop Austin Bergstrom
$318Southwest
Sat, Sep 19 - Sat, Sep 26
United Airlines Logo
8:10 am - 7:02 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
7h 52m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
7:20 am - 12:06 pmIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
7h 46m1 stop San Francisco
$356United Airlines
Tue, Sep 1 - Wed, Sep 9
American Airlines Logo
9:07 am - 7:26 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
7h 19m1 stop Dallas/Fort Worth
American Airlines Logo
6:06 am - 8:52 amIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
5h 46m1 stop Phoenix Sky Harbor Intl
$369American Airlines
Thu, Sep 3 - Tue, Sep 8
American Airlines Logo
12:14 pm - 10:19 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
7h 05m1 stop Dallas/Fort Worth
American Airlines Logo
8:14 am - 12:31 pmIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
7h 17m1 stop Phoenix Sky Harbor Intl
$369American Airlines
Tue, Sep 29 - Wed, Sep 30
United Airlines Logo
2:22 pm - 11:47 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
6h 25m1 stop Chicago O'Hare Intl
United Airlines Logo
3:44 pm - 10:00 pmIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
9h 16m1 stop Denver Intl
$369United Airlines
Thu, Nov 12 - Mon, Nov 16
Southwest Logo
9:15 am - 8:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-IND Indianapolis
8h 40m2 stops Oakland Las Vegas Harry Reid Intl
Southwest Logo
11:00 am - 5:30 pmIND  Indianapolis-SNA Santa Ana J. Wayne/Orange Cnty
9h 30m2 stops Austin Bergstrom Phoenix Sky Harbor Intl
$379Southwest
Tue, Sep 1 - Wed, Sep 9

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Frontier flights from Santa Ana, California to Indianapolis

Our best Frontier deals on Santa Ana, California to Indianapolis flight tickets
Frontier
Sep 6
SNA9:39 amSanta Ana J. Wayne/Orange Cnty
7h 25m
1 stop
IND8:04 pmIndianapolis
Sep 16
IND7:48 pmIndianapolis
17h 12m
2 stops
SNA10:00 amSanta Ana J. Wayne/Orange Cnty
$310
Frontier
Sep 11
SNA11:50 amSanta Ana J. Wayne/Orange Cnty
24h 27m
1 stop
IND3:17 pmIndianapolis
Sep 13
IND8:56 pmIndianapolis
17h 09m
1 stop
SNA11:05 amSanta Ana J. Wayne/Orange Cnty
$319
Frontier
Sep 6
SNA9:39 amSanta Ana J. Wayne/Orange Cnty
7h 25m
1 stop
IND8:04 pmIndianapolis
Sep 16
IND4:12 pmIndianapolis
21h 53m
1 stop
SNA11:05 amSanta Ana J. Wayne/Orange Cnty
$325

Southwest flights from Santa Ana, California to Indianapolis

Our best Southwest deals on Santa Ana, California to Indianapolis flight tickets
Southwest
Sep 19
SNA12:00 pmSanta Ana J. Wayne/Orange Cnty
8h 25m
2 stops
IND11:25 pmIndianapolis
Sep 26
IND11:35 amIndianapolis
7h 10m
1 stop
SNA3:45 pmSanta Ana J. Wayne/Orange Cnty
$318
Southwest
Sep 1
SNA9:15 amSanta Ana J. Wayne/Orange Cnty
8h 40m
2 stops
IND8:55 pmIndianapolis
Sep 9
IND11:00 amIndianapolis
9h 30m
2 stops
SNA5:30 pmSanta Ana J. Wayne/Orange Cnty
$379
Southwest
Sep 4
SNA2:05 pmSanta Ana J. Wayne/Orange Cnty
8h 15m
1 stop
IND1:20 amIndianapolis
Sep 11
IND1:30 pmIndianapolis
8h 30m
1 stop
SNA7:00 pmSanta Ana J. Wayne/Orange Cnty
$381

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

7:30 am-1:12 pm

1 stop26h 42m

Indianapolis

Sun 9/13

2:23 pm-5:15 pm

1 stop29h 52m

$273

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

7:30 am-1:12 pm

1 stop26h 42m

Indianapolis

Wed 9/16

7:48 pm-10:00 am

2 stops17h 12m

$275

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

7:30 am-1:12 pm

1 stop26h 42m

Indianapolis

Wed 9/16

7:48 pm-10:00 am

2 stops17h 12m

$282

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Sat 9/19

8:50 am-11:25 pm

1 stop11h 35m

Indianapolis

Sat 9/26

6:00 pm-8:55 pm

1 stop5h 55m

$318

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Sat 9/19

12:00 pm-11:25 pm

2 stops8h 25m

Indianapolis

Sat 9/26

11:35 am-3:45 pm

1 stop7h 10m

$318

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Tue 9/1

8:10 am-7:02 pm

1 stop7h 52m

Indianapolis

Wed 9/9

7:20 am-12:06 pm

1 stop7h 46m

$356
Quickest round-trip

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 9/3

9:07 am-7:26 pm

1 stop7h 19m

Indianapolis

Tue 9/8

6:06 am-8:52 am

1 stop5h 46m

$369

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Tue 9/29

12:14 pm-10:19 pm

1 stop7h 05m

Indianapolis

Wed 9/30

8:14 am-12:31 pm

1 stop7h 17m

$369

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 11/12

2:22 pm-11:47 pm

1 stop6h 25m

Indianapolis

Mon 11/16

3:44 pm-10:00 pm

1 stop9h 16m

$369

Santa AnaIndianapolis

SNA Santa Ana J. Wayne/Orange Cnty - IND Indianapolis

SNAIND

Santa Ana J. Wayne/Orange Cnty

Tue 9/1

9:15 am-8:55 pm

2 stops8h 40m

Indianapolis

Wed 9/9

11:00 am-5:30 pm

2 stops9h 30m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Santa Ana, California to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and Indianapolis?

Prices are currently low for flights on this route.

Typical prices usually range from $374 to $512.
The lowest price recently found on this route was $273.

What is the cheapest month to fly to Indianapolis?

In general, February is the cheapest month to fly from Santa Ana, California to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you are unable to visit Indianapolis during the month of February, then departing from Santa Ana, California during the month September is also very affordable. Most momondo users find prices during this month for around $426.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Saturday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $409. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Monday is $554.

What is the cheapest time of day to depart on your flight to Indianapolis?

Flying to Indianapolis from Santa Ana, California at noon is the least expensive time of day to depart. momondo users have found prices as low as $329 when looking at flights departing at noon. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $482 on average. Flights to Indianapolis from Santa Ana, California in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight from Santa Ana, California to Indianapolis?

You are more likely to see cheaper flights to Indianapolis from Santa Ana, California when booking weeks ahead of your departure date. In general, you can expect to find flights to Indianapolis for around $506 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Indianapolis from Santa Ana, California for as low as $296 on momondo.

How have Santa Ana, California to Indianapolis flight prices changed over time?

As of August 2026, prices for Santa Ana, California to Indianapolis flights are approximately 42% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Indianapolis (SNA to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Indianapolis

Fastest flight time

6h 15m

Direct flights

None
The fastest flight from Santa Ana, California to Indianapolis takes 6h 15m
There are no direct flights from Santa Ana, California to Indianapolis. There are no popular flight routes from Santa Ana, California to Indianapolis.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Indianapolis

  • How far is Santa Ana J. Wayne/Orange Cnty to Indianapolis by plane?

    Indianapolis is 1792.7 mi away from Santa Ana J. Wayne/Orange Cnty. Typically, this will take 6h 15m by plane in normal conditions.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Indianapolis Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Indianapolis Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Indianapolis Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Indianapolis?

Best airlines flying from Santa Ana, California to Indianapolis

Compare and see reviews for airlines that fly from Santa Ana, California to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $301Free CancellationRating
7.1
11,898 reviews
Search American Airlines flights
United AirlinesPriceFrom $326Free CancellationRating
7.4
10,099 reviews
Search United Airlines flights
SouthwestPriceFrom $350Free CancellationRating
8.0
4,218 reviews
Search Southwest flights

  • United Airlines Flights From Santa Ana, California to Indianapolis

    United Airlines flight deals from Santa Ana, California to Indianapolis start from $326 round-trip. Over the 3 United Airlines flights for this route in a normal week, average airfare is usually $507 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Greenwood
Anderson
Plainfield
Noblesville
Carmel
West Lafayette
Speedway
Fishers
Franklin
Westfield
Seymour
Shelbyville
Brownsburg
Crawfordsville
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Indianapolis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to Indianapolis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to Indianapolis with flexible booking policies on momondo?

All flight searches from Santa Ana to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to Indianapolis?

Once all potential Santa Ana to Indianapolis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Indianapolis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Indianapolis from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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