What is the cheapest airline that flies from San Francisco to South Carolina?

Breeze Airways, Southwest, and United Airlines are the most popular carriers operating from San Francisco to South Carolina

What airlines fly to South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to South Carolina from San Francisco according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from San Francisco to South Carolina on average per week?

The number of flights available between San Francisco and South Carolina is 31 per week as of March 2026. The most frequent departure day is Mon, with 16% of weekly flights leaving on this day.

When did momondo last update prices for flights from San Francisco Airport to South Carolina?

Prices for flights from San Francisco Airport to South Carolina were last updated today.

How many operators does momondo search for flights from San Francisco Airport to South Carolina?

There are 7 operators available for flights from San Francisco Airport to South Carolina as of March 2026.

How old do you have to be to fly from San Francisco Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$120 Cheap Flights from San Francisco to South Carolina in 2026

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Find the cheapest flights from San Francisco to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:12 pm - 12:24 am

SFO

CHS

8h 12m

1 stop

4:46 pm - 11:15 pm

CHS

SFO

9h 29m

1 stop

$213American Airlines

Tue, May 5 - Wed, May 20

11:59 pm - 10:48 am

SFO

CHS

7h 49m

1 stop

6:20 pm - 11:04 pm

CHS

SFO

7h 44m

1 stop

$255American Airlines

Sat, May 2 - Sat, May 9

5:40 am - 7:10 pm

SFO

CHS

10h 30m

2 stops

8:00 am - 12:35 pm

CHS

SFO

7h 35m

1 stop

$276Southwest

Sat, Apr 18 - Sat, Apr 25

5:25 am - 9:05 pm

SFO

CHS

12h 40m

1 stop

12:00 pm - 9:25 pm

CHS

SFO

12h 25m

2 stops

$282Southwest

Tue, Apr 28 - Tue, May 5

12:46 pm - 10:36 pm

SFO

CHS

6h 50m

1 stop

7:00 am - 12:01 pm

CHS

SFO

8h 01m

1 stop

$290Breeze Airways

Thu, Sep 10 - Sun, Sep 13

12:46 pm - 10:36 pm

SFO

CHS

6h 50m

1 stop

6:20 am - 11:51 am

CHS

SFO

8h 31m

1 stop

$295Breeze Airways

Tue, Sep 15 - Wed, Sep 23

6:00 am - 3:16 pm

SFO

CAE

6h 16m

1 stop

7:12 pm - 11:55 pm

CAE

SFO

7h 43m

1 stop

$378Delta

Wed, Apr 15 - Fri, Apr 17

10:50 pm - 9:46 am

SFO

GSP

7h 56m

1 stop

7:42 pm - 1:17 am

GSP

SFO

8h 35m

1 stop

$383United Airlines

Wed, Apr 15 - Tue, Apr 21

10:50 pm - 9:51 am

SFO

CAE

8h 01m

1 stop

10:50 am - 5:39 pm

CAE

SFO

9h 49m

1 stop

$397United Airlines

Sun, Apr 12 - Sat, Apr 18

2:00 pm - 11:49 pm

SFO

CAE

6h 49m

1 stop

5:35 am - 11:35 am

CAE

SFO

9h 00m

1 stop

$399Delta

Sat, Jul 11 - Wed, Jul 15

American Airlines flights from San Francisco to South Carolina

Our best American Airlines deals on San Francisco to South Carolina flight tickets

American Airlines

May 5

SFO1:12 pmSan Francisco

8h 12m

1 stop

CHS12:24 amCharleston

May 20

CHS4:46 pmCharleston

9h 29m

1 stop

SFO11:15 pmSan Francisco

$213

American Airlines

May 2

SFO11:59 pmSan Francisco

7h 49m

1 stop

CHS10:48 amCharleston

May 9

CHS6:20 pmCharleston

7h 44m

1 stop

SFO11:04 pmSan Francisco

$255

American Airlines

Apr 21

SFO12:06 pmSan Francisco

7h 35m

1 stop

CHS10:41 pmCharleston

May 5

CHS6:10 amCharleston

9h 22m

1 stop

SFO12:32 pmSan Francisco

$271

Frontier flights from San Francisco to South Carolina

Our best Frontier deals on San Francisco to South Carolina flight tickets

Frontier

May 28

SFO11:36 amSan Francisco

16h 49m

1 stop

CLT7:25 amCharlotte Douglas

May 31

CLT7:14 pmCharlotte Douglas

16h 35m

2 stops

SFO8:49 amSan Francisco

$392

Frontier

Apr 16

SFO2:47 pmSan Francisco

15h 31m

2 stops

CLT9:18 amCharlotte Douglas

Apr 20

CLT6:18 pmCharlotte Douglas

9h 09m

1 stop

SFO12:27 amSan Francisco

$393

Frontier

Aug 12

SFO6:00 amSan Francisco

12h 24m

1 stop

CLT9:24 pmCharlotte Douglas

Aug 15

CLT11:26 amCharlotte Douglas

8h 15m

1 stop

SFO4:41 pmSan Francisco

$395

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Tue 5/5

1:12 pm-12:24 am

1 stop8h 12m

Charleston

Wed 5/20

4:46 pm-11:15 pm

1 stop9h 29m

$213

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Sat 5/2

11:59 pm-10:48 am

1 stop7h 49m

Charleston

Sat 5/9

6:20 pm-11:04 pm

1 stop7h 44m

$255

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Sat 4/18

5:40 am-7:10 pm

2 stops10h 30m

Charleston

Sat 4/25

8:00 am-12:35 pm

1 stop7h 35m

$276

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Tue 4/28

5:25 am-9:05 pm

1 stop12h 40m

Charleston

Tue 5/5

12:00 pm-9:25 pm

2 stops12h 25m

$282

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Thu 9/10

12:46 pm-10:36 pm

1 stop6h 50m

Charleston

Sun 9/13

7:00 am-12:01 pm

1 stop8h 01m

$290

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Tue 9/15

12:46 pm-10:36 pm

1 stop6h 50m

Charleston

Wed 9/23

6:20 am-11:51 am

1 stop8h 31m

$295

Quickest round-trip

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Wed 4/15

6:00 am-3:16 pm

1 stop6h 16m

Columbia Metropolitan

Fri 4/17

7:12 pm-11:55 pm

1 stop7h 43m

$378

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 4/15

10:50 pm-9:46 am

1 stop7h 56m

Greenville

Tue 4/21

7:42 pm-1:17 am

1 stop8h 35m

$383

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Sun 4/12

10:50 pm-9:51 am

1 stop8h 01m

Columbia Metropolitan

Sat 4/18

10:50 am-5:39 pm

1 stop9h 49m

$397

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Sat 7/11

2:00 pm-11:49 pm

1 stop6h 49m

Columbia Metropolitan

Wed 7/15

5:35 am-11:35 am

1 stop9h 00m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from San Francisco is in August. Flight prices, which tend to average around $298, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from San Francisco during October instead. Flights to South Carolina in October, while not as cheap as those in August, still average around $313.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $387 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from San Francisco for as low as $282 on momondo.

Can stopping save me money on San Francisco to South Carolina flights?

You could potentially save up to 47% on your flight if you consider stops on a San Francisco to South Carolina flight.

Cheap San Francisco to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South Carolina

Fastest flight time	5h 07m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from San Francisco to South Carolina takes 5h 07m

Direct flights go from San Francisco to South Carolina every day.

There are 57 airports in South Carolina. From San Francisco there are direct flights to Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from San Francisco Airport to South Carolina?
Prices for flights from San Francisco Airport to South Carolina were last updated today.
How many operators does momondo search for flights from San Francisco Airport to South Carolina?
There are 7 operators available for flights from San Francisco Airport to South Carolina as of March 2026.
How old do you have to be to fly from San Francisco Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from San Francisco to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from San Francisco to South Carolina is Airbus A220-300 (100.00% of total bookings).

Best airlines flying from San Francisco to South Carolina

Compare and see reviews for airlines that fly from San Francisco to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $167	Free Cancellation	Rating 8.1 273 reviews	Search Breeze Airways flights
American Airlines	PriceFrom $223	Free Cancellation	Rating 7.1 11,486 reviews	Search American Airlines flights
JetBlue	PriceFrom $234	Free Cancellation	Rating 7.2 2,906 reviews	Search JetBlue flights
Delta	PriceFrom $256	Free Cancellation	Rating 7.9 8,315 reviews	Search Delta flights
United Airlines	PriceFrom $262	Free Cancellation	Rating 7.4 9,465 reviews	Search United Airlines flights
Southwest	PriceFrom $293	Free Cancellation	Rating 8.0 4,326 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Francisco to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from San Francisco to South Carolina with flexible booking policies on momondo?

All flight searches from San Francisco to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from San Francisco.

I’m not ready to book a flight from San Francisco to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.