What airlines fly to South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to South Carolina from San Francisco according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from San Francisco to South Carolina?

Breeze Airways, Southwest, and Delta are the most popular carriers operating from San Francisco to South Carolina

How many flights depart from San Francisco to South Carolina on average per week?

The number of flights available between San Francisco and South Carolina is 31 per week as of May 2026. The most frequent departure day is Wed, with 23% of weekly flights leaving on this day.

When did momondo last update prices for flights from San Francisco Airport to South Carolina?

Prices for flights from San Francisco Airport to South Carolina were last updated today.

How many operators does momondo search for flights from San Francisco Airport to South Carolina?

There are 7 operators available for flights from San Francisco Airport to South Carolina as of May 2026.

How old do you have to be to fly from San Francisco Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$118 Cheap Flights from San Francisco to South Carolina in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from San Francisco to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:22 pm - 10:49 pm

SFO

CHS

7h 27m

1 stop

6:10 am - 11:09 am

CHS

SFO

7h 59m

1 stop

$251Breeze Airways

Sat, Sep 5 - Fri, Sep 11

12:22 pm - 10:49 pm

SFO

CHS

7h 27m

1 stop

6:10 am - 11:09 am

CHS

SFO

7h 59m

1 stop

$252Breeze Airways

Sat, Sep 5 - Fri, Sep 11

5:15 am - 3:40 pm

SFO

CLT

7h 25m

1 stop

7:05 pm - 12:15 am

CLT

SFO

8h 10m

1 stop

$307Southwest

Wed, Jul 8 - Wed, Jul 15

7:40 am - 9:25 pm

SFO

CLT

10h 45m

2 stops

6:35 pm - 11:05 pm

CLT

SFO

7h 30m

1 stop

$312Southwest

Wed, Sep 9 - Wed, Sep 23

11:49 pm - 10:44 am

SFO

CAE

7h 55m

1 stop

6:03 pm - 10:48 pm

CAE

SFO

7h 45m

1 stop

$329American Airlines

Mon, Jul 6 - Wed, Jul 15

11:59 pm - 9:22 am

SFO

CAE

6h 23m

1 stop

6:01 pm - 10:49 pm

CAE

SFO

7h 48m

1 stop

$335Delta

Sat, Jul 11 - Wed, Jul 15

11:59 pm - 9:22 am

SFO

CAE

6h 23m

1 stop

3:51 pm - 10:49 pm

CAE

SFO

9h 58m

1 stop

$363Delta

Thu, Jul 16 - Mon, Jul 20

5:54 am - 5:32 pm

SFO

HHH

8h 38m

1 stop

6:13 pm - 10:48 pm

HHH

SFO

7h 35m

1 stop

$369American Airlines

Wed, Oct 21 - Wed, Oct 28

11:05 pm - 9:56 am

SFO

CAE

7h 51m

1 stop

7:45 pm - 1:15 am

CAE

SFO

8h 30m

1 stop

$384United Airlines

Mon, Jul 6 - Wed, Jul 8

9:30 pm - 9:56 am

SFO

CAE

9h 26m

1 stop

7:45 pm - 1:15 am

CAE

SFO

8h 30m

1 stop

$395United Airlines

Mon, Jul 6 - Wed, Jul 8

Frontier flights from San Francisco to South Carolina

Our best Frontier deals on San Francisco to South Carolina flight tickets

Frontier

May 31

SFO8:44 pmSan Francisco

7h 15m

1 stop

CLT6:59 amCharlotte Douglas

Jun 4

CLT7:14 pmCharlotte Douglas

8h 09m

1 stop

SFO12:23 amSan Francisco

$308

Frontier

Jun 9

SFO6:00 amSan Francisco

9h 19m

1 stop

CLT6:19 pmCharlotte Douglas

Jun 26

CLT10:14 pmCharlotte Douglas

29h 13m

1 stop

SFO12:27 amSan Francisco

$310

Frontier

Jun 9

SFO6:00 amSan Francisco

9h 19m

1 stop

CLT6:19 pmCharlotte Douglas

Jun 23

CLT7:14 pmCharlotte Douglas

8h 13m

1 stop

SFO12:27 amSan Francisco

$314

Southwest flights from San Francisco to South Carolina

Our best Southwest deals on San Francisco to South Carolina flight tickets

Southwest

Jul 8

SFO5:15 amSan Francisco

7h 25m

1 stop

CLT3:40 pmCharlotte Douglas

Jul 15

CLT7:05 pmCharlotte Douglas

8h 10m

1 stop

SFO12:15 amSan Francisco

$307

Southwest

Sep 9

SFO7:40 amSan Francisco

10h 45m

2 stops

CLT9:25 pmCharlotte Douglas

Sep 23

CLT6:35 pmCharlotte Douglas

7h 30m

1 stop

SFO11:05 pmSan Francisco

$312

Southwest

Aug 4

SFO11:40 pmSan Francisco

9h 15m

1 stop

CLT11:55 amCharlotte Douglas

Aug 22

CLT7:55 amCharlotte Douglas

8h 05m

1 stop

SFO1:00 pmSan Francisco

$346

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Sat 9/5

12:22 pm-10:49 pm

1 stop7h 27m

Charleston

Fri 9/11

6:10 am-11:09 am

1 stop7h 59m

$251

San FranciscoCharleston

SFO - CHS

SFOCHS

San Francisco

Sat 9/5

12:22 pm-10:49 pm

1 stop7h 27m

Charleston

Fri 9/11

6:10 am-11:09 am

1 stop7h 59m

$252

San FranciscoCharlotte

SFO - CLT

SFOCLT

San Francisco

Wed 7/8

5:15 am-3:40 pm

1 stop7h 25m

Charlotte Douglas

Wed 7/15

7:05 pm-12:15 am

1 stop8h 10m

$307

San FranciscoCharlotte

SFO - CLT

SFOCLT

San Francisco

Wed 9/9

7:40 am-9:25 pm

2 stops10h 45m

Charlotte Douglas

Wed 9/23

6:35 pm-11:05 pm

1 stop7h 30m

$312

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Mon 7/6

11:49 pm-10:44 am

1 stop7h 55m

Columbia Metropolitan

Wed 7/15

6:03 pm-10:48 pm

1 stop7h 45m

$329

Quickest round-trip

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Sat 7/11

11:59 pm-9:22 am

1 stop6h 23m

Columbia Metropolitan

Wed 7/15

6:01 pm-10:49 pm

1 stop7h 48m

$335

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Thu 7/16

11:59 pm-9:22 am

1 stop6h 23m

Columbia Metropolitan

Mon 7/20

3:51 pm-10:49 pm

1 stop9h 58m

$363

San FranciscoHilton Head Island

SFO - HHH

SFOHHH

San Francisco

Wed 10/21

5:54 am-5:32 pm

1 stop8h 38m

Hilton Head Island

Wed 10/28

6:13 pm-10:48 pm

1 stop7h 35m

$369

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Mon 7/6

11:05 pm-9:56 am

1 stop7h 51m

Columbia Metropolitan

Wed 7/8

7:45 pm-1:15 am

1 stop8h 30m

$384

San FranciscoColumbia

SFO - CAE

SFOCAE

San Francisco

Mon 7/6

9:30 pm-9:56 am

1 stop9h 26m

Columbia Metropolitan

Wed 7/8

7:45 pm-1:15 am

1 stop8h 30m

$395

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from San Francisco is in December. Flight prices, which tend to average around $136, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of December, then book flights to South Carolina from San Francisco during July instead. Flights to South Carolina in July, while not as cheap as those in December, still average around $136.

How far in advance should I book a flight from San Francisco to South Carolina?

You are more likely to see cheaper flights to South Carolina from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $392 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from San Francisco for as low as $306 on momondo.

Can stopping save me money on San Francisco to South Carolina flights?

You could potentially save up to 32% on your flight if you consider stops on a San Francisco to South Carolina flight.

Cheap San Francisco to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South Carolina

Fastest flight time	5h 06m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from San Francisco to South Carolina takes 5h 06m

Direct flights go from San Francisco to South Carolina every day.

There are 57 airports in South Carolina. From San Francisco there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from San Francisco to South Carolina

When did momondo last update prices for flights from San Francisco Airport to South Carolina?
Prices for flights from San Francisco Airport to South Carolina were last updated today.
How many operators does momondo search for flights from San Francisco Airport to South Carolina?
There are 7 operators available for flights from San Francisco Airport to South Carolina as of May 2026.
How old do you have to be to fly from San Francisco Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from San Francisco to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from San Francisco to South Carolina is Airbus A220-300 (100.00% of total bookings).

Best airlines flying from San Francisco to South Carolina

Compare and see reviews for airlines that fly from San Francisco to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $166	Free Cancellation	Rating 7.1 2,983 reviews	Search JetBlue flights
Breeze Airways	PriceFrom $168	Free Cancellation	Rating 8.2 286 reviews	Search Breeze Airways flights
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.1 11,639 reviews	Search American Airlines flights
Delta	PriceFrom $256	Free Cancellation	Rating 7.9 8,426 reviews	Search Delta flights
United Airlines	PriceFrom $259	Free Cancellation	Rating 7.4 9,750 reviews	Search United Airlines flights
Southwest	PriceFrom $313	Free Cancellation	Rating 7.9 4,265 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Francisco to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from San Francisco to South Carolina with flexible booking policies on momondo?

All flight searches from San Francisco to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from San Francisco.

I’m not ready to book a flight from San Francisco to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.