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Cheap flights from San Francisco to Greenville from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Greenville departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Greenville

Cheap round-trip flights

American Airlines Logo
7:00 am - 4:49 pmSFO-GSP
6h 49m1 stop
American Airlines Logo
7:14 am - 2:16 pmGSP-SFO
10h 02m1 stop
$333American Airlines
Find Deal
sáb., ago. 23 - sáb., ago. 30
American Airlines Logo
7:00 am - 4:49 pmSFO-GSP
6h 49m1 stop
American Airlines Logo
12:55 pm - 8:01 pmGSP-SFO
10h 06m2 stops
$338American Airlines
Find Deal
sáb., ago. 23 - sáb., ago. 30
American Airlines Logo
7:00 am - 4:49 pmSFO-GSP
6h 49m1 stop
American Airlines Logo
8:46 am - 2:48 pmGSP-SFO
9h 02m1 stop
$345American Airlines
Find Deal
mié., ago. 27 - dom., ago. 31
American Airlines Logo
12:30 pm - 10:58 pmSFO-GSP
7h 28m1 stop
American Airlines Logo
5:20 pm - 9:50 pmGSP-SFO
7h 30m1 stop
$346American Airlines
Find Deal
mié., sep. 17 - lun., sep. 29
Southwest Logo
9:05 pm - 9:55 amSFO-GSP
9h 50m1 stop
Southwest Logo
3:00 pm - 11:05 pmGSP-SFO
11h 05m2 stops
$351Southwest
Find Deal
vie., oct. 24 - mié., oct. 29
Southwest Logo
6:20 pm - 9:55 amSFO-GSP
12h 35m2 stops
Southwest Logo
3:00 pm - 11:05 pmGSP-SFO
11h 05m2 stops
$356Southwest
Find Deal
vie., oct. 24 - mié., oct. 29
Delta Logo
9:50 pm - 10:09 amSFO-GSP
9h 19m1 stop
Delta Logo
1:45 pm - 5:47 pmGSP-SFO
7h 02m1 stop
$396Delta
Find Deal
lun., oct. 6 - mié., oct. 8
Delta Logo
9:50 pm - 10:09 amSFO-GSP
9h 19m1 stop
Delta Logo
5:36 pm - 11:56 pmGSP-SFO
9h 20m1 stop
$406Delta
Find Deal
lun., oct. 6 - mié., oct. 8
United Airlines Logo
9:15 pm - 8:51 amSFO-GSP
8h 36m1 stop
United Airlines Logo
6:02 am - 11:13 amGSP-SFO
8h 11m1 stop
$410United Airlines
Find Deal
vie., ago. 29 - dom., ago. 31
United Airlines Logo
12:43 am - 3:46 pmSFO-GSP
12h 03m1 stop
United Airlines Logo
2:51 pm - 7:57 pmGSP-SFO
8h 06m1 stop
$553United Airlines
Find Deal
vie., ago. 22 - sáb., ago. 30

Delta flights from San Francisco to Greenville

Our best Delta deals on San Francisco to Greenville flight tickets
Delta
Oct 6
SFO9:50 pmSan Francisco
9h 19m
1 stop
GSP10:09 amGreenville
Oct 8
GSP1:45 pmGreenville
7h 02m
1 stop
SFO5:47 pmSan Francisco
$396
Find similar
Delta
Oct 6
SFO9:50 pmSan Francisco
9h 19m
1 stop
GSP10:09 amGreenville
Oct 8
GSP5:36 pmGreenville
9h 20m
1 stop
SFO11:56 pmSan Francisco
$406
Find similar
Delta
Aug 29
SFO1:41 pmSan Francisco
6h 53m
1 stop
GSP11:34 pmGreenville
Aug 31
GSP5:30 amGreenville
7h 43m
1 stop
SFO10:13 amSan Francisco
$418
Find similar

American Airlines flights from San Francisco to Greenville

Our best American Airlines deals on San Francisco to Greenville flight tickets
American Airlines
Aug 23
SFO7:00 amSan Francisco
6h 49m
1 stop
GSP4:49 pmGreenville
Aug 30
GSP7:14 amGreenville
10h 02m
1 stop
SFO2:16 pmSan Francisco
$333
Find similar
American Airlines
Aug 23
SFO7:00 amSan Francisco
6h 49m
1 stop
GSP4:49 pmGreenville
Aug 30
GSP12:55 pmGreenville
10h 06m
2 stops
SFO8:01 pmSan Francisco
$338
Find similar
American Airlines
Aug 27
SFO7:00 amSan Francisco
6h 49m
1 stop
GSP4:49 pmGreenville
Aug 31
GSP8:46 amGreenville
9h 02m
1 stop
SFO2:48 pmSan Francisco
$345
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

sáb. 8/23

7:00 am-4:49 pm

1 stop6h 49m

Greenville

sáb. 8/30

7:14 am-2:16 pm

1 stop10h 02m

$333

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

sáb. 8/23

7:00 am-4:49 pm

1 stop6h 49m

Greenville

sáb. 8/30

12:55 pm-8:01 pm

2 stops10h 06m

$338

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

mié. 8/27

7:00 am-4:49 pm

1 stop6h 49m

Greenville

dom. 8/31

8:46 am-2:48 pm

1 stop9h 02m

$345

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

mié. 9/17

12:30 pm-10:58 pm

1 stop7h 28m

Greenville

lun. 9/29

5:20 pm-9:50 pm

1 stop7h 30m

$346

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

vie. 10/24

9:05 pm-9:55 am

1 stop9h 50m

Greenville

mié. 10/29

3:00 pm-11:05 pm

2 stops11h 05m

$351

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

vie. 10/24

6:20 pm-9:55 am

2 stops12h 35m

Greenville

mié. 10/29

3:00 pm-11:05 pm

2 stops11h 05m

$356

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

lun. 10/6

9:50 pm-10:09 am

1 stop9h 19m

Greenville

mié. 10/8

1:45 pm-5:47 pm

1 stop7h 02m

$396

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

lun. 10/6

9:50 pm-10:09 am

1 stop9h 19m

Greenville

mié. 10/8

5:36 pm-11:56 pm

1 stop9h 20m

$406

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

vie. 8/29

9:15 pm-8:51 am

1 stop8h 36m

Greenville

dom. 8/31

6:02 am-11:13 am

1 stop8h 11m

$410

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

vie. 8/22

12:43 am-3:46 pm

1 stop12h 03m

Greenville

sáb. 8/30

2:51 pm-7:57 pm

1 stop8h 06m

$553

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from San Francisco to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from San Francisco averaging around $410.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from San Francisco. The lowest ticket price found for a Saturday departure recently was $393. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $714. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from San Francisco to Greenville during this time can be as low as $512. Flights to Greenville are more costly at noon, with an average ticket price of $545. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $476 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from San Francisco for as low as $255 on momondo.

How have San Francisco to Greenville flight prices changed over time?

As of July 2025, prices for San Francisco to Greenville flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Greenville (SFO to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Greenville

Best Price Found

$167

Fastest flight time

6h 22m

Direct flights

None

Airports in Greenville

1 airport
The best one-way flight to Greenville from San Francisco in the past 72 hours is $167. The best round-trip flight deal from San Francisco to Greenville found on momondo in the last 72 hours is $333.
The fastest flight from San Francisco to Greenville takes 6h 22m
There are no direct flights from San Francisco to Greenville. Popular non-direct route for this connection is San Francisco Airport - Greenville Airport.
There is 1 airport near Greenville: Greenville (GSP)
Search flight deals

  • How far is San Francisco to Greenville by plane?

    The straight-line distance from San Francisco to Greenville is 2218.5 mi. Flights usually cover this in 6h 22m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Greenville Airport?

    Prices for flights from San Francisco Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Greenville Airport?

  • How old do you have to be to fly from San Francisco Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Greenville?

Best airlines flying from San Francisco to Greenville

Compare and see reviews for airlines that fly from San Francisco to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $236Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $259Free CancellationRating
8.0
7,981 reviews
Search Delta flights
SouthwestPriceFrom $313Free CancellationRating
8.0
4,246 reviews
Search Southwest flights
United AirlinesPriceFrom $446Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Greenville?

It is quick and easy to find San Francisco to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from San Francisco to Greenville with flexible booking policies on momondo?

All flight searches from San Francisco to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from San Francisco.

I’m not ready to book a flight from San Francisco to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

An easier way to manage your Greenville trip

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