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Cheap flights from San Francisco to Greenville from $185

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:35 am - 4:27 pmSFO  San Francisco-GSP Greenville
7h 52m1 stop Dallas/Fort Worth
American Airlines Logo
6:29 am - 12:23 pmGSP  Greenville-SFO San Francisco
8h 54m1 stop Charlotte Douglas
$369American Airlines
Wed, Nov 4 - Wed, Nov 18
American Airlines Logo
5:00 am - 3:21 pmSFO  San Francisco-GSP Greenville
7h 21m1 stop Charlotte Douglas
American Airlines Logo
11:54 am - 4:51 pmGSP  Greenville-SFO San Francisco
7h 57m1 stop Charlotte Douglas
$369American Airlines
Wed, Oct 21 - Wed, Nov 4
Delta Logo
6:00 am - 6:09 pmSFO  San Francisco-GSP Greenville
9h 09m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:19 pm - 11:58 pmGSP  Greenville-SFO San Francisco
7h 39m1 stop Atlanta Hartsfield-Jackson
$369Delta
Wed, Nov 4 - Mon, Nov 9
Delta Logo
10:25 pm - 10:01 amSFO  San Francisco-GSP Greenville
8h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:19 pm - 11:58 pmGSP  Greenville-SFO San Francisco
7h 39m1 stop Atlanta Hartsfield-Jackson
$369Delta
Tue, Nov 3 - Mon, Nov 9
Southwest Logo
9:25 pm - 10:00 amSFO  San Francisco-GSP Greenville
9h 35m1 stop Baltimore/Washington
Southwest Logo
7:50 am - 2:00 pmGSP  Greenville-SFO San Francisco
9h 10m1 stop Baltimore/Washington
$369Southwest
Thu, Feb 11 - Tue, Feb 16
American Airlines Logo
5:00 am - 3:21 pmSFO  San Francisco-GSP Greenville
7h 21m1 stop Charlotte Douglas
American Airlines Logo
7:51 am - 3:10 pmGSP  Greenville-SFO San Francisco
10h 19m1 stop Dallas/Fort Worth
$369American Airlines
Wed, Oct 21 - Wed, Nov 4
Delta Logo
10:25 pm - 10:01 amSFO  San Francisco-GSP Greenville
8h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:19 pm - 11:58 pmGSP  Greenville-SFO San Francisco
7h 39m1 stop Atlanta Hartsfield-Jackson
$369Delta
Mon, Nov 2 - Mon, Nov 9
Southwest Logo
9:35 pm - 10:05 amSFO  San Francisco-GSP Greenville
9h 30m1 stop Baltimore/Washington
Southwest Logo
6:40 am - 1:05 pmGSP  Greenville-SFO San Francisco
9h 25m2 stops Nashville Intl Los Angeles
$374Southwest
Mon, Oct 26 - Mon, Nov 2
United Airlines Logo
11:30 pm - 9:58 amSFO  San Francisco-GSP Greenville
7h 28m1 stop Chicago O'Hare Intl
United Airlines Logo
6:20 am - 1:30 pmGSP  Greenville-SFO San Francisco
10h 10m1 stop Chicago O'Hare Intl
$378United Airlines
Fri, Oct 23 - Tue, Oct 27
United Airlines Logo
11:30 pm - 9:58 amSFO  San Francisco-GSP Greenville
7h 28m1 stop Chicago O'Hare Intl
United Airlines Logo
2:19 pm - 9:24 pmGSP  Greenville-SFO San Francisco
10h 05m1 stop Chicago O'Hare Intl
$378United Airlines
Fri, Oct 23 - Tue, Oct 27

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Southwest flights from San Francisco to Greenville

Our best Southwest deals on San Francisco to Greenville flight tickets
Southwest
Oct 20
SFO11:40 pmSan Francisco
10h 00m
2 stops
GSP12:40 pmGreenville
Oct 27
GSP8:30 amGreenville
9h 05m
1 stop
SFO2:35 pmSan Francisco
$374
Southwest
Oct 26
SFO11:40 pmSan Francisco
10h 00m
2 stops
GSP12:40 pmGreenville
Nov 2
GSP6:40 amGreenville
12h 00m
2 stops
SFO3:40 pmSan Francisco
$379
Southwest
Feb 11
SFO3:20 pmSan Francisco
15h 40m
2 stops
GSP10:00 amGreenville
Feb 16
GSP6:40 amGreenville
9h 15m
2 stops
SFO12:55 pmSan Francisco
$394

American Airlines flights from San Francisco to Greenville

Our best American Airlines deals on San Francisco to Greenville flight tickets
American Airlines
Oct 29
SFO5:00 amSan Francisco
7h 21m
1 stop
GSP3:21 pmGreenville
Nov 1
GSP6:42 pmGreenville
8h 13m
1 stop
SFO11:55 pmSan Francisco
$423
American Airlines
Nov 6
SFO5:00 amSan Francisco
7h 18m
1 stop
GSP3:18 pmGreenville
Nov 8
GSP5:17 pmGreenville
10h 22m
1 stop
SFO12:39 amSan Francisco
$441
American Airlines
Nov 6
SFO9:50 pmSan Francisco
9h 32m
1 stop
GSP10:22 amGreenville
Nov 8
GSP5:17 pmGreenville
10h 22m
1 stop
SFO12:39 amSan Francisco
$445

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 11/4

5:35 am-4:27 pm

1 stop7h 52m

Greenville

Wed 11/18

6:29 am-12:23 pm

1 stop8h 54m

$369
Quickest round-trip

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 10/21

5:00 am-3:21 pm

1 stop7h 21m

Greenville

Wed 11/4

11:54 am-4:51 pm

1 stop7h 57m

$369

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 11/4

6:00 am-6:09 pm

1 stop9h 09m

Greenville

Mon 11/9

7:19 pm-11:58 pm

1 stop7h 39m

$369

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Tue 11/3

10:25 pm-10:01 am

1 stop8h 36m

Greenville

Mon 11/9

7:19 pm-11:58 pm

1 stop7h 39m

$369

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Thu 2/11

9:25 pm-10:00 am

1 stop9h 35m

Greenville

Tue 2/16

7:50 am-2:00 pm

1 stop9h 10m

$369

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 10/21

5:00 am-3:21 pm

1 stop7h 21m

Greenville

Wed 11/4

7:51 am-3:10 pm

1 stop10h 19m

$369

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Mon 11/2

10:25 pm-10:01 am

1 stop8h 36m

Greenville

Mon 11/9

7:19 pm-11:58 pm

1 stop7h 39m

$369

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Mon 10/26

9:35 pm-10:05 am

1 stop9h 30m

Greenville

Mon 11/2

6:40 am-1:05 pm

2 stops9h 25m

$374

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Fri 10/23

11:30 pm-9:58 am

1 stop7h 28m

Greenville

Tue 10/27

6:20 am-1:30 pm

1 stop10h 10m

$378

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Fri 10/23

11:30 pm-9:58 am

1 stop7h 28m

Greenville

Tue 10/27

2:19 pm-9:24 pm

1 stop10h 05m

$378

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Greenville from

How to get the cheapest flight ticket from San Francisco to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $412 to $512.
The lowest price recently found on this route was $369.

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from San Francisco averaging around $423.

How have San Francisco to Greenville flight prices changed over time?

As of September 2026, prices for San Francisco to Greenville flights are approximately 15% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Greenville (SFO to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Greenville

Best Price Found

$185

Fastest flight time

7h 08m

Direct flights

None
The best one-way flight to Greenville from San Francisco in the past 72 hours is $185. The best round-trip flight deal from San Francisco to Greenville found on momondo in the last 72 hours is $369.
The fastest flight from San Francisco to Greenville takes 7h 08m
There are no direct flights from San Francisco to Greenville. There are no popular flight routes from San Francisco to Greenville.
Search flight deals

Frequently asked questions about flying from San Francisco to Greenville

  • How far is San Francisco to Greenville by plane?

    The straight-line distance from San Francisco to Greenville is 2218.0 mi. Flights usually cover this in 7h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Greenville Airport?

    Prices for flights from San Francisco Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Greenville Airport?

  • How old do you have to be to fly from San Francisco Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Greenville?

Best airlines flying from San Francisco to Greenville

Compare and see reviews for airlines that fly from San Francisco to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $336Free CancellationRating
7.8
8,591 reviews
Search Delta flights
American AirlinesPriceFrom $339Free CancellationRating
7.0
12,075 reviews
Search American Airlines flights
United AirlinesPriceFrom $424Free CancellationRating
7.4
10,226 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Greenwood
Simpsonville
Greer
Duncan
Seneca

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Greenville?

It is quick and easy to find San Francisco to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from San Francisco to Greenville with flexible booking policies on momondo?

All flight searches from San Francisco to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from San Francisco.

I’m not ready to book a flight from San Francisco to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

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