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Cheap flights from San Francisco to Greenville from $182

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Greenville departing on 8/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:26 am - 1:09 pm
SFO
-
GSP
9h 43m
1 stop
American Airlines Logo
5:28 pm - 12:43 am
GSP
-
SFO
10h 15m
1 stop
$363American Airlines
Mon, Jul 20 - Tue, Jul 28
Delta Logo
10:00 pm - 9:25 am
SFO
-
GSP
8h 25m
1 stop
Delta Logo
6:25 pm - 11:57 pm
GSP
-
SFO
8h 32m
1 stop
$372Delta
Wed, Sep 16 - Mon, Sep 21
Southwest Logo
10:25 am - 10:05 pm
SFO
-
GSP
8h 40m
2 stops
Southwest Logo
7:00 am - 1:40 pm
GSP
-
SFO
9h 40m
2 stops
$373Southwest
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
10:50 pm - 12:15 pm
SFO
-
GSP
10h 25m
1 stop
Southwest Logo
7:00 am - 1:40 pm
GSP
-
SFO
9h 40m
2 stops
$374Southwest
Tue, Jul 21 - Tue, Jul 28
American Airlines Logo
6:36 am - 7:34 pm
SFO
-
GSP
9h 58m
1 stop
American Airlines Logo
5:28 pm - 11:10 pm
GSP
-
SFO
8h 42m
1 stop
$381American Airlines
Thu, Aug 6 - Mon, Aug 17
Southwest Logo
11:40 pm - 12:25 pm
SFO
-
GSP
9h 45m
2 stops
Southwest Logo
7:00 am - 2:40 pm
GSP
-
SFO
10h 40m
2 stops
$382Southwest
Tue, Aug 18 - Thu, Aug 20
American Airlines Logo
5:30 am - 4:38 pm
SFO
-
GSP
8h 08m
1 stop
American Airlines Logo
5:28 pm - 11:10 pm
GSP
-
SFO
8h 42m
1 stop
$383American Airlines
Wed, Aug 5 - Mon, Aug 10
American Airlines Logo
5:29 am - 4:36 pm
SFO
-
GSP
8h 07m
1 stop
American Airlines Logo
5:28 pm - 12:43 am
GSP
-
SFO
10h 15m
1 stop
$386American Airlines
Wed, Jul 22 - Wed, Jul 29
Southwest Logo
10:25 am - 10:05 pm
SFO
-
GSP
8h 40m
2 stops
Southwest Logo
7:00 am - 3:45 pm
GSP
-
SFO
11h 45m
1 stop
$402Southwest
Wed, Jul 22 - Wed, Jul 29
American Airlines Logo
11:00 am - 10:17 pm
SFO
-
GSP
8h 17m
1 stop
American Airlines Logo
5:28 pm - 10:18 pm
GSP
-
SFO
7h 50m
1 stop
$403American Airlines
Thu, Aug 6 - Mon, Aug 17

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American Airlines flights from San Francisco to Greenville

Our best American Airlines deals on San Francisco to Greenville flight tickets
American Airlines
Jul 20
SFO12:26 amSan Francisco
9h 43m
1 stop
GSP1:09 pmGreenville
Jul 28
GSP5:28 pmGreenville
10h 15m
1 stop
SFO12:43 amSan Francisco
$363
American Airlines
Aug 6
SFO6:36 amSan Francisco
9h 58m
1 stop
GSP7:34 pmGreenville
Aug 17
GSP5:28 pmGreenville
8h 42m
1 stop
SFO11:10 pmSan Francisco
$381
American Airlines
Aug 5
SFO5:30 amSan Francisco
8h 08m
1 stop
GSP4:38 pmGreenville
Aug 10
GSP5:28 pmGreenville
8h 42m
1 stop
SFO11:10 pmSan Francisco
$383

Delta flights from San Francisco to Greenville

Our best Delta deals on San Francisco to Greenville flight tickets
Delta
Sep 16
SFO10:00 pmSan Francisco
8h 25m
1 stop
GSP9:25 amGreenville
Sep 21
GSP6:25 pmGreenville
8h 32m
1 stop
SFO11:57 pmSan Francisco
$372
Delta
Sep 3
SFO11:15 pmSan Francisco
7h 03m
1 stop
GSP9:18 amGreenville
Sep 8
GSP7:10 amGreenville
9h 56m
1 stop
SFO2:06 pmSan Francisco
$415
Delta
Sep 16
SFO8:59 pmSan Francisco
9h 26m
2 stops
GSP9:25 amGreenville
Sep 21
GSP6:25 pmGreenville
8h 32m
1 stop
SFO11:57 pmSan Francisco
$417

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 7/20

12:26 am-1:09 pm

1 stop9h 43m

Greenville

Tue 7/28

5:28 pm-12:43 am

1 stop10h 15m

$363

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 9/16

10:00 pm-9:25 am

1 stop8h 25m

Greenville

Mon 9/21

6:25 pm-11:57 pm

1 stop8h 32m

$372

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 7/21

10:25 am-10:05 pm

2 stops8h 40m

Greenville

Tue 7/28

7:00 am-1:40 pm

2 stops9h 40m

$373

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 7/21

10:50 pm-12:15 pm

1 stop10h 25m

Greenville

Tue 7/28

7:00 am-1:40 pm

2 stops9h 40m

$374

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 8/6

6:36 am-7:34 pm

1 stop9h 58m

Greenville

Mon 8/17

5:28 pm-11:10 pm

1 stop8h 42m

$381

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Tue 8/18

11:40 pm-12:25 pm

2 stops9h 45m

Greenville

Thu 8/20

7:00 am-2:40 pm

2 stops10h 40m

$382

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 8/5

5:30 am-4:38 pm

1 stop8h 08m

Greenville

Mon 8/10

5:28 pm-11:10 pm

1 stop8h 42m

$383

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 7/22

5:29 am-4:36 pm

1 stop8h 07m

Greenville

Wed 7/29

5:28 pm-12:43 am

1 stop10h 15m

$386

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 7/22

10:25 am-10:05 pm

2 stops8h 40m

Greenville

Wed 7/29

7:00 am-3:45 pm

1 stop11h 45m

$402
Quickest round-trip

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 8/6

11:00 am-10:17 pm

1 stop8h 17m

Greenville

Mon 8/17

5:28 pm-10:18 pm

1 stop7h 50m

$403

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Greenville from

How to get the cheapest flight ticket from San Francisco to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Greenville?

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from San Francisco averaging around $410.

How have San Francisco to Greenville flight prices changed over time?

As of June 2026, prices for San Francisco to Greenville flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Greenville (SFO to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Greenville

Fastest flight time

7h 28m

Direct flights

None
The fastest flight from San Francisco to Greenville takes 7h 28m
There are no direct flights from San Francisco to Greenville. There are no popular flight routes from San Francisco to Greenville.
Search flight deals

Frequently asked questions about flying from San Francisco to Greenville

  • How far is San Francisco to Greenville by plane?

    The straight-line distance from San Francisco to Greenville is 2218.0 mi. Flights usually cover this in 7h 28m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Greenville Airport?

    Prices for flights from San Francisco Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Greenville Airport?

  • How old do you have to be to fly from San Francisco Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Greenville?

Best airlines flying from San Francisco to Greenville

Compare and see reviews for airlines that fly from San Francisco to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $263Free CancellationRating
7.1
11,745 reviews
Search American Airlines flights
DeltaPriceFrom $366Free CancellationRating
7.8
8,424 reviews
Search Delta flights
United AirlinesPriceFrom $424Free CancellationRating
7.4
9,875 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Greenville?

It is quick and easy to find San Francisco to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from San Francisco to Greenville with flexible booking policies on momondo?

All flight searches from San Francisco to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from San Francisco.

I’m not ready to book a flight from San Francisco to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

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