Cheap flights from San Francisco to Greenville from $157

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
12:10 am - 1:26 pmSFO  San Francisco-GSP Greenville
10h 16m1 stop Chicago O'Hare Intl
United Airlines Logo
7:48 pm - 1:30 amGSP  Greenville-SFO San Francisco
8h 42m1 stop Washington, D.C. Dulles Intl
$388United Airlines
Tue, Dec 1 - Wed, Dec 2
Delta Logo
10:59 pm - 11:13 amSFO  San Francisco-GSP Greenville
9h 14m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 12:47 pmGSP  Greenville-SFO San Francisco
10h 07m1 stop Atlanta Hartsfield-Jackson
$393Delta
Tue, Dec 8 - Tue, Dec 15
Southwest Logo
7:15 am - 8:50 pmSFO  San Francisco-GSP Greenville
10h 35m2 stops San Diego Nashville Intl
Southwest Logo
8:05 am - 1:50 pmGSP  Greenville-SFO San Francisco
8h 45m1 stop Baltimore/Washington
$398Southwest
Tue, Dec 8 - Tue, Dec 15
Southwest Logo
8:20 am - 8:50 pmSFO  San Francisco-GSP Greenville
9h 30m2 stops Los Angeles Nashville Intl
Southwest Logo
11:20 am - 6:50 pmGSP  Greenville-SFO San Francisco
10h 30m2 stops Nashville Intl Austin Bergstrom
$403Southwest
Tue, Dec 8 - Tue, Dec 15
Delta Logo
11:59 pm - 9:40 amSFO  San Francisco-GSP Greenville
6h 41m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:01 am - 12:42 pmGSP  Greenville-SFO San Francisco
7h 41m1 stop Atlanta Hartsfield-Jackson
$405Delta
Wed, Dec 16 - Tue, Jan 5
American Airlines Logo
6:38 am - 4:23 pmSFO  San Francisco-GSP Greenville
6h 45m1 stop Dallas/Fort Worth
American Airlines Logo
7:44 pm - 12:45 amGSP  Greenville-SFO San Francisco
8h 01m1 stop Dallas/Fort Worth
$408American Airlines
Sat, Dec 12 - Mon, Dec 14
United Airlines Logo
11:59 pm - 11:34 amSFO  San Francisco-GSP Greenville
8h 35m1 stop Newark
United Airlines Logo
2:04 pm - 7:25 pmGSP  Greenville-SFO San Francisco
8h 21m1 stop Chicago O'Hare Intl
$433United Airlines
Fri, Dec 11 - Mon, Dec 14
American Airlines Logo
5:35 am - 4:23 pmSFO  San Francisco-GSP Greenville
7h 48m1 stop Dallas/Fort Worth
American Airlines Logo
5:17 pm - 10:31 pmGSP  Greenville-SFO San Francisco
8h 14m1 stop Dallas/Fort Worth
$465American Airlines
Thu, Dec 10 - Sun, Dec 13
Alaska Airlines Logo
6:00 am - 9:56 pmSFO  San Francisco-GSP Greenville
12h 56m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl
Alaska Airlines Logo
11:43 am - 9:50 pmGSP  Greenville-SFO San Francisco
13h 07m2 stops Chicago O'Hare Intl Seattle/Tacoma Intl
$683Alaska Airlines
Wed, Dec 16 - Tue, Jan 5
Alaska Airlines Logo
7:05 pm - 11:06 amSFO  San Francisco-GSP Greenville
13h 01m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl
Alaska Airlines Logo
11:36 am - 9:48 pmGSP  Greenville-SFO San Francisco
13h 12m2 stops Chicago O'Hare Intl Seattle/Tacoma Intl
$728Alaska Airlines
Mon, Dec 7 - Fri, Dec 11

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United Airlines flights from San Francisco to Greenville

Our best United Airlines deals on San Francisco to Greenville flight tickets
United Airlines
Dec 1
SFO12:10 amSan Francisco
10h 16m
1 stop
GSP1:26 pmGreenville
Dec 2
GSP7:48 pmGreenville
8h 42m
1 stop
SFO1:30 amSan Francisco
$388
United Airlines
Dec 11
SFO11:59 pmSan Francisco
8h 35m
1 stop
GSP11:34 amGreenville
Dec 14
GSP2:04 pmGreenville
8h 21m
1 stop
SFO7:25 pmSan Francisco
$433
United Airlines
Dec 7
SFO11:40 pmSan Francisco
7h 12m
1 stop
GSP9:52 amGreenville
Dec 11
GSP7:48 pmGreenville
8h 42m
1 stop
SFO1:30 amSan Francisco
$499

Delta flights from San Francisco to Greenville

Our best Delta deals on San Francisco to Greenville flight tickets
Delta
Dec 8
SFO10:59 pmSan Francisco
9h 14m
1 stop
GSP11:13 amGreenville
Dec 15
GSP5:40 amGreenville
10h 07m
1 stop
SFO12:47 pmSan Francisco
$393
Delta
Dec 16
SFO11:59 pmSan Francisco
6h 41m
1 stop
GSP9:40 amGreenville
Jan 5
GSP8:01 amGreenville
7h 41m
1 stop
SFO12:42 pmSan Francisco
$405
Delta
Dec 1
SFO6:00 amSan Francisco
6h 45m
1 stop
GSP3:45 pmGreenville
Dec 2
GSP12:18 pmGreenville
9h 43m
1 stop
SFO7:01 pmSan Francisco
$446

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Tue 12/1

12:10 am-1:26 pm

1 stop10h 16m

Greenville

Wed 12/2

7:48 pm-1:30 am

1 stop8h 42m

$388

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Tue 12/8

10:59 pm-11:13 am

1 stop9h 14m

Greenville

Tue 12/15

5:40 am-12:47 pm

1 stop10h 07m

$393

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Tue 12/8

7:15 am-8:50 pm

2 stops10h 35m

Greenville

Tue 12/15

8:05 am-1:50 pm

1 stop8h 45m

$398

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Tue 12/8

8:20 am-8:50 pm

2 stops9h 30m

Greenville

Tue 12/15

11:20 am-6:50 pm

2 stops10h 30m

$403
Quickest round-trip

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 12/16

11:59 pm-9:40 am

1 stop6h 41m

Greenville

Tue 1/5

8:01 am-12:42 pm

1 stop7h 41m

$405

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Sat 12/12

6:38 am-4:23 pm

1 stop6h 45m

Greenville

Mon 12/14

7:44 pm-12:45 am

1 stop8h 01m

$408

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Fri 12/11

11:59 pm-11:34 am

1 stop8h 35m

Greenville

Mon 12/14

2:04 pm-7:25 pm

1 stop8h 21m

$433

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Thu 12/10

5:35 am-4:23 pm

1 stop7h 48m

Greenville

Sun 12/13

5:17 pm-10:31 pm

1 stop8h 14m

$465

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Wed 12/16

6:00 am-9:56 pm

2 stops12h 56m

Greenville

Tue 1/5

11:43 am-9:50 pm

2 stops13h 07m

$683

San FranciscoGreenville

SFO San Francisco - GSP Greenville

SFOGSP

San Francisco

Mon 12/7

7:05 pm-11:06 am

2 stops13h 01m

Greenville

Fri 12/11

11:36 am-9:48 pm

2 stops13h 12m

$728

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from San Francisco to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $537 to $637.
The lowest price recently found on this route was $388.

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from San Francisco averaging around $423.

How have San Francisco to Greenville flight prices changed over time?

As of November 2026, prices for San Francisco to Greenville flights are approximately 29% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Greenville (SFO to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Greenville

Best Price Found

$157

Fastest flight time

6h 37m

Direct flights

None
The best one-way flight to Greenville from San Francisco in the past 72 hours is $157. The best round-trip flight deal from San Francisco to Greenville found on momondo in the last 72 hours is $388.
The fastest flight from San Francisco to Greenville takes 6h 37m
There are no direct flights from San Francisco to Greenville. There are no popular flight routes from San Francisco to Greenville.

Frequently asked questions about flying from San Francisco to Greenville

  • How far is San Francisco to Greenville by plane?

    The straight-line distance from San Francisco to Greenville is 2218.0 mi. Flights usually cover this in 6h 37m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Greenville Airport?

    Prices for flights from San Francisco Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Greenville Airport?

  • How old do you have to be to fly from San Francisco Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Greenville?

Best airlines flying from San Francisco to Greenville

Compare and see reviews for airlines that fly from San Francisco to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $336Free CancellationRating
7.8
8,700 reviews
Search Delta flights
American AirlinesPriceFrom $339Free CancellationRating
7.0
12,226 reviews
Search American Airlines flights
SouthwestPriceFrom $363Free CancellationRating
8.0
4,219 reviews
Search Southwest flights
United AirlinesPriceFrom $424Free CancellationRating
7.3
10,476 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Greenwood
Simpsonville
Greer
Duncan
Seneca

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Greenville?

It is quick and easy to find San Francisco to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from San Francisco to Greenville with flexible booking policies on momondo?

All flight searches from San Francisco to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from San Francisco.

I’m not ready to book a flight from San Francisco to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

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1 adult
Thu 12/10
Thu 12/17

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