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Cheap flights from San Diego to Greenville from $150

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:15 am - 4:51 pmSAN  San Diego-GSP Greenville
7h 36m1 stop Charlotte Douglas
American Airlines Logo
2:40 pm - 9:00 pmGSP  Greenville-SAN San Diego
9h 20m1 stop Dallas/Fort Worth
$299American Airlines
Thu, Jan 28 - Mon, Feb 1
Delta Logo
10:10 pm - 10:12 amSAN  San Diego-GSP Greenville
9h 02m1 stop Detroit Metropolitan Wayne County
Delta Logo
12:11 pm - 6:18 pmGSP  Greenville-SAN San Diego
9h 07m1 stop Atlanta Hartsfield-Jackson
$299Delta
Mon, Dec 14 - Thu, Jan 21
Delta Logo
8:00 am - 6:19 pmSAN  San Diego-GSP Greenville
7h 19m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 9:55 amGSP  Greenville-SAN San Diego
7h 15m1 stop Atlanta Hartsfield-Jackson
$299Delta
Sat, Dec 5 - Wed, Dec 9
Southwest Logo
9:15 am - 8:50 pmSAN  San Diego-GSP Greenville
8h 35m2 stops Austin Bergstrom Nashville Intl
Southwest Logo
7:10 pm - 11:00 pmGSP  Greenville-SAN San Diego
6h 50m1 stop Nashville Intl
$304Southwest
Mon, Dec 14 - Thu, Jan 21
United Airlines Logo
8:40 am - 8:59 pmSAN  San Diego-GSP Greenville
9h 19m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
6:00 am - 1:09 pmGSP  Greenville-SAN San Diego
10h 09m1 stop Newark
$304United Airlines
Sat, Dec 5 - Wed, Dec 9
Southwest Logo
9:15 am - 8:50 pmSAN  San Diego-GSP Greenville
8h 35m2 stops Austin Bergstrom Nashville Intl
Southwest Logo
7:15 am - 12:45 pmGSP  Greenville-SAN San Diego
8h 30m2 stops Nashville Intl Austin Bergstrom
$309Southwest
Mon, Dec 14 - Thu, Jan 21
United Airlines Logo
6:50 am - 4:53 pmSAN  San Diego-GSP Greenville
7h 03m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 1:09 pmGSP  Greenville-SAN San Diego
10h 09m1 stop Newark
$354United Airlines
Sun, Dec 6 - Wed, Dec 9
American Airlines Logo
7:21 am - 9:44 pmSAN  San Diego-GSP Greenville
11h 23m1 stop Chicago O'Hare Intl
American Airlines Logo
7:40 am - 2:21 pmGSP  Greenville-SAN San Diego
9h 41m1 stop Dallas/Fort Worth
$412American Airlines
Mon, Dec 21 - Fri, Dec 25
Alaska Airlines Logo
8:51 pm - 10:33 pmSAN  San Diego-GSP Greenville
22h 42m2 stops Portland Dallas/Fort Worth
Alaska Airlines Logo
7:40 am - 2:36 pmGSP  Greenville-SAN San Diego
9h 56m1 stop Dallas/Fort Worth
$765Alaska Airlines
Wed, Dec 23 - Wed, Dec 30
Breeze Airways Logo
1:13 pm - 7:59 pmSAN  San Diego-GSP Greenville
27h 46m3 stops Norfolk Providence-TFGreen Orlando
Breeze Airways Logo
4:02 pm - 12:37 pmGSP  Greenville-SAN San Diego
47h 35m2 stops Orlando Raleigh-Durham
$1,173Breeze Airways
Wed, Nov 18 - Sun, Nov 22

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American Airlines flights from San Diego to Greenville

Our best American Airlines deals on San Diego to Greenville flight tickets
American Airlines
Dec 21
SAN7:21 amSan Diego
11h 23m
1 stop
GSP9:44 pmGreenville
Dec 25
GSP7:40 amGreenville
9h 41m
1 stop
SAN2:21 pmSan Diego
$412
American Airlines
Nov 29
SAN2:18 pmSan Diego
6h 19m
1 stop
GSP11:37 pmGreenville
Dec 3
GSP2:31 pmGreenville
9h 59m
1 stop
SAN9:30 pmSan Diego
$609
American Airlines
Nov 12
SAN10:40 pmSan Diego
9h 27m
1 stop
GSP11:07 amGreenville
Nov 15
GSP7:46 pmGreenville
7h 10m
1 stop
SAN11:56 pmSan Diego
$612

United Airlines flights from San Diego to Greenville

Our best United Airlines deals on San Diego to Greenville flight tickets
United Airlines
Dec 14
SAN6:20 amSan Diego
11h 39m
2 stops
GSP8:59 pmGreenville
Jan 20
GSP6:30 amGreenville
7h 51m
1 stop
SAN11:21 amSan Diego
$304
United Airlines
Dec 6
SAN6:50 amSan Diego
7h 03m
1 stop
GSP4:53 pmGreenville
Dec 9
GSP6:00 amGreenville
10h 09m
1 stop
SAN1:09 pmSan Diego
$354
United Airlines
Nov 13
SAN9:45 pmSan Diego
9h 17m
1 stop
GSP10:02 amGreenville
Nov 15
GSP6:20 amGreenville
8h 07m
1 stop
SAN11:27 amSan Diego
$423

momondo Fare Finder

 
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Thu 1/28

6:15 am-4:51 pm

1 stop7h 36m

Greenville

Mon 2/1

2:40 pm-9:00 pm

1 stop9h 20m

$299

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Mon 12/14

10:10 pm-10:12 am

1 stop9h 02m

Greenville

Thu 1/21

12:11 pm-6:18 pm

1 stop9h 07m

$299
Quickest round-trip

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Sat 12/5

8:00 am-6:19 pm

1 stop7h 19m

Greenville

Wed 12/9

5:40 am-9:55 am

1 stop7h 15m

$299

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Mon 12/14

9:15 am-8:50 pm

2 stops8h 35m

Greenville

Thu 1/21

7:10 pm-11:00 pm

1 stop6h 50m

$304

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Sat 12/5

8:40 am-8:59 pm

2 stops9h 19m

Greenville

Wed 12/9

6:00 am-1:09 pm

1 stop10h 09m

$304

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Mon 12/14

9:15 am-8:50 pm

2 stops8h 35m

Greenville

Thu 1/21

7:15 am-12:45 pm

2 stops8h 30m

$309

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Sun 12/6

6:50 am-4:53 pm

1 stop7h 03m

Greenville

Wed 12/9

6:00 am-1:09 pm

1 stop10h 09m

$354

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Mon 12/21

7:21 am-9:44 pm

1 stop11h 23m

Greenville

Fri 12/25

7:40 am-2:21 pm

1 stop9h 41m

$412

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Wed 12/23

8:51 pm-10:33 pm

2 stops22h 42m

Greenville

Wed 12/30

7:40 am-2:36 pm

1 stop9h 56m

$765

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Wed 11/18

1:13 pm-7:59 pm

3 stops27h 46m

Greenville

Sun 11/22

4:02 pm-12:37 pm

2 stops47h 35m

$1,173

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to Greenville from

How to get the cheapest flight ticket from San Diego to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $393 to $566.
The lowest price recently found on this route was $299.

What is the cheapest month to fly to Greenville?

The month of October is another great option to travel to Greenville, with average flight prices from San Diego averaging around $423.

How have San Diego to Greenville flight prices changed over time?

As of November 2026, prices for San Diego to Greenville flights are approximately 16% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Greenville (SAN to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Greenville

Best Price Found

$150

Fastest flight time

5h 55m

Direct flights

None
The best one-way flight to Greenville from San Diego in the past 72 hours is $150. The best round-trip flight deal from San Diego to Greenville found on momondo in the last 72 hours is $299.
The fastest flight from San Diego to Greenville takes 5h 55m
There are no direct flights from San Diego to Greenville. There are no popular flight routes from San Diego to Greenville.
Search flight deals

Frequently asked questions about flying from San Diego to Greenville

  • How far is San Diego to Greenville by plane?

    There are 1990.4 mi between San Diego and Greenville. A reasonable flight in good conditions will take 5h 55m.

  • When did momondo last update prices for flights from San Diego Airport to Greenville Airport?

    Prices for flights from San Diego Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Greenville Airport?

  • How old do you have to be to fly from San Diego Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Greenville?

Best airlines flying from San Diego to Greenville

Compare and see reviews for airlines that fly from San Diego to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $298Free CancellationRating
7.0
12,228 reviews
Search American Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.8
8,701 reviews
Search Delta flights
SouthwestPriceFrom $304Free CancellationRating
8.0
4,213 reviews
Search Southwest flights
United AirlinesPriceFrom $332Free CancellationRating
7.3
10,462 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Greenwood
Simpsonville
Greer
Duncan
Seneca

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from San Diego.

Can I find flights from San Diego to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Greenville?

momondo helps you find the best flight between San Diego and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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