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Cheap flights from San Diego to Greenville from $150

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:30 pm - 9:58 amSAN  San Diego-GSP Greenville
8h 28m1 stop Chicago O'Hare Intl
United Airlines Logo
4:00 pm - 10:19 pmGSP  Greenville-SAN San Diego
9h 19m1 stop Newark
$294United Airlines
Mon, Oct 19 - Tue, Oct 20
American Airlines Logo
9:25 pm - 8:24 amSAN  San Diego-GSP Greenville
7h 59m1 stop Charlotte Douglas
American Airlines Logo
5:25 pm - 10:06 pmGSP  Greenville-SAN San Diego
7h 41m1 stop Dallas/Fort Worth
$299American Airlines
Sat, Oct 24 - Tue, Oct 27
Delta Logo
6:15 am - 4:11 pmSAN  San Diego-GSP Greenville
6h 56m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:44 pm - 9:19 pmGSP  Greenville-SAN San Diego
8h 35m1 stop Atlanta Hartsfield-Jackson
$299Delta
Thu, Nov 26 - Thu, Dec 3
Delta Logo
9:45 pm - 9:23 amSAN  San Diego-GSP Greenville
8h 38m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 12:44 pmGSP  Greenville-SAN San Diego
8h 44m1 stop Atlanta Hartsfield-Jackson
$299Delta
Mon, Oct 12 - Sat, Oct 17
United Airlines Logo
10:30 pm - 9:30 amSAN  San Diego-GSP Greenville
8h 00m1 stop Chicago O'Hare Intl
United Airlines Logo
5:12 pm - 9:26 pmGSP  Greenville-SAN San Diego
7h 14m1 stop Houston George Bush Intcntl
$299United Airlines
Wed, Oct 28 - Mon, Nov 2
Southwest Logo
9:50 pm - 10:05 amSAN  San Diego-GSP Greenville
9h 15m1 stop Baltimore/Washington
Southwest Logo
8:40 pm - 12:35 amGSP  Greenville-SAN San Diego
6h 55m1 stop Nashville Intl
$310Southwest
Mon, Oct 26 - Fri, Oct 30
American Airlines Logo
9:25 pm - 8:24 amSAN  San Diego-GSP Greenville
7h 59m1 stop Charlotte Douglas
American Airlines Logo
5:25 pm - 10:06 pmGSP  Greenville-SAN San Diego
7h 41m1 stop Dallas/Fort Worth
$310American Airlines
Fri, Oct 23 - Tue, Oct 27
Southwest Logo
9:50 pm - 10:05 amSAN  San Diego-GSP Greenville
9h 15m1 stop Baltimore/Washington
Southwest Logo
5:35 pm - 10:30 pmGSP  Greenville-SAN San Diego
7h 55m1 stop Nashville Intl
$349Southwest
Tue, Oct 13 - Sat, Oct 17
Alaska Airlines Logo
4:08 pm - 10:33 pmSAN  San Diego-GSP Greenville
27h 25m2 stops Portland Dallas/Fort Worth
Alaska Airlines Logo
3:25 pm - 10:45 pmGSP  Greenville-SAN San Diego
10h 20m1 stop Chicago O'Hare Intl
$678Alaska Airlines
Wed, Dec 23 - Wed, Dec 30
Alaska Airlines Logo
8:51 pm - 10:33 pmSAN  San Diego-GSP Greenville
22h 42m2 stops Portland Dallas/Fort Worth
Alaska Airlines Logo
11:44 am - 5:02 pmGSP  Greenville-SAN San Diego
8h 18m1 stop Chicago O'Hare Intl
$745Alaska Airlines
Wed, Dec 23 - Wed, Dec 30

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Delta flights from San Diego to Greenville

Our best Delta deals on San Diego to Greenville flight tickets
Delta
Nov 5
SAN11:31 amSan Diego
6h 56m
1 stop
GSP9:27 pmGreenville
Nov 8
GSP5:40 amGreenville
7h 00m
1 stop
SAN9:40 amSan Diego
$388
Delta
Nov 26
SAN8:00 amSan Diego
8h 55m
1 stop
GSP7:55 pmGreenville
Dec 3
GSP12:18 pmGreenville
14h 39m
2 stops
SAN11:57 pmSan Diego
$412
Delta
Oct 12
SAN9:45 pmSan Diego
8h 38m
1 stop
GSP9:23 amGreenville
Oct 17
GSP5:40 amGreenville
12h 24m
2 stops
SAN3:04 pmSan Diego
$432

Alaska Airlines flights from San Diego to Greenville

Our best Alaska Airlines deals on San Diego to Greenville flight tickets
Alaska Airlines
Sep 23
SAN7:03 amSan Diego
7h 50m
1 stop
GSP5:53 pmGreenville
Sep 30
GSP8:01 amGreenville
14h 53m
2 stops
SAN7:54 pmSan Diego
$736
Alaska Airlines
Sep 24
SAN4:02 pmSan Diego
22h 51m
2 stops
GSP5:53 pmGreenville
Oct 1
GSP11:33 amGreenville
8h 22m
1 stop
SAN4:55 pmSan Diego
$858

momondo Fare Finder

 
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Mon 10/19

10:30 pm-9:58 am

1 stop8h 28m

Greenville

Tue 10/20

4:00 pm-10:19 pm

1 stop9h 19m

$294

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Sat 10/24

9:25 pm-8:24 am

1 stop7h 59m

Greenville

Tue 10/27

5:25 pm-10:06 pm

1 stop7h 41m

$299

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Thu 11/26

6:15 am-4:11 pm

1 stop6h 56m

Greenville

Thu 12/3

3:44 pm-9:19 pm

1 stop8h 35m

$299

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Mon 10/12

9:45 pm-9:23 am

1 stop8h 38m

Greenville

Sat 10/17

7:00 am-12:44 pm

1 stop8h 44m

$299
Quickest round-trip

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Wed 10/28

10:30 pm-9:30 am

1 stop8h 00m

Greenville

Mon 11/2

5:12 pm-9:26 pm

1 stop7h 14m

$299

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Mon 10/26

9:50 pm-10:05 am

1 stop9h 15m

Greenville

Fri 10/30

8:40 pm-12:35 am

1 stop6h 55m

$310

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Fri 10/23

9:25 pm-8:24 am

1 stop7h 59m

Greenville

Tue 10/27

5:25 pm-10:06 pm

1 stop7h 41m

$310

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Tue 10/13

9:50 pm-10:05 am

1 stop9h 15m

Greenville

Sat 10/17

5:35 pm-10:30 pm

1 stop7h 55m

$349

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Wed 12/23

4:08 pm-10:33 pm

2 stops27h 25m

Greenville

Wed 12/30

3:25 pm-10:45 pm

1 stop10h 20m

$678

San DiegoGreenville

SAN San Diego - GSP Greenville

SANGSP

San Diego

Wed 12/23

8:51 pm-10:33 pm

2 stops22h 42m

Greenville

Wed 12/30

11:44 am-5:02 pm

1 stop8h 18m

$745

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Greenville from

How to get the cheapest flight ticket from San Diego to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $443 to $580.
The lowest price recently found on this route was $294.

What is the cheapest month to fly to Greenville?

The month of May is another great option to travel to Greenville, with average flight prices from San Diego averaging around $443.

How have San Diego to Greenville flight prices changed over time?

As of September 2026, prices for San Diego to Greenville flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Greenville (SAN to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Greenville

Best Price Found

$150

Fastest flight time

6h 54m

Direct flights

None
The best one-way flight to Greenville from San Diego in the past 72 hours is $150. The best round-trip flight deal from San Diego to Greenville found on momondo in the last 72 hours is $294.
The fastest flight from San Diego to Greenville takes 6h 54m
There are no direct flights from San Diego to Greenville. There are no popular flight routes from San Diego to Greenville.
Search flight deals

Frequently asked questions about flying from San Diego to Greenville

  • How far is San Diego to Greenville by plane?

    There are 1990.4 mi between San Diego and Greenville. A reasonable flight in good conditions will take 6h 54m.

  • When did momondo last update prices for flights from San Diego Airport to Greenville Airport?

    Prices for flights from San Diego Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Greenville Airport?

  • How old do you have to be to fly from San Diego Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Greenville?

Best airlines flying from San Diego to Greenville

Compare and see reviews for airlines that fly from San Diego to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $298Free CancellationRating
7.0
12,082 reviews
Search American Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.8
8,595 reviews
Search Delta flights
United AirlinesPriceFrom $332Free CancellationRating
7.4
10,225 reviews
Search United Airlines flights
SouthwestPriceFrom $335Free CancellationRating
8.0
4,195 reviews
Search Southwest flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Greenwood
Simpsonville
Greer
Duncan
Seneca

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from San Diego.

Can I find flights from San Diego to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Greenville?

momondo helps you find the best flight between San Diego and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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