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Cheap flights from San Diego to Greenville from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Greenville departing on 7/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:32 pm - 10:59 pm
SAN
-
GSP
7h 27m
1 stop
Delta Logo
11:10 am - 6:14 pm
GSP
-
SAN
10h 04m
1 stop
$305Delta
Wed, Aug 26 - Mon, Aug 31
United Airlines Logo
9:45 pm - 10:35 am
SAN
-
GSP
9h 50m
2 stops
United Airlines Logo
4:33 pm - 8:34 pm
GSP
-
SAN
7h 01m
1 stop
$311United Airlines
Wed, Aug 26 - Mon, Aug 31
Southwest Logo
10:40 pm - 12:30 pm
SAN
-
GSP
10h 50m
2 stops
Southwest Logo
1:05 pm - 6:45 pm
GSP
-
SAN
8h 40m
2 stops
$322Southwest
Wed, Aug 26 - Mon, Aug 31
United Airlines Logo
10:25 pm - 9:55 am
SAN
-
GSP
8h 30m
1 stop
United Airlines Logo
4:33 pm - 10:27 pm
GSP
-
SAN
8h 54m
1 stop
$336United Airlines
Mon, Jul 27 - Fri, Aug 14
Southwest Logo
11:55 am - 8:55 pm
SAN
-
GSP
6h 00m
1 stop
Southwest Logo
1:05 pm - 6:50 pm
GSP
-
SAN
8h 45m
1 stop
$343Southwest
Wed, Aug 5 - Fri, Aug 7
Delta Logo
10:30 pm - 9:13 am
SAN
-
GSP
7h 43m
1 stop
Delta Logo
5:16 pm - 10:57 pm
GSP
-
SAN
8h 41m
1 stop
$351Delta
Tue, Jul 21 - Thu, Jul 30
Breeze Airways Logo
12:24 pm - 11:26 am
SAN
-
GSP
20h 02m
1 stop
Breeze Airways Logo
10:35 am - 11:48 am
GSP
-
SAN
28h 13m
1 stop
$353Breeze Airways
Thu, Aug 27 - Sun, Aug 30
Southwest Logo
11:55 am - 8:55 pm
SAN
-
GSP
6h 00m
1 stop
Southwest Logo
1:05 pm - 9:55 pm
GSP
-
SAN
11h 50m
2 stops
$354Southwest
Wed, Aug 5 - Fri, Aug 7
United Airlines Logo
8:32 pm - 9:55 am
SAN
-
GSP
10h 23m
2 stops
United Airlines Logo
4:15 pm - 8:46 pm
GSP
-
SAN
7h 31m
1 stop
$356United Airlines
Tue, Aug 4 - Wed, Aug 5
Southwest Logo
10:40 pm - 12:15 pm
SAN
-
GSP
10h 35m
1 stop
Southwest Logo
1:50 pm - 11:30 pm
GSP
-
SAN
12h 40m
1 stop
$362Southwest
Tue, Jul 7 - Tue, Jul 14

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Delta flights from San Diego to Greenville

Our best Delta deals on San Diego to Greenville flight tickets
Delta
Aug 26
SAN12:32 pmSan Diego
7h 27m
1 stop
GSP10:59 pmGreenville
Aug 31
GSP11:10 amGreenville
10h 04m
1 stop
SAN6:14 pmSan Diego
$305
Delta
Jul 21
SAN10:30 pmSan Diego
7h 43m
1 stop
GSP9:13 amGreenville
Jul 30
GSP5:16 pmGreenville
8h 41m
1 stop
SAN10:57 pmSan Diego
$351
Delta
Sep 26
SAN10:30 pmSan Diego
7h 44m
1 stop
GSP9:14 amGreenville
Oct 2
GSP7:00 amGreenville
7h 16m
1 stop
SAN11:16 amSan Diego
$369

United Airlines flights from San Diego to Greenville

Our best United Airlines deals on San Diego to Greenville flight tickets
United Airlines
Aug 26
SAN9:45 pmSan Diego
9h 50m
2 stops
GSP10:35 amGreenville
Aug 31
GSP4:33 pmGreenville
7h 01m
1 stop
SAN8:34 pmSan Diego
$311
United Airlines
Jul 27
SAN10:25 pmSan Diego
8h 30m
1 stop
GSP9:55 amGreenville
Aug 14
GSP4:33 pmGreenville
8h 54m
1 stop
SAN10:27 pmSan Diego
$336
United Airlines
Aug 4
SAN8:32 pmSan Diego
10h 23m
2 stops
GSP9:55 amGreenville
Aug 5
GSP4:15 pmGreenville
7h 31m
1 stop
SAN8:46 pmSan Diego
$356

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 8/26

12:32 pm-10:59 pm

1 stop7h 27m

Greenville

Mon 8/31

11:10 am-6:14 pm

1 stop10h 04m

$305

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 8/26

9:45 pm-10:35 am

2 stops9h 50m

Greenville

Mon 8/31

4:33 pm-8:34 pm

1 stop7h 01m

$311

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 8/26

10:40 pm-12:30 pm

2 stops10h 50m

Greenville

Mon 8/31

1:05 pm-6:45 pm

2 stops8h 40m

$322

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Mon 7/27

10:25 pm-9:55 am

1 stop8h 30m

Greenville

Fri 8/14

4:33 pm-10:27 pm

1 stop8h 54m

$336
Quickest round-trip

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 8/5

11:55 am-8:55 pm

1 stop6h 00m

Greenville

Fri 8/7

1:05 pm-6:50 pm

1 stop8h 45m

$343

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 7/21

10:30 pm-9:13 am

1 stop7h 43m

Greenville

Thu 7/30

5:16 pm-10:57 pm

1 stop8h 41m

$351

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Thu 8/27

12:24 pm-11:26 am

1 stop20h 02m

Greenville

Sun 8/30

10:35 am-11:48 am

1 stop28h 13m

$353

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 8/5

11:55 am-8:55 pm

1 stop6h 00m

Greenville

Fri 8/7

1:05 pm-9:55 pm

2 stops11h 50m

$354

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 8/4

8:32 pm-9:55 am

2 stops10h 23m

Greenville

Wed 8/5

4:15 pm-8:46 pm

1 stop7h 31m

$356

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 7/7

10:40 pm-12:15 pm

1 stop10h 35m

Greenville

Tue 7/14

1:50 pm-11:30 pm

1 stop12h 40m

$362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from San Diego to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Greenville?

What is the cheapest month to fly to Greenville?

The month of October is another great option to travel to Greenville, with average flight prices from San Diego averaging around $441.

How have San Diego to Greenville flight prices changed over time?

As of June 2026, prices for San Diego to Greenville flights are approximately 8% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Greenville (SAN to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Greenville

Fastest flight time

6h 28m

Direct flights

None
The fastest flight from San Diego to Greenville takes 6h 28m
There are no direct flights from San Diego to Greenville. There are no popular flight routes from San Diego to Greenville.
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Frequently asked questions about flying from San Diego to Greenville

  • How far is San Diego to Greenville by plane?

    There are 1990.4 mi between San Diego and Greenville. A reasonable flight in good conditions will take 6h 28m.

  • When did momondo last update prices for flights from San Diego Airport to Greenville Airport?

    Prices for flights from San Diego Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Greenville Airport?

  • How old do you have to be to fly from San Diego Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Greenville?

Best airlines flying from San Diego to Greenville

Compare and see reviews for airlines that fly from San Diego to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $302Free CancellationRating
7.1
11,650 reviews
Search American Airlines flights
DeltaPriceFrom $312Free CancellationRating
7.9
8,404 reviews
Search Delta flights
United AirlinesPriceFrom $358Free CancellationRating
7.4
9,813 reviews
Search United Airlines flights
SouthwestPriceFrom $398Free CancellationRating
7.9
4,235 reviews
Search Southwest flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from San Diego.

Can I find flights from San Diego to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Greenville?

momondo helps you find the best flight between San Diego and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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