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Cheap flights from San Diego to Greenville from $138

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Greenville departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from San Diego to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:20 am - 4:54 pm
SAN
-
GSP
7h 34m
1 stop
United Airlines Logo
4:41 pm - 9:26 pm
GSP
-
SAN
7h 45m
1 stop
$367United Airlines
Wed, Apr 22 - Tue, Apr 28
United Airlines Logo
7:40 pm - 9:46 am
SAN
-
GSP
11h 06m
2 stops
United Airlines Logo
7:00 am - 11:04 am
GSP
-
SAN
7h 04m
1 stop
$372United Airlines
Wed, Apr 22 - Tue, Apr 28
Delta Logo
10:30 pm - 9:09 am
SAN
-
GSP
7h 39m
1 stop
Delta Logo
6:26 pm - 11:06 pm
GSP
-
SAN
7h 40m
1 stop
$373Delta
Wed, Apr 15 - Thu, Apr 23
Southwest Logo
10:20 am - 9:40 pm
SAN
-
GSP
8h 20m
2 stops
Southwest Logo
6:25 pm - 10:55 pm
GSP
-
SAN
7h 30m
1 stop
$378Southwest
Tue, Apr 28 - Thu, Apr 30
Delta Logo
10:30 pm - 9:09 am
SAN
-
GSP
7h 39m
1 stop
Delta Logo
6:26 pm - 11:06 pm
GSP
-
SAN
7h 40m
1 stop
$379Delta
Sat, Apr 18 - Thu, Apr 23
Southwest Logo
9:15 am - 9:40 pm
SAN
-
GSP
9h 25m
2 stops
Southwest Logo
12:50 pm - 6:40 pm
GSP
-
SAN
8h 50m
2 stops
$383Southwest
Wed, Apr 22 - Wed, Apr 29
Southwest Logo
10:20 am - 9:40 pm
SAN
-
GSP
8h 20m
2 stops
Southwest Logo
5:05 pm - 9:20 pm
GSP
-
SAN
7h 15m
1 stop
$384Southwest
Wed, Apr 29 - Wed, May 13
Southwest Logo
9:15 am - 9:40 pm
SAN
-
GSP
9h 25m
2 stops
Southwest Logo
12:50 pm - 6:25 pm
GSP
-
SAN
8h 35m
2 stops
$389Southwest
Wed, Apr 22 - Tue, Apr 28
Southwest Logo
6:45 am - 9:40 pm
SAN
-
GSP
11h 55m
2 stops
Southwest Logo
6:45 am - 12:10 pm
GSP
-
SAN
8h 25m
2 stops
$395Southwest
Wed, Apr 8 - Wed, Apr 15
Delta Logo
9:45 pm - 9:09 am
SAN
-
GSP
8h 24m
1 stop
Delta Logo
5:40 am - 9:49 am
GSP
-
SAN
7h 09m
1 stop
$407Delta
Tue, Apr 14 - Sun, Apr 19

United Airlines flights from San Diego to Greenville

Our best United Airlines deals on San Diego to Greenville flight tickets
United Airlines
Apr 15
SAN9:45 pmSan Diego
9h 10m
1 stop
GSP9:55 amGreenville
Apr 22
GSP6:30 amGreenville
7h 55m
1 stop
SAN11:25 amSan Diego
$367
United Airlines
Apr 22
SAN7:40 pmSan Diego
11h 06m
2 stops
GSP9:46 amGreenville
Apr 28
GSP7:00 amGreenville
7h 04m
1 stop
SAN11:04 amSan Diego
$372
United Airlines
Apr 23
SAN8:37 pmSan Diego
10h 09m
2 stops
GSP9:46 amGreenville
Apr 24
GSP5:41 pmGreenville
8h 18m
1 stop
SAN10:59 pmSan Diego
$438

Delta flights from San Diego to Greenville

Our best Delta deals on San Diego to Greenville flight tickets
Delta
Apr 15
SAN9:45 pmSan Diego
8h 24m
1 stop
GSP9:09 amGreenville
Apr 20
GSP6:26 pmGreenville
7h 40m
1 stop
SAN11:06 pmSan Diego
$373
Delta
Apr 18
SAN6:15 amSan Diego
8h 22m
1 stop
GSP5:37 pmGreenville
Apr 20
GSP6:26 pmGreenville
7h 40m
1 stop
SAN11:06 pmSan Diego
$379
Delta
Apr 14
SAN9:45 pmSan Diego
8h 24m
1 stop
GSP9:09 amGreenville
Apr 19
GSP5:40 amGreenville
7h 09m
1 stop
SAN9:49 amSan Diego
$407

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 4/22

6:20 am-4:54 pm

1 stop7h 34m

Greenville

Tue 4/28

4:41 pm-9:26 pm

1 stop7h 45m

$367

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 4/22

7:40 pm-9:46 am

2 stops11h 06m

Greenville

Tue 4/28

7:00 am-11:04 am

1 stop7h 04m

$372

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 4/15

10:30 pm-9:09 am

1 stop7h 39m

Greenville

Thu 4/23

6:26 pm-11:06 pm

1 stop7h 40m

$373

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 4/28

10:20 am-9:40 pm

2 stops8h 20m

Greenville

Thu 4/30

6:25 pm-10:55 pm

1 stop7h 30m

$378

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Sat 4/18

10:30 pm-9:09 am

1 stop7h 39m

Greenville

Thu 4/23

6:26 pm-11:06 pm

1 stop7h 40m

$379

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 4/22

9:15 am-9:40 pm

2 stops9h 25m

Greenville

Wed 4/29

12:50 pm-6:40 pm

2 stops8h 50m

$383

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 4/29

10:20 am-9:40 pm

2 stops8h 20m

Greenville

Wed 5/13

5:05 pm-9:20 pm

1 stop7h 15m

$384

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 4/22

9:15 am-9:40 pm

2 stops9h 25m

Greenville

Tue 4/28

12:50 pm-6:25 pm

2 stops8h 35m

$389

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 4/8

6:45 am-9:40 pm

2 stops11h 55m

Greenville

Wed 4/15

6:45 am-12:10 pm

2 stops8h 25m

$395

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 4/14

9:45 pm-9:09 am

1 stop8h 24m

Greenville

Sun 4/19

5:40 am-9:49 am

1 stop7h 09m

$407

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from San Diego to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from San Diego averaging around $361.

How have San Diego to Greenville flight prices changed over time?

As of March 2026, prices for San Diego to Greenville flights are approximately 29% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Greenville (SAN to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Greenville

Fastest flight time

8h 20m

Direct flights

None
The fastest flight from San Diego to Greenville takes 8h 20m
There are no direct flights from San Diego to Greenville. There are no popular flight routes from San Diego to Greenville.
Search flight deals

  • How far is San Diego to Greenville by plane?

    There are 1990.4 mi between San Diego and Greenville. A reasonable flight in good conditions will take 8h 20m.

  • When did momondo last update prices for flights from San Diego Airport to Greenville Airport?

    Prices for flights from San Diego Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Greenville Airport?

  • How old do you have to be to fly from San Diego Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Greenville?

Best airlines flying from San Diego to Greenville

Compare and see reviews for airlines that fly from San Diego to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $286Free CancellationRating
7.1
11,413 reviews
Search American Airlines flights
DeltaPriceFrom $312Free CancellationRating
7.9
8,276 reviews
Search Delta flights
United AirlinesPriceFrom $358Free CancellationRating
7.4
9,409 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from San Diego.

Can I find flights from San Diego to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Greenville?

momondo helps you find the best flight between San Diego and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Greenville trip

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