Cheap flights from San Diego to Greenville from $163

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Greenville departing on 8/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

American Airlines Logo
10:32 pm - 8:57 amSAN-GSP
7h 25m1 stop
American Airlines Logo
12:16 pm - 3:53 pmGSP-SAN
6h 37m1 stop
$333American Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
United Airlines Logo
8:05 am - 10:58 pmSAN-GSP
11h 53m2 stops
United Airlines Logo
2:51 pm - 8:19 pmGSP-SAN
8h 28m1 stop
$338United Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
11:30 am - 10:30 pmSAN-GSP
8h 00m1 stop
American Airlines Logo
6:33 pm - 10:36 pmGSP-SAN
7h 03m1 stop
$346American Airlines
Find Deal
Tue, Sep 9 - Mon, Sep 15
Southwest Logo
4:30 pm - 9:50 amSAN-GSP
14h 20m2 stops
Southwest Logo
1:50 pm - 9:35 pmGSP-SAN
10h 45m1 stop
$351Southwest
Find Deal
Tue, Sep 9 - Mon, Sep 15
Southwest Logo
6:55 am - 6:05 pmSAN-GSP
8h 10m1 stop
Southwest Logo
10:25 am - 6:45 pmGSP-SAN
11h 20m2 stops
$356Southwest
Find Deal
Wed, Aug 27 - Wed, Sep 3
American Airlines Logo
9:19 pm - 9:25 amSAN-GSP
9h 06m1 stop
American Airlines Logo
2:35 pm - 6:42 pmGSP-SAN
7h 07m1 stop
$359American Airlines
Find Deal
Fri, Sep 26 - Sun, Sep 28
Delta Logo
10:20 pm - 10:48 amSAN-GSP
9h 28m1 stop
Delta Logo
3:42 pm - 9:35 pmGSP-SAN
8h 53m1 stop
$363Delta
Find Deal
Fri, Nov 7 - Tue, Nov 11
Southwest Logo
6:40 pm - 10:00 amSAN-GSP
12h 20m2 stops
Southwest Logo
1:40 pm - 8:15 pmGSP-SAN
9h 35m2 stops
$373Southwest
Find Deal
Mon, Nov 3 - Sat, Nov 8
Delta Logo
10:20 pm - 10:48 amSAN-GSP
9h 28m1 stop
Delta Logo
3:42 pm - 9:35 pmGSP-SAN
8h 53m1 stop
$376Delta
Find Deal
Fri, Nov 7 - Mon, Nov 10
United Airlines Logo
8:05 am - 10:58 pmSAN-GSP
11h 53m2 stops
United Airlines Logo
9:17 am - 7:42 pmGSP-SAN
13h 25m2 stops
$443United Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20

United Airlines flights from San Diego to Greenville

Our best United Airlines deals on San Diego to Greenville flight tickets
United Airlines
Sep 13
SAN8:05 amSan Diego
11h 53m
2 stops
GSP10:58 pmGreenville
Sep 20
GSP2:51 pmGreenville
8h 28m
1 stop
SAN8:19 pmSan Diego
United Airlines
Sep 13
SAN8:05 amSan Diego
11h 53m
2 stops
GSP10:58 pmGreenville
Sep 20
GSP9:17 amGreenville
13h 25m
2 stops
SAN7:42 pmSan Diego
United Airlines
Sep 15
SAN9:41 pmSan Diego
8h 10m
1 stop
GSP8:51 amGreenville
Oct 7
GSP5:00 pmGreenville
9h 41m
2 stops
SAN11:41 pmSan Diego

American Airlines flights from San Diego to Greenville

Our best American Airlines deals on San Diego to Greenville flight tickets
American Airlines
Sep 13
SAN10:32 pmSan Diego
7h 25m
1 stop
GSP8:57 amGreenville
Sep 20
GSP12:16 pmGreenville
6h 37m
1 stop
SAN3:53 pmSan Diego
American Airlines
Sep 9
SAN11:30 amSan Diego
8h 00m
1 stop
GSP10:30 pmGreenville
Sep 15
GSP6:33 pmGreenville
7h 03m
1 stop
SAN10:36 pmSan Diego
American Airlines
Sep 26
SAN9:19 pmSan Diego
9h 06m
1 stop
GSP9:25 amGreenville
Sep 28
GSP2:35 pmGreenville
7h 07m
1 stop
SAN6:42 pmSan Diego

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Sat 9/13

10:32 pm-8:57 am

1 stop7h 25m

Greenville

Sat 9/20

12:16 pm-3:53 pm

1 stop6h 37m

$333

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Sat 9/13

8:05 am-10:58 pm

2 stops11h 53m

Greenville

Sat 9/20

2:51 pm-8:19 pm

1 stop8h 28m

$338

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 9/9

11:30 am-10:30 pm

1 stop8h 00m

Greenville

Mon 9/15

6:33 pm-10:36 pm

1 stop7h 03m

$346

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 9/9

4:30 pm-9:50 am

2 stops14h 20m

Greenville

Mon 9/15

1:50 pm-9:35 pm

1 stop10h 45m

$351

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 8/27

6:55 am-6:05 pm

1 stop8h 10m

Greenville

Wed 9/3

10:25 am-6:45 pm

2 stops11h 20m

$356

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Fri 9/26

9:19 pm-9:25 am

1 stop9h 06m

Greenville

Sun 9/28

2:35 pm-6:42 pm

1 stop7h 07m

$359

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Fri 11/7

10:20 pm-10:48 am

1 stop9h 28m

Greenville

Tue 11/11

3:42 pm-9:35 pm

1 stop8h 53m

$363

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Mon 11/3

6:40 pm-10:00 am

2 stops12h 20m

Greenville

Sat 11/8

1:40 pm-8:15 pm

2 stops9h 35m

$373

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Fri 11/7

10:20 pm-10:48 am

1 stop9h 28m

Greenville

Mon 11/10

3:42 pm-9:35 pm

1 stop8h 53m

$376

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Sat 9/13

8:05 am-10:58 pm

2 stops11h 53m

Greenville

Sat 9/20

9:17 am-7:42 pm

2 stops13h 25m

$443

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from San Diego to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of April is another great option to travel to Greenville, with average flight prices from San Diego averaging around $362.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from San Diego. The lowest ticket price found for a Wednesday departure recently was $441. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $534. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from San Diego to Greenville during this time can be as low as $464. Flights to Greenville are more costly at noon, with an average ticket price of $497. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $425 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from San Diego for as low as $368 on momondo.

How have San Diego to Greenville flight prices changed over time?

As of July 2025, prices for San Diego to Greenville flights are approximately 33% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Greenville (SAN to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Greenville

Best Price Found

$163

Fastest flight time

6h 05m

Direct flights

None

Airports in Greenville

1 airport
The best one-way flight to Greenville from San Diego in the past 72 hours is $163. The best round-trip flight deal from San Diego to Greenville found on momondo in the last 72 hours is $333.
The fastest flight from San Diego to Greenville takes 6h 05m
There are no direct flights from San Diego to Greenville. Popular non-direct route for this connection is San Diego Airport - Greenville Airport.
There is 1 airport near Greenville: Greenville (GSP)

  • How far is San Diego to Greenville by plane?

    There are 1990.4 mi between San Diego and Greenville. A reasonable flight in good conditions will take 6h 05m.

  • When did momondo last update prices for flights from San Diego Airport to Greenville Airport?

    Prices for flights from San Diego Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Greenville Airport?

  • How old do you have to be to fly from San Diego Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Greenville?


Best airlines flying from San Diego to Greenville

Compare and see reviews for airlines that fly from San Diego to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $249Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $306Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from San Diego.

Can I find flights from San Diego to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Greenville?

momondo helps you find the best flight between San Diego and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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1 adult
Tue 8/5
Tue 8/12

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