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Cheap flights from San Diego to Greenville from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Greenville departing on 5/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:53 pm - 11:59 pm
SAN
-
GSP
8h 06m
1 stop
American Airlines Logo
5:25 pm - 10:39 pm
GSP
-
SAN
8h 14m
1 stop
$353American Airlines
Wed, May 13 - Thu, May 28
American Airlines Logo
7:15 am - 4:21 pm
SAN
-
GSP
6h 06m
1 stop
American Airlines Logo
5:12 pm - 11:56 pm
GSP
-
SAN
9h 44m
1 stop
$357American Airlines
Tue, May 12 - Wed, May 13
United Airlines Logo
9:45 pm - 9:55 am
SAN
-
GSP
9h 10m
1 stop
United Airlines Logo
5:41 pm - 10:34 pm
GSP
-
SAN
7h 53m
1 stop
$383United Airlines
Tue, Jun 2 - Tue, Jun 9
United Airlines Logo
6:40 am - 6:27 pm
SAN
-
GSP
8h 47m
1 stop
United Airlines Logo
5:10 pm - 9:24 pm
GSP
-
SAN
7h 14m
1 stop
$399United Airlines
Sat, May 23 - Sat, May 30
United Airlines Logo
8:32 pm - 10:11 am
SAN
-
GSP
10h 39m
2 stops
United Airlines Logo
5:10 pm - 9:24 pm
GSP
-
SAN
7h 14m
1 stop
$404United Airlines
Sat, May 23 - Sat, May 30
Delta Logo
6:15 am - 4:10 pm
SAN
-
GSP
6h 55m
1 stop
Delta Logo
5:44 am - 9:33 am
GSP
-
SAN
6h 49m
1 stop
$409Delta
Wed, Jun 10 - Sun, Jun 14
American Airlines Logo
1:31 pm - 11:57 pm
SAN
-
GSP
7h 26m
1 stop
American Airlines Logo
6:00 am - 11:16 am
GSP
-
SAN
8h 16m
1 stop
$416American Airlines
Fri, May 15 - Tue, May 19
Delta Logo
11:33 am - 9:38 pm
SAN
-
GSP
7h 05m
1 stop
Delta Logo
7:42 pm - 11:27 pm
GSP
-
SAN
6h 45m
1 stop
$417Delta
Thu, May 14 - Mon, May 18
Southwest Logo
10:05 am - 9:40 pm
SAN
-
GSP
8h 35m
2 stops
Southwest Logo
1:50 pm - 10:00 pm
GSP
-
SAN
11h 10m
1 stop
$426Southwest
Wed, May 13 - Thu, May 28
Southwest Logo
9:15 am - 9:40 pm
SAN
-
GSP
9h 25m
2 stops
Southwest Logo
1:50 pm - 11:25 pm
GSP
-
SAN
12h 35m
1 stop
$436Southwest
Tue, Jun 2 - Tue, Jun 9

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American Airlines flights from San Diego to Greenville

Our best American Airlines deals on San Diego to Greenville flight tickets
American Airlines
May 13
SAN12:53 pmSan Diego
8h 06m
1 stop
GSP11:59 pmGreenville
May 28
GSP5:25 pmGreenville
8h 14m
1 stop
SAN10:39 pmSan Diego
$353
American Airlines
May 12
SAN7:15 amSan Diego
6h 06m
1 stop
GSP4:21 pmGreenville
May 13
GSP5:12 pmGreenville
9h 44m
1 stop
SAN11:56 pmSan Diego
$357
American Airlines
May 15
SAN1:31 pmSan Diego
7h 26m
1 stop
GSP11:57 pmGreenville
May 19
GSP6:00 amGreenville
8h 16m
1 stop
SAN11:16 amSan Diego
$416

Delta flights from San Diego to Greenville

Our best Delta deals on San Diego to Greenville flight tickets
Delta
Jun 10
SAN6:15 amSan Diego
6h 55m
1 stop
GSP4:10 pmGreenville
Jun 14
GSP5:44 amGreenville
6h 49m
1 stop
SAN9:33 amSan Diego
$409
Delta
May 14
SAN11:33 amSan Diego
7h 05m
1 stop
GSP9:38 pmGreenville
May 18
GSP7:42 pmGreenville
6h 45m
1 stop
SAN11:27 pmSan Diego
$417
Delta
May 12
SAN10:25 pmSan Diego
9h 10m
1 stop
GSP10:35 amGreenville
May 17
GSP8:45 amGreenville
6h 53m
1 stop
SAN12:38 pmSan Diego
$519

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 26, 2026.
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 5/13

12:53 pm-11:59 pm

1 stop8h 06m

Greenville

Thu 5/28

5:25 pm-10:39 pm

1 stop8h 14m

$353

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 5/12

7:15 am-4:21 pm

1 stop6h 06m

Greenville

Wed 5/13

5:12 pm-11:56 pm

1 stop9h 44m

$357

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 6/2

9:45 pm-9:55 am

1 stop9h 10m

Greenville

Tue 6/9

5:41 pm-10:34 pm

1 stop7h 53m

$383

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Sat 5/23

6:40 am-6:27 pm

1 stop8h 47m

Greenville

Sat 5/30

5:10 pm-9:24 pm

1 stop7h 14m

$399

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Sat 5/23

8:32 pm-10:11 am

2 stops10h 39m

Greenville

Sat 5/30

5:10 pm-9:24 pm

1 stop7h 14m

$404
Quickest round-trip

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 6/10

6:15 am-4:10 pm

1 stop6h 55m

Greenville

Sun 6/14

5:44 am-9:33 am

1 stop6h 49m

$409

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Fri 5/15

1:31 pm-11:57 pm

1 stop7h 26m

Greenville

Tue 5/19

6:00 am-11:16 am

1 stop8h 16m

$416

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Thu 5/14

11:33 am-9:38 pm

1 stop7h 05m

Greenville

Mon 5/18

7:42 pm-11:27 pm

1 stop6h 45m

$417

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Wed 5/13

10:05 am-9:40 pm

2 stops8h 35m

Greenville

Thu 5/28

1:50 pm-10:00 pm

1 stop11h 10m

$426

San DiegoGreenville

SAN - GSP

SANGSP

San Diego

Tue 6/2

9:15 am-9:40 pm

2 stops9h 25m

Greenville

Tue 6/9

1:50 pm-11:25 pm

1 stop12h 35m

$436

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from San Diego to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Greenville?

What is the cheapest month to fly to Greenville?

The month of June is another great option to travel to Greenville, with average flight prices from San Diego averaging around $406.

How have San Diego to Greenville flight prices changed over time?

As of April 2026, prices for San Diego to Greenville flights are approximately 24% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Greenville (SAN to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Greenville

Fastest flight time

6h 15m

Direct flights

None
The fastest flight from San Diego to Greenville takes 6h 15m
There are no direct flights from San Diego to Greenville. There are no popular flight routes from San Diego to Greenville.
Search flight deals

Frequently asked questions about flying from San Diego to Greenville

  • How far is San Diego to Greenville by plane?

    There are 1990.4 mi between San Diego and Greenville. A reasonable flight in good conditions will take 6h 15m.

  • When did momondo last update prices for flights from San Diego Airport to Greenville Airport?

    Prices for flights from San Diego Airport to Greenville Airport are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Greenville Airport?

  • How old do you have to be to fly from San Diego Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Greenville?

Best airlines flying from San Diego to Greenville

Compare and see reviews for airlines that fly from San Diego to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $286Free CancellationRating
7.1
11,673 reviews
Search American Airlines flights
DeltaPriceFrom $312Free CancellationRating
7.9
8,460 reviews
Search Delta flights
United AirlinesPriceFrom $358Free CancellationRating
7.4
9,657 reviews
Search United Airlines flights
SouthwestPriceFrom $398Free CancellationRating
8.0
4,327 reviews
Search Southwest flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Greenville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Greenville from San Diego.

Can I find flights from San Diego to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Greenville?

momondo helps you find the best flight between San Diego and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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