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Cheap flights from Pittsburgh to Florence from $443

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to Florence departing on 4/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:33 am - 3:50 pm
PIT
-
FLO
5h 17m
1 stop
American Airlines Logo
4:02 pm - 8:14 pm
FLO
-
PIT
4h 12m
1 stop
$579American Airlines
vie., abr. 17 - mar., abr. 21
American Airlines Logo
5:58 pm - 9:47 pm
PIT
-
FLO
3h 49m
1 stop
American Airlines Logo
4:02 pm - 11:21 pm
FLO
-
PIT
7h 19m
2 stops
$584American Airlines
vie., abr. 17 - mar., abr. 21
American Airlines Logo
6:54 am - 3:50 pm
PIT
-
FLO
8h 56m
2 stops
American Airlines Logo
6:15 am - 12:39 pm
FLO
-
PIT
6h 24m
2 stops
$589American Airlines
vie., abr. 17 - mar., abr. 21

American Airlines flights from Pittsburgh to Florence, South Carolina

Our best American Airlines deals on Pittsburgh to Florence, South Carolina flight tickets
American Airlines
Apr 17
PIT10:33 amPittsburgh
5h 17m
1 stop
FLO3:50 pmFlorence
Apr 21
FLO4:02 pmFlorence
4h 12m
1 stop
PIT8:14 pmPittsburgh
$579
American Airlines
Apr 17
PIT5:58 pmPittsburgh
3h 49m
1 stop
FLO9:47 pmFlorence
Apr 21
FLO4:02 pmFlorence
7h 19m
2 stops
PIT11:21 pmPittsburgh
$584
American Airlines
Apr 17
PIT6:54 amPittsburgh
8h 56m
2 stops
FLO3:50 pmFlorence
Apr 21
FLO6:15 amFlorence
6h 24m
2 stops
PIT12:39 pmPittsburgh
$589

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated abril 6, 2026.
Use the filters below to find and compare flights from Pittsburgh to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

vie. 4/17

10:33 am-3:50 pm

1 stop5h 17m

Florence

mar. 4/21

4:02 pm-8:14 pm

1 stop4h 12m

$579

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

vie. 4/17

5:58 pm-9:47 pm

1 stop3h 49m

Florence

mar. 4/21

4:02 pm-11:21 pm

2 stops7h 19m

$584

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

vie. 4/17

6:54 am-3:50 pm

2 stops8h 56m

Florence

mar. 4/21

6:15 am-12:39 pm

2 stops6h 24m

$589
Cheapest one-way
Quickest one-way

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

dom. 4/12

5:58 pm-9:47 pm

1 stop3h 49m

$443

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

dom. 4/12

8:24 am-3:50 pm

2 stops7h 26m

$448

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Pittsburgh to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Pittsburgh to Florence?

American Airlines is the most popular carrier operating from Pittsburgh to Florence

What airlines fly to Florence, South Carolina?

Allegiant Air, Spirit Airlines and American Airlines are the top three most popular airlines that fly to Florence, South Carolina from Pittsburgh according to our data. Allegiant Air is the first choice among our users, with 29% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Pittsburgh to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Pittsburgh to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Pittsburgh to Florence, South Carolina (PIT to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to Florence, South Carolina

Fastest flight time

5h 17m

Direct flights

None
The fastest flight from Pittsburgh to Florence, South Carolina takes 5h 17m
There are no direct flights from Pittsburgh to Florence, South Carolina. There are no popular flight routes from Pittsburgh to Florence, South Carolina.
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Frequently asked questions about flying from Pittsburgh to Florence, South Carolina

  • How far is Pittsburgh to Florence by plane?

    There are 431.4 mi between Pittsburgh and Florence. Typically, this will take 5h 17m by plane in normal conditions.

  • When did momondo last update prices for flights from Pittsburgh Airport to Florence Airport?

    Prices for flights from Pittsburgh Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Pittsburgh Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Pittsburgh Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Pittsburgh.

Can I find flights from Pittsburgh to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Pittsburgh which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Pittsburgh to Florence?

Once you have performed a search for Pittsburgh to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Pittsburgh to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Pittsburgh to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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