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Cheap flights from Pittsburgh to Florence from $413

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to Florence departing on 6/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Pittsburgh to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:31 pm - 10:00 pm
PIT
-
FLO
6h 29m
1 stop
American Airlines Logo
5:05 am - 4:17 pm
FLO
-
PIT
11h 12m
2 stops
$429American Airlines
Wed, Jun 17 - Tue, Jun 23
American Airlines Logo
10:55 am - 10:00 pm
PIT
-
FLO
11h 05m
2 stops
American Airlines Logo
5:05 am - 4:17 pm
FLO
-
PIT
11h 12m
2 stops
$434American Airlines
Wed, Jun 17 - Tue, Jun 23
American Airlines Logo
9:44 am - 2:10 pm
PIT
-
FLO
4h 26m
1 stop
American Airlines Logo
2:35 pm - 7:29 pm
FLO
-
PIT
4h 54m
1 stop
$473American Airlines
Wed, Jun 17 - Tue, Jun 23
American Airlines Logo
6:05 am - 3:40 pm
PIT
-
FLO
9h 35m
2 stops
American Airlines Logo
11:07 am - 5:44 pm
FLO
-
PIT
6h 37m
1 stop
$510American Airlines
Thu, Oct 1 - Mon, Oct 19
American Airlines Logo
6:05 am - 3:40 pm
PIT
-
FLO
9h 35m
2 stops
American Airlines Logo
2:17 pm - 10:17 pm
FLO
-
PIT
8h 00m
2 stops
$515American Airlines
Thu, Oct 1 - Mon, Oct 19
American Airlines Logo
9:44 am - 2:10 pm
PIT
-
FLO
4h 26m
1 stop
American Airlines Logo
2:35 pm - 7:29 pm
FLO
-
PIT
4h 54m
1 stop
$517American Airlines
Sat, Jun 20 - Fri, Jun 26
American Airlines Logo
1:08 pm - 10:00 pm
PIT
-
FLO
8h 52m
2 stops
American Airlines Logo
2:35 pm - 7:29 pm
FLO
-
PIT
4h 54m
1 stop
$522American Airlines
Sat, Jun 20 - Fri, Jun 26
American Airlines Logo
1:08 pm - 10:00 pm
PIT
-
FLO
8h 52m
2 stops
American Airlines Logo
2:35 pm - 9:16 pm
FLO
-
PIT
6h 41m
2 stops
$527American Airlines
Sat, Jun 20 - Fri, Jun 26
American Airlines Logo
6:52 am - 10:21 am
PIT
-
FLO
3h 29m
1 stop
American Airlines Logo
2:17 pm - 5:44 pm
FLO
-
PIT
3h 27m
1 stop
$561American Airlines
Thu, Oct 1 - Mon, Oct 19
American Airlines Logo
9:44 am - 2:10 pm
PIT
-
FLO
4h 26m
1 stop
American Airlines Logo
5:05 am - 4:25 pm
FLO
-
PIT
11h 20m
2 stops
$604American Airlines
Tue, Jun 2 - Mon, Jun 8

American Airlines flights from Pittsburgh to Florence, South Carolina

Our best American Airlines deals on Pittsburgh to Florence, South Carolina flight tickets
American Airlines
Jun 17
PIT3:31 pmPittsburgh
6h 29m
1 stop
FLO10:00 pmFlorence
Jun 23
FLO5:05 amFlorence
11h 12m
2 stops
PIT4:17 pmPittsburgh
$429
American Airlines
Jun 17
PIT10:55 amPittsburgh
11h 05m
2 stops
FLO10:00 pmFlorence
Jun 23
FLO5:05 amFlorence
11h 12m
2 stops
PIT4:17 pmPittsburgh
$434
American Airlines
Jun 17
PIT9:44 amPittsburgh
4h 26m
1 stop
FLO2:10 pmFlorence
Jun 23
FLO2:35 pmFlorence
4h 54m
1 stop
PIT7:29 pmPittsburgh
$473

momondo Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Pittsburgh to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Wed 6/17

3:31 pm-10:00 pm

1 stop6h 29m

Florence

Tue 6/23

5:05 am-4:17 pm

2 stops11h 12m

$429

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Wed 6/17

10:55 am-10:00 pm

2 stops11h 05m

Florence

Tue 6/23

5:05 am-4:17 pm

2 stops11h 12m

$434

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Wed 6/17

9:44 am-2:10 pm

1 stop4h 26m

Florence

Tue 6/23

2:35 pm-7:29 pm

1 stop4h 54m

$473

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Thu 10/1

6:05 am-3:40 pm

2 stops9h 35m

Florence

Mon 10/19

11:07 am-5:44 pm

1 stop6h 37m

$510

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Thu 10/1

6:05 am-3:40 pm

2 stops9h 35m

Florence

Mon 10/19

2:17 pm-10:17 pm

2 stops8h 00m

$515

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Sat 6/20

9:44 am-2:10 pm

1 stop4h 26m

Florence

Fri 6/26

2:35 pm-7:29 pm

1 stop4h 54m

$517

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Sat 6/20

1:08 pm-10:00 pm

2 stops8h 52m

Florence

Fri 6/26

2:35 pm-7:29 pm

1 stop4h 54m

$522

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Sat 6/20

1:08 pm-10:00 pm

2 stops8h 52m

Florence

Fri 6/26

2:35 pm-9:16 pm

2 stops6h 41m

$527
Quickest round-trip

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Thu 10/1

6:52 am-10:21 am

1 stop3h 29m

Florence

Mon 10/19

2:17 pm-5:44 pm

1 stop3h 27m

$561

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Tue 6/2

9:44 am-2:10 pm

1 stop4h 26m

Florence

Mon 6/8

5:05 am-4:25 pm

2 stops11h 20m

$604

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Pittsburgh to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Pittsburgh to Florence?

American Airlines is the most popular carrier operating from Pittsburgh to Florence

What airlines fly to Florence, South Carolina?

Allegiant Air, American Airlines and Spirit Airlines are the top three most popular airlines that fly to Florence, South Carolina from Pittsburgh according to our data. Allegiant Air is the first choice among our users, with 29% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Pittsburgh to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Pittsburgh to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Pittsburgh to Florence, South Carolina (PIT to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to Florence, South Carolina

Fastest flight time

6h 29m

Direct flights

None
The fastest flight from Pittsburgh to Florence, South Carolina takes 6h 29m
There are no direct flights from Pittsburgh to Florence, South Carolina. There are no popular flight routes from Pittsburgh to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Pittsburgh to Florence, South Carolina

  • How far is Pittsburgh to Florence by plane?

    There are 431.4 mi between Pittsburgh and Florence. Typically, this will take 6h 29m by plane in normal conditions.

  • When did momondo last update prices for flights from Pittsburgh Airport to Florence Airport?

    Prices for flights from Pittsburgh Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Pittsburgh Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Pittsburgh Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Pittsburgh.

Can I find flights from Pittsburgh to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Pittsburgh which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Pittsburgh to Florence?

Once you have performed a search for Pittsburgh to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Pittsburgh to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Pittsburgh to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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