Cheap flights from Pennsylvania to Panama City from $110

The cheapest month to fly to Panama City, Florida from Pennsylvania is in February. Flight prices, which tend to average around $353, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Panama City, Florida, with average flight prices from Pennsylvania averaging around $390.

Our data shows that Wednesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $375. On the other hand, Saturday is the most expensive day to depart from Pennsylvania because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $567.

Fly from Philadelphia to Panama City NW Florida Beaches for the best Pennsylvania - Panama City NW Florida Beaches flight prices

You are more likely to see cheaper flights to Panama City, Florida from Pennsylvania when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $434 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Pennsylvania for as low as $383 on momondo.

There are 2 cabin classes available to choose from on Pennsylvania to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 30% on your flight if you consider stops on a Pennsylvania to Panama City, Florida flight.

Delta, Southwest, and United Airlines are the most popular carriers operating from Pennsylvania to Panama City NW Florida Beaches

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Panama City, Florida from Pennsylvania according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 6 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

As of September 2026, there are 5 flights per week flying from Pennsylvania to Panama City, Florida. The most common day of the week flights depart is Mon, with 20% of flights taking off on this day.

Flight times vary depending on what airport in Pennsylvania you fly out of and what airport in Panama City, Florida you fly into. For example, flying from Philadelphia to Pensacola takes 2h 49m on average. On the other hand, flying from Pittsburgh to Pensacola takes 3h 39m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.